The network for 'chromosome organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

chromosome organization

A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.

NameDescriptionProbabilityFunc Analog Organism
zyg-9Protein ZYG-90.855
bub-1Protein BUB-10.824
cul-2Protein CUL-20.724
ima-2Protein IMA-20.679
npp-19Protein NPP-190.670
his-5Protein HIS-50.652
air-2Protein AIR-20.642
F33E11.3Protein F33E11.30.630
his-16Protein HIS-160.622
dcr-1Protein DCR-10.603
syx-4Protein SYX-40.583
ndc-80Protein NDC-800.558
rfc-4Protein RFC-40.557
CELE_F19F10.9Protein F19F10.90.553
C01H6.9Protein C01H6.90.550
hda-1Protein HDA-10.545
mcm-7Protein MCM-70.530
his-31Protein HIS-310.518
lex-1Protein LEX-10.500
sdc-1Protein SDC-10.485
his-1Protein HIS-10.480
rnr-1Protein RNR-10.480
F33H2.3Protein F33H2.30.479
bmk-1Protein BMK-10.478
hcp-3Protein HCP-30.467
klp-18Protein KLP-180.453
sas-5Protein SAS-50.449
mcm-3Protein MCM-30.448
ZK328.4Protein ZK328.40.444
B0336.3Protein B0336.30.441
iff-1Protein IFF-10.440
bar-1Protein BAR-10.426
htz-1Protein HTZ-10.411
crn-1Protein CRN-10.407
D1081.8Protein D1081.80.405
vrk-1Protein VRK-10.398
wrm-1Protein WRM-10.397
trr-1Protein TRR-10.396
ucr-2.3Protein UCR-2.30.395
rpa-1Protein RPA-10.379
D2096.11Protein D2096.110.378
lin-53Protein LIN-530.374
ttm-4Protein TTM-40.373
B0035.1Protein B0035.10.357
rpn-1Protein RPN-10.355
F25H5.5Protein F25H5.50.354
ung-1Protein UNG-10.352
mac-1Protein MAC-10.351
smc-3Protein SMC-30.350
baf-1Protein BAF-10.346
mix-1Protein MIX-10.338
F33H1.4Protein F33H1.40.336
mcm-5Protein MCM-50.336
pha-4Protein PHA-40.334
nasp-1Protein NASP-10.333
acs-4Protein ACS-40.333
sas-4Protein SAS-40.332
srgp-1Protein SRGP-10.332
kle-2Protein KLE-20.324
brc-1Protein BRC-10.324
mcm-2Protein MCM-20.321
csc-1Protein CSC-10.318
rod-1Protein ROD-10.314
rha-1Protein RHA-10.306
ama-1Protein AMA-10.306
his-42Protein HIS-420.306
lin-61Protein LIN-610.304
szy-20Protein SZY-200.302
efl-1Protein EFL-10.300
hil-3Protein HIL-30.300
his-4Protein HIS-40.297
R11A8.7Protein R11A8.70.291
his-29Protein HIS-290.290
hcp-2Protein HCP-20.283
lin-35Protein LIN-350.281
CELE_B0238.11Protein B0238.110.281
knl-1Protein KNL-10.277
CELE_C56A3.8Protein C56A3.80.275
tra-4Protein TRA-40.274
usp-46Protein USP-460.273
aipl-1Protein AIPL-10.268
dpl-1Protein DPL-10.268
rde-2Protein RDE-20.267
rba-1Protein RBA-10.267
B0412.3Protein B0412.30.264
kbp-5Protein KBP-50.261
rnr-2Protein RNR-20.259
his-9Protein HIS-90.258
isw-1Protein ISW-10.253
tag-135Protein TAG-1350.247
CELE_K08F4.1Protein K08F4.10.242
C05D11.7Protein C05D11.70.240
mig-32Protein MIG-320.237
sas-6Protein SAS-60.237
aspm-1Protein ASPM-10.237
unc-85Protein UNC-850.234
lin-5Protein LIN-50.233
T02G5.12Protein T02G5.120.233
his-64Protein HIS-640.231
brf-1Protein BRF-10.226
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
pcnaproliferating cell nuclear antigen0.997
suv39h1bsuppressor of variegation 3-9 homolog 1b0.841
naspnuclear autoantigenic sperm protein (histone-binding)0.838
nanos3nanos homolog 30.836
spry4sprouty (Drosophila) homolog 40.616
ncapd2non-SMC condensin I complex, subunit D20.532
gro2groucho 20.528
smc3structural maintenance of chromosomes 30.495
hp1bp3heterochromatin protein 1, binding protein 30.472
ncor1nuclear receptor co-repressor 10.459
smc4structural maintenance of chromosomes 40.455
her6hairy-related 60.453
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.448
ccnb1cyclin B10.432
kdm5clysine (K)-specific demethylase 5C0.431
fen1flap structure-specific endonuclease 10.407
ikzf1IKAROS family zinc finger 1 (Ikaros)0.406
ash2lash2 (absent, small, or homeotic)-like (Drosophila)0.395
brca2breast cancer 2, early onset0.362
ezh2enhancer of zeste homolog 2 (Drosophila)0.342
hoxa11bhomeo box A11b0.319
setdb1aSET domain, bifurcated 1a0.301
osr1odd-skipped related 1 (Drosophila)0.286
ep300bE1A binding protein p300 b0.278
ywhabatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a0.256
pold1polymerase (DNA directed), delta 1, catalytic subunit0.253
smyd2aSET and MYND domain containing 2a0.250
supt5hsuppressor of Ty 5 homolog (S. cerevisiae)0.245
mosv-mos Moloney murine sarcoma viral oncogene homolog0.241
anp32aacidic (leucine-rich) nuclear phosphoprotein 32 family, member A0.223
setdb1bSET domain, bifurcated 1b0.222
suv39h1asuppressor of variegation 3-9 homolog 1a0.220
ube2iubiquitin-conjugating enzyme E2I0.205
rbb4lretinoblastoma binding protein 4, like0.204
tipintimeless interacting protein0.203
ube2i2ubiquitin-conjugating enzyme E2I20.201
brd3abromodomain containing 3a0.196
slc2a10solute carrier family 2 (facilitated glucose transporter), member 100.185
rpa1replication protein A10.181
sass6spindle assembly 6 homolog (C. elegans)0.179
atad5aATPase family, AAA domain containing 5a0.178
rcc2regulator of chromosome condensation 20.177
pbrm1lpolybromo 1, like0.177
ccna2cyclin A20.176
ncaphnon-SMC condensin I complex, subunit H0.171
fanclFanconi anemia, complementation group L0.159
znf703zinc finger protein 7030.159
ssrp1astructure specific recognition protein 1a0.159
setd8bSET domain containing (lysine methyltransferase) 8b0.158
hoxd4ahomeo box D4a0.157
rbb4retinoblastoma binding protein 40.157
pknox1.2pbx/knotted 1 homeobox 1.20.152
smarcd1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.148
mlh1mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)0.146
prps1bphosphoribosyl pyrophosphate synthetase 1B0.145
nap1l1nucleosome assembly protein 1, like 10.145
ehmt2euchromatic histone-lysine N-methyltransferase 20.145
ets1av-ets erythroblastosis virus E26 oncogene homolog 1a0.144
sirt2sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)0.142
rrm1ribonucleotide reductase M1 polypeptide0.138
ptenaphosphatase and tensin homolog A0.136
xpcxeroderma pigmentosum, complementation group C0.134
gins2GINS complex subunit 20.132
zff9zinc finger protein 90.130
hat1histone acetyltransferase 10.130
ctbp1C-terminal binding protein 10.129
mycl1av-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) a0.129
smc2structural maintenance of chromosomes 20.128
mll4bmyeloid/lymphoid or mixed-lineage leukemia 4b0.126
melkmaternal embryonic leucine zipper kinase0.126
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.124
slc7a6ossolute carrier family 7, member 6 opposite strand0.123
ehmt1aeuchromatic histone-lysine N-methyltransferase 1a0.122
morf4l1mortality factor 4 like 10.122
hoxc9ahomeo box C9a0.122
setd2SET domain containing 20.121
orgoogenesis-related gene0.120
prdm2bPR domain containing 2, with ZNF domain b0.120
gle1GLE1 RNA export mediator homolog (yeast)0.118
whsc1Wolf-Hirschhorn syndrome candidate 10.117
chtf18CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)0.117
hoxa9ahomeo box A9a0.114
ccnd1cyclin D10.113
wdr76WD repeat domain 760.111
cbx5chromobox homolog 5 (HP1 alpha homolog, Drosophila)0.110
msh6mutS homolog 6 (E. coli)0.108
prkrirprotein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)0.103
sumo3aSMT3 suppressor of mif two 3 homolog 3a0.102
mcrs1microspherule protein 10.101
tal1T-cell acute lymphocytic leukemia 10.101
prmt5protein arginine methyltransferase 50.100
pak2bp21 (CDKN1A)-activated kinase 2b0.100
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
poloCG12306 gene product from transcript CG12306-RA1.000
aspabnormal spindle1.000
DrefDNA replication-related element factor1.000
Mcm10Sensitized chromosome inheritance modifier 190.999
mod(mdg4)modifier of mdg40.999
Sir2CG5216 gene product from transcript CG5216-RA0.998
Fs(2)KetFemale sterile (2) Ketel0.998
RfC4Replication factor C subunit 40.997
Rpd3CG7471 gene product from transcript CG7471-RA0.997
E(z)Enhancer of zeste0.995
IswiImitation SWI0.995
p53CG33336 gene product from transcript CG33336-RB0.994
ScmSex comb on midleg0.994
mus209mutagen-sensitive 2090.993
Su(var)2-HP2CG12864 gene product from transcript CG12864-RB0.993
BubR1Bub1-related kinase0.992
Cp190Centrosomal protein 190kD0.992
Rca1Regulator of cyclin A10.991
Su(var)2-10Suppressor of variegation 2-100.990
nbsCG6754 gene product from transcript CG6754-RC0.984
CycACyclin A0.983
Cenp-CCG31258 gene product from transcript CG31258-RA0.981
Su(var)205Suppressor of variegation 2050.980
Orc2Origin recognition complex subunit 20.979
pr-set7CG3307 gene product from transcript CG3307-RC0.977
CTCFCG8591 gene product from transcript CG8591-RA0.975
wocwithout children0.971
SMC2CG10212 gene product from transcript CG10212-RA0.969
SMC1CG6057 gene product from transcript CG6057-RA0.969
spn-Espindle E0.966
Snr1Snf5-related 10.963
Dhc64CDynein heavy chain 64C0.959
Hsp83Heat shock protein 830.958
CG3363CG3363 gene product from transcript CG3363-RB0.958
smt3CG4494 gene product from transcript CG4494-RA0.958
piepineapple eye0.956
CSN4COP9 complex homolog subunit 40.956
CG9772CG9772 gene product from transcript CG9772-RB0.950
RbfRetinoblastoma-family protein0.949
Ino80CG31212 gene product from transcript CG31212-RA0.947
Ndc80CG9938 gene product from transcript CG9938-RA0.945
IncenpInner centromere protein0.940
Chrac-14CG13399 gene product from transcript CG13399-RA0.938
Src64BSrc oncogene at 64B0.935
XNPCG4548 gene product from transcript CG4548-RA0.933
Klp61FKinesin-like protein at 61F0.924
RhebCG1081 gene product from transcript CG1081-RA0.924
Akt1CG4006 gene product from transcript CG4006-RA0.911
tefutelomere fusion0.908
slmbsupernumerary limbs0.897
Spc25CG7242 gene product from transcript CG7242-RA0.896
CycBCyclin B0.894
idaimaginal discs arrested0.889
spn-Bspindle B0.889
l(1)dd4lethal (1) discs degenerate 40.885
Caf1-180CG12109 gene product from transcript CG12109-RB0.883
Cap-GCG34438 gene product from transcript CG34438-RF0.876
Rae1CG9862 gene product from transcript CG9862-RA0.874
marsCG17064 gene product from transcript CG17064-RB0.873
HsfHeat shock factor0.867
dupdouble parked0.867
Nipped-ACG33554 gene product from transcript CG33554-RE0.867
Klp10ACG1453 gene product from transcript CG1453-RA0.865
Top2Topoisomerase 20.853
rad50CG6339 gene product from transcript CG6339-RD0.851
mei-41meiotic 410.851
AGO2Argonaute 20.840
SuURSuppressor of Under-Replication0.835
cicubitus interruptus0.834
Hsp68Heat shock protein 680.834
Su(var)3-3Suppressor of variegation 3-30.818
dpadisc proliferation abnormal0.817
CycECyclin E0.817
escextra sexcombs0.817
BRWD3CG31132 gene product from transcript CG31132-RA0.813
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Actbactin, beta0.233
Phf12PHD finger protein 120.226
Mcm7minichromosome maintenance complex component 70.223
Top2atopoisomerase (DNA) II alpha0.187
Ube2iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.163
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.142
Timelesstimeless homolog (Drosophila)0.140
Parp1poly (ADP-ribose) polymerase 10.112
Casp2caspase 20.110
Stip1stress-induced phosphoprotein 10.097
Bat1HLA-B associated transcript 10.094
Zfp91zinc finger protein 910.094
Dcaf15DDB1 and CUL4 associated factor 150.092
Dhx30DEAH (Asp-Glu-Ala-His) box polypeptide 300.086
Falzfetal Alzheimer antigen0.085
Mcm5minichromosome maintenance complex component 50.082
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.081
Lbrlamin B receptor0.079
Srrm2serine/arginine repetitive matrix 20.077
Klf9Kruppel-like factor 90.077
Foxm1forkhead box M10.076
Dlgap5discs, large (Drosophila) homolog-associated protein 50.075
Mybl2myeloblastosis oncogene-like 20.074
Traf4af1TRAF4 associated factor 10.070
Hspa8heat shock protein 80.070
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.070
Sf3b3splicing factor 3b, subunit 30.067
Trim28tripartite motif-containing 280.060
Ehmt2euchromatic histone lysine N-methyltransferase 20.059
Kif18bkinesin family member 18B0.057
Med1mediator complex subunit 10.057
Map2k7mitogen activated protein kinase kinase 70.057
Cct3chaperonin containing Tcp1, subunit 3 (gamma)0.055
Iqgap1IQ motif containing GTPase activating protein 10.053
Ccnb1cyclin B10.053
Kif22kinesin family member 220.052
Tpm3tropomyosin 3, gamma0.050
Eif4a1eukaryotic translation initiation factor 4A, isoform 10.048
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.048
Numa1nuclear mitotic apparatus protein 10.046
Prc1protein regulator of cytokinesis 10.044
Arih2ariadne homolog 2 (Drosophila)0.043
Pttg1pituitary tumor-transforming 10.043
Lsm14aLSM14A, SCD6 homolog A (S. cerevisiae)0.043
Itgb1integrin, beta 10.042
Ppm1gprotein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform0.042
Cggbp1CGG triplet repeat binding protein 10.041
Troaptrophinin associated protein0.040
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.039
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.039
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.039
Usp7ubiquitin specific peptidase 7 (herpes virus-associated)0.038
Cstf1cleavage stimulation factor, 3' pre-RNA, subunit 10.037
Racgap1Rac GTPase-activating protein 10.036
Tubb5tubulin, beta 50.036
Acin1apoptotic chromatin condensation inducer 10.035
Ppp2r2aprotein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform0.035
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.035
SetSET nuclear oncogene0.034
Cenptcentromere protein T0.034
Actr3ARP3 actin-related protein 3 homolog (yeast)0.034
Rbbp7retinoblastoma binding protein 70.033
Cdc42cell division cycle 42 (GTP binding protein)0.033
Uba1ubiquitin-like modifier activating enzyme 10.033
Arid4aAT rich interactive domain 4A (Rbp1 like)0.032
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.032
Bud13BUD13 homolog (S. cerevisiae)0.032
Ube2cubiquitin-conjugating enzyme E2C0.032
Supt16hsuppressor of Ty 16 homolog (S. cerevisiae)0.032
Ppp3cbprotein phosphatase 3, catalytic subunit, beta isoform0.031
Eef2eukaryotic translation elongation factor 20.031
Slc23a3solute carrier family 23 (nucleobase transporters), member 30.031
Nucks1nuclear casein kinase and cyclin-dependent kinase substrate 10.031
Axin1axin 10.031
Socs5suppressor of cytokine signaling 50.030
Rbm10RNA binding motif protein 100.030
Ufd1lubiquitin fusion degradation 1 like (yeast)0.030
Nup205nucleoporin 2050.030
Daxxdeath-domain associated protein0.030
Klhl7kelch-like 7 (Drosophila)0.030
Fkbp4FK506 binding protein 40.030
Pou2f2POU class 2 homeobox 20.030
Cd82Cd82 molecule0.030
Bbxbobby sox homolog (Drosophila)0.030
Hspd1heat shock protein 1 (chaperonin)0.030
Hnrnpabheterogeneous nuclear ribonucleoprotein A/B0.030
Mettl9methyltransferase like 90.029
Setd6SET domain containing 60.029
Wdr26WD repeat domain 260.029
Mcrs1microspherule protein 10.029
Hsph1heat shock 105/110 protein 10.028
Hnrnprheterogeneous nuclear ribonucleoprotein R0.028
Hspb1heat shock protein 10.028
Tnrc6btrinucleotide repeat containing 6B0.028
Cdk1cyclin-dependent kinase 10.028
Kif4kinesin family member 40.028
Sf3b2splicing factor 3b, subunit 20.028
Nsfl1cNSFL1 (p97) cofactor (p47)0.027
Asna1arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)0.027
Eif1ayeukaryotic translation initiation factor 1A, Y-linked0.027
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism