The network for 'apoptotic cell clearance' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

apoptotic cell clearance

The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.

NameDescriptionProbabilityFunc Analog Organism
gei-18Protein GEI-180.383
atn-1Protein ATN-10.179
sem-5Protein SEM-50.178
ptr-11Protein PTR-110.161
rab-5Protein RAB-50.135
sas-4Protein SAS-40.134
T19A5.3Protein T19A5.30.119
rme-8Protein RME-80.117
sptl-3Protein SPTL-30.115
rgl-1Protein RGL-10.114
snx-1Protein SNX-10.108
C06E8.5Protein C06E8.50.106
hpo-22Protein HPO-220.101
ptr-6Protein PTR-60.098
lat-1Protein LAT-10.097
R10E11.6Protein R10E11.60.097
unc-73Protein UNC-730.095
ced-3Protein CED-30.092
mex-1Protein MEX-10.092
C52E12.4Protein C52E12.40.092
scpl-2Protein SCPL-20.088
math-3Protein MATH-30.086
hpo-28Protein HPO-280.086
pat-2Protein PAT-20.086
upb-1Protein UPB-10.085
K10C8.3Protein K10C8.30.082
cka-1Protein CKA-10.082
dyn-1Protein DYN-10.081
ubr-1Protein UBR-10.078
slo-1Protein SLO-10.075
skn-1Protein SKN-10.075
taf-1Protein TAF-10.074
F08B12.1Protein F08B12.10.074
swd-2.2Protein SWD-2.20.073
CELE_C16C10.2Protein C16C10.20.072
C29H12.2Protein C29H12.20.072
Y75B7AR.1Protein Y75B7AR.10.071
kin-2Protein KIN-20.070
praf-3Protein PRAF-30.069
C16A3.6Protein C16A3.60.068
vps-37Protein VPS-370.067
npp-7Protein NPP-70.066
arx-2Protein ARX-20.066
acl-14Protein ACL-140.065
F59A3.4Protein F59A3.40.064
CELE_Y39B6A.1Protein Y39B6A.10.064
egl-27Protein EGL-270.064
paqr-3Protein PAQR-30.063
pst-1Protein PST-10.061
F09B12.3Protein F09B12.30.061
zyg-8Protein ZYG-80.060
C14H10.2Protein C14H10.20.059
K02G10.5Protein K02G10.50.059
ZC247.2Protein ZC247.20.059
unc-50Protein UNC-500.059
plc-3Protein PLC-30.058
K04G2.6Protein K04G2.60.058
nra-3Protein NRA-30.058
pld-1Protein PLD-10.058
nhx-9Protein NHX-90.058
pry-1Protein PRY-10.058
F45D3.2Protein F45D3.20.057
ced-6Protein CED-60.057
nhr-3Protein NHR-30.057
Y25C1A.5Protein Y25C1A.50.057
chc-1Protein CHC-10.057
acs-20Protein ACS-200.057
ZC21.3Protein ZC21.30.057
F13D12.3Protein F13D12.30.056
pdhb-1Protein PDHB-10.056
vab-3Protein VAB-30.056
ced-9Protein CED-90.056
snap-29Protein SNAP-290.056
Y106G6A.1Protein Y106G6A.10.056
pat-3Protein PAT-30.055
epg-8Protein EPG-80.055
trim-9Protein TRIM-90.055
unc-43Protein UNC-430.055
cam-1Protein CAM-10.055
mam-3Protein MAM-30.054
T10E9.1Protein T10E9.10.054
avr-14Protein AVR-140.054
tpxl-1Protein TPXL-10.054
ran-5Protein RAN-50.054
ced-10Protein CED-100.054
mig-2Protein MIG-20.054
unc-62Protein UNC-620.054
C33A11.1Protein C33A11.10.053
sar-1Protein SAR-10.053
F13H6.1Protein F13H6.10.053
ptr-14Protein PTR-140.053
atx-2Protein ATX-20.053
C14C11.7Protein C14C11.70.053
riok-3Protein RIOK-30.053
par-1Protein PAR-10.052
M02B7.2Protein M02B7.20.052
zhit-1Protein ZHIT-10.052
C32D5.11Protein C32D5.110.052
egl-30Protein EGL-300.051
F13B12.1Protein F13B12.10.051
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
FhosCG42610 gene product from transcript CG42610-RC0.646
mbcmyoblast city0.622
Rab5Rab-protein 50.618
PvrPDGF- and VEGF-receptor related0.611
Atg1Autophagy-specific gene 10.604
Rho1CG8416 gene product from transcript CG8416-RB0.597
Rac1CG2248 gene product from transcript CG2248-RA0.476
Rac2CG8556 gene product from transcript CG8556-RA0.450
Cdc42CG12530 gene product from transcript CG12530-RA0.336
Rab7Rab-protein 70.238
beta-Specbeta Spectrin0.232
mtsmicrotubule star0.227
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.188
Arc-p34CG10954 gene product from transcript CG10954-RA0.171
reporeversed polarity0.143
DlicDynein light intermediate chain0.143
imdimmune deficiency0.129
ced-6CG11804 gene product from transcript CG11804-RC0.108
plexBplexin B0.108
Rab11Rab-protein 110.090
Eb1CG3265 gene product from transcript CG3265-RF0.088
Pi3K92ECG4141 gene product from transcript CG4141-RB0.082
Arf79FADP ribosylation factor 79F0.082
CG10743CG10743 gene product from transcript CG10743-RB0.081
Vps16AVacuolar protein sorting 16A0.062
PknProtein kinase related to protein kinase N0.062
mewmultiple edematous wings0.060
RalaRas-related protein0.059
fkhfork head0.055
Src42ASrc oncogene at 42A0.053
Tak1TGF-beta activated kinase 10.053
Orc5Origin recognition complex subunit 50.052
Gef26CG9491 gene product from transcript CG9491-RB0.052
Akt1CG4006 gene product from transcript CG4006-RA0.049
stumpsCG31317 gene product from transcript CG31317-RC0.047
GripGlutamate receptor binding protein0.045
inaDinactivation no afterpotential D0.043
nimC4nimrod C40.040
Sop2Suppressor of profilin 20.036
Letm1CG4589 gene product from transcript CG4589-RB0.036
zfh1Zn finger homeodomain 10.034
Galpha49BG protein alpha49B0.032
CG16718CG16718 gene product from transcript CG16718-RA0.030
PcafCG4107 gene product from transcript CG4107-RA0.029
DokDownstream of kinase0.028
Pink1PTEN-induced putative kinase 10.028
Mef2Myocyte enhancer factor 20.027
StimStromal interaction molecule0.026
CG3563CG3563 gene product from transcript CG3563-RA0.025
crncrooked neck0.024
DAAMDishevelled Associated Activator of Morphogenesis0.024
Mkp3Mitogen-activated protein kinase phosphatase 30.024
r2d2CG7138 gene product from transcript CG7138-RB0.024
Pi3K68DPhosphotidylinositol 3 kinase 68D0.023
CG1129CG1129 gene product from transcript CG1129-RC0.023
CG9801CG9801 gene product from transcript CG9801-RC0.023
Mmp1Matrix metalloproteinase 10.022
myoglianinCG1838 gene product from transcript CG1838-RD0.022
vavCG7893 gene product from transcript CG7893-RB0.022
l(1)G0020lethal (1) G00200.022
MED4Mediator complex subunit 40.021
Hs6stHeparan sulfate 6-O-sulfotransferase0.021
Ost48Oligosaccharyltransferase 48kD subunit0.021
Vrp1Verprolin 10.021
Pak3CG14895 gene product from transcript CG14895-RA0.021
MED15Mediator complex subunit 150.020
CG4680CG4680 gene product from transcript CG4680-RA0.020
CG4306CG4306 gene product from transcript CG4306-RA0.019
JraJun-related antigen0.019
PpcsPhosphopantothenoylcysteine synthetase0.019
Wnt5Wnt oncogene analog 50.019
chbchromosome bows0.019
wbwing blister0.019
Dcp-1Death caspase-10.018
CG1468CG1468 gene product from transcript CG1468-RA0.018
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.992
FN1fibronectin 10.978
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.722
CASP8caspase 8, apoptosis-related cysteine peptidase0.657
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.626
SH3KBP1SH3-domain kinase binding protein 10.538
ACTR3ARP3 actin-related protein 3 homolog (yeast)0.491
EGFRepidermal growth factor receptor0.405
RXRAretinoid X receptor, alpha0.313
ANXA1annexin A10.312
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.305
SNX6sorting nexin 60.281
FGF1fibroblast growth factor 1 (acidic)0.277
CFLARCASP8 and FADD-like apoptosis regulator0.234
CASP10caspase 10, apoptosis-related cysteine peptidase0.217
FASLGFas ligand (TNF superfamily, member 6)0.187
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.186
GRB2growth factor receptor-bound protein 20.156
AXLAXL receptor tyrosine kinase0.150
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.149
MAP2K4mitogen-activated protein kinase kinase 40.142
ATF2activating transcription factor 20.138
ARPC2actin related protein 2/3 complex, subunit 2, 34kDa0.122
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.121
TNFRSF10Atumor necrosis factor receptor superfamily, member 10a0.117
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 10.109
RAPGEF1Rap guanine nucleotide exchange factor (GEF) 10.097
ARPC5actin related protein 2/3 complex, subunit 5, 16kDa0.095
MAPK8mitogen-activated protein kinase 80.091
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.090
ARFGEF2ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)0.083
PRKAR1Aprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)0.082
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.081
ATG13ATG13 autophagy related 13 homolog (S. cerevisiae)0.079
LATlinker for activation of T cells0.072
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.071
GAS6growth arrest-specific 60.069
JUNjun proto-oncogene0.068
SMPD1sphingomyelin phosphodiesterase 1, acid lysosomal0.066
ABI1abl-interactor 10.056
MAP3K1mitogen-activated protein kinase kinase kinase 10.055
RAB1ARAB1A, member RAS oncogene family0.052
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.050
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.048
FGFR1fibroblast growth factor receptor 10.044
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.044
POLA2polymerase (DNA directed), alpha 2 (70kD subunit)0.042
ADAM19ADAM metallopeptidase domain 190.040
PDCD6IPprogrammed cell death 6 interacting protein0.039
ACTR2ARP2 actin-related protein 2 homolog (yeast)0.038
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.037
FGFR2fibroblast growth factor receptor 20.036
CAP1CAP, adenylate cyclase-associated protein 1 (yeast)0.036
RHOAras homolog gene family, member A0.036
SLMAPsarcolemma associated protein0.034
RARAretinoic acid receptor, alpha0.033
RAB7ARAB7A, member RAS oncogene family0.033
MED25mediator complex subunit 250.032
DYNLT3dynein, light chain, Tctex-type 30.031
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.031
ITGB5integrin, beta 50.030
APOEapolipoprotein E0.030
ANXA2annexin A20.030
POLA1polymerase (DNA directed), alpha 1, catalytic subunit0.030
FNBP1formin binding protein 10.029
SESN2sestrin 20.029
PICALMphosphatidylinositol binding clathrin assembly protein0.029
ARPC3actin related protein 2/3 complex, subunit 3, 21kDa0.028
U2AF1U2 small nuclear RNA auxiliary factor 10.027
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.027
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.027
NXF1nuclear RNA export factor 10.026
IQGAP1IQ motif containing GTPase activating protein 10.026
SOS1son of sevenless homolog 1 (Drosophila)0.025
KIF5Bkinesin family member 5B0.024
CTGFconnective tissue growth factor0.024
NCKAP1NCK-associated protein 10.023
RB1CC1RB1-inducible coiled-coil 10.023
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.023
FASFas (TNF receptor superfamily, member 6)0.022
APPamyloid beta (A4) precursor protein0.022
EPS8epidermal growth factor receptor pathway substrate 80.022
NAV1neuron navigator 10.021
WASLWiskott-Aldrich syndrome-like0.021
FADDFas (TNFRSF6)-associated via death domain0.021
BCORBCL6 corepressor0.021
MAPK6mitogen-activated protein kinase 60.020
FYNFYN oncogene related to SRC, FGR, YES0.020
ADAM15ADAM metallopeptidase domain 150.020
SETDB1SET domain, bifurcated 10.018
PDHXpyruvate dehydrogenase complex, component X0.018
SH3GL2SH3-domain GRB2-like 20.018
NCOA1nuclear receptor coactivator 10.018
CD247CD247 molecule0.018
ARRB1arrestin, beta 10.017
NDEL1nudE nuclear distribution gene E homolog (A. nidulans)-like 10.017
ADAM9ADAM metallopeptidase domain 90.017
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.785
Ctnnb1catenin (cadherin associated protein), beta 10.649
AxlAXL receptor tyrosine kinase0.636
Lyz2lysozyme 20.522
Apoeapolipoprotein E0.501
Map3k14mitogen-activated protein kinase kinase kinase 140.398
Ptenphosphatase and tensin homolog0.334
Gsk3bglycogen synthase kinase 3 beta0.318
Itgb1integrin beta 1 (fibronectin receptor beta)0.287
Lrp1low density lipoprotein receptor-related protein 10.286
Mapk8ip3mitogen-activated protein kinase 8 interacting protein 30.212
Tlr4toll-like receptor 40.167
Cxcr4chemokine (C-X-C motif) receptor 40.143
Itgb2integrin beta 20.141
Nr3c1nuclear receptor subfamily 3, group C, member 10.140
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.107
Cd44CD44 antigen0.103
Tyro3TYRO3 protein tyrosine kinase 30.100
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.098
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.098
Ndel1nuclear distribution gene E-like homolog 1 (A. nidulans)0.091
Axin1axin 10.088
Npc1Niemann Pick type C10.088
Il6stinterleukin 6 signal transducer0.079
Ptk2PTK2 protein tyrosine kinase 20.077
Rbl2retinoblastoma-like 20.072
Gab1growth factor receptor bound protein 2-associated protein 10.067
Rxraretinoid X receptor alpha0.066
Cav1caveolin 1, caveolae protein0.065
Mapk14mitogen-activated protein kinase 140.063
Itsn1intersectin 1 (SH3 domain protein 1A)0.062
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.057
Tbx3T-box 30.049
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.047
Mmp9matrix metallopeptidase 90.044
Osmroncostatin M receptor0.044
Adamts1a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10.044
Lgals1lectin, galactose binding, soluble 10.043
Bmpr1abone morphogenetic protein receptor, type 1A0.042
Lgals3lectin, galactose binding, soluble 30.042
Selpselectin, platelet0.041
Itgb3integrin beta 30.040
Mapk9mitogen-activated protein kinase 90.040
Twsg1twisted gastrulation homolog 1 (Drosophila)0.040
Lrp6low density lipoprotein receptor-related protein 60.039
Il1binterleukin 1 beta0.038
Mapk8ip2mitogen-activated protein kinase 8 interacting protein 20.038
Il1r1interleukin 1 receptor, type I0.036
Apcadenomatosis polyposis coli0.035
Nf2neurofibromatosis 20.035
Abl1c-abl oncogene 1, non-receptor tyrosine kinase0.035
Tmem38btransmembrane protein 38B0.035
Il10rainterleukin 10 receptor, alpha0.032
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.032
Fgfr1fibroblast growth factor receptor 10.032
Smad3MAD homolog 3 (Drosophila)0.032
Ltblymphotoxin B0.031
Casp4caspase 4, apoptosis-related cysteine peptidase0.031
Ccr1chemokine (C-C motif) receptor 10.030
Ccr2chemokine (C-C motif) receptor 20.029
S100a6S100 calcium binding protein A6 (calcyclin)0.029
Dckdeoxycytidine kinase0.029
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.029
Cd9CD9 antigen0.029
Cxcl13chemokine (C-X-C motif) ligand 130.028
C3complement component 30.028
Trp63transformation related protein 630.028
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.027
Pacsin1protein kinase C and casein kinase substrate in neurons 10.027
Plxnd1plexin D10.027
Vangl2vang-like 2 (van gogh, Drosophila)0.026
Inpp5dinositol polyphosphate-5-phosphatase D0.025
Phexphosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)0.024
Mdm2transformed mouse 3T3 cell double minute 20.024
Igf1insulin-like growth factor 10.024
Mertkc-mer proto-oncogene tyrosine kinase0.024
Mcm4minichromosome maintenance deficient 4 homolog (S. cerevisiae)0.024
Cd28CD28 antigen0.024
Rdh8retinol dehydrogenase 80.024
Atg13ATG13 autophagy related 13 homolog (S. cerevisiae)0.023
Csf1colony stimulating factor 1 (macrophage)0.023
Dlg4discs, large homolog 4 (Drosophila)0.023
Klf5Kruppel-like factor 50.023
Sema3fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F0.023
Tlr2toll-like receptor 20.022
Pthlhparathyroid hormone-like peptide0.022
Ldlrlow density lipoprotein receptor0.022
Arhgap1Rho GTPase activating protein 10.022
LitafLPS-induced TN factor0.022
Stim2stromal interaction molecule 20.021
Pou2af1POU domain, class 2, associating factor 10.021
S100a11S100 calcium binding protein A11 (calgizzarin)0.021
Ednraendothelin receptor type A0.021
Mvpmajor vault protein0.021
Irf5interferon regulatory factor 50.021
Nde1nuclear distribution gene E homolog 1 (A nidulans)0.021
Icam1intercellular adhesion molecule 10.020
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism