IMP
Process View
The network for 'peptide hormone processing' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
peptide hormone processing
The generation of a mature peptide hormone by posttranslational processing of a prohormone.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| pgal-1 | Protein PGAL-1 | 0.080 | |
| pghm-1 | Protein PGHM-1 | 0.060 | |
| CELE_Y49E10.16 | Protein Y49E10.16 | 0.046 | |
| egl-21 | Protein EGL-21 | 0.037 | |
| sbt-1 | Protein SBT-1 | 0.035 | |
| F10E7.9 | Protein F10E7.9 | 0.031 | |
| asp-2 | Protein ASP-2 | 0.027 | |
| far-1 | Protein FAR-1 | 0.027 | |
| K10C2.1 | Protein K10C2.1 | 0.026 | |
| flp-9 | Protein FLP-9 | 0.026 | |
| CELE_T27C4.1 | Protein T27C4.1 | 0.024 | |
| asb-2 | Protein ASB-2 | 0.023 | |
| CELE_F17C11.2 | Protein F17C11.2 | 0.023 | |
| egl-3 | Protein EGL-3 | 0.022 | |
| csq-1 | Protein CSQ-1 | 0.022 | |
| cab-1 | Protein CAB-1 | 0.022 | |
| C33A11.1 | Protein C33A11.1 | 0.021 | |
| gpd-3 | Protein GPD-3 | 0.020 | |
| F28B4.3 | Protein F28B4.3 | 0.019 | |
| abts-3 | Protein ABTS-3 | 0.019 | |
| mdl-1 | Protein MDL-1 | 0.018 | |
| lec-9 | Protein LEC-9 | 0.018 | |
| F32B5.6 | Protein F32B5.6 | 0.017 | |
| unc-13 | Protein UNC-13 | 0.016 | |
| F40F4.6 | Protein F40F4.6 | 0.016 | |
| nlp-13 | Protein NLP-13 | 0.016 | |
| lin-1 | Protein LIN-1 | 0.015 | |
| ZK822.4 | Protein ZK822.4 | 0.015 | |
| K10D6.4 | Protein K10D6.4 | 0.015 | |
| F09B12.3 | Protein F09B12.3 | 0.015 | |
| immt-1 | Protein IMMT-1 | 0.015 | |
| vha-6 | Protein VHA-6 | 0.015 | |
| aqp-2 | Protein AQP-2 | 0.015 | |
| tps-2 | Protein TPS-2 | 0.015 | |
| ida-1 | Protein IDA-1 | 0.014 | |
| F35B12.9 | Protein F35B12.9 | 0.014 | |
| rpl-11.2 | Protein RPL-11.2 | 0.014 | |
| tag-260 | Protein TAG-260 | 0.013 | |
| T08B1.1 | Protein T08B1.1 | 0.013 | |
| asp-5 | Protein ASP-5 | 0.013 | |
| CELE_W07A8.2 | Protein W07A8.2 | 0.013 | |
| cpz-2 | Protein CPZ-2 | 0.013 | |
| F13B6.3 | Protein F13B6.3 | 0.013 | |
| CELE_Y41C4A.13 | Protein Y41C4A.13 | 0.012 | |
| hlh-11 | Protein HLH-11 | 0.012 | |
| ceh-20 | Protein CEH-20 | 0.012 | |
| T06D8.1 | Protein T06D8.1 | 0.012 | |
| riok-2 | Protein RIOK-2 | 0.012 | |
| fat-3 | Protein FAT-3 | 0.012 | |
| rpl-25.1 | Protein RPL-25.1 | 0.012 | |
| ksr-2 | Protein KSR-2 | 0.012 | |
| gfi-1 | Protein GFI-1 | 0.011 | |
| aldo-1 | Protein ALDO-1 | 0.011 | |
| clec-63 | Protein CLEC-63 | 0.011 | |
| asp-6 | Protein ASP-6 | 0.011 | |
| pcca-1 | Protein PCCA-1 | 0.011 | |
| aagr-2 | Protein AAGR-2 | 0.011 | |
| R07E3.1 | Protein R07E3.1 | 0.011 | |
| F46G10.2 | Protein F46G10.2 | 0.010 | |
| flp-5 | Protein FLP-5 | 0.010 | |
| iff-2 | Protein IFF-2 | 0.010 | |
| sma-3 | Protein SMA-3 | 0.010 |
Loading network...
Drosophila melanogaster| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Vha68-2 | CG3762 gene product from transcript CG3762-RA | 0.032 | |
| PGRP-SD | CG7496 gene product from transcript CG7496-RA | 0.029 | |
| SPE | Spatzle-Processing Enzyme | 0.025 | |
| CG12262 | CG12262 gene product from transcript CG12262-RA | 0.021 | |
| LamC | Lamin C | 0.021 | |
| CG18284 | CG18284 gene product from transcript CG18284-RB | 0.019 | |
| VhaPPA1-1 | CG7007 gene product from transcript CG7007-RA | 0.018 | |
| CG8029 | CG8029 gene product from transcript CG8029-RB | 0.018 | |
| Sec61alpha | CG9539 gene product from transcript CG9539-RA | 0.018 | |
| CG8839 | CG8839 gene product from transcript CG8839-RA | 0.017 | |
| npf | neuropeptide F | 0.017 | |
| CG32528 | CG32528 gene product from transcript CG32528-RA | 0.017 | |
| fon | fondue | 0.015 | |
| Fer2LCH | Ferritin 2 light chain homologue | 0.015 | |
| CG17597 | CG17597 gene product from transcript CG17597-RA | 0.015 | |
| CG10992 | CG10992 gene product from transcript CG10992-RA | 0.015 | |
| CG5835 | CG5835 gene product from transcript CG5835-RA | 0.014 | |
| msopa | male-specific opa containing gene | 0.014 | |
| GNBP3 | Gram-negative bacteria binding protein 3 | 0.013 | |
| Spn28D | Serpin 28D | 0.013 | |
| Fer1HCH | Ferritin 1 heavy chain homologue | 0.013 | |
| CG4199 | CG4199 gene product from transcript CG4199-RG | 0.013 | |
| CG4572 | CG4572 gene product from transcript CG4572-RD | 0.012 | |
| Idgf3 | Imaginal disc growth factor 3 | 0.012 | |
| neo | neyo | 0.012 | |
| Mec2 | CG7635 gene product from transcript CG7635-RA | 0.011 | |
| Tsp42Ed | Tetraspanin 42Ed | 0.011 | |
| CG8909 | CG8909 gene product from transcript CG8909-RC | 0.011 | |
| psh | persephone | 0.011 | |
| CG4025 | CG4025 gene product from transcript CG4025-RA | 0.011 | |
| Spn4 | Serine protease inhibitor 4 | 0.010 | |
| CG10026 | CG10026 gene product from transcript CG10026-RA | 0.010 | |
| tmod | tropomodulin | 0.010 | |
| CG15905 | CG15905 gene product from transcript CG15905-RB | 0.010 |
Loading network...
Homo sapiens| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| PSAP | prosaposin | 0.125 | |
| CTSA | cathepsin A | 0.042 | |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.023 | |
| F2 | coagulation factor II (thrombin) | 0.014 | |
| GRN | granulin | 0.013 | |
| ITM2B | integral membrane protein 2B | 0.013 | |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | 0.011 | |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.011 |
Loading network...
Mus musculus| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.578 | |
| Agtr1a | angiotensin II receptor, type 1a | 0.433 | |
| Lepr | leptin receptor | 0.329 | |
| Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.296 | |
| Col4a3 | collagen, type IV, alpha 3 | 0.142 | |
| Ctsb | cathepsin B | 0.122 | |
| Slc12a1 | solute carrier family 12, member 1 | 0.103 | |
| Atp6v1a | ATPase, H+ transporting, lysosomal V1 subunit A | 0.101 | |
| Kcne1 | potassium voltage-gated channel, Isk-related subfamily, member 1 | 0.080 | |
| Nr3c2 | nuclear receptor subfamily 3, group C, member 2 | 0.077 | |
| Umod | uromodulin | 0.075 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.067 | |
| Glis2 | GLIS family zinc finger 2 | 0.064 | |
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.061 | |
| Wt1 | Wilms tumor 1 homolog | 0.057 | |
| Atp6v0b | ATPase, H+ transporting, lysosomal V0 subunit B | 0.056 | |
| Tgfb1 | transforming growth factor, beta 1 | 0.043 | |
| Aprt | adenine phosphoribosyl transferase | 0.042 | |
| Lamp1 | lysosomal-associated membrane protein 1 | 0.039 | |
| Wnt5a | wingless-related MMTV integration site 5A | 0.032 | |
| Atp2b2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.031 | |
| Pcdh15 | protocadherin 15 | 0.030 | |
| Aqp2 | aquaporin 2 | 0.029 | |
| Thbs2 | thrombospondin 2 | 0.028 | |
| Zbtb16 | zinc finger and BTB domain containing 16 | 0.027 | |
| Myt1 | myelin transcription factor 1 | 0.024 | |
| Scg2 | secretogranin II | 0.023 | |
| Srrm4 | serine/arginine repetitive matrix 4 | 0.023 | |
| Pigr | polymeric immunoglobulin receptor | 0.023 | |
| Pdzk1ip1 | PDZK1 interacting protein 1 | 0.022 | |
| Vegfa | vascular endothelial growth factor A | 0.022 | |
| Resp18 | regulated endocrine-specific protein 18 | 0.022 | |
| Rab25 | RAB25, member RAS oncogene family | 0.021 | |
| Bdkrb2 | bradykinin receptor, beta 2 | 0.021 | |
| Muc1 | mucin 1, transmembrane | 0.020 | |
| Lgmn | legumain | 0.019 | |
| Dnahc5 | dynein, axonemal, heavy chain 5 | 0.018 | |
| Slc44a4 | solute carrier family 44, member 4 | 0.018 | |
| Kcnq1 | potassium voltage-gated channel, subfamily Q, member 1 | 0.017 | |
| Cyp11b2 | cytochrome P450, family 11, subfamily b, polypeptide 2 | 0.017 | |
| Snap25 | synaptosomal-associated protein 25 | 0.017 | |
| Chga | chromogranin A | 0.017 | |
| Pdx1 | pancreatic and duodenal homeobox 1 | 0.017 | |
| Atp1a4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.017 | |
| Hoxa10 | homeobox A10 | 0.016 | |
| Lamp2 | lysosomal-associated membrane protein 2 | 0.015 | |
| Rab3b | RAB3B, member RAS oncogene family | 0.014 | |
| Slc4a5 | solute carrier family 4, sodium bicarbonate cotransporter, member 5 | 0.014 | |
| Lama2 | laminin, alpha 2 | 0.013 | |
| Stmn3 | stathmin-like 3 | 0.013 | |
| Tmem146 | transmembrane protein 146 | 0.013 | |
| Gnas | GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus | 0.013 | |
| Krt8 | keratin 8 | 0.013 | |
| Psap | prosaposin | 0.013 | |
| Vdr | vitamin D receptor | 0.012 | |
| Sel1l | sel-1 suppressor of lin-12-like (C. elegans) | 0.012 | |
| Myo7a | myosin VIIA | 0.012 | |
| Asah1 | N-acylsphingosine amidohydrolase 1 | 0.012 | |
| Dsg2 | desmoglein 2 | 0.012 | |
| Cldn3 | claudin 3 | 0.011 | |
| Foxa2 | forkhead box A2 | 0.011 | |
| Foxf1a | forkhead box F1a | 0.011 | |
| Sfrp1 | secreted frizzled-related protein 1 | 0.011 | |
| Spdef | SAM pointed domain containing ets transcription factor | 0.011 | |
| Ccdc39 | coiled-coil domain containing 39 | 0.011 | |
| Tagln3 | transgelin 3 | 0.011 | |
| Igf2r | insulin-like growth factor 2 receptor | 0.011 | |
| Elf3 | E74-like factor 3 | 0.010 | |
| Slc39a4 | solute carrier family 39 (zinc transporter), member 4 | 0.010 | |
| Grb7 | growth factor receptor bound protein 7 | 0.010 | |
| 0610031J06Rik | RIKEN cDNA 0610031J06 gene | 0.010 | |
| Nrsn1 | neurensin 1 | 0.010 | |
| Rasgrf1 | RAS protein-specific guanine nucleotide-releasing factor 1 | 0.010 |