The network for 'negative regulation of biological process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of biological process

Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.984
vab-3Protein VAB-30.958
mig-5Protein MIG-50.946
gpr-1Protein GPR-10.923
aap-1Protein AAP-10.849
cam-1Protein CAM-10.817
egl-8Protein EGL-80.814
par-5Protein PAR-50.805
mat-3Protein MAT-30.761
snr-2Protein SNR-20.755
cacn-1Protein CACN-10.745
kle-2Protein KLE-20.744
unc-37Protein UNC-370.731
sas-5Protein SAS-50.728
egl-27Protein EGL-270.726
dlk-1Protein DLK-10.706
unc-62Protein UNC-620.704
F39B2.1Protein F39B2.10.699
hcf-1Protein HCF-10.699
hlh-2Protein HLH-20.683
pry-1Protein PRY-10.680
CELE_C24H12.5Protein C24H12.50.677
nhr-67Protein NHR-670.666
hcp-3Protein HCP-30.661
lin-25Protein LIN-250.658
pha-4Protein PHA-40.657
sur-2Protein SUR-20.651
B0336.3Protein B0336.30.642
unc-9Protein UNC-90.636
pkg-1Protein PKG-10.629
hbl-1Protein HBL-10.627
ubc-12Protein UBC-120.627
chc-1Protein CHC-10.623
mex-5Protein MEX-50.621
mab-5Protein MAB-50.612
gld-1Protein GLD-10.610
ima-3Protein IMA-30.608
pdfr-1Protein PDFR-10.605
gei-18Protein GEI-180.604
eor-1Protein EOR-10.602
ekl-6Protein EKL-60.589
goa-1Protein GOA-10.587
mei-1Protein MEI-10.585
rnr-1Protein RNR-10.583
sma-6Protein SMA-60.577
inx-5Protein INX-50.576
his-1Protein HIS-10.575
fkh-2Protein FKH-20.572
asb-2Protein ASB-20.571
npp-7Protein NPP-70.571
rde-1Protein RDE-10.571
tag-163Protein TAG-1630.570
fkb-6Protein FKB-60.568
bet-1Protein BET-10.568
F33D11.10Protein F33D11.100.568
lag-1Protein LAG-10.566
ahcy-1Protein AHCY-10.551
sas-6Protein SAS-60.544
ced-9Protein CED-90.544
pri-2Protein PRI-20.540
daf-12Protein DAF-120.539
lsy-2Protein LSY-20.539
xpo-1Protein XPO-10.535
let-60Protein LET-600.532
zip-7Protein ZIP-70.531
hum-5Protein HUM-50.530
patr-1Protein PATR-10.529
cpb-1Protein CPB-10.527
egl-13Protein EGL-130.525
F33E11.3Protein F33E11.30.519
bub-1Protein BUB-10.513
aak-2Protein AAK-20.512
npp-12Protein NPP-120.502
D1081.8Protein D1081.80.500
sas-4Protein SAS-40.498
epn-1Protein EPN-10.498
apr-1Protein APR-10.497
dph-1Protein DPH-10.494
lin-53Protein LIN-530.493
cki-1Protein CKI-10.493
ceh-100Protein CEH-1000.491
pmk-1Protein PMK-10.490
npp-4Protein NPP-40.487
alg-2Protein ALG-20.486
smc-3Protein SMC-30.484
nhr-25Protein NHR-250.483
mut-14Protein MUT-140.481
unc-43Protein UNC-430.480
CELE_F53C11.5Protein F53C11.50.479
let-23Protein LET-230.479
npp-19Protein NPP-190.479
sea-2Protein SEA-20.479
lmn-1Protein LMN-10.478
Y77E11A.6Protein Y77E11A.60.474
glp-1Protein GLP-10.471
rig-1Protein RIG-10.469
lir-1Protein LIR-10.468
aph-1Protein APH-10.464
dnj-13Protein DNJ-130.462
dlc-1Protein DLC-10.462
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
pax8paired box gene 80.995
fgf3fibroblast growth factor 30.992
tbx6T-box gene 60.990
spry4sprouty (Drosophila) homolog 40.987
tal1T-cell acute lymphocytic leukemia 10.987
fgfr2fibroblast growth factor receptor 20.980
cxcr4bchemokine (C-X-C motif), receptor 4b0.970
pkd2polycystic kidney disease 20.969
myod1myogenic differentiation 10.969
notch1anotch homolog 1a0.968
fgf8afibroblast growth factor 8 a0.967
sox2SRY-box containing gene 20.966
whsc1Wolf-Hirschhorn syndrome candidate 10.966
ezh2enhancer of zeste homolog 2 (Drosophila)0.958
ndr2nodal-related 20.957
tfap2atranscription factor AP-2 alpha0.955
klf4aKruppel-like transcription factor 4a0.952
prox1prospero-related homeobox gene 10.952
myf5myogenic factor 50.947
lhx1aLIM homeobox 1a0.935
khdrbs1aKH domain containing, RNA binding, signal transduction associated 1a0.935
gdf6agrowth differentiation factor 6a0.929
fgfr3fibroblast growth factor receptor 30.925
csrp1acysteine and glycine-rich protein 1a0.923
gata6GATA-binding protein 60.923
pax2apaired box gene 2a0.919
cxcr4achemokine (C-X-C motif) receptor 4a0.907
bdnfbrain-derived neurotrophic factor0.904
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.904
bmp2bbone morphogenetic protein 2b0.898
sox19aSRY-box containing gene 19a0.896
aldh1a2aldehyde dehydrogenase 1 family, member A20.895
lmx1b.1LIM homeobox transcription factor 1, beta 10.892
fn1fibronectin 10.889
kdrlkinase insert domain receptor like0.886
prdm1aPR domain containing 1a, with ZNF domain0.878
wnt11rwingless-type MMTV integration site family, member 11, related0.874
tbx2bT-box 2b0.872
dab1adisabled homolog 1a (Drosophila)0.872
her6hairy-related 60.872
acvr1lactivin A receptor, type I like0.869
alcambactivated leukocyte cell adhesion molecule b0.860
pea3ETS-domain transcription factor pea30.859
hmx1H6 homeo box 10.859
grem2gremlin 2, cysteine knot superfamily0.854
her1hairy-related 10.852
irx4biroquois homeobox protein 4b0.840
tcf7transcription factor 7 (T-cell specific, HMG-box)0.839
mpxmyeloid-specific peroxidase0.831
dlx5adistal-less homeobox gene 5a0.828
cyp26a1cytochrome P450, subfamily XXVIA, polypeptide 10.826
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.824
hhiphedgehog interacting protein0.824
evx1even-skipped homeobox 10.818
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.813
gata5GATA-binding protein 50.812
tgfb3transforming growth factor, beta 30.808
ascl1aachaete-scute complex-like 1a (Drosophila)0.806
kal1aKallmann syndrome 1a sequence0.803
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.803
brd4bromodomain containing 40.801
bmp4bone morphogenetic protein 40.800
jag2jagged 20.797
notch3notch homolog 30.793
mecomMDS1 and EVI1 complex locus0.792
tbx16T-box gene 160.790
cd63Cd63 antigen0.787
snai1asnail homolog 1a (Drosophila)0.786
dmbx1adiencephalon/mesencephalon homeobox 1a0.785
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.784
gro1groucho 10.781
runx2brunt-related transcription factor 2b0.777
pitx3paired-like homeodomain transcription factor 30.777
tll1tolloid-like 10.774
fzd7afrizzled homolog 7a0.768
tp53tumor protein p530.766
nkx2.2aNK2 transcription factor related 2a0.766
igf1rainsulin-like growth factor 1a receptor0.765
wnt2bbwingless-type MMTV integration site family, member 2Bb0.754
epb41l5erythrocyte membrane protein band 4.1 like 50.753
foxi1forkhead box I10.746
fzd7bfrizzled homolog 7b0.746
fosv-fos FBJ murine osteosarcoma viral oncogene homolog0.744
efnb2aephrin B2a0.743
ikzf1IKAROS family zinc finger 1 (Ikaros)0.739
prnprs3prion protein, related sequence 30.739
tgfbitransforming growth factor, beta-induced0.736
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.733
admpanti-dorsalizing morphogenic protein0.733
gata3GATA-binding protein 30.733
sst1.1somatostatin 1, tandem duplicate 10.727
otx5orthodenticle homolog 50.723
irx1airoquois homeobox protein 1, a0.719
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism