The network for 'regulation of protein kinase activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of protein kinase activity

Any process that modulates the frequency, rate or extent of protein kinase activity.

NameDescriptionProbabilityFunc Analog Organism
plc-1Protein PLC-10.100
vab-3Protein VAB-30.099
sur-2Protein SUR-20.076
mec-2Protein MEC-20.069
bar-1Protein BAR-10.059
tps-1Protein TPS-10.053
eps-8Protein EPS-80.053
pal-1Protein PAL-10.053
inx-3Protein INX-30.053
sax-7Protein SAX-70.048
pig-1Protein PIG-10.047
unc-7Protein UNC-70.046
K10D6.4Protein K10D6.40.045
egl-27Protein EGL-270.045
nhr-6Protein NHR-60.041
K08E3.5Protein K08E3.50.041
mbk-2Protein MBK-20.040
par-3Protein PAR-30.040
daf-6Protein DAF-60.038
apl-1Protein APL-10.036
mpk-1Protein MPK-10.035
sto-4Protein STO-40.034
glp-1Protein GLP-10.033
xpo-1Protein XPO-10.033
atg-2Protein ATG-20.033
plc-3Protein PLC-30.033
chd-7Protein CHD-70.032
inx-13Protein INX-130.032
let-756Protein LET-7560.031
daf-1Protein DAF-10.030
mek-2Protein MEK-20.030
abl-1Protein ABL-10.029
mef-2Protein MEF-20.029
nth-1Protein NTH-10.029
mes-3Protein MES-30.029
C53B4.4Protein C53B4.40.028
F07A11.2Protein F07A11.20.028
egl-8Protein EGL-80.028
arrd-25Protein ARRD-250.027
unc-53Protein UNC-530.027
cam-1Protein CAM-10.026
exc-5Protein EXC-50.026
mel-26Protein MEL-260.026
CELE_Y57A10A.8Protein Y57A10A.80.026
csnk-1Protein CSNK-10.025
mei-1Protein MEI-10.025
magi-1Protein MAGI-10.025
unc-9Protein UNC-90.025
ptr-2Protein PTR-20.025
sma-6Protein SMA-60.024
ceh-32Protein CEH-320.024
inx-4Protein INX-40.024
nlg-1Protein NLG-10.023
hmr-1Protein HMR-10.023
ida-1Protein IDA-10.023
let-60Protein LET-600.023
lin-36Protein LIN-360.023
C35D10.1Protein C35D10.10.023
dep-1Protein DEP-10.022
egl-36Protein EGL-360.022
R11A8.7Protein R11A8.70.022
unc-73Protein UNC-730.022
sek-1Protein SEK-10.022
hmg-1.2Protein HMG-1.20.021
pkn-1Protein PKN-10.021
C13F10.4Protein C13F10.40.021
sas-4Protein SAS-40.021
M01A8.2Protein M01A8.20.021
ZK507.6Protein ZK507.60.021
smp-1Protein SMP-10.021
eor-2Protein EOR-20.021
rskn-1Protein RSKN-10.020
T01G1.2Protein T01G1.20.020
kgb-1Protein KGB-10.020
pup-2Protein PUP-20.020
alg-1Protein ALG-10.019
mec-4Protein MEC-40.019
smf-3Protein SMF-30.019
sma-1Protein SMA-10.019
ztf-7Protein ZTF-70.019
svh-2Protein SVH-20.019
pry-1Protein PRY-10.019
C05D10.4Protein C05D10.40.018
olrn-1Protein OLRN-10.018
pat-12Protein PAT-120.018
camt-1Protein CAMT-10.018
lir-1Protein LIR-10.018
tax-6Protein TAX-60.018
F53B1.2Protein F53B1.20.018
hel-1Protein HEL-10.018
plk-1Protein PLK-10.017
zyg-11Protein ZYG-110.017
nhr-35Protein NHR-350.017
K10D6.2Protein K10D6.20.017
wwp-1Protein WWP-10.017
flr-4Protein FLR-40.017
T20D3.11Protein T20D3.110.017
unc-43Protein UNC-430.017
ftt-2Protein FTT-20.016
gpd-4Protein GPD-40.016
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
flhfloating head0.106
wnt1wingless-type MMTV integration site family, member 10.085
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.084
wnt2bbwingless-type MMTV integration site family, member 2Bb0.081
spry4sprouty (Drosophila) homolog 40.061
lcp1lymphocyte cytosolic plastin 10.049
gadd45bagrowth arrest and DNA-damage-inducible, beta a0.046
dusp6dual specificity phosphatase 60.045
rnd3aRho family GTPase 3a0.029
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.029
ccna2cyclin A20.027
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.026
zbtb4zinc finger and BTB domain containing 40.023
tlr3toll-like receptor 30.023
igf1rbinsulin-like growth factor 1b receptor0.023
socs3asuppressor of cytokine signaling 3a0.022
terttelomerase reverse transcriptase0.022
crip2cysteine-rich protein 20.022
ptprsaprotein tyrosine phosphatase, receptor type, s, a0.021
igf1rainsulin-like growth factor 1a receptor0.021
pou5f1POU domain, class 5, transcription factor 10.021
id1inhibitor of DNA binding 10.021
gadd45bbgrowth arrest and DNA-damage-inducible, beta b0.020
sall1asal-like 1a (Drosophila)0.020
sox11aSRY-box containing gene 11a0.020
rhoubras homolog gene family, member Ub0.020
eporerythropoietin receptor0.019
ighmimmunoglobulin heavy constant mu and immunoglobulin heavy constant mu0.018
igf1insulin-like growth factor 10.018
nod1nucleotide-binding oligomerization domain containing 10.018
psen1presenilin 10.018
krt18keratin 180.018
bnc2basonuclin 20.018
pak2ap21 (CDKN1A)-activated kinase 2a0.017
enc1ectodermal-neural cortex (with BTB-like domain)0.017
fgf3fibroblast growth factor 30.017
neo1neogenin 10.017
acvr2aactivin receptor IIa0.017
appaamyloid beta (A4) precursor protein a0.016
junjun proto-oncogene0.016
foxa2forkhead box A20.016
lama5laminin, alpha 50.016
dharmadharma0.016
rhoabras homolog gene family, member Ab0.016
spna2spectrin alpha 20.016
ccnb1cyclin B10.015
dag1dystroglycan 10.015
rarabretinoic acid receptor, alpha b0.015
ptenbphosphatase and tensin homolog B (mutated in multiple advanced cancers 1)0.015
smad7MAD, mothers against decapentaplegic homolog 7 (Drosophila)0.015
sox32SRY-box containing gene 320.014
dkk1bdickkopf 1b0.014
erbb3av-erb-b2 erythroblastic leukemia viral oncogene homolog 3a0.014
osr1odd-skipped related 1 (Drosophila)0.014
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.014
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.014
si:dkeyp-50f5.1si:dkeyp-50f5.10.014
tnfsf10ltumor necrosis factor (ligand) superfamily, member 10 like0.014
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.014
hspa4aheat shock protein 4a0.013
mapk1mitogen-activated protein kinase 10.013
fasFas (TNF receptor superfamily, member 6)0.013
tcf12transcription factor 120.013
card9caspase recruitment domain family, member 90.013
wnt10awingless-type MMTV integration site family, member 10a0.013
mbtps1membrane-bound transcription factor protease, site 10.013
pcsk5bproprotein convertase subtilisin/kexin type 5b0.013
atp2b4ATPase, Ca++ transporting, plasma membrane 40.013
prkaa1protein kinase, AMP-activated, alpha 1 catalytic subunit0.013
oepone-eyed pinhead0.013
wu:fb58e05wu:fb58e050.013
mapk14amitogen-activated protein kinase 14a0.013
col7a1lcollagen type VII alpha 1-like0.013
gnb1aguanine nucleotide binding protein (G protein), beta polypeptide 1a0.013
junbjun B proto-oncogene0.012
ptpraprotein tyrosine phosphatase, receptor type, A0.012
aox3aldehyde oxidase 30.012
fzd7afrizzled homolog 7a0.012
LOC100151531zinc finger protein Gfi-1b-like0.012
ntrk2bneurotrophic tyrosine kinase, receptor, type 2b0.012
vedventrally expressed dharma/bozozok antagonist0.012
tagln2transgelin 20.012
mycbp2MYC binding protein 20.012
gli3GLI-Kruppel family member GLI30.012
si:ch211-57k11.10si:ch211-57k11.100.012
h3f3aH3 histone, family 3A0.012
dip2cDIP2 disco-interacting protein 2 homolog C (Drosophila)0.012
sox11bSRY-box containing gene 11b0.012
nr2e3nuclear receptor subfamily 2, group E, member 30.012
ighzimmunoglobulin heavy constant zeta0.012
nfe2l2nuclear factor (erythroid-derived 2)-like 20.012
arl4abADP-ribosylation factor-like 4ab0.012
epas1bendothelial PAS domain protein 1b0.012
socs1suppressor of cytokine signaling 10.012
grin1aglutamate receptor, ionotropic, N-methyl D-aspartate 1a0.012
wnt5bwingless-type MMTV integration site family, member 5b0.012
mpped2metallophosphoesterase domain containing 20.012
htra1aHtrA serine peptidase 1a0.012
junbljun B proto-oncogene, like0.011
wnt10bwingless-type MMTV integration site family, member 10b0.011
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Ras85DRas oncogene at 85D0.998
rlrolled0.982
G-oalpha47AG protein oalpha 47A0.970
Pi3K92ECG4141 gene product from transcript CG4141-RB0.939
drkdownstream of receptor kinase0.914
Akt1CG4006 gene product from transcript CG4006-RA0.908
MadMothers against dpp0.866
CkIIalphaCasein kinase II alpha subunit0.837
kaykayak0.738
InRInsulin-like receptor0.713
Rho1CG8416 gene product from transcript CG8416-RB0.670
par-1CG8201 gene product from transcript CG8201-RA0.662
Atg1Autophagy-specific gene 10.652
chicoCG5686 gene product from transcript CG5686-RB0.586
DabDisabled0.579
ttktramtrack0.569
bskbasket0.544
CycECyclin E0.528
shnschnurri0.512
Stat92ESignal-transducer and activator of transcription protein at 92E0.486
enaenabled0.483
dshdishevelled0.476
Sin3ACG8815 gene product from transcript CG8815-RC0.421
pucpuckered0.415
G-salpha60AG protein salpha 60A0.413
phlpole hole0.411
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.405
SaraSmad anchor for receptor activation0.398
Rab11Rab-protein 110.379
Rac1CG2248 gene product from transcript CG2248-RA0.377
Rab5Rab-protein 50.371
PknProtein kinase related to protein kinase N0.352
scbscab0.345
DadDaughters against dpp0.334
bazbazooka0.331
rutrutabaga0.331
Src42ASrc oncogene at 42A0.326
dapdacapo0.324
cazcabeza0.322
shishibire0.310
CG5794CG5794 gene product from transcript CG5794-RB0.305
CaMKIICalcium/calmodulin-dependent protein kinase II0.302
ctaconcertina0.302
nejnejire0.299
jebjelly belly0.271
X11LCG5675 gene product from transcript CG5675-RB0.251
aopanterior open0.246
JraJun-related antigen0.239
HLHmdeltaE(spl) region transcript mdelta0.236
babobaboon0.232
Fmr1CG6203 gene product from transcript CG6203-RC0.232
p38bCG7393 gene product from transcript CG7393-RA0.220
krzkurtz0.218
HLHm7E(spl) region transcript m70.215
Cdc42CG12530 gene product from transcript CG12530-RA0.214
NFATNFAT homolog0.210
Socs36ESuppressor of cytokine signaling at 36E0.209
zfh1Zn finger homeodomain 10.205
CG13253CG13253 gene product from transcript CG13253-RB0.204
Cip4CG15015 gene product from transcript CG15015-RA0.200
twstwins0.200
sggshaggy0.180
Su(H)Suppressor of Hairless0.176
ovoCG6824 gene product from transcript CG6824-RE0.169
stcksteamer duck0.164
EndoGIEndonuclease G inhibitor0.160
Ptp69DProtein tyrosine phosphatase 69D0.157
p53CG33336 gene product from transcript CG33336-RB0.157
TspThrombospondin0.156
hipkhomeodomain interacting protein kinase0.154
TlToll0.153
pnutpeanut0.151
EgfrEpidermal growth factor receptor0.150
mewmultiple edematous wings0.149
numbCG3779 gene product from transcript CG3779-RB0.148
Pk61CProtein kinase 61C0.147
Dhc64CDynein heavy chain 64C0.145
HLHmgammaE(spl) region transcript mgamma0.143
sevsevenless0.140
Tao-1CG14217 gene product from transcript CG14217-RF0.132
CycACyclin A0.129
Ras64BRas oncogene at 64B0.127
drongoCG3365 gene product from transcript CG3365-RH0.125
Mob2CG11711 gene product from transcript CG11711-RC0.122
Tsc1CG6147 gene product from transcript CG6147-RA0.121
foxoforkhead box, sub-group O0.121
pumpumilio0.121
CakiCalcium/calmodulin-dependent protein kinase0.120
trioCG18214 gene product from transcript CG18214-RA0.120
Cdk4Cyclin-dependent kinase 40.119
StimStromal interaction molecule0.119
diadiaphanous0.118
dosdaughter of sevenless0.117
dncdunce0.116
E(spl)Enhancer of split0.115
Hs6stHeparan sulfate 6-O-sulfotransferase0.112
dallydivision abnormally delayed0.112
spasspastin0.110
Mpk2CG5475 gene product from transcript CG5475-RB0.106
giggigas0.105
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor1.000
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence1.000
ABL1c-abl oncogene 1, non-receptor tyrosine kinase1.000
RB1retinoblastoma 11.000
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.999
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.999
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.998
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.998
UBCubiquitin C0.998
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.997
MAP3K7mitogen-activated protein kinase kinase kinase 70.995
TRAF6TNF receptor-associated factor 60.995
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.995
AKT1v-akt murine thymoma viral oncogene homolog 10.994
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.993
PLCG1phospholipase C, gamma 10.993
MAPK14mitogen-activated protein kinase 140.993
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.993
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.993
MAPK8mitogen-activated protein kinase 80.990
JUNjun proto-oncogene0.987
MAPK1mitogen-activated protein kinase 10.986
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.983
DUSP1dual specificity phosphatase 10.981
METmet proto-oncogene (hepatocyte growth factor receptor)0.979
MAP3K5mitogen-activated protein kinase kinase kinase 50.973
GRB2growth factor receptor-bound protein 20.971
SNX9sorting nexin 90.971
IRAK2interleukin-1 receptor-associated kinase 20.958
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.950
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.949
CCND1cyclin D10.948
FYNFYN oncogene related to SRC, FGR, YES0.941
PTPN1protein tyrosine phosphatase, non-receptor type 10.939
ARRB1arrestin, beta 10.939
PTPN11protein tyrosine phosphatase, non-receptor type 110.938
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.935
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.932
SQSTM1sequestosome 10.931
PRKCZprotein kinase C, zeta0.931
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 10.931
TAB2TGF-beta activated kinase 1/MAP3K7 binding protein 20.930
BBS10Bardet-Biedl syndrome 100.928
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.926
MAP3K3mitogen-activated protein kinase kinase kinase 30.923
VAV1vav 1 guanine nucleotide exchange factor0.923
SHC1SHC (Src homology 2 domain containing) transforming protein 10.922
LCKlymphocyte-specific protein tyrosine kinase0.920
TP53tumor protein p530.917
IGF1Rinsulin-like growth factor 1 receptor0.917
FGFR2fibroblast growth factor receptor 20.915
LRRK2leucine-rich repeat kinase 20.907
CDC37cell division cycle 37 homolog (S. cerevisiae)0.906
TOLLIPtoll interacting protein0.900
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.889
ADAM15ADAM metallopeptidase domain 150.887
MDM2Mdm2 p53 binding protein homolog (mouse)0.886
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.885
SMAD3SMAD family member 30.883
SH3KBP1SH3-domain kinase binding protein 10.881
FGFR1fibroblast growth factor receptor 10.876
ESR1estrogen receptor 10.875
SMAD2SMAD family member 20.872
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.864
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.846
CSNK1Ecasein kinase 1, epsilon0.825
CCND3cyclin D30.822
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.816
GAB1GRB2-associated binding protein 10.808
FOSFBJ murine osteosarcoma viral oncogene homolog0.807
PTK2PTK2 protein tyrosine kinase 20.806
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 10.806
CDK6cyclin-dependent kinase 60.804
MAP3K11mitogen-activated protein kinase kinase kinase 110.801
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.791
JUNBjun B proto-oncogene0.786
CCNE1cyclin E10.784
PTK2BPTK2B protein tyrosine kinase 2 beta0.772
BTRCbeta-transducin repeat containing0.769
MAP2K4mitogen-activated protein kinase kinase 40.763
CAV1caveolin 1, caveolae protein, 22kDa0.758
CEACAM1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)0.746
CDK9cyclin-dependent kinase 90.742
C1QAcomplement component 1, q subcomponent, A chain0.729
MAP2K7mitogen-activated protein kinase kinase 70.728
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.727
FLNBfilamin B, beta0.727
DLG1discs, large homolog 1 (Drosophila)0.726
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.723
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.717
MAP2K1mitogen-activated protein kinase kinase 10.717
TSC2tuberous sclerosis 20.713
CREBBPCREB binding protein0.711
CDK2cyclin-dependent kinase 20.706
CALM1calmodulin 1 (phosphorylase kinase, delta)0.705
TAB1TGF-beta activated kinase 1/MAP3K7 binding protein 10.705
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.698
MUC1mucin 1, cell surface associated0.687
CEACAM6carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)0.685
CDC27cell division cycle 27 homolog (S. cerevisiae)0.683
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ctnnb1catenin (cadherin associated protein), beta 11.000
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)1.000
CblCasitas B-lineage lymphoma0.998
Trp53transformation related protein 530.998
Leprleptin receptor0.998
Ptenphosphatase and tensin homolog0.997
Apcadenomatosis polyposis coli0.997
Ptpn11protein tyrosine phosphatase, non-receptor type 110.997
Efnb2ephrin B20.993
Nr3c1nuclear receptor subfamily 3, group C, member 10.989
Socs1suppressor of cytokine signaling 10.988
Grb2growth factor receptor bound protein 20.988
Map3k7mitogen-activated protein kinase kinase kinase 70.986
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.985
Mapk8mitogen-activated protein kinase 80.982
Gli3GLI-Kruppel family member GLI30.982
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.980
Dab1disabled homolog 1 (Drosophila)0.979
Egfrepidermal growth factor receptor0.978
SrcRous sarcoma oncogene0.978
Rb1retinoblastoma 10.977
Ephb2Eph receptor B20.975
Cd44CD44 antigen0.970
Itgb1integrin beta 1 (fibronectin receptor beta)0.964
Tnftumor necrosis factor0.961
Rac1RAS-related C3 botulinum substrate 10.961
Ptgs2prostaglandin-endoperoxide synthase 20.959
Tnfaip3tumor necrosis factor, alpha-induced protein 30.956
Dok1docking protein 10.956
Mdm2transformed mouse 3T3 cell double minute 20.951
Smad3MAD homolog 3 (Drosophila)0.950
Vangl2vang-like 2 (van gogh, Drosophila)0.939
Fgfr2fibroblast growth factor receptor 20.937
Lyz2lysozyme 20.934
FosFBJ osteosarcoma oncogene0.934
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.932
Yap1yes-associated protein 10.931
Plcg1phospholipase C, gamma 10.929
Axin1axin 10.925
Cdkn2acyclin-dependent kinase inhibitor 2A0.920
Cdkn1bcyclin-dependent kinase inhibitor 1B0.914
Gsk3bglycogen synthase kinase 3 beta0.914
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.912
Thbs1thrombospondin 10.900
Flt1FMS-like tyrosine kinase 10.898
JunJun oncogene0.896
Inpp5dinositol polyphosphate-5-phosphatase D0.895
Tgfb2transforming growth factor, beta 20.890
Appamyloid beta (A4) precursor protein0.889
Il1r1interleukin 1 receptor, type I0.885
Cdkn2ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)0.883
Ccnd1cyclin D10.876
Esr1estrogen receptor 1 (alpha)0.863
Tsc1tuberous sclerosis 10.858
Nos1nitric oxide synthase 1, neuronal0.855
Retret proto-oncogene0.852
Mapk14mitogen-activated protein kinase 140.833
Tgfbr1transforming growth factor, beta receptor I0.833
Trp63transformation related protein 630.833
AxlAXL receptor tyrosine kinase0.832
Traf6TNF receptor-associated factor 60.828
Irs1insulin receptor substrate 10.824
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.810
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.807
Csf1colony stimulating factor 1 (macrophage)0.805
FynFyn proto-oncogene0.805
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.803
Stat3signal transducer and activator of transcription 30.802
Ednrbendothelin receptor type B0.791
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.788
Fzd4frizzled homolog 4 (Drosophila)0.785
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.780
Insrinsulin receptor0.770
Arrb2arrestin, beta 20.763
Fbn1fibrillin 10.752
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.751
BrafBraf transforming gene0.747
Epas1endothelial PAS domain protein 10.744
Lrp1low density lipoprotein receptor-related protein 10.743
Stk4serine/threonine kinase 40.742
Tgfatransforming growth factor alpha0.736
Il6stinterleukin 6 signal transducer0.731
Efnb1ephrin B10.727
Ptk7PTK7 protein tyrosine kinase 70.722
Klf7Kruppel-like factor 7 (ubiquitous)0.716
Nck2non-catalytic region of tyrosine kinase adaptor protein 20.712
Prkceprotein kinase C, epsilon0.710
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.705
C3ar1complement component 3a receptor 10.705
Bmpr1abone morphogenetic protein receptor, type 1A0.703
Dvl3dishevelled 3, dsh homolog (Drosophila)0.702
Nf1neurofibromatosis 10.700
Adam12a disintegrin and metallopeptidase domain 12 (meltrin alpha)0.699
Gab1growth factor receptor bound protein 2-associated protein 10.698
Ptk2PTK2 protein tyrosine kinase 20.696
RictorRPTOR independent companion of MTOR, complex 20.694
Trp73transformation related protein 730.687
Ccr1chemokine (C-C motif) receptor 10.686
Il1binterleukin 1 beta0.682
Tspan9tetraspanin 90.680
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Dusp1dual specificity phosphatase 10.598
Sirpasignal-regulatory protein alpha0.596
Jak2Janus kinase 20.575
JunJun oncogene0.509
Inpp5dinositol polyphosphate-5-phosphatase D0.366
Grb2growth factor receptor bound protein 20.315
Klf6Kruppel-like factor 60.301
Mr1major histocompatibility complex, class I-related0.288
Btg2BTG family, member 20.280
Mapk9mitogen-activated protein kinase 90.261
Junbjun B proto-oncogene0.258
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.255
Vav1vav 1 guanine nucleotide exchange factor0.239
Nrp1neuropilin 10.222
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.220
Agtr1aangiotensin II receptor, type 1a0.214
Kcnj4potassium inwardly-rectifying channel, subfamily J, member 40.210
Prkcdprotein kinase C, delta0.208
Zfp36zinc finger protein 360.203
Cdh17cadherin 170.201
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.200
Egfrepidermal growth factor receptor0.197
Fosl1fos-like antigen 10.196
Errfi1ERBB receptor feedback inhibitor 10.191
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.180
Cd38CD38 molecule0.179
Mapk1mitogen activated protein kinase 10.176
Bcanbrevican0.176
Prdm2PR domain containing 2, with ZNF domain0.175
Cmklr1chemokine-like receptor 10.168
Mapk3mitogen activated protein kinase 30.167
Nek9NIMA (never in mitosis gene a)- related kinase 90.162
FosFBJ osteosarcoma oncogene0.155
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.152
Vom2r53vomeronasal 2 receptor, 530.152
Grm7glutamate receptor, metabotropic 70.151
Myo1emyosin IE0.150
Drd2dopamine receptor D20.149
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.148
Hpcahippocalcin0.148
Slc7a12solute carrier family 7 (cationic amino acid transporter, y+ system), member 120.148
Homer3homer homolog 3 (Drosophila)0.147
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.146
Tas2r107taste receptor, type 2, member 1070.145
Clstn3calsyntenin 30.145
NsfN-ethylmaleimide-sensitive factor0.143
Metmet proto-oncogene0.137
Mpeg1macrophage expressed 10.137
Gna12guanine nucleotide binding protein (G protein) alpha 120.136
Adrbk1adrenergic, beta, receptor kinase 10.133
Cdc42cell division cycle 42 (GTP binding protein)0.132
Nr4a1nuclear receptor subfamily 4, group A, member 10.132
Cx3cr1chemokine (C-X3-C motif) receptor 10.132
Pnlippancreatic lipase0.132
Slc6a6solute carrier family 6 (neurotransmitter transporter, taurine), member 60.131
Trhrthyrotropin releasing hormone receptor0.130
Unc5bunc-5 homolog B (C. elegans)0.129
Ier2immediate early response 20.128
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.128
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.128
Ptpn7protein tyrosine phosphatase, non-receptor type 70.127
Wdr26WD repeat domain 260.127
RGD1564664similar to LOC387763 protein0.124
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.124
Slco2a1solute carrier organic anion transporter family, member 2a10.123
Cfpcomplement factor properdin0.120
Fgfr1Fibroblast growth factor receptor 10.118
Akt1v-akt murine thymoma viral oncogene homolog 10.118
Pctk2PCTAIRE protein kinase 20.118
Stip1stress-induced phosphoprotein 10.117
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.117
Map6microtubule-associated protein 60.117
Smad3SMAD family member 30.116
Myo1bmyosin Ib0.116
Cd4Cd4 molecule0.115
Irs1insulin receptor substrate 10.115
Bdkrb2bradykinin receptor B20.114
Hk1hexokinase 10.112
Egr1early growth response 10.112
Prkchprotein kinase C, eta0.111
Necab1N-terminal EF-hand calcium binding protein 10.111
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.111
Ptpn6protein tyrosine phosphatase, non-receptor type 60.110
Prkacbprotein kinase, cAMP dependent, catalytic, beta0.110
Jak1Janus kinase 10.109
Ptprqprotein tyrosine phosphatase, receptor type, Q0.109
Utrnutrophin0.109
Pcnxl3pecanex-like 3 (Drosophila)0.109
Ptafrplatelet-activating factor receptor0.108
Hpcal4hippocalcin-like 40.107
Tle4transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)0.107
Adora2aadenosine A2a receptor0.107
Dusp6dual specificity phosphatase 60.106
Scarb1scavenger receptor class B, member 10.105
Ccnd1cyclin D10.105
Nedd4neural precursor cell expressed, developmentally down-regulated 40.104
Calcrlcalcitonin receptor-like0.103
Slc9a1solute carrier family 9 (sodium/hydrogen exchanger), member 10.103
Atf3activating transcription factor 30.103
Fgfr2fibroblast growth factor receptor 20.102
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
PBS2Pbs2p0.993
PIL1Pil1p0.977
BCK1Bck1p0.958
SSK2Ssk2p0.956
CLB3Clb3p0.926
CKS1Cks1p0.924
CLN1Cln1p0.921
BOI1Boi1p0.900
SHO1Sho1p0.887
NBP2Nbp2p0.883
ROM2Rom2p0.876
CDC28Cdc28p0.841
HSL1Hsl1p0.826
CDC12Cdc12p0.771
CLN2Cln2p0.766
SLT2Slt2p0.717
SWE1Swe1p0.693
DBF2Dbf2p0.668
HOG1Hog1p0.656
NAP1Nap1p0.646
PHO85Pho85p0.635
GIN4Gin4p0.560
BMH1Bmh1p0.544
CLB6Clb6p0.543
MSG5Msg5p0.529
CLB2Clb2p0.522
SIC1Sic1p0.513
SSK1Ssk1p0.504
STE20Ste20p0.481
STE7Ste7p0.467
PAM1Pam1p0.444
CAK1Cak1p0.443
FAR1Far1p0.411
SNF1Snf1p0.384
SIP1Sip1p0.340
GAL83Gal83p0.335
TOR1Tor1p0.328
BCK2Bck2p0.291
PPH21Pph21p0.289
FUS3Fus3p0.283
MKK1Mkk1p0.281
PTC1Ptc1p0.276
RAD53Rad53p0.273
PHO81Pho81p0.256
CLA4Cla4p0.256
CDC37Cdc37p0.243
SNF4Snf4p0.243
RPP1BRpp1bp0.236
EDE1Ede1p0.230
PCL9Pcl9p0.219
PCL10Pcl10p0.217
SIL1Sil1p0.217
CDC6Cdc6p0.206
SAK1Sak1p0.203
PCL1Pcl1p0.195
MKK2Mkk2p0.189
CDC10Cdc10p0.185
SSK22Ssk22p0.183
MKS1Mks1p0.181
ERO1Ero1p0.175
DIA2Dia2p0.174
ELP2Elp2p0.165
STE4Ste4p0.149
BFR1Bfr1p0.139
ATG21Atg21p0.135
BEM2Bem2p0.130
CDC11Cdc11p0.129
YPD1Ypd1p0.129
SIP2Sip2p0.124
CRZ1Crz1p0.122
CLB5Clb5p0.118
YPL014Whypothetical protein0.117
DIG1Dig1p0.116
GSY1Gsy1p0.114
LHS1Lhs1p0.113
ZDS1Zds1p0.112
HKR1Hkr1p0.111
CDC34Cdc34p0.110
CDH1Cdh1p0.110
HRR25Hrr25p0.109
CLB1Clb1p0.101
SLK19Slk19p0.100
TOR2Tor2p0.097
RPS29BRps29bp0.093
CDC55Cdc55p0.092
RLM1Rlm1p0.091
KCC4Kcc4p0.091
TRA1Tra1p0.091
ELP3Elp3p0.089
CLB4Clb4p0.088
SPC29Spc29p0.087
JEM1Jem1p0.087
CCW12Ccw12p0.086
HIR1Hir1p0.083
RRD1Rrd1p0.082
AXL2Axl2p0.081
PTK2Ptk2p0.079
PCL2Pcl2p0.079
RPN14Rpn14p0.079
RPP0Rpp0p0.078