IMP: Integrative Multi-species Prediction

The network for 'regulation of protein kinase activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of protein kinase activity

Any process that modulates the frequency, rate or extent of protein kinase activity.

Caenorhabditis elegans

Name	Description	Probability
plc-1	Protein PLC-1	0.100
vab-3	Protein VAB-3	0.099
sur-2	Protein SUR-2	0.076
mec-2	Protein MEC-2	0.069
bar-1	Protein BAR-1	0.059
tps-1	Protein TPS-1	0.053
eps-8	Protein EPS-8	0.053
pal-1	Protein PAL-1	0.053
inx-3	Protein INX-3	0.053
sax-7	Protein SAX-7	0.048
pig-1	Protein PIG-1	0.047
unc-7	Protein UNC-7	0.046
K10D6.4	Protein K10D6.4	0.045
egl-27	Protein EGL-27	0.045
nhr-6	Protein NHR-6	0.041
K08E3.5	Protein K08E3.5	0.041
mbk-2	Protein MBK-2	0.040
par-3	Protein PAR-3	0.040
daf-6	Protein DAF-6	0.038
apl-1	Protein APL-1	0.036
mpk-1	Protein MPK-1	0.035
sto-4	Protein STO-4	0.034
glp-1	Protein GLP-1	0.033
xpo-1	Protein XPO-1	0.033
atg-2	Protein ATG-2	0.033
plc-3	Protein PLC-3	0.033
chd-7	Protein CHD-7	0.032
inx-13	Protein INX-13	0.032
let-756	Protein LET-756	0.031
daf-1	Protein DAF-1	0.030
mek-2	Protein MEK-2	0.030
abl-1	Protein ABL-1	0.029
mef-2	Protein MEF-2	0.029
nth-1	Protein NTH-1	0.029
mes-3	Protein MES-3	0.029
C53B4.4	Protein C53B4.4	0.028
F07A11.2	Protein F07A11.2	0.028
egl-8	Protein EGL-8	0.028
arrd-25	Protein ARRD-25	0.027
unc-53	Protein UNC-53	0.027
cam-1	Protein CAM-1	0.026
exc-5	Protein EXC-5	0.026
mel-26	Protein MEL-26	0.026
CELE_Y57A10A.8	Protein Y57A10A.8	0.026
csnk-1	Protein CSNK-1	0.025
mei-1	Protein MEI-1	0.025
magi-1	Protein MAGI-1	0.025
unc-9	Protein UNC-9	0.025
ptr-2	Protein PTR-2	0.025
sma-6	Protein SMA-6	0.024
ceh-32	Protein CEH-32	0.024
inx-4	Protein INX-4	0.024
nlg-1	Protein NLG-1	0.023
hmr-1	Protein HMR-1	0.023
ida-1	Protein IDA-1	0.023
let-60	Protein LET-60	0.023
lin-36	Protein LIN-36	0.023
C35D10.1	Protein C35D10.1	0.023
dep-1	Protein DEP-1	0.022
egl-36	Protein EGL-36	0.022
R11A8.7	Protein R11A8.7	0.022
unc-73	Protein UNC-73	0.022
sek-1	Protein SEK-1	0.022
hmg-1.2	Protein HMG-1.2	0.021
pkn-1	Protein PKN-1	0.021
C13F10.4	Protein C13F10.4	0.021
sas-4	Protein SAS-4	0.021
M01A8.2	Protein M01A8.2	0.021
ZK507.6	Protein ZK507.6	0.021
smp-1	Protein SMP-1	0.021
eor-2	Protein EOR-2	0.021
rskn-1	Protein RSKN-1	0.020
T01G1.2	Protein T01G1.2	0.020
kgb-1	Protein KGB-1	0.020
pup-2	Protein PUP-2	0.020
alg-1	Protein ALG-1	0.019
mec-4	Protein MEC-4	0.019
smf-3	Protein SMF-3	0.019
sma-1	Protein SMA-1	0.019
ztf-7	Protein ZTF-7	0.019
svh-2	Protein SVH-2	0.019
pry-1	Protein PRY-1	0.019
C05D10.4	Protein C05D10.4	0.018
olrn-1	Protein OLRN-1	0.018
pat-12	Protein PAT-12	0.018
camt-1	Protein CAMT-1	0.018
lir-1	Protein LIR-1	0.018
tax-6	Protein TAX-6	0.018
F53B1.2	Protein F53B1.2	0.018
hel-1	Protein HEL-1	0.018
plk-1	Protein PLK-1	0.017
zyg-11	Protein ZYG-11	0.017
nhr-35	Protein NHR-35	0.017
K10D6.2	Protein K10D6.2	0.017
wwp-1	Protein WWP-1	0.017
flr-4	Protein FLR-4	0.017
T20D3.11	Protein T20D3.11	0.017
unc-43	Protein UNC-43	0.017
ftt-2	Protein FTT-2	0.016
gpd-4	Protein GPD-4	0.016

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Danio rerio

Name	Description	Probability
flh	floating head	0.106
wnt1	wingless-type MMTV integration site family, member 1	0.085
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.084
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.081
spry4	sprouty (Drosophila) homolog 4	0.061
lcp1	lymphocyte cytosolic plastin 1	0.049
gadd45ba	growth arrest and DNA-damage-inducible, beta a	0.046
dusp6	dual specificity phosphatase 6	0.045
rnd3a	Rho family GTPase 3a	0.029
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.029
ccna2	cyclin A2	0.027
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.026
zbtb4	zinc finger and BTB domain containing 4	0.023
tlr3	toll-like receptor 3	0.023
igf1rb	insulin-like growth factor 1b receptor	0.023
socs3a	suppressor of cytokine signaling 3a	0.022
tert	telomerase reverse transcriptase	0.022
crip2	cysteine-rich protein 2	0.022
ptprsa	protein tyrosine phosphatase, receptor type, s, a	0.021
igf1ra	insulin-like growth factor 1a receptor	0.021
pou5f1	POU domain, class 5, transcription factor 1	0.021
id1	inhibitor of DNA binding 1	0.021
gadd45bb	growth arrest and DNA-damage-inducible, beta b	0.020
sall1a	sal-like 1a (Drosophila)	0.020
sox11a	SRY-box containing gene 11a	0.020
rhoub	ras homolog gene family, member Ub	0.020
epor	erythropoietin receptor	0.019
ighm	immunoglobulin heavy constant mu and immunoglobulin heavy constant mu	0.018
igf1	insulin-like growth factor 1	0.018
nod1	nucleotide-binding oligomerization domain containing 1	0.018
psen1	presenilin 1	0.018
krt18	keratin 18	0.018
bnc2	basonuclin 2	0.018
pak2a	p21 (CDKN1A)-activated kinase 2a	0.017
enc1	ectodermal-neural cortex (with BTB-like domain)	0.017
fgf3	fibroblast growth factor 3	0.017
neo1	neogenin 1	0.017
acvr2a	activin receptor IIa	0.017
appa	amyloid beta (A4) precursor protein a	0.016
jun	jun proto-oncogene	0.016
foxa2	forkhead box A2	0.016
lama5	laminin, alpha 5	0.016
dharma	dharma	0.016
rhoab	ras homolog gene family, member Ab	0.016
spna2	spectrin alpha 2	0.016
ccnb1	cyclin B1	0.015
dag1	dystroglycan 1	0.015
rarab	retinoic acid receptor, alpha b	0.015
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.015
smad7	MAD, mothers against decapentaplegic homolog 7 (Drosophila)	0.015
sox32	SRY-box containing gene 32	0.014
dkk1b	dickkopf 1b	0.014
erbb3a	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a	0.014
osr1	odd-skipped related 1 (Drosophila)	0.014
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.014
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.014
si:dkeyp-50f5.1	si:dkeyp-50f5.1	0.014
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.014
kdr	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.014
hspa4a	heat shock protein 4a	0.013
mapk1	mitogen-activated protein kinase 1	0.013
fas	Fas (TNF receptor superfamily, member 6)	0.013
tcf12	transcription factor 12	0.013
card9	caspase recruitment domain family, member 9	0.013
wnt10a	wingless-type MMTV integration site family, member 10a	0.013
mbtps1	membrane-bound transcription factor protease, site 1	0.013
pcsk5b	proprotein convertase subtilisin/kexin type 5b	0.013
atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.013
prkaa1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.013
oep	one-eyed pinhead	0.013
wu:fb58e05	wu:fb58e05	0.013
mapk14a	mitogen-activated protein kinase 14a	0.013
col7a1l	collagen type VII alpha 1-like	0.013
gnb1a	guanine nucleotide binding protein (G protein), beta polypeptide 1a	0.013
junb	jun B proto-oncogene	0.012
ptpra	protein tyrosine phosphatase, receptor type, A	0.012
aox3	aldehyde oxidase 3	0.012
fzd7a	frizzled homolog 7a	0.012
LOC100151531	zinc finger protein Gfi-1b-like	0.012
ntrk2b	neurotrophic tyrosine kinase, receptor, type 2b	0.012
ved	ventrally expressed dharma/bozozok antagonist	0.012
tagln2	transgelin 2	0.012
mycbp2	MYC binding protein 2	0.012
gli3	GLI-Kruppel family member GLI3	0.012
si:ch211-57k11.10	si:ch211-57k11.10	0.012
h3f3a	H3 histone, family 3A	0.012
dip2c	DIP2 disco-interacting protein 2 homolog C (Drosophila)	0.012
sox11b	SRY-box containing gene 11b	0.012
nr2e3	nuclear receptor subfamily 2, group E, member 3	0.012
ighz	immunoglobulin heavy constant zeta	0.012
nfe2l2	nuclear factor (erythroid-derived 2)-like 2	0.012
arl4ab	ADP-ribosylation factor-like 4ab	0.012
epas1b	endothelial PAS domain protein 1b	0.012
socs1	suppressor of cytokine signaling 1	0.012
grin1a	glutamate receptor, ionotropic, N-methyl D-aspartate 1a	0.012
wnt5b	wingless-type MMTV integration site family, member 5b	0.012
mpped2	metallophosphoesterase domain containing 2	0.012
htra1a	HtrA serine peptidase 1a	0.012
junbl	jun B proto-oncogene, like	0.011
wnt10b	wingless-type MMTV integration site family, member 10b	0.011

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Drosophila melanogaster

Name	Description	Probability
Ras85D	Ras oncogene at 85D	0.998
rl	rolled	0.982
G-oalpha47A	G protein oalpha 47A	0.970
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.939
drk	downstream of receptor kinase	0.914
Akt1	CG4006 gene product from transcript CG4006-RA	0.908
Mad	Mothers against dpp	0.866
CkIIalpha	Casein kinase II alpha subunit	0.837
kay	kayak	0.738
InR	Insulin-like receptor	0.713
Rho1	CG8416 gene product from transcript CG8416-RB	0.670
par-1	CG8201 gene product from transcript CG8201-RA	0.662
Atg1	Autophagy-specific gene 1	0.652
chico	CG5686 gene product from transcript CG5686-RB	0.586
Dab	Disabled	0.579
ttk	tramtrack	0.569
bsk	basket	0.544
CycE	Cyclin E	0.528
shn	schnurri	0.512
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.486
ena	enabled	0.483
dsh	dishevelled	0.476
Sin3A	CG8815 gene product from transcript CG8815-RC	0.421
puc	puckered	0.415
G-salpha60A	G protein salpha 60A	0.413
phl	pole hole	0.411
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.405
Sara	Smad anchor for receptor activation	0.398
Rab11	Rab-protein 11	0.379
Rac1	CG2248 gene product from transcript CG2248-RA	0.377
Rab5	Rab-protein 5	0.371
Pkn	Protein kinase related to protein kinase N	0.352
scb	scab	0.345
Dad	Daughters against dpp	0.334
baz	bazooka	0.331
rut	rutabaga	0.331
Src42A	Src oncogene at 42A	0.326
dap	dacapo	0.324
caz	cabeza	0.322
shi	shibire	0.310
CG5794	CG5794 gene product from transcript CG5794-RB	0.305
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.302
cta	concertina	0.302
nej	nejire	0.299
jeb	jelly belly	0.271
X11L	CG5675 gene product from transcript CG5675-RB	0.251
aop	anterior open	0.246
Jra	Jun-related antigen	0.239
HLHmdelta	E(spl) region transcript mdelta	0.236
babo	baboon	0.232
Fmr1	CG6203 gene product from transcript CG6203-RC	0.232
p38b	CG7393 gene product from transcript CG7393-RA	0.220
krz	kurtz	0.218
HLHm7	E(spl) region transcript m7	0.215
Cdc42	CG12530 gene product from transcript CG12530-RA	0.214
NFAT	NFAT homolog	0.210
Socs36E	Suppressor of cytokine signaling at 36E	0.209
zfh1	Zn finger homeodomain 1	0.205
CG13253	CG13253 gene product from transcript CG13253-RB	0.204
Cip4	CG15015 gene product from transcript CG15015-RA	0.200
tws	twins	0.200
sgg	shaggy	0.180
Su(H)	Suppressor of Hairless	0.176
ovo	CG6824 gene product from transcript CG6824-RE	0.169
stck	steamer duck	0.164
EndoGI	Endonuclease G inhibitor	0.160
Ptp69D	Protein tyrosine phosphatase 69D	0.157
p53	CG33336 gene product from transcript CG33336-RB	0.157
Tsp	Thrombospondin	0.156
hipk	homeodomain interacting protein kinase	0.154
Tl	Toll	0.153
pnut	peanut	0.151
Egfr	Epidermal growth factor receptor	0.150
mew	multiple edematous wings	0.149
numb	CG3779 gene product from transcript CG3779-RB	0.148
Pk61C	Protein kinase 61C	0.147
Dhc64C	Dynein heavy chain 64C	0.145
HLHmgamma	E(spl) region transcript mgamma	0.143
sev	sevenless	0.140
Tao-1	CG14217 gene product from transcript CG14217-RF	0.132
CycA	Cyclin A	0.129
Ras64B	Ras oncogene at 64B	0.127
drongo	CG3365 gene product from transcript CG3365-RH	0.125
Mob2	CG11711 gene product from transcript CG11711-RC	0.122
Tsc1	CG6147 gene product from transcript CG6147-RA	0.121
foxo	forkhead box, sub-group O	0.121
pum	pumilio	0.121
Caki	Calcium/calmodulin-dependent protein kinase	0.120
trio	CG18214 gene product from transcript CG18214-RA	0.120
Cdk4	Cyclin-dependent kinase 4	0.119
Stim	Stromal interaction molecule	0.119
dia	diaphanous	0.118
dos	daughter of sevenless	0.117
dnc	dunce	0.116
E(spl)	Enhancer of split	0.115
Hs6st	Heparan sulfate 6-O-sulfotransferase	0.112
dally	division abnormally delayed	0.112
spas	spastin	0.110
Mpk2	CG5475 gene product from transcript CG5475-RB	0.106
gig	gigas	0.105

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Homo sapiens

Name	Description	Probability
EGFR	epidermal growth factor receptor	1.000
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	1.000
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	1.000
RB1	retinoblastoma 1	1.000
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.999
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.999
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.998
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.998
UBC	ubiquitin C	0.998
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.997
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.995
TRAF6	TNF receptor-associated factor 6	0.995
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.995
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.994
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.993
PLCG1	phospholipase C, gamma 1	0.993
MAPK14	mitogen-activated protein kinase 14	0.993
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.993
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.993
MAPK8	mitogen-activated protein kinase 8	0.990
JUN	jun proto-oncogene	0.987
MAPK1	mitogen-activated protein kinase 1	0.986
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.983
DUSP1	dual specificity phosphatase 1	0.981
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.979
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.973
GRB2	growth factor receptor-bound protein 2	0.971
SNX9	sorting nexin 9	0.971
IRAK2	interleukin-1 receptor-associated kinase 2	0.958
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.950
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.949
CCND1	cyclin D1	0.948
FYN	FYN oncogene related to SRC, FGR, YES	0.941
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.939
ARRB1	arrestin, beta 1	0.939
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.938
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.935
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.932
SQSTM1	sequestosome 1	0.931
PRKCZ	protein kinase C, zeta	0.931
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.931
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.930
BBS10	Bardet-Biedl syndrome 10	0.928
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.926
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.923
VAV1	vav 1 guanine nucleotide exchange factor	0.923
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.922
LCK	lymphocyte-specific protein tyrosine kinase	0.920
TP53	tumor protein p53	0.917
IGF1R	insulin-like growth factor 1 receptor	0.917
FGFR2	fibroblast growth factor receptor 2	0.915
LRRK2	leucine-rich repeat kinase 2	0.907
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.906
TOLLIP	toll interacting protein	0.900
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.889
ADAM15	ADAM metallopeptidase domain 15	0.887
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.886
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.885
SMAD3	SMAD family member 3	0.883
SH3KBP1	SH3-domain kinase binding protein 1	0.881
FGFR1	fibroblast growth factor receptor 1	0.876
ESR1	estrogen receptor 1	0.875
SMAD2	SMAD family member 2	0.872
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.864
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.846
CSNK1E	casein kinase 1, epsilon	0.825
CCND3	cyclin D3	0.822
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.816
GAB1	GRB2-associated binding protein 1	0.808
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.807
PTK2	PTK2 protein tyrosine kinase 2	0.806
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.806
CDK6	cyclin-dependent kinase 6	0.804
MAP3K11	mitogen-activated protein kinase kinase kinase 11	0.801
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.791
JUNB	jun B proto-oncogene	0.786
CCNE1	cyclin E1	0.784
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.772
BTRC	beta-transducin repeat containing	0.769
MAP2K4	mitogen-activated protein kinase kinase 4	0.763
CAV1	caveolin 1, caveolae protein, 22kDa	0.758
CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.746
CDK9	cyclin-dependent kinase 9	0.742
C1QA	complement component 1, q subcomponent, A chain	0.729
MAP2K7	mitogen-activated protein kinase kinase 7	0.728
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.727
FLNB	filamin B, beta	0.727
DLG1	discs, large homolog 1 (Drosophila)	0.726
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.723
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.717
MAP2K1	mitogen-activated protein kinase kinase 1	0.717
TSC2	tuberous sclerosis 2	0.713
CREBBP	CREB binding protein	0.711
CDK2	cyclin-dependent kinase 2	0.706
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.705
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.705
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.698
MUC1	mucin 1, cell surface associated	0.687
CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	0.685
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.683

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Mus musculus

Name	Description	Probability
Ctnnb1	catenin (cadherin associated protein), beta 1	1.000
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	1.000
Cbl	Casitas B-lineage lymphoma	0.998
Trp53	transformation related protein 53	0.998
Lepr	leptin receptor	0.998
Pten	phosphatase and tensin homolog	0.997
Apc	adenomatosis polyposis coli	0.997
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.997
Efnb2	ephrin B2	0.993
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.989
Socs1	suppressor of cytokine signaling 1	0.988
Grb2	growth factor receptor bound protein 2	0.988
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.986
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.985
Mapk8	mitogen-activated protein kinase 8	0.982
Gli3	GLI-Kruppel family member GLI3	0.982
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.980
Dab1	disabled homolog 1 (Drosophila)	0.979
Egfr	epidermal growth factor receptor	0.978
Src	Rous sarcoma oncogene	0.978
Rb1	retinoblastoma 1	0.977
Ephb2	Eph receptor B2	0.975
Cd44	CD44 antigen	0.970
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.964
Tnf	tumor necrosis factor	0.961
Rac1	RAS-related C3 botulinum substrate 1	0.961
Ptgs2	prostaglandin-endoperoxide synthase 2	0.959
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.956
Dok1	docking protein 1	0.956
Mdm2	transformed mouse 3T3 cell double minute 2	0.951
Smad3	MAD homolog 3 (Drosophila)	0.950
Vangl2	vang-like 2 (van gogh, Drosophila)	0.939
Fgfr2	fibroblast growth factor receptor 2	0.937
Lyz2	lysozyme 2	0.934
Fos	FBJ osteosarcoma oncogene	0.934
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.932
Yap1	yes-associated protein 1	0.931
Plcg1	phospholipase C, gamma 1	0.929
Axin1	axin 1	0.925
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.920
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.914
Gsk3b	glycogen synthase kinase 3 beta	0.914
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.912
Thbs1	thrombospondin 1	0.900
Flt1	FMS-like tyrosine kinase 1	0.898
Jun	Jun oncogene	0.896
Inpp5d	inositol polyphosphate-5-phosphatase D	0.895
Tgfb2	transforming growth factor, beta 2	0.890
App	amyloid beta (A4) precursor protein	0.889
Il1r1	interleukin 1 receptor, type I	0.885
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.883
Ccnd1	cyclin D1	0.876
Esr1	estrogen receptor 1 (alpha)	0.863
Tsc1	tuberous sclerosis 1	0.858
Nos1	nitric oxide synthase 1, neuronal	0.855
Ret	ret proto-oncogene	0.852
Mapk14	mitogen-activated protein kinase 14	0.833
Tgfbr1	transforming growth factor, beta receptor I	0.833
Trp63	transformation related protein 63	0.833
Axl	AXL receptor tyrosine kinase	0.832
Traf6	TNF receptor-associated factor 6	0.828
Irs1	insulin receptor substrate 1	0.824
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.810
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.807
Csf1	colony stimulating factor 1 (macrophage)	0.805
Fyn	Fyn proto-oncogene	0.805
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.803
Stat3	signal transducer and activator of transcription 3	0.802
Ednrb	endothelin receptor type B	0.791
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.788
Fzd4	frizzled homolog 4 (Drosophila)	0.785
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.780
Insr	insulin receptor	0.770
Arrb2	arrestin, beta 2	0.763
Fbn1	fibrillin 1	0.752
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.751
Braf	Braf transforming gene	0.747
Epas1	endothelial PAS domain protein 1	0.744
Lrp1	low density lipoprotein receptor-related protein 1	0.743
Stk4	serine/threonine kinase 4	0.742
Tgfa	transforming growth factor alpha	0.736
Il6st	interleukin 6 signal transducer	0.731
Efnb1	ephrin B1	0.727
Ptk7	PTK7 protein tyrosine kinase 7	0.722
Klf7	Kruppel-like factor 7 (ubiquitous)	0.716
Nck2	non-catalytic region of tyrosine kinase adaptor protein 2	0.712
Prkce	protein kinase C, epsilon	0.710
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.705
C3ar1	complement component 3a receptor 1	0.705
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.703
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.702
Nf1	neurofibromatosis 1	0.700
Adam12	a disintegrin and metallopeptidase domain 12 (meltrin alpha)	0.699
Gab1	growth factor receptor bound protein 2-associated protein 1	0.698
Ptk2	PTK2 protein tyrosine kinase 2	0.696
Rictor	RPTOR independent companion of MTOR, complex 2	0.694
Trp73	transformation related protein 73	0.687
Ccr1	chemokine (C-C motif) receptor 1	0.686
Il1b	interleukin 1 beta	0.682
Tspan9	tetraspanin 9	0.680

Loading network...

Rattus norvegicus

Name	Description	Probability
Dusp1	dual specificity phosphatase 1	0.598
Sirpa	signal-regulatory protein alpha	0.596
Jak2	Janus kinase 2	0.575
Jun	Jun oncogene	0.509
Inpp5d	inositol polyphosphate-5-phosphatase D	0.366
Grb2	growth factor receptor bound protein 2	0.315
Klf6	Kruppel-like factor 6	0.301
Mr1	major histocompatibility complex, class I-related	0.288
Btg2	BTG family, member 2	0.280
Mapk9	mitogen-activated protein kinase 9	0.261
Junb	jun B proto-oncogene	0.258
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.255
Vav1	vav 1 guanine nucleotide exchange factor	0.239
Nrp1	neuropilin 1	0.222
Atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.220
Agtr1a	angiotensin II receptor, type 1a	0.214
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.210
Prkcd	protein kinase C, delta	0.208
Zfp36	zinc finger protein 36	0.203
Cdh17	cadherin 17	0.201
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.200
Egfr	epidermal growth factor receptor	0.197
Fosl1	fos-like antigen 1	0.196
Errfi1	ERBB receptor feedback inhibitor 1	0.191
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.180
Cd38	CD38 molecule	0.179
Mapk1	mitogen activated protein kinase 1	0.176
Bcan	brevican	0.176
Prdm2	PR domain containing 2, with ZNF domain	0.175
Cmklr1	chemokine-like receptor 1	0.168
Mapk3	mitogen activated protein kinase 3	0.167
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.162
Fos	FBJ osteosarcoma oncogene	0.155
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.152
Vom2r53	vomeronasal 2 receptor, 53	0.152
Grm7	glutamate receptor, metabotropic 7	0.151
Myo1e	myosin IE	0.150
Drd2	dopamine receptor D2	0.149
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.148
Hpca	hippocalcin	0.148
Slc7a12	solute carrier family 7 (cationic amino acid transporter, y+ system), member 12	0.148
Homer3	homer homolog 3 (Drosophila)	0.147
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.146
Tas2r107	taste receptor, type 2, member 107	0.145
Clstn3	calsyntenin 3	0.145
Nsf	N-ethylmaleimide-sensitive factor	0.143
Met	met proto-oncogene	0.137
Mpeg1	macrophage expressed 1	0.137
Gna12	guanine nucleotide binding protein (G protein) alpha 12	0.136
Adrbk1	adrenergic, beta, receptor kinase 1	0.133
Cdc42	cell division cycle 42 (GTP binding protein)	0.132
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.132
Cx3cr1	chemokine (C-X3-C motif) receptor 1	0.132
Pnlip	pancreatic lipase	0.132
Slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	0.131
Trhr	thyrotropin releasing hormone receptor	0.130
Unc5b	unc-5 homolog B (C. elegans)	0.129
Ier2	immediate early response 2	0.128
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.128
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.128
Ptpn7	protein tyrosine phosphatase, non-receptor type 7	0.127
Wdr26	WD repeat domain 26	0.127
RGD1564664	similar to LOC387763 protein	0.124
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.124
Slco2a1	solute carrier organic anion transporter family, member 2a1	0.123
Cfp	complement factor properdin	0.120
Fgfr1	Fibroblast growth factor receptor 1	0.118
Akt1	v-akt murine thymoma viral oncogene homolog 1	0.118
Pctk2	PCTAIRE protein kinase 2	0.118
Stip1	stress-induced phosphoprotein 1	0.117
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.117
Map6	microtubule-associated protein 6	0.117
Smad3	SMAD family member 3	0.116
Myo1b	myosin Ib	0.116
Cd4	Cd4 molecule	0.115
Irs1	insulin receptor substrate 1	0.115
Bdkrb2	bradykinin receptor B2	0.114
Hk1	hexokinase 1	0.112
Egr1	early growth response 1	0.112
Prkch	protein kinase C, eta	0.111
Necab1	N-terminal EF-hand calcium binding protein 1	0.111
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.111
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.110
Prkacb	protein kinase, cAMP dependent, catalytic, beta	0.110
Jak1	Janus kinase 1	0.109
Ptprq	protein tyrosine phosphatase, receptor type, Q	0.109
Utrn	utrophin	0.109
Pcnxl3	pecanex-like 3 (Drosophila)	0.109
Ptafr	platelet-activating factor receptor	0.108
Hpcal4	hippocalcin-like 4	0.107
Tle4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	0.107
Adora2a	adenosine A2a receptor	0.107
Dusp6	dual specificity phosphatase 6	0.106
Scarb1	scavenger receptor class B, member 1	0.105
Ccnd1	cyclin D1	0.105
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.104
Calcrl	calcitonin receptor-like	0.103
Slc9a1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	0.103
Atf3	activating transcription factor 3	0.103
Fgfr2	fibroblast growth factor receptor 2	0.102

Loading network...

Saccharomyces cerevisiae

Name	Description	Probability
PBS2	Pbs2p	0.993
PIL1	Pil1p	0.977
BCK1	Bck1p	0.958
SSK2	Ssk2p	0.956
CLB3	Clb3p	0.926
CKS1	Cks1p	0.924
CLN1	Cln1p	0.921
BOI1	Boi1p	0.900
SHO1	Sho1p	0.887
NBP2	Nbp2p	0.883
ROM2	Rom2p	0.876
CDC28	Cdc28p	0.841
HSL1	Hsl1p	0.826
CDC12	Cdc12p	0.771
CLN2	Cln2p	0.766
SLT2	Slt2p	0.717
SWE1	Swe1p	0.693
DBF2	Dbf2p	0.668
HOG1	Hog1p	0.656
NAP1	Nap1p	0.646
PHO85	Pho85p	0.635
GIN4	Gin4p	0.560
BMH1	Bmh1p	0.544
CLB6	Clb6p	0.543
MSG5	Msg5p	0.529
CLB2	Clb2p	0.522
SIC1	Sic1p	0.513
SSK1	Ssk1p	0.504
STE20	Ste20p	0.481
STE7	Ste7p	0.467
PAM1	Pam1p	0.444
CAK1	Cak1p	0.443
FAR1	Far1p	0.411
SNF1	Snf1p	0.384
SIP1	Sip1p	0.340
GAL83	Gal83p	0.335
TOR1	Tor1p	0.328
BCK2	Bck2p	0.291
PPH21	Pph21p	0.289
FUS3	Fus3p	0.283
MKK1	Mkk1p	0.281
PTC1	Ptc1p	0.276
RAD53	Rad53p	0.273
PHO81	Pho81p	0.256
CLA4	Cla4p	0.256
CDC37	Cdc37p	0.243
SNF4	Snf4p	0.243
RPP1B	Rpp1bp	0.236
EDE1	Ede1p	0.230
PCL9	Pcl9p	0.219
PCL10	Pcl10p	0.217
SIL1	Sil1p	0.217
CDC6	Cdc6p	0.206
SAK1	Sak1p	0.203
PCL1	Pcl1p	0.195
MKK2	Mkk2p	0.189
CDC10	Cdc10p	0.185
SSK22	Ssk22p	0.183
MKS1	Mks1p	0.181
ERO1	Ero1p	0.175
DIA2	Dia2p	0.174
ELP2	Elp2p	0.165
STE4	Ste4p	0.149
BFR1	Bfr1p	0.139
ATG21	Atg21p	0.135
BEM2	Bem2p	0.130
CDC11	Cdc11p	0.129
YPD1	Ypd1p	0.129
SIP2	Sip2p	0.124
CRZ1	Crz1p	0.122
CLB5	Clb5p	0.118
YPL014W	hypothetical protein	0.117
DIG1	Dig1p	0.116
GSY1	Gsy1p	0.114
LHS1	Lhs1p	0.113
ZDS1	Zds1p	0.112
HKR1	Hkr1p	0.111
CDC34	Cdc34p	0.110
CDH1	Cdh1p	0.110
HRR25	Hrr25p	0.109
CLB1	Clb1p	0.101
SLK19	Slk19p	0.100
TOR2	Tor2p	0.097
RPS29B	Rps29bp	0.093
CDC55	Cdc55p	0.092
RLM1	Rlm1p	0.091
KCC4	Kcc4p	0.091
TRA1	Tra1p	0.091
ELP3	Elp3p	0.089
CLB4	Clb4p	0.088
SPC29	Spc29p	0.087
JEM1	Jem1p	0.087
CCW12	Ccw12p	0.086
HIR1	Hir1p	0.083
RRD1	Rrd1p	0.082
AXL2	Axl2p	0.081
PTK2	Ptk2p	0.079
PCL2	Pcl2p	0.079
RPN14	Rpn14p	0.079
RPP0	Rpp0p	0.078