The network for 'positive regulation of alkaline phosphatase activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of alkaline phosphatase activity

Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.

NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Hdac4histone deacetylase 40.438
Ppargperoxisome proliferator activated receptor gamma0.333
Agtr2angiotensin II receptor, type 20.307
Mef2cmyocyte enhancer factor 2C0.274
Vdrvitamin D receptor0.225
Hdac7histone deacetylase 70.220
Il6stinterleukin 6 signal transducer0.161
Hdac5histone deacetylase 50.142
Smad4MAD homolog 4 (Drosophila)0.129
Mef2dmyocyte enhancer factor 2D0.096
Leprleptin receptor0.091
Apcadenomatosis polyposis coli0.055
Axin1axin 10.053
Ttntitin0.053
Dmddystrophin, muscular dystrophy0.038
Nr3c1nuclear receptor subfamily 3, group C, member 10.034
Ptenphosphatase and tensin homolog0.033
Gucy1b3guanylate cyclase 1, soluble, beta 30.031
Cacna2d1calcium channel, voltage-dependent, alpha2/delta subunit 10.028
Ncoa3nuclear receptor coactivator 30.025
Qkquaking0.025
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.024
Larp1La ribonucleoprotein domain family, member 10.023
Kif1bkinesin family member 1B0.020
Zbtb20zinc finger and BTB domain containing 200.020
Tlr2toll-like receptor 20.019
Zeb2zinc finger E-box binding homeobox 20.019
Gucy1a3guanylate cyclase 1, soluble, alpha 30.019
Ptgs2prostaglandin-endoperoxide synthase 20.018
Arandrogen receptor0.018
Cav1caveolin 1, caveolae protein0.017
Smad2MAD homolog 2 (Drosophila)0.016
Tcf4transcription factor 40.016
Usp10ubiquitin specific peptidase 100.015
Hivep2human immunodeficiency virus type I enhancer binding protein 20.015
Ncoa1nuclear receptor coactivator 10.015
Nfixnuclear factor I/X0.015
Tgfbr1transforming growth factor, beta receptor I0.015
Ppp3caprotein phosphatase 3, catalytic subunit, alpha isoform0.014
Bcl2B-cell leukemia/lymphoma 20.014
Vhlvon Hippel-Lindau tumor suppressor0.014
Slc8a1solute carrier family 8 (sodium/calcium exchanger), member 10.014
Grwd1glutamate-rich WD repeat containing 10.014
Smad5MAD homolog 5 (Drosophila)0.013
Ankprogressive ankylosis0.013
Trp53transformation related protein 530.013
Spnb2spectrin beta 20.012
Prkg1protein kinase, cGMP-dependent, type I0.012
Vldlrvery low density lipoprotein receptor0.012
Nos3nitric oxide synthase 3, endothelial cell0.012
Ank3ankyrin 3, epithelial0.012
RoraRAR-related orphan receptor alpha0.012
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.012
Gpm6bglycoprotein m6b0.011
Hdac9histone deacetylase 90.011
St3gal2ST3 beta-galactoside alpha-2,3-sialyltransferase 20.010
Ebf1early B-cell factor 10.010
Kitlkit ligand0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.060
Tgfbr2transforming growth factor, beta receptor II0.044
Clic4chloride intracellular channel 40.042
Slco2a1solute carrier organic anion transporter family, member 2a10.034
RestRE1-silencing transcription factor0.022
Ednraendothelin receptor type A0.022
Myh9myosin, heavy chain 9, non-muscle0.019
Ptafrplatelet-activating factor receptor0.017
B4galt1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 10.016
Efnb1ephrin B10.015
Podxlpodocalyxin-like0.014
Fgfr2fibroblast growth factor receptor 20.014
Adam9ADAM metallopeptidase domain 9 (meltrin gamma)0.013
Dmddystrophin0.013
Lrrc33leucine rich repeat containing 330.013
Ptprkprotein tyrosine phosphatase, receptor type, K, extracellular region0.013
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.013
Cald1caldesmon 10.012
Akt1v-akt murine thymoma viral oncogene homolog 10.012
Bnip2BCL2/adenovirus E1B interacting protein 20.012
Elf1E74-like factor 10.012
Gna12guanine nucleotide binding protein (G protein) alpha 120.012
Olfml2bolfactomedin-like 2B0.012
Slc4a1solute carrier family 4 (anion exchanger), member 10.012
Slco2b1solute carrier organic anion transporter family, member 2b10.012
Cishcytokine inducible SH2-containing protein0.011
RGD1564560similar to RCK0.011
Txnrd1thioredoxin reductase 10.011
Lamc1laminin, gamma 10.011
Calcrlcalcitonin receptor-like0.011
Smad1SMAD family member 10.010
Cpsf2cleavage and polyadenylation specific factor 20.010
Syt8synaptotagmin VIII0.010
Mpeg1macrophage expressed 10.010
Myo10myosin X0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism