The network for 'somatic stem cell division' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

somatic stem cell division

The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.

NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.462
lag-1Protein LAG-10.240
goa-1Protein GOA-10.228
sem-5Protein SEM-50.130
sel-8Protein SEL-80.092
ten-1Protein TEN-10.090
egl-30Protein EGL-300.087
Y119C1A.1Protein Y119C1A.10.051
H14A12.3Protein H14A12.30.049
edc-3Protein EDC-30.047
inx-3Protein INX-30.046
pry-1Protein PRY-10.042
let-60Protein LET-600.039
K10C3.4Protein K10C3.40.038
lat-1Protein LAT-10.038
srgp-1Protein SRGP-10.038
sel-10Protein SEL-100.035
cit-1.1Protein CIT-1.10.033
lag-2Protein LAG-20.033
cnd-1Protein CND-10.032
elt-6Protein ELT-60.032
skpt-1Protein SKPT-10.031
tax-6Protein TAX-60.030
R02F11.4Protein R02F11.40.029
daf-1Protein DAF-10.028
R144.5Protein R144.50.028
dcap-2Protein DCAP-20.025
sun-1Protein SUN-10.024
lin-9Protein LIN-90.024
sma-6Protein SMA-60.023
tbg-1Protein TBG-10.022
cmd-1Protein CMD-10.022
Y59E9AL.4Protein Y59E9AL.40.021
pal-1Protein PAL-10.021
kin-18Protein KIN-180.021
CELE_C25A1.5Protein C25A1.50.020
tbb-4Protein TBB-40.020
lin-29Protein LIN-290.019
air-1Protein AIR-10.019
T26C12.1Protein T26C12.10.018
mes-4Protein MES-40.018
par-3Protein PAR-30.018
pxf-1Protein PXF-10.016
pde-4Protein PDE-40.016
B0464.6Protein B0464.60.016
T12B3.4Protein T12B3.40.015
par-5Protein PAR-50.015
pptr-2Protein PPTR-20.015
hlh-2Protein HLH-20.015
peb-1Protein PEB-10.014
C38C10.2Protein C38C10.20.014
men-1Protein MEN-10.014
nmy-2Protein NMY-20.014
F39B2.1Protein F39B2.10.014
bar-1Protein BAR-10.014
par-1Protein PAR-10.014
gpb-1Protein GPB-10.014
mys-1Protein MYS-10.014
daf-5Protein DAF-50.014
bath-43Protein BATH-430.014
unc-32Protein UNC-320.013
pct-1Protein PCT-10.013
sel-12Protein SEL-120.013
CELE_Y39E4B.2Protein Y39E4B.20.013
nhr-6Protein NHR-60.013
ZK180.3Protein ZK180.30.013
F36D4.5Protein F36D4.50.013
mes-3Protein MES-30.013
hbl-1Protein HBL-10.013
T23F11.1Protein T23F11.10.012
CELE_C50B6.3Protein C50B6.30.012
sec-16Protein SEC-160.011
ced-5Protein CED-50.011
Y7A9D.1Protein Y7A9D.10.011
smc-4Protein SMC-40.011
pig-1Protein PIG-10.011
F25B5.5Protein F25B5.50.011
glp-1Protein GLP-10.011
rab-11.1Protein RAB-11.10.011
daf-12Protein DAF-120.011
CELE_F53C11.5Protein F53C11.50.011
cdc-42Protein CDC-420.011
magi-1Protein MAGI-10.011
Y55F3BR.8Protein Y55F3BR.80.011
tag-168Protein TAG-1680.010
tat-1Protein TAT-10.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
G-ialpha65AG protein alphai subunit 65A0.923
Sas-4CG10061 gene product from transcript CG10061-RA0.860
SAKSak kinase0.760
sas-6spindle assembly abnormal 60.437
drkdownstream of receptor kinase0.397
CG15436CG15436 gene product from transcript CG15436-RA0.330
Ggamma1G protein gamma 10.323
Cdk4Cyclin-dependent kinase 40.267
CG5690CG5690 gene product from transcript CG5690-RA0.253
G-oalpha47AG protein oalpha 47A0.239
prodproliferation disrupter0.236
elavembryonic lethal abnormal vision0.235
nkdnaked cuticle0.230
Poc1Proteome of centrioles 10.228
myoglianinCG1838 gene product from transcript CG1838-RD0.220
lkb1CG9374 gene product from transcript CG9374-RJ0.205
numbCG3779 gene product from transcript CG3779-RB0.189
eveeven skipped0.189
ShcSHC-adaptor protein0.165
Dhc64CDynein heavy chain 64C0.162
EphrinCG1862 gene product from transcript CG1862-RA0.160
l(2)gllethal (2) giant larvae0.157
sinaseven in absentia0.152
fasfaint sausage0.136
chbchromosome bows0.119
CG2865CG2865 gene product from transcript CG2865-RA0.118
Rab5Rab-protein 50.116
locolocomotion defects0.102
CG6954CG6954 gene product from transcript CG6954-RB0.102
Grip71CG10346 gene product from transcript CG10346-RA0.098
l(2)05714lethal (2) 057140.096
gcmglial cells missing0.086
trioCG18214 gene product from transcript CG18214-RA0.081
PPP4R2rProtein phosphatase 4 regulatory subunit 2-related protein0.080
ana3anastral spindle 30.079
CG14667CG14667 gene product from transcript CG14667-RA0.075
Ctr1ACopper transporter 1A0.072
BicDBicaudal D0.071
emcextra macrochaetae0.071
CG5180CG5180 gene product from transcript CG5180-RB0.068
cdicenter divider0.066
CG4813CG4813 gene product from transcript CG4813-RA0.063
CG11560CG11560 gene product from transcript CG11560-RA0.061
Akt1CG4006 gene product from transcript CG4006-RA0.060
dcodiscs overgrown0.058
CG3995CG3995 gene product from transcript CG3995-RA0.058
par-6CG5884 gene product from transcript CG5884-RA0.056
stumpsCG31317 gene product from transcript CG31317-RC0.055
reporeversed polarity0.054
Cp110CG14617 gene product from transcript CG14617-RB0.047
poloCG12306 gene product from transcript CG12306-RA0.047
unc-5CG8166 gene product from transcript CG8166-RA0.046
Pkc98EProtein C kinase 98E0.046
Src64BSrc oncogene at 64B0.045
Ced-12CG5336 gene product from transcript CG5336-RA0.044
Cep135CG17081 gene product from transcript CG17081-RB0.044
tremtrade embargo0.044
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PRKCZprotein kinase C, zeta1.000
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme1.000
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)1.000
CCT8chaperonin containing TCP1, subunit 8 (theta)0.999
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.996
CDK2cyclin-dependent kinase 20.995
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.995
FGF1fibroblast growth factor 1 (acidic)0.994
STK11serine/threonine kinase 110.993
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.989
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.980
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.978
MAPTmicrotubule-associated protein tau0.973
JUBjub, ajuba homolog (Xenopus laevis)0.973
CDK1cyclin-dependent kinase 10.966
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.947
PKP2plakophilin 20.912
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.892
PRKCIprotein kinase C, iota0.880
CENPJcentromere protein J0.869
JAG1jagged 10.855
ZBED1zinc finger, BED-type containing 10.824
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha0.811
AP2A1adaptor-related protein complex 2, alpha 1 subunit0.772
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.760
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.733
SASS6spindle assembly 6 homolog (C. elegans)0.712
KITLGKIT ligand0.683
KIF23kinesin family member 230.648
ECT2epithelial cell transforming sequence 2 oncogene0.631
CCT4chaperonin containing TCP1, subunit 4 (delta)0.622
GSK3Bglycogen synthase kinase 3 beta0.616
CAPNS1calpain, small subunit 10.596
RBFOX1RNA binding protein, fox-1 homolog (C. elegans) 10.564
PPP2R1Bprotein phosphatase 2, regulatory subunit A, beta0.564
NGFnerve growth factor (beta polypeptide)0.563
TNIP2TNFAIP3 interacting protein 20.532
SPRED1sprouty-related, EVH1 domain containing 10.531
FGF10fibroblast growth factor 100.525
STILSCL/TAL1 interrupting locus0.510
NTF4neurotrophin 40.494
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.489
PKP3plakophilin 30.484
NOTCH3notch 30.443
QKIquaking homolog, KH domain RNA binding (mouse)0.425
GRB7growth factor receptor-bound protein 70.419
CCND1cyclin D10.400
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.397
BADBCL2-associated agonist of cell death0.388
STRADBSTE20-related kinase adaptor beta0.388
CDC25Bcell division cycle 25 homolog B (S. pombe)0.379
LLGL1lethal giant larvae homolog 1 (Drosophila)0.354
PPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma0.341
CCNB2cyclin B20.332
CCNE1cyclin E10.332
FYNFYN oncogene related to SRC, FGR, YES0.329
CDK6cyclin-dependent kinase 60.312
ARHGEF2Rho/Rac guanine nucleotide exchange factor (GEF) 20.297
CCND3cyclin D30.293
OXSR1oxidative-stress responsive 10.291
LLGL2lethal giant larvae homolog 2 (Drosophila)0.282
IRS1insulin receptor substrate 10.280
PLK4polo-like kinase 40.278
SKA3spindle and kinetochore associated complex subunit 30.278
LAD1ladinin 10.277
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.276
MARK2MAP/microtubule affinity-regulating kinase 20.276
SNCAsynuclein, alpha (non A4 component of amyloid precursor)0.270
DKK1dickkopf homolog 1 (Xenopus laevis)0.263
GNG2guanine nucleotide binding protein (G protein), gamma 20.261
RNF2ring finger protein 20.256
PTENphosphatase and tensin homolog0.234
STRADASTE20-related kinase adaptor alpha0.232
SKA1spindle and kinetochore associated complex subunit 10.227
DLGAP5discs, large (Drosophila) homolog-associated protein 50.225
NUMA1nuclear mitotic apparatus protein 10.215
SMURF2SMAD specific E3 ubiquitin protein ligase 20.208
KIF14kinesin family member 140.207
AKT1v-akt murine thymoma viral oncogene homolog 10.207
APPamyloid beta (A4) precursor protein0.202
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.199
CCNB1cyclin B10.189
CCDC158coiled-coil domain containing 1580.188
LRRK2leucine-rich repeat kinase 20.188
NCF2neutrophil cytosolic factor 20.181
MARK4MAP/microtubule affinity-regulating kinase 40.178
SKP2S-phase kinase-associated protein 2 (p45)0.174
FGF7fibroblast growth factor 70.172
TNS4tensin 40.171
GPRIN2G protein regulated inducer of neurite outgrowth 20.166
GNAI1guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 10.160
PAK3p21 protein (Cdc42/Rac)-activated kinase 30.159
FZD1frizzled homolog 1 (Drosophila)0.157
CEP55centrosomal protein 55kDa0.154
ANLNanillin, actin binding protein0.151
STK39serine threonine kinase 390.150
ERRFI1ERBB receptor feedback inhibitor 10.143
SKA2spindle and kinetochore associated complex subunit 20.143
TRAF5TNF receptor-associated factor 50.139
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 20.938
Gli3GLI-Kruppel family member GLI30.842
Ctnnb1catenin (cadherin associated protein), beta 10.689
Pax2paired box gene 20.649
Wnt3awingless-related MMTV integration site 3A0.567
Hoxb3homeobox B30.539
Hoxa1homeobox A10.526
Sox2SRY-box containing gene 20.509
Lef1lymphoid enhancer binding factor 10.496
Hoxb6homeobox B60.461
Rnf2ring finger protein 20.416
Dll1delta-like 1 (Drosophila)0.411
Pcsk5proprotein convertase subtilisin/kexin type 50.401
Hoxd9homeobox D90.384
Ptk7PTK7 protein tyrosine kinase 70.366
Wnt5awingless-related MMTV integration site 5A0.328
Hoxb5homeobox B50.315
Shhsonic hedgehog0.290
Hoxa5homeobox A50.282
Hoxa2homeobox A20.281
Tbx3T-box 30.274
RybpRING1 and YY1 binding protein0.248
Hoxa10homeobox A100.240
Appamyloid beta (A4) precursor protein0.206
Axin1axin 10.192
Hoxc5homeobox C50.179
Hoxc9homeobox C90.171
Pax8paired box gene 80.162
Esr1estrogen receptor 1 (alpha)0.158
Gli1GLI-Kruppel family member GLI10.135
Twist2twist homolog 2 (Drosophila)0.133
Pou3f3POU domain, class 3, transcription factor 30.132
Rargretinoic acid receptor, gamma0.127
Hoxc6homeobox C60.127
Fgfr1fibroblast growth factor receptor 10.124
Psen1presenilin 10.124
Bmp4bone morphogenetic protein 40.122
Nr2f2nuclear receptor subfamily 2, group F, member 20.119
Fzd8frizzled homolog 8 (Drosophila)0.119
Hoxd11homeobox D110.107
Ror1receptor tyrosine kinase-like orphan receptor 10.106
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.102
Lrp6low density lipoprotein receptor-related protein 60.099
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.091
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.087
Dlg4discs, large homolog 4 (Drosophila)0.086
Tbx2T-box 20.086
Meox2mesenchyme homeobox 20.085
Lama5laminin, alpha 50.084
Hoxb4homeobox B40.081
Gata3GATA binding protein 30.080
Tcf7l1transcription factor 7-like 1 (T-cell specific, HMG box)0.077
Hoxd8homeobox D80.077
Gas1growth arrest specific 10.074
Fgf10fibroblast growth factor 100.073
Rararetinoic acid receptor, alpha0.072
Gdnfglial cell line derived neurotrophic factor0.072
Prrx2paired related homeobox 20.072
Dvl3dishevelled 3, dsh homolog (Drosophila)0.067
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.065
Rarbretinoic acid receptor, beta0.064
Notch2Notch gene homolog 2 (Drosophila)0.062
Hoxa11homeobox A110.062
Arandrogen receptor0.061
Hoxa4homeobox A40.061
Wnt4wingless-related MMTV integration site 40.060
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.058
Trp63transformation related protein 630.058
Gopcgolgi associated PDZ and coiled-coil motif containing0.058
Fzd1frizzled homolog 1 (Drosophila)0.057
Pax3paired box gene 30.057
Fgf2fibroblast growth factor 20.056
Gpc3glypican 30.055
Emid2EMI domain containing 20.055
Gli2GLI-Kruppel family member GLI20.053
Hic1hypermethylated in cancer 10.053
Pbx1pre B-cell leukemia transcription factor 10.052
Dlx5distal-less homeobox 50.052
Ror2receptor tyrosine kinase-like orphan receptor 20.051
Msx2homeobox, msh-like 20.049
Vangl2vang-like 2 (van gogh, Drosophila)0.048
Hoxd4homeobox D40.047
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.046
Cdkn1bcyclin-dependent kinase inhibitor 1B0.045
Gdf11growth differentiation factor 110.044
Phc2polyhomeotic-like 2 (Drosophila)0.044
Dkk1dickkopf homolog 1 (Xenopus laevis)0.044
Bcl2B-cell leukemia/lymphoma 20.042
Cbx7chromobox homolog 70.042
Tead3TEA domain family member 30.042
Ctnna1catenin (cadherin associated protein), alpha 10.041
Ptf1apancreas specific transcription factor, 1a0.041
Pcgf2polycomb group ring finger 20.040
Lhx1LIM homeobox protein 10.040
Fgf8fibroblast growth factor 80.040
Pax7paired box gene 70.039
Prrx1paired related homeobox 10.039
Neurod1neurogenic differentiation 10.039
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.037
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.310
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.224
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.104
Fkbp1aFK506 binding protein 1a0.093
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.083
Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.081
Abcc1ATP-binding cassette, subfamily C (CFTR/MRP), member 10.078
Atp1b3ATPase, Na+/K+ transporting, beta 3 polypeptide0.070
Ppp2r2aprotein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform0.065
Sc65synaptonemal complex protein SC650.063
Cltcclathrin, heavy chain (Hc)0.062
RragaRas-related GTP binding A0.060
Map2k1mitogen activated protein kinase kinase 10.058
RhdRh blood group, D antigen0.057
Ptp4a1protein tyrosine phosphatase type IVA, member 10.054
Cux1cut-like homeobox 10.052
Pias2protein inhibitor of activated STAT, 20.049
Eif4heukaryotic translation initiation factor 4H0.048
Unc5bunc-5 homolog B (C. elegans)0.046
Mcammelanoma cell adhesion molecule0.044
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.043
Eif4g3eukaryotic translation initiation factor 4 gamma, 30.040
Rbbp7retinoblastoma binding protein 70.039
Nfianuclear factor I/A0.038
Nckap1NCK-associated protein 10.037
Bmp6bone morphogenetic protein 60.037
Racgap1Rac GTPase-activating protein 10.037
Nek9NIMA (never in mitosis gene a)- related kinase 90.037
Dock1dedicator of cyto-kinesis 10.037
Nlgn3neuroligin 30.036
Gfra2GDNF family receptor alpha 20.034
Nedd4neural precursor cell expressed, developmentally down-regulated 40.034
Atp2b3ATPase, Ca++ transporting, plasma membrane 30.034
Dchs1dachsous 1 (Drosophila)0.034
Slit3slit homolog 3 (Drosophila)0.033
Hprt1hypoxanthine phosphoribosyltransferase 10.033
Hrnbp3hexaribonucleotide binding protein 30.033
Pdia6protein disulfide isomerase family A, member 60.031
Mpripmyosin phosphatase Rho interacting protein0.030
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.030
Dock6dedicator of cytokinesis 60.030
Hspd1heat shock protein 1 (chaperonin)0.029
Pik3cdphosphoinositide-3-kinase, catalytic, delta polypeptide0.029
Actn4actinin alpha 40.029
Map3k3mitogen activated protein kinase kinase kinase 30.029
Celsr2cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)0.029
Tcf4transcription factor 40.028
Arnt2aryl hydrocarbon receptor nuclear translocator 20.028
Cabin1calcineurin binding protein 10.027
Basp1brain abundant, membrane attached signal protein 10.027
Smad2SMAD family member 20.027
Myt1lmyelin transcription factor 1-like0.026
Arpc2actin related protein 2/3 complex, subunit 20.026
Cskc-src tyrosine kinase0.026
Aldh1a2aldehyde dehydrogenase 1 family, member A20.026
Ppapdc1aphosphatidic acid phosphatase type 2 domain containing 1A0.026
Hk1hexokinase 10.025
Epn2epsin 20.025
FynFYN oncogene related to SRC, FGR, YES0.025
Prr5lproline rich 5 like0.025
Gng7guanine nucleotide binding protein (G protein), gamma 70.025
Rgs19regulator of G-protein signaling 190.024
Rhobras homolog gene family, member B0.024
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.024
Coro1bcoronin, actin-binding protein, 1B0.023
Pcnaproliferating cell nuclear antigen0.023
Ccnd3cyclin D30.023
Itgb7integrin, beta 70.023
Brafv-raf murine sarcoma viral oncogene homolog B10.023
Tbkbp1TBK1 binding protein 10.023
Golgb1golgin B1, golgi integral membrane protein0.023
Hn1hematological and neurological expressed 10.023
Akt1v-akt murine thymoma viral oncogene homolog 10.022
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.022
Fapfibroblast activation protein, alpha0.022
Ppp1caprotein phosphatase 1, catalytic subunit, alpha isoform0.022
Smad7SMAD family member 70.022
Gdf10growth differentiation factor 100.022
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.022
Bbxbobby sox homolog (Drosophila)0.022
Itgb1integrin, beta 10.022
Pak3p21 protein (Cdc42/Rac)-activated kinase 30.022
Serbp1Serpine1 mRNA binding protein 10.022
Pttg1pituitary tumor-transforming 10.022
Dgkgdiacylglycerol kinase, gamma0.022
Arpp21cAMP-regulated phosphoprotein 210.022
Clec11aC-type lectin domain family 11, member a0.021
Has2hyaluronan synthase 20.021
Rab6aRAB6A, member RAS oncogene family0.021
Matkmegakaryocyte-associated tyrosine kinase0.021
Sstr1somatostatin receptor 10.021
Mapk6mitogen-activated protein kinase 60.021
Robo2roundabout homolog 2 (Drosophila)0.021
Top2atopoisomerase (DNA) II alpha0.021
Cthrc1collagen triple helix repeat containing 10.020
Scn3bsodium channel, voltage-gated, type III, beta0.020
Rab7aRAB7A, member RAS oncogene family0.020
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.020
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism