The network for 'negative regulation of rna biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of rna biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.

NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.989
elt-6Protein ELT-60.937
his-64Protein HIS-640.843
his-61Protein HIS-610.801
his-5Protein HIS-50.750
his-1Protein HIS-10.721
pha-4Protein PHA-40.668
his-48Protein HIS-480.641
hlh-2Protein HLH-20.640
his-31Protein HIS-310.574
his-29Protein HIS-290.498
his-68Protein HIS-680.443
mab-5Protein MAB-50.385
hbl-1Protein HBL-10.376
nhr-67Protein NHR-670.348
egl-46Protein EGL-460.342
mix-1Protein MIX-10.307
nhr-2Protein NHR-20.304
ceh-32Protein CEH-320.278
mat-3Protein MAT-30.269
his-3Protein HIS-30.267
his-16Protein HIS-160.228
lin-53Protein LIN-530.225
cdt-2Protein CDT-20.221
his-9Protein HIS-90.217
daf-14Protein DAF-140.187
hlh-1Protein HLH-10.182
his-51Protein HIS-510.172
plc-1Protein PLC-10.170
rsp-1Protein RSP-10.168
mes-4Protein MES-40.161
prp-8Protein PRP-80.159
let-502Protein LET-5020.156
bar-1Protein BAR-10.155
ten-1Protein TEN-10.155
F39B2.1Protein F39B2.10.145
daf-1Protein DAF-10.145
fkh-2Protein FKH-20.142
tbx-8Protein TBX-80.139
zip-7Protein ZIP-70.137
unc-37Protein UNC-370.136
atg-2Protein ATG-20.135
let-418Protein LET-4180.131
ceh-27Protein CEH-270.131
pop-1Protein POP-10.129
nhr-25Protein NHR-250.127
ran-1Protein RAN-10.125
attf-2Protein ATTF-20.124
daf-21Protein DAF-210.124
his-38Protein HIS-380.119
cnd-1Protein CND-10.117
his-45Protein HIS-450.114
pry-1Protein PRY-10.107
unc-62Protein UNC-620.105
glp-1Protein GLP-10.105
ceh-38Protein CEH-380.105
hcp-3Protein HCP-30.101
csn-4Protein CSN-40.100
mom-2Protein MOM-20.097
fkb-6Protein FKB-60.096
CELE_C23G10.8Protein C23G10.80.096
daf-4Protein DAF-40.095
lsy-2Protein LSY-20.091
bet-2Protein BET-20.091
wrm-1Protein WRM-10.090
mex-5Protein MEX-50.090
rgs-7Protein RGS-70.090
dpy-30Protein DPY-300.090
mep-1Protein MEP-10.089
cam-1Protein CAM-10.089
sel-12Protein SEL-120.088
lsy-22Protein LSY-220.088
lin-17Protein LIN-170.088
npp-12Protein NPP-120.088
sur-2Protein SUR-20.087
his-46Protein HIS-460.086
hda-1Protein HDA-10.086
CELE_F54D5.5Protein F54D5.50.085
fozi-1Protein FOZI-10.085
D1081.8Protein D1081.80.084
T20F7.1Protein T20F7.10.083
mcm-2Protein MCM-20.083
his-6Protein HIS-60.082
npp-21Protein NPP-210.081
lin-13Protein LIN-130.081
flt-1Protein FLT-10.080
daf-3Protein DAF-30.079
egl-13Protein EGL-130.078
T28F4.1Protein T28F4.10.078
prpf-4Protein PRPF-40.077
pdr-1Protein PDR-10.077
eor-1Protein EOR-10.077
egl-38Protein EGL-380.076
dpy-22Protein DPY-220.076
ccch-1Protein CCCH-10.075
his-63Protein HIS-630.075
F33H2.3Protein F33H2.30.075
cul-2Protein CUL-20.075
his-47Protein HIS-470.073
his-72Protein HIS-720.073
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
chdchordin0.859
ndr2nodal-related 20.825
aldh1a2aldehyde dehydrogenase 1 family, member A20.751
gata6GATA-binding protein 60.745
gli1GLI-Kruppel family member 10.599
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.536
dlx3bdistal-less homeobox gene 3b0.500
jag2jagged 20.421
twist3twist30.420
notch1anotch homolog 1a0.412
flhfloating head0.411
per3period homolog 3 (Drosophila)0.393
bmp2bbone morphogenetic protein 2b0.392
dlx2adistal-less homeobox gene 2a0.370
etv2ets variant gene 20.361
sox9bSRY-box containing gene 9b0.344
per2period homolog 2 (Drosophila)0.321
dlcdeltaC0.319
tfap2atranscription factor AP-2 alpha0.315
gata4GATA-binding protein 40.296
spawsouthpaw0.289
sox19bSRY-box containing gene 19b0.276
neurog1neurogenin 10.269
sox32SRY-box containing gene 320.269
her15.1hairy and enhancer of split-related 15.10.263
hmx1H6 homeo box 10.243
sox19aSRY-box containing gene 19a0.230
hnf1baHNF1 homeobox Ba0.229
snai1bsnail homolog 1b (Drosophila)0.228
tcf7transcription factor 7 (T-cell specific, HMG-box)0.223
sesn1sestrin 10.208
mecomMDS1 and EVI1 complex locus0.206
sox2SRY-box containing gene 20.200
tal1T-cell acute lymphocytic leukemia 10.199
fstafollistatin a0.197
vasavasa homolog0.196
lhx1aLIM homeobox 1a0.178
vsx1visual system homeobox 1 homolog, chx10-like0.173
wnt5bwingless-type MMTV integration site family, member 5b0.170
sox10SRY-box containing gene 100.166
zic2azic family member 2 (odd-paired homolog, Drosophila), a0.165
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.165
wt1awilms tumor 1a0.163
dlx6adistal-less homeobox gene 6a0.162
fgf8afibroblast growth factor 8 a0.160
foxa3forkhead box A30.160
pcnaproliferating cell nuclear antigen0.158
hoxa13ahomeo box A13a0.157
foxg1aforkhead box G1a0.156
tbx6T-box gene 60.154
pitx2paired-like homeodomain transcription factor 20.152
meis2.1myeloid ecotropic viral integration site 2.10.150
ptf1apancreas specific transcription factor, 1a0.150
cbx5chromobox homolog 5 (HP1 alpha homolog, Drosophila)0.148
emx1empty spiracles homeobox 10.148
rarabretinoic acid receptor, alpha b0.143
tbx18T-box 180.142
ascl1aachaete-scute complex-like 1a (Drosophila)0.136
tll1tolloid-like 10.135
fgf19fibroblast growth factor 190.135
hoxb1bhomeo box B1b0.134
pax3apaired box gene 3a0.134
her1hairy-related 10.133
rargaretinoic acid receptor gamma a0.133
cry1acryptochrome 1a0.131
lmx1b.1LIM homeobox transcription factor 1, beta 10.128
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.126
her8ahairy-related 8a0.125
robo3roundabout homolog 30.125
gro1groucho 10.125
cdx4caudal type homeo box transcription factor 40.123
foxi3aforkhead box I3a0.123
evx1even-skipped homeobox 10.120
prox1prospero-related homeobox gene 10.120
otpborthopedia homolog b0.119
neo1neogenin 10.119
odz4odd Oz/ten-m homolog 40.117
hoxb3ahomeo box B3a0.117
sall1asal-like 1a (Drosophila)0.114
foxi1forkhead box I10.113
gata5GATA-binding protein 50.113
chrna2acholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)0.110
fgf3fibroblast growth factor 30.110
lhx5LIM homeobox 50.110
ephb3aeph receptor B3a0.110
her11hairy-related 110.110
nkx2.5NK2 transcription factor related 50.109
pou5f1POU domain, class 5, transcription factor 10.105
klf4Kruppel-like factor 40.105
axin2axin 2 (conductin, axil)0.105
ppargperoxisome proliferator activated receptor gamma0.105
tbx16T-box gene 160.104
hmgb1ahigh-mobility group box 1a0.100
hmx3homeo box (H6 family) 30.100
notch1bnotch homolog 1b0.099
runx1runt-related transcription factor 10.098
grem2gremlin 2, cysteine knot superfamily0.094
gdf11growth differentiation factor 110.092
axin1axin 10.091
irx1biroquois homeobox protein 1, b0.091
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Snr1Snf5-related 10.999
brkbrinker0.997
MadMothers against dpp0.996
CTCFCG8591 gene product from transcript CG8591-RA0.996
CtBPC-terminal Binding Protein0.995
hephemipterous0.995
IswiImitation SWI0.994
Sir2CG5216 gene product from transcript CG5216-RA0.994
E(spl)Enhancer of split0.990
atoatonal0.988
ash1absent, small, or homeotic discs 10.988
gppgrappa0.986
shnschnurri0.986
kaykayak0.986
Rpd3CG7471 gene product from transcript CG7471-RA0.985
UbxUltrabithorax0.981
Trf2TATA box binding protein-related factor 20.980
CycBCyclin B0.979
mormoira0.975
D1D1 chromosomal protein0.971
SmrSmrter0.969
E2f2E2F transcription factor 20.968
His2AvHistone H2A variant0.967
Su(var)205Suppressor of variegation 2050.964
dcodiscs overgrown0.962
bowlbrother of odd with entrails limited0.960
salmspalt major0.955
smt3CG4494 gene product from transcript CG4494-RA0.952
osaCG7467 gene product from transcript CG7467-RD0.951
slmbsupernumerary limbs0.950
KrKruppel0.948
Hel25EHelicase at 25E0.943
mus209mutagen-sensitive 2090.940
NNotch0.926
ushu-shaped0.925
mammastermind0.924
panpangolin0.920
araaraucan0.917
ScmSex comb on midleg0.915
toytwin of eyeless0.914
Su(var)3-7Suppressor of variegation 3-70.913
aopanterior open0.908
bratbrain tumor0.907
snssticks and stones0.907
domdomino0.905
Gap1GTPase-activating protein 10.904
hthhomothorax0.903
PclPolycomblike0.900
trxtrithorax0.898
Su(H)Suppressor of Hairless0.896
tlltailless0.895
DrefDNA replication-related element factor0.894
p53CG33336 gene product from transcript CG33336-RB0.888
vasvasa0.888
SerSerrate0.883
HLHm7E(spl) region transcript m70.881
TolloCG6890 gene product from transcript CG6890-RA0.881
eggeggless0.879
gsbgooseberry0.876
emsempty spiracles0.874
par-1CG8201 gene product from transcript CG8201-RA0.870
OptixCG18455 gene product from transcript CG18455-RA0.868
svpseven up0.864
Su(var)2-10Suppressor of variegation 2-100.863
alaristaless0.858
EcREcdysone receptor0.856
B-H2BarH20.847
stysprouty0.841
hkbhuckebein0.840
Su(z)2Suppressor of zeste 20.834
idaimaginal discs arrested0.833
cutletCG33122 gene product from transcript CG33122-RA0.830
Fmr1CG6203 gene product from transcript CG6203-RC0.830
arrarrow0.829
magomago nashi0.829
pdm2POU domain protein 20.829
snostrawberry notch0.825
Abd-BAbdominal B0.824
tuptailup0.820
tintinman0.819
snasnail0.813
pr-set7CG3307 gene product from transcript CG3307-RC0.806
eygeyegone0.805
escextra sexcombs0.805
dppdecapentaplegic0.803
E(var)3-9Enhancer of variegation 3-90.798
BEAF-32Boundary element-associated factor of 32kD0.797
slp1sloppy paired 10.797
Bap170Brahma associated protein 170kD0.789
HLHmdeltaE(spl) region transcript mdelta0.786
phylphyllopod0.785
waplwings apart-like0.779
dacdachshund0.779
Acf1ATP-dependent chromatin assembly factor large subunit0.777
bsblistered0.771
simsingle-minded0.769
Nf-YCNuclear factor Y-box C0.767
twstwins0.751
DpDP transcription factor0.746
LamLamin0.746
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Junbjun B proto-oncogene0.652
Ppp2cbprotein phosphatase 2, catalytic subunit, beta isoform0.609
Zfp36zinc finger protein 360.563
JunJun oncogene0.509
Ifitm3interferon induced transmembrane protein 30.505
Nfibnuclear factor I/B0.434
Id1inhibitor of DNA binding 10.421
Tgfbr2transforming growth factor, beta receptor II0.406
Kdm6blysine (K)-specific demethylase 6B0.401
Vimvimentin0.391
Tcfe2atranscription factor E2a0.357
Errfi1ERBB receptor feedback inhibitor 10.324
Pcnaproliferating cell nuclear antigen0.319
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.311
S100a8S100 calcium binding protein A80.308
Hnrnpkheterogeneous nuclear ribonucleoprotein K0.307
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.301
Rhobras homolog gene family, member B0.295
Btg2BTG family, member 20.295
Eif4heukaryotic translation initiation factor 4H0.292
FosFBJ osteosarcoma oncogene0.284
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.273
Hoxc4homeo box C40.272
Jak1Janus kinase 10.272
Neurog1neurogenin 10.271
Hoxb7homeo box B70.269
Dusp1dual specificity phosphatase 10.264
Socs3suppressor of cytokine signaling 30.256
Hmgb1high mobility group box 10.254
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.250
Dchs1dachsous 1 (Drosophila)0.234
Ptprkprotein tyrosine phosphatase, receptor type, K, extracellular region0.225
Ehmt2euchromatic histone lysine N-methyltransferase 20.222
Hnrnprheterogeneous nuclear ribonucleoprotein R0.220
Klf4Kruppel-like factor 4 (gut)0.217
Hmgn2high mobility group nucleosomal binding domain 20.213
Smad3SMAD family member 30.213
Purbpurine rich element binding protein B0.205
Crybb3crystallin, beta B30.204
Gtf3c2general transcription factor IIIC, polypeptide 2, beta0.200
Trim28tripartite motif-containing 280.197
Dlg1discs, large homolog 1 (Drosophila)0.193
Metmet proto-oncogene0.192
Grin2dglutamate receptor, ionotropic, N-methyl D-aspartate 2D0.191
S100a6S100 calcium binding protein A60.191
Nek9NIMA (never in mitosis gene a)- related kinase 90.187
Ier2immediate early response 20.186
Gastgastrin0.178
Klf6Kruppel-like factor 60.177
Fgfr1Fibroblast growth factor receptor 10.174
Tulp1tubby like protein 10.172
Hand2heart and neural crest derivatives expressed 20.172
Klf2Kruppel-like factor 2 (lung)0.165
Ahraryl hydrocarbon receptor0.165
Ascl1achaete-scute complex homolog 1 (Drosophila)0.165
Shox2short stature homeobox 20.162
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.161
Nrp1neuropilin 10.160
Lpllipoprotein lipase0.160
S100a9S100 calcium binding protein A90.159
Cd9CD9 molecule0.159
Gabrr2gamma-aminobutyric acid (GABA) receptor, rho 20.159
Hnrpdheterogeneous nuclear ribonucleoprotein D0.156
Smc1astructural maintenance of chromosomes 1A0.156
RGD1565591similar to Ski protein0.155
Hes1hairy and enhancer of split 1 (Drosophila)0.154
Smad7SMAD family member 70.153
Hsd3b6hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 60.150
Akap1A kinase (PRKA) anchor protein 10.148
Ssrp1structure specific recognition protein 10.147
Pgam1phosphoglycerate mutase 1 (brain)0.147
Ubtfupstream binding transcription factor, RNA polymerase I0.147
Nfixnuclear factor I/X (CCAAT-binding transcription factor)0.147
Tcf4transcription factor 40.145
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.145
Nr5a2nuclear receptor subfamily 5, group A, member 20.145
Lphn2latrophilin 20.144
Kif1ckinesin family member 1C0.144
Nr5a1nuclear receptor subfamily 5, group A, member 10.143
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.143
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.135
Sox7SRY (sex determining region Y)-box 70.135
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.134
Kcnt1potassium channel, subfamily T, member 10.131
Wbp11WW domain binding protein 110.131
Ccnd1cyclin D10.129
Cd63Cd63 molecule0.129
Ublcp1ubiquitin-like domain containing CTD phosphatase 10.128
Pou3f2POU class 3 homeobox 20.128
Mgpmatrix Gla protein0.127
Ptpn1protein tyrosine phosphatase, non-receptor type 10.126
Cntn4contactin 40.126
Adra2badrenergic, alpha-2B-, receptor0.126
Usf2upstream transcription factor 2, c-fos interacting0.126
Ldhalactate dehydrogenase A0.125
Gspt1G1 to S phase transition 10.125
Arhgap28Rho GTPase activating protein 280.125
Nfyanuclear transcription factor-Y alpha0.124
Cxxc5CXXC finger 50.124
CrebbpCREB binding protein0.124
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
RPD3Rpd3p0.999
HHF1Hhf1p0.997
RAP1Rap1p0.996
RCO1Rco1p0.993
SIR2Sir2p0.989
HDA1Hda1p0.982
SIN3Sin3p0.982
RLF2Rlf2p0.975
RXT2Rxt2p0.969
PHO23Pho23p0.966
HHT1Hht1p0.952
CTI6Cti6p0.951
ISW2Isw2p0.925
SUM1Sum1p0.923
SIR4Sir4p0.922
SET2Set2p0.921
MED2Med2p0.916
SET1Set1p0.907
ASF1Asf1p0.894
SNF1Snf1p0.894
CYC8Cyc8p0.891
SDS3Sds3p0.884
SPT21Spt21p0.879
RTT106Rtt106p0.879
GAL11Gal11p0.872
RPN4Rpn4p0.863
PGD1Pgd1p0.853
SAS2Sas2p0.850
HAT1Hat1p0.838
RIM101Rim101p0.837
GCR2Gcr2p0.827
HOG1Hog1p0.822
FKH2Fkh2p0.817
YTA7Yta7p0.806
ORC2Orc2p0.798
SIN4Sin4p0.793
EAF3Eaf3p0.793
ACT1Act1p0.762
PHO4Pho4p0.761
NUT1Nut1p0.752
CDC14Cdc14p0.750
SPT16Spt16p0.749
FMP48Fmp48p0.742
ADR1Adr1p0.738
ORC5Orc5p0.733
RIF1Rif1p0.727
RLM1Rlm1p0.723
ROX3Rox3p0.711
UBP8Ubp8p0.699
RSC2Rsc2p0.696
RGR1Rgr1p0.692
HHF2Hhf2p0.674
CSE2Cse2p0.665
SSN3Ssn3p0.658
SWI4Swi4p0.656
NAT1Nat1p0.654
MET4Met4p0.652
SDC1Sdc1p0.646
IFH1Ifh1p0.643
ARP4Arp4p0.627
IES3Ies3p0.621
HTZ1Htz1p0.619
HTB2Htb2p0.617
SET3Set3p0.614
HDA3Hda3p0.614
NRG1Nrg1p0.612
SWD1Swd1p0.610
MED1Med1p0.607
RSC4Rsc4p0.605
MTR10Mtr10p0.599
HTB1Htb1p0.596
SIR3Sir3p0.593
SAS4Sas4p0.586
MOT1Mot1p0.585
CTK1Ctk1p0.581
TOM1Tom1p0.573
HMO1Hmo1p0.571
NHP6ANhp6ap0.569
CDC55Cdc55p0.559
SPT10Spt10p0.554
UME1Ume1p0.551
SLX5Slx5p0.540
CDC6Cdc6p0.535
STM1Stm1p0.532
SNT1Snt1p0.521
HIR2Hir2p0.520
GBP2Gbp2p0.508
HSP82Hsp82p0.508
HFI1Hfi1p0.508
CTF18Ctf18p0.508
SCH9Sch9p0.498
RIM20Rim20p0.497
DPB4Dpb4p0.495
RNR2Rnr2p0.493
CHL1Chl1p0.490
NTO1Nto1p0.490
MSN4Msn4p0.486
WHI3Whi3p0.483
TAF5Taf5p0.483
IXR1Ixr1p0.477