The network for 'regulation of locomotion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of locomotion

Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.

NameDescriptionProbabilityFunc Analog Organism
unc-9Protein UNC-90.994
goa-1Protein GOA-10.992
syg-1Protein SYG-10.947
rig-6Protein RIG-60.931
unc-73Protein UNC-730.930
egl-18Protein EGL-180.900
hlh-2Protein HLH-20.891
nhr-67Protein NHR-670.867
vab-3Protein VAB-30.832
mig-5Protein MIG-50.815
egl-5Protein EGL-50.809
unc-42Protein UNC-420.794
unc-62Protein UNC-620.774
ser-4Protein SER-40.755
lin-11Protein LIN-110.745
egl-8Protein EGL-80.712
spc-1Protein SPC-10.701
lin-45Protein LIN-450.681
ceh-34Protein CEH-340.679
mig-6Protein MIG-60.655
pha-4Protein PHA-40.654
daf-12Protein DAF-120.632
plc-1Protein PLC-10.611
unc-52Protein UNC-520.611
unc-40Protein UNC-400.593
hlh-1Protein HLH-10.582
glr-1Protein GLR-10.573
inx-12Protein INX-120.572
let-60Protein LET-600.560
egl-13Protein EGL-130.558
lin-17Protein LIN-170.548
kgb-1Protein KGB-10.534
trim-9Protein TRIM-90.526
aqp-2Protein AQP-20.506
F52C12.4Protein F52C12.40.502
ifa-1Protein IFA-10.502
eat-4Protein EAT-40.481
apr-1Protein APR-10.478
sdz-28Protein SDZ-280.465
itr-1Protein ITR-10.460
unc-26Protein UNC-260.459
dyb-1Protein DYB-10.448
mes-3Protein MES-30.438
C54E4.2Protein C54E4.20.431
pdfr-1Protein PDFR-10.428
unc-116Protein UNC-1160.426
emb-9Protein EMB-90.426
plc-3Protein PLC-30.418
ceh-20Protein CEH-200.413
math-4Protein MATH-40.410
eor-1Protein EOR-10.407
C13B9.3Protein C13B9.30.404
F28E10.1Protein F28E10.10.399
B0303.2Protein B0303.20.394
imp-2Protein IMP-20.394
ptr-14Protein PTR-140.390
pal-1Protein PAL-10.379
efn-2Protein EFN-20.378
slo-1Protein SLO-10.374
fkh-2Protein FKH-20.373
brp-1Protein BRP-10.373
flt-1Protein FLT-10.372
lat-1Protein LAT-10.372
mpz-2Protein MPZ-20.371
unc-79Protein UNC-790.368
sax-7Protein SAX-70.356
zip-7Protein ZIP-70.355
daf-2Protein DAF-20.350
ccf-1Protein CCF-10.348
rgs-2Protein RGS-20.347
unc-80Protein UNC-800.342
lrp-1Protein LRP-10.340
lag-1Protein LAG-10.332
cnd-1Protein CND-10.332
lin-12Protein LIN-120.331
K03E5.2Protein K03E5.20.326
nlg-1Protein NLG-10.325
clh-5Protein CLH-50.322
eat-2Protein EAT-20.321
unc-7Protein UNC-70.319
sax-3Protein SAX-30.316
sel-7Protein SEL-70.313
pkg-1Protein PKG-10.310
ifb-1Protein IFB-10.310
unc-29Protein UNC-290.305
rpm-1Protein RPM-10.288
egl-30Protein EGL-300.287
ace-1Protein ACE-10.286
ptp-3Protein PTP-30.285
bar-1Protein BAR-10.284
ced-10Protein CED-100.278
acy-1Protein ACY-10.275
hmp-1Protein HMP-10.272
unc-86Protein UNC-860.268
cam-1Protein CAM-10.267
hmr-1Protein HMR-10.262
unc-83Protein UNC-830.261
pars-1Protein PARS-10.254
hsp-3Protein HSP-30.253
pes-7Protein PES-70.253
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
aldh1a2aldehyde dehydrogenase 1 family, member A20.785
shhasonic hedgehog a0.714
bmp2abone morphogenetic protein 2a0.685
ascl1aachaete-scute complex-like 1a (Drosophila)0.583
notch1anotch homolog 1a0.582
sulf1sulfatase 10.563
pitx3paired-like homeodomain transcription factor 30.528
efnb2aephrin B2a0.506
gata2aGATA-binding protein 2a0.503
apoebapolipoprotein Eb0.461
col14a1collagen, type XIV, alpha 10.448
notch3notch homolog 30.410
pkd2polycystic kidney disease 20.407
kdrlkinase insert domain receptor like0.383
wnt8bwingless-type MMTV integration site family, member 8b0.382
spry4sprouty (Drosophila) homolog 40.349
dbx1adeveloping brain homeobox 1a0.339
ptmaaprothymosin, alpha a0.330
tie1endothelium-specific receptor tyrosine kinase 10.320
gli1GLI-Kruppel family member 10.320
tal1T-cell acute lymphocytic leukemia 10.315
tbx1T-box 10.314
cxcr4bchemokine (C-X-C motif), receptor 4b0.311
wnt11rwingless-type MMTV integration site family, member 11, related0.283
sox32SRY-box containing gene 320.283
fli1afriend leukemia integration 1a0.283
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.272
unc5bunc-5 homolog B (C. elegans)0.265
wnt5bwingless-type MMTV integration site family, member 5b0.263
bmp4bone morphogenetic protein 40.263
fras1Fraser syndrome 10.262
ntn1anetrin 1a0.261
dab1bdisabled homolog 1b (Drosophila)0.260
robo3roundabout homolog 30.253
ets1av-ets erythroblastosis virus E26 oncogene homolog 1a0.253
chsy1chondroitin sulfate synthase 10.249
wnt4awingless-type MMTV integration site family, member 4a0.243
myf5myogenic factor 50.239
sim1asingle-minded homolog 1a (Drosophila)0.235
mmp2matrix metalloproteinase 20.232
gli2aGLI-Kruppel family member GLI2a0.230
gli2bGLI-Kruppel family member GLI2b0.225
wnt2bbwingless-type MMTV integration site family, member 2Bb0.222
fn1fibronectin 10.218
esrrgaestrogen-related receptor gamma a0.214
sox17SRY-box containing gene 170.207
foxb1.2forkhead box B1.20.204
plxna4plexin A40.200
ttnatitin a0.192
igf1rainsulin-like growth factor 1a receptor0.192
osr1odd-skipped related 1 (Drosophila)0.190
wnt3wingless-type MMTV integration site family, member 30.189
nrp1aneuropilin 1a0.176
col1a1acollagen, type I, alpha 1a0.176
lhx2bLIM homeobox 2b0.173
postnperiostin, osteoblast specific factor0.170
pkp3plakophilin 30.165
gria4bglutamate receptor, ionotropic, AMPA 4b0.164
odz4odd Oz/ten-m homolog 40.162
tll1tolloid-like 10.162
ephb4aeph receptor B4a0.157
lama2laminin, alpha 20.156
nod1nucleotide-binding oligomerization domain containing 10.156
sh3gl1bSH3-domain GRB2-like 1b0.155
flncbfilamin C, gamma b (actin binding protein 280)0.153
arnt2aryl hydrocarbon receptor nuclear translocator 20.151
mxtx2mix-type homeobox gene 20.150
notum3notum 30.148
neurog1neurogenin 10.146
robo2roundabout homolog 20.146
cdoncell adhesion molecule-related/down-regulated by oncogenes0.145
lrrc33leucine rich repeat containing 330.145
trim33tripartite motif-containing 330.144
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.143
gata6GATA-binding protein 60.143
cdh23cadherin-like 230.140
fgfr4fibroblast growth factor receptor 40.137
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.137
gfra1bgdnf family receptor alpha 1b0.135
yap1Yes-associated protein 10.134
pax8paired box gene 80.133
alcambactivated leukocyte cell adhesion molecule b0.133
lamc1laminin, gamma 10.131
cyt1type I cytokeratin, enveloping layer0.130
smad9MAD homolog 9 (Drosophila)0.127
rx3retinal homeobox gene 30.126
bmp1abone morphogenetic protein 1a0.125
fgf3fibroblast growth factor 30.125
foxa2forkhead box A20.124
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.123
ptch1patched 10.120
plcg1phospholipase C, gamma 10.120
grem2gremlin 2, cysteine knot superfamily0.119
hand2heart and neural crest derivatives expressed transcript 20.118
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
mbcmyoblast city0.957
Rac1CG2248 gene product from transcript CG2248-RA0.758
Itp-r83AInositol 1,4,5,-tris-phosphate receptor0.642
shotshort stop0.538
Pi3K92ECG4141 gene product from transcript CG4141-RB0.533
Fas2Fasciclin 20.509
elavembryonic lethal abnormal vision0.477
trioCG18214 gene product from transcript CG18214-RA0.456
Rho1CG8416 gene product from transcript CG8416-RB0.345
gcmglial cells missing0.316
cpbcapping protein beta0.218
MhcMyosin heavy chain0.204
ovoCG6824 gene product from transcript CG6824-RE0.200
InRInsulin-like receptor0.181
mewmultiple edematous wings0.176
Wnt5Wnt oncogene analog 50.164
awdabnormal wing discs0.156
PvrPDGF- and VEGF-receptor related0.151
phlpole hole0.149
Gyc76CGuanylyl cyclase at 76C0.145
wupAwings up A0.143
rictorrapamycin-insensitive companion of Tor0.132
CaMKIICalcium/calmodulin-dependent protein kinase II0.128
EgfrEpidermal growth factor receptor0.124
Sema-1aCG18405 gene product from transcript CG18405-RD0.121
emsempty spiracles0.121
p130CASCG1212 gene product from transcript CG1212-RA0.121
unc-13CG2999 gene product from transcript CG2999-RA0.115
eyaeyes absent0.103
bowlbrother of odd with entrails limited0.102
EcREcdysone receptor0.101
CdsACDP diglyceride synthetase0.099
Syx1ASyntaxin 1A0.098
MicalMolecule interacting with CasL0.098
myoglianinCG1838 gene product from transcript CG1838-RD0.090
hipkhomeodomain interacting protein kinase0.087
CycACyclin A0.087
Fas3Fasciclin 30.087
GripGlutamate receptor binding protein0.084
RalaRas-related protein0.084
debcldeath executioner Bcl-2 homologue0.082
AblAbl tyrosine kinase0.081
MadMothers against dpp0.081
TrhTryptophan hydroxylase0.079
drkdownstream of receptor kinase0.079
Src42ASrc oncogene at 42A0.078
CG42629CG42629 gene product from transcript CG42629-RB0.077
pgant3polypeptide GalNAc transferase 30.077
CG13253CG13253 gene product from transcript CG13253-RB0.074
neuroliginCG13772 gene product from transcript CG13772-RA0.074
Vap-33-1CG5014 gene product from transcript CG5014-RB0.073
Cdc42CG12530 gene product from transcript CG12530-RA0.071
ThorCG8846 gene product from transcript CG8846-RA0.069
NPFR1neuropeptide F receptor0.068
htshu li tai shao0.064
Pka-C1cAMP-dependent protein kinase 10.064
lqfliquid facets0.064
Rab5Rab-protein 50.062
GgaCG3002 gene product from transcript CG3002-RB0.062
G-salpha60AG protein salpha 60A0.059
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor1.000
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)1.000
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)1.000
PTPN1protein tyrosine phosphatase, non-receptor type 11.000
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)1.000
FYNFYN oncogene related to SRC, FGR, YES1.000
FLNAfilamin A, alpha1.000
FN1fibronectin 10.999
SHC1SHC (Src homology 2 domain containing) transforming protein 10.999
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.999
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.998
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.998
GRB2growth factor receptor-bound protein 20.996
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.995
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.993
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.989
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.986
NCOR2nuclear receptor corepressor 20.985
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.985
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.984
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.976
FGFR2fibroblast growth factor receptor 20.972
IGF1Rinsulin-like growth factor 1 receptor0.972
GSK3Bglycogen synthase kinase 3 beta0.972
PLCG1phospholipase C, gamma 10.972
METmet proto-oncogene (hepatocyte growth factor receptor)0.971
JAG1jagged 10.970
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.966
COL1A1collagen, type I, alpha 10.965
ESR1estrogen receptor 10.964
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.962
ITGB4integrin, beta 40.957
FGFR1fibroblast growth factor receptor 10.955
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.952
COL4A1collagen, type IV, alpha 10.951
APCadenomatous polyposis coli0.950
NTRK3neurotrophic tyrosine kinase, receptor, type 30.949
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.948
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.947
MDM2Mdm2 p53 binding protein homolog (mouse)0.946
AXLAXL receptor tyrosine kinase0.945
YAP1Yes-associated protein 10.944
S100BS100 calcium binding protein B0.938
INSRinsulin receptor0.937
TIMP1TIMP metallopeptidase inhibitor 10.935
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.934
SMAD3SMAD family member 30.933
S100A4S100 calcium binding protein A40.930
CALM1calmodulin 1 (phosphorylase kinase, delta)0.926
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.925
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.922
IL1Binterleukin 1, beta0.916
CAV1caveolin 1, caveolae protein, 22kDa0.915
CCR5chemokine (C-C motif) receptor 50.914
MMP14matrix metallopeptidase 14 (membrane-inserted)0.910
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.910
NTRK2neurotrophic tyrosine kinase, receptor, type 20.908
HDAC1histone deacetylase 10.908
PLAURplasminogen activator, urokinase receptor0.907
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.905
PRKCAprotein kinase C, alpha0.905
VEGFAvascular endothelial growth factor A0.896
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.893
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.888
COL6A1collagen, type VI, alpha 10.882
IGFBP5insulin-like growth factor binding protein 50.882
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.882
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.878
NRP1neuropilin 10.877
PLXND1plexin D10.875
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.875
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.875
ITGB5integrin, beta 50.872
VCAM1vascular cell adhesion molecule 10.868
NOTCH3notch 30.866
TAL1T-cell acute lymphocytic leukemia 10.863
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.861
STRN3striatin, calmodulin binding protein 30.857
IRS1insulin receptor substrate 10.850
CD63CD63 molecule0.850
BMP1bone morphogenetic protein 10.848
KRT8keratin 80.846
SMN1survival of motor neuron 1, telomeric0.846
CCL2chemokine (C-C motif) ligand 20.845
FBLN1fibulin 10.844
MAPTmicrotubule-associated protein tau0.842
LCKlymphocyte-specific protein tyrosine kinase0.839
IGFBP3insulin-like growth factor binding protein 30.833
CDH5cadherin 5, type 2 (vascular endothelium)0.830
THBS1thrombospondin 10.826
GRB10growth factor receptor-bound protein 100.826
S100A14S100 calcium binding protein A140.824
FKBP1AFK506 binding protein 1A, 12kDa0.820
S100A6S100 calcium binding protein A60.817
COL1A2collagen, type I, alpha 20.815
SPTBN1spectrin, beta, non-erythrocytic 10.814
LATlinker for activation of T cells0.813
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.948
Il1binterleukin 1 beta0.821
Pfn1profilin 10.774
Anxa5annexin A50.773
Anxa2annexin A20.731
Hoxa2homeo box A20.713
Nfianuclear factor I/A0.711
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.696
Ptafrplatelet-activating factor receptor0.678
Anxa1annexin A10.662
Ifitm3interferon induced transmembrane protein 30.643
Metmet proto-oncogene0.643
Trib1tribbles homolog 1 (Drosophila)0.624
Calcrlcalcitonin receptor-like0.609
C5ar1complement component 5a receptor 10.592
Flt1FMS-related tyrosine kinase 10.565
Icam1intercellular adhesion molecule 10.552
Myh9myosin, heavy chain 9, non-muscle0.530
Gja5gap junction protein, alpha 50.503
Prkcdprotein kinase C, delta0.503
Adora2aadenosine A2a receptor0.500
Timp2TIMP metallopeptidase inhibitor 20.468
S1pr2sphingosine-1-phosphate receptor 20.463
Il2rginterleukin 2 receptor, gamma0.453
Cxcl13chemokine (C-X-C motif) ligand 130.443
Gnai3guanine nucleotide binding protein (G protein), alpha inhibiting 30.434
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.429
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.414
Gucy1b3guanylate cyclase 1, soluble, beta 30.414
Hckhemopoietic cell kinase0.404
Mmp2matrix metallopeptidase 20.401
Ccl3chemokine (C-C motif) ligand 30.397
Esr2estrogen receptor 2 (ER beta)0.395
Fgf2fibroblast growth factor 20.384
Reg3gregenerating islet-derived 3 gamma0.383
Syt4synaptotagmin IV0.379
Galgalanin prepropeptide0.368
Sstr1somatostatin receptor 10.368
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.367
Mmp10matrix metallopeptidase 100.366
Jak2Janus kinase 20.358
Il8rbinterleukin 8 receptor, beta0.348
Il1r1interleukin 1 receptor, type I0.348
Cgaglycoprotein hormones, alpha polypeptide0.342
Htr1b5-hydroxytryptamine (serotonin) receptor 1B0.340
Fosl1fos-like antigen 10.338
Myadmmyeloid-associated differentiation marker0.328
Sgp158proline-rich glycoprotein (sgp158)0.328
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.323
Cd53Cd53 molecule0.322
Nefmneurofilament, medium polypeptide0.319
Igfbp3insulin-like growth factor binding protein 30.317
Ednrbendothelin receptor type B0.314
Taf10TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor0.313
Vav1vav 1 guanine nucleotide exchange factor0.303
Cnga3cyclic nucleotide gated channel alpha 30.303
Smad3SMAD family member 30.302
Slco2a1solute carrier organic anion transporter family, member 2a10.301
Pstpip1proline-serine-threonine phosphatase-interacting protein 10.301
Sellselectin L0.298
Kcnj8potassium inwardly-rectifying channel, subfamily J, member 80.297
Nmur1neuromedin U receptor 10.296
Anxa4annexin A40.295
Fcgr2aFc fragment of IgG, low affinity IIa, receptor (CD32)0.294
Clic4chloride intracellular channel 40.294
Neflneurofilament, light polypeptide0.291
Il1ainterleukin 1 alpha0.288
Ednraendothelin receptor type A0.287
Myo1bmyosin Ib0.287
Fgfr2fibroblast growth factor receptor 20.286
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.285
Tcf21transcription factor 210.284
Slc22a7solute carrier family 22 (organic anion transporter), member 70.284
Socs3suppressor of cytokine signaling 30.283
Arpc1bactin related protein 2/3 complex, subunit 1B0.282
Tagln2transgelin 20.282
Sox17SRY (sex determining region Y)-box 170.282
Myo1emyosin IE0.281
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.274
Dlgap2discs, large (Drosophila) homolog-associated protein 20.269
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.268
Cpxm2carboxypeptidase X (M14 family), member 20.267
Icosinducible T-cell co-stimulator0.267
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.263
Cxcl2chemokine (C-X-C motif) ligand 20.258
Cd14CD14 molecule0.258
Cxcl10chemokine (C-X-C motif) ligand 100.255
Pax6paired box 60.252
Chrna7cholinergic receptor, nicotinic, alpha 70.249
Grm5glutamate receptor, metabotropic 50.249
Ccl2chemokine (C-C motif) ligand 20.248
Cd44Cd44 molecule0.247
Dnase1l3deoxyribonuclease 1-like 30.246
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism