The network for 'programmed cell death' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

programmed cell death

A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.

NameDescriptionProbabilityFunc Analog Organism
lmn-1Protein LMN-10.892
par-5Protein PAR-50.827
vab-3Protein VAB-30.793
hsp-1Protein HSP-10.792
sem-5Protein SEM-50.785
rpl-18Protein RPL-180.736
nud-2Protein NUD-20.690
oma-1Protein OMA-10.672
inx-3Protein INX-30.665
lin-36Protein LIN-360.664
rpl-16Protein RPL-160.655
vha-8Protein VHA-80.624
rpa-1Protein RPA-10.619
ifg-1Protein IFG-10.616
pmk-1Protein PMK-10.583
lin-35Protein LIN-350.580
glp-1Protein GLP-10.569
hum-5Protein HUM-50.559
nhr-67Protein NHR-670.555
egg-6Protein EGG-60.554
skr-8Protein SKR-80.550
acs-4Protein ACS-40.545
pdr-1Protein PDR-10.545
unc-40Protein UNC-400.539
rps-2Protein RPS-20.537
his-47Protein HIS-470.536
gex-3Protein GEX-30.533
R10E4.1Protein R10E4.10.533
rpl-5Protein RPL-50.527
CELE_F14E5.2Protein F14E5.20.519
CELE_C49F5.6Protein C49F5.60.508
snr-4Protein SNR-40.508
pas-6Protein PAS-60.506
rps-5Protein RPS-50.504
Y65B4BR.5Protein Y65B4BR.50.504
C10G11.7Protein C10G11.70.502
rad-51Protein RAD-510.500
C37A2.8Protein C37A2.80.498
taf-9Protein TAF-90.498
CELE_C12D8.1Protein C12D8.10.497
eef-1GProtein EEF-1G0.495
skr-14Protein SKR-140.495
F39B2.1Protein F39B2.10.485
let-70Protein LET-700.481
gck-2Protein GCK-20.475
mua-6Protein MUA-60.472
ran-1Protein RAN-10.469
C53B4.4Protein C53B4.40.467
lat-1Protein LAT-10.467
ndk-1Protein NDK-10.462
oma-2Protein OMA-20.461
cra-1Protein CRA-10.460
rme-2Protein RME-20.452
rars-1Protein RARS-10.452
F14B4.2Protein F14B4.20.450
eftu-2Protein EFTU-20.450
kle-2Protein KLE-20.449
sax-7Protein SAX-70.449
rpl-19Protein RPL-190.447
egl-46Protein EGL-460.443
H21P03.2Protein H21P03.20.442
pha-4Protein PHA-40.441
mut-7Protein MUT-70.440
rpl-3Protein RPL-30.440
egl-44Protein EGL-440.439
mom-2Protein MOM-20.435
act-4Protein ACT-40.435
rpl-24.1Protein RPL-24.10.433
T27A3.1Protein T27A3.10.432
act-3Protein ACT-30.429
npp-15Protein NPP-150.427
tol-1Protein TOL-10.427
vab-1Protein VAB-10.427
rps-4Protein RPS-40.424
set-1Protein SET-10.424
rps-21Protein RPS-210.420
pas-1Protein PAS-10.419
mut-14Protein MUT-140.418
rpl-35Protein RPL-350.416
par-3Protein PAR-30.416
alx-1Protein ALX-10.410
hum-6Protein HUM-60.409
mig-5Protein MIG-50.407
bath-42Protein BATH-420.407
dlk-1Protein DLK-10.407
pdfr-1Protein PDFR-10.406
crt-1Protein CRT-10.405
T11G6.8Protein T11G6.80.403
rps-12Protein RPS-120.403
cas-2Protein CAS-20.398
F49C12.9Protein F49C12.90.397
app-1Protein APP-10.393
fkh-2Protein FKH-20.392
lin-23Protein LIN-230.392
pbs-3Protein PBS-30.390
nra-1Protein NRA-10.390
inx-13Protein INX-130.389
mat-3Protein MAT-30.387
npp-22Protein NPP-220.387
vps-26Protein VPS-260.385
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tp53tumor protein p530.949
sema3aasemaphorin 3aa0.914
efnb2aephrin B2a0.848
tbx1T-box 10.789
fgfr1afibroblast growth factor receptor 1a0.783
hspa5heat shock protein 50.727
gli1GLI-Kruppel family member 10.690
myod1myogenic differentiation 10.634
gnb2l1guanine nucleotide binding protein (G protein), beta polypeptide 2-like 10.629
nkx2.3NK2 transcription factor related 30.583
csnk1dacasein kinase 1, delta a0.573
atoh1aatonal homolog 1a0.561
zgc:92237zgc:922370.535
evx1even-skipped homeobox 10.530
mpxmyeloid-specific peroxidase0.528
trpm7transient receptor potential cation channel, subfamily M, member 70.513
fn1fibronectin 10.509
ndr2nodal-related 20.505
thtyrosine hydroxylase0.496
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.492
alcambactivated leukocyte cell adhesion molecule b0.489
kitakit receptor a0.487
cct6achaperonin containing TCP1, subunit 6A (zeta 1)0.481
oprk1opioid receptor, kappa 10.478
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.476
ptch2patched 20.475
pax7apaired box gene 7a0.472
wnt7aawingless-type MMTV integration site family, member 7Aa0.467
rpl13ribosomal protein L130.466
bocbrother of CDO0.462
bbc3BCL2 binding component 30.457
kdrlkinase insert domain receptor like0.451
baxabcl2-associated X protein, a0.451
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.441
lmx1b.1LIM homeobox transcription factor 1, beta 10.436
rpl19ribosomal protein L190.429
hgfbhepatocyte growth factor b0.429
mgaMAX gene associated0.423
pitx3paired-like homeodomain transcription factor 30.418
tbx20T-box 200.411
tp63tumor protein p630.410
dccdeleted in colorectal carcinoma0.405
rplp0ribosomal protein, large, P00.402
atp6v1baATPase, H+ transporting, lysosomal, V1 subunit B, member a0.396
gata3GATA-binding protein 30.395
spry4sprouty (Drosophila) homolog 40.393
id3inhibitor of DNA binding 30.385
sf3b1splicing factor 3b, subunit 10.382
lmnalamin A0.382
lef1lymphocyte enhancer binding factor 10.380
pea3ETS-domain transcription factor pea30.379
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.378
shhasonic hedgehog a0.375
cmybtranscription factor cmyb0.369
lhx1aLIM homeobox 1a0.363
wnt2bbwingless-type MMTV integration site family, member 2Bb0.363
foxo3bforkhead box O3b0.361
hsd3b7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase0.356
plxnb2aplexin b2a0.350
rpl7aribosomal protein L7a0.348
h2afvH2A histone family, member V0.348
rpl23aribosomal protein L23a0.333
chdchordin0.332
lamc1laminin, gamma 10.330
bmp2bbone morphogenetic protein 2b0.328
tnctenascin C0.321
rpsaribosomal protein SA0.320
cpsf1cleavage and polyadenylation specific factor 10.317
rorcaRAR-related orphan receptor C a0.315
hmgb2bhigh-mobility group box 2b0.312
zgc:85866zgc:858660.311
rargaretinoic acid receptor gamma a0.311
otpaorthopedia homolog a0.311
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.308
mcl1amyeloid cell leukemia sequence 1a0.306
gpr126G protein-coupled receptor 1260.304
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.304
flncbfilamin C, gamma b (actin binding protein 280)0.302
tnfrsfatumor necrosis factor receptor superfamily, member a0.297
dusp6dual specificity phosphatase 60.295
bnip3lbBCL2/adenovirus E1B interacting protein 3-like b0.292
fstafollistatin a0.292
gata6GATA-binding protein 60.291
eif3haeukaryotic translation initiation factor 3, subunit H, a0.286
bnc2basonuclin 20.281
ahr2aryl hydrocarbon receptor 20.281
yap1Yes-associated protein 10.278
esr2aestrogen receptor 2a0.277
plcg1phospholipase C, gamma 10.277
nrg2aneuregulin 2a0.277
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.274
piwil1piwi-like 1 (Drosophila)0.274
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.274
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.273
rpl18aribosomal protein L18a0.272
gadd45aagrowth arrest and DNA-damage-inducible, alpha, a0.270
wnt8bwingless-type MMTV integration site family, member 8b0.267
sox2SRY-box containing gene 20.265
hspa4aheat shock protein 4a0.262
nfkbiaanuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a0.262
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
nejnejire0.999
CG11347CG11347 gene product from transcript CG11347-RE0.989
cicubitus interruptus0.978
Pi3K92ECG4141 gene product from transcript CG4141-RB0.975
Atg1Autophagy-specific gene 10.971
MoeMoesin0.967
DrefDNA replication-related element factor0.945
p53CG33336 gene product from transcript CG33336-RB0.945
slmbsupernumerary limbs0.925
rapretina aberrant in pattern0.922
kiskismet0.920
Aos1CG12276 gene product from transcript CG12276-RA0.902
saxsaxophone0.877
HHairless0.866
alpha-Catalpha Catenin0.860
crolcrooked legs0.856
jingCG9397 gene product from transcript CG9397-RI0.849
sdscalloped0.847
Tak1TGF-beta activated kinase 10.845
hephemipterous0.829
Dcp-1Death caspase-10.821
Nop60BNucleolar protein at 60B0.819
putpunt0.810
Akt1CG4006 gene product from transcript CG4006-RA0.808
BEAF-32Boundary element-associated factor of 32kD0.802
vvlventral veins lacking0.794
RbfRetinoblastoma-family protein0.792
SodSuperoxide dismutase0.792
rprreaper0.788
CG7998CG7998 gene product from transcript CG7998-RA0.778
Stat92ESignal-transducer and activator of transcription protein at 92E0.770
Pi3K59FPhosphotidylinositol 3 kinase 59F0.770
Eip93FCG18389 gene product from transcript CG18389-RB0.752
tshteashirt0.742
jarjaguar0.730
shishibire0.729
dmdiminutive0.727
PtenCG5671 gene product from transcript CG5671-RB0.723
Src42ASrc oncogene at 42A0.718
CblCG7037 gene product from transcript CG7037-RB0.708
RASSF8CG5053 gene product from transcript CG5053-RA0.699
Trf2TATA box binding protein-related factor 20.698
eIF-4aEukaryotic initiation factor 4a0.697
Atg9Autophagy-specific gene 90.696
fkhfork head0.693
smosmoothened0.690
gcmglial cells missing0.682
apapterous0.682
twstwins0.682
CG10267CG10267 gene product from transcript CG10267-RB0.679
snostrawberry notch0.678
hydhyperplastic discs0.653
mus209mutagen-sensitive 2090.650
AtpalphaNa pump alpha subunit0.648
drkdownstream of receptor kinase0.640
Pink1PTEN-induced putative kinase 10.635
Atg8aAutophagy-specific gene 8a0.635
Sra-1specifically Rac1-associated protein 10.628
dupdouble parked0.626
SoxNSoxNeuro0.616
msnmisshapen0.614
phlpole hole0.612
p38bCG7393 gene product from transcript CG7393-RA0.606
wtswarts0.605
shnschnurri0.602
kugkugelei0.602
Sgtsmall glutamine-rich tetratricopeptide containing protein0.599
PsnPresenilin0.597
kaykayak0.595
Sec61alphaCG9539 gene product from transcript CG9539-RA0.594
Arp14DActin-related protein 14D0.587
EgfrEpidermal growth factor receptor0.587
AGO1Argonaute-10.585
S6kRPS6-p70-protein kinase0.585
Su(H)Suppressor of Hairless0.583
MAGECG10059 gene product from transcript CG10059-RA0.576
UtxCG5640 gene product from transcript CG5640-RD0.573
CycGCyclin G0.570
klarklarsicht0.568
tsrtwinstar0.568
Eip74EFEcdysone-induced protein 74EF0.568
skpACG16983 gene product from transcript CG16983-RD0.567
RpL14Ribosomal protein L140.567
Trip1CG8882 gene product from transcript CG8882-RA0.567
shgshotgun0.557
hthhomothorax0.556
rinrasputin0.554
G-salpha60AG protein salpha 60A0.548
CG14869CG14869 gene product from transcript CG14869-RB0.547
uspultraspiracle0.545
Art4Arginine methyltransferase 40.545
trptransient receptor potential0.543
rlrolled0.540
dacdachshund0.536
cathDCG1548 gene product from transcript CG1548-RA0.533
Pp2B-14DProtein phosphatase 2B at 14D0.531
stysprouty0.529
Vap-33-1CG5014 gene product from transcript CG5014-RB0.527
l(2)gllethal (2) giant larvae0.523
Hel25EHelicase at 25E0.516
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Anxa4annexin A40.824
Anxa2annexin A20.823
Fgfr2fibroblast growth factor receptor 20.812
Errfi1ERBB receptor feedback inhibitor 10.799
Mapk3mitogen activated protein kinase 30.790
Adora2aadenosine A2a receptor0.788
Fgd4FYVE, RhoGEF and PH domain containing 40.728
Prkcgprotein kinase C, gamma0.719
Agtr1aangiotensin II receptor, type 1a0.701
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.696
Cd44Cd44 molecule0.670
Hspb1heat shock protein 10.660
Cd9CD9 molecule0.653
C1qbcomplement component 1, q subcomponent, B chain0.639
Cd14CD14 molecule0.635
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.628
Anxa5annexin A50.614
Tgfbr2transforming growth factor, beta receptor II0.605
Klf4Kruppel-like factor 4 (gut)0.604
S100a10S100 calcium binding protein A100.599
Ctdsp1CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 10.592
Ptprcprotein tyrosine phosphatase, receptor type, C0.590
Hsph1heat shock 105/110 protein 10.588
Alox5aparachidonate 5-lipoxygenase activating protein0.582
Id3inhibitor of DNA binding 30.581
Junbjun B proto-oncogene0.575
Vat1vesicle amine transport protein 1 homolog (T californica)0.553
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.552
Cdc42cell division cycle 42 (GTP binding protein)0.549
Arpc1bactin related protein 2/3 complex, subunit 1B0.549
Tpm3tropomyosin 3, gamma0.548
S100a9S100 calcium binding protein A90.538
Cd4Cd4 molecule0.537
Nr4a3nuclear receptor subfamily 4, group A, member 30.533
Lgals3lectin, galactoside-binding, soluble, 30.532
Egr1early growth response 10.527
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.517
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.515
Gjb3gap junction protein, beta 30.505
Ptafrplatelet-activating factor receptor0.504
Gadd45agrowth arrest and DNA-damage-inducible, alpha0.500
FosFBJ osteosarcoma oncogene0.500
Ahsgalpha-2-HS-glycoprotein0.488
Egr2early growth response 20.484
Txnrd1thioredoxin reductase 10.479
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.474
Tnfsf4tumor necrosis factor (ligand) superfamily, member 40.468
Jak2Janus kinase 20.463
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.461
Pdia6protein disulfide isomerase family A, member 60.458
Mgpmatrix Gla protein0.457
RorbRAR-related orphan receptor B0.452
Dusp1dual specificity phosphatase 10.452
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.448
Mapk1mitogen activated protein kinase 10.445
Tpothyroid peroxidase0.443
Zyxzyxin0.442
Stip1stress-induced phosphoprotein 10.437
Slco2b1solute carrier organic anion transporter family, member 2b10.433
Ccr2chemokine (C-C motif) receptor 20.432
Ctrlchymotrypsin-like0.432
Ctsscathepsin S0.432
Pkm2pyruvate kinase, muscle0.430
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.429
Itgamintegrin, alpha M0.426
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.422
LOC100362824caveolin 2-like0.421
Pf4platelet factor 40.420
Reg3aregenerating islet-derived 3 alpha0.419
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.416
Impdh2IMP (inosine monophosphate) dehydrogenase 20.412
Rap1bRAP1B, member of RAS oncogene family0.412
Dnajb1DnaJ (Hsp40) homolog, subfamily B, member 10.411
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.410
Icam1intercellular adhesion molecule 10.409
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.407
Itgb1integrin, beta 10.407
Dctn4dynactin 40.405
FaslgFas ligand (TNF superfamily, member 6)0.404
Gabrpgamma-aminobutyric acid (GABA-A) receptor, pi0.404
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.401
Mdm2Mdm2 p53 binding protein homolog (mouse)0.398
Socs3suppressor of cytokine signaling 30.392
Cyp21a1cytochrome P450, family 21, subfamily a, polypeptide 10.391
Hoxa2homeo box A20.388
Litaflipopolysaccharide-induced TNF factor0.387
Robo1roundabout homolog 1 (Drosophila)0.387
Cd74Cd74 molecule, major histocompatibility complex, class II invariant chain0.385
Ccnd3cyclin D30.380
Epoerythropoietin0.379
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.378
Prkar2aprotein kinase, cAMP dependent regulatory, type II alpha0.376
Btg2BTG family, member 20.376
Arandrogen receptor0.376
C5ar1complement component 5a receptor 10.375
Dnase1l3deoxyribonuclease 1-like 30.375
LOC312273Trypsin V-A0.375
Lims1LIM and senescent cell antigen-like domains 10.374
Fosl1fos-like antigen 10.373
JunJun oncogene0.373
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
HSP82Hsp82p0.329
RPS1ARps1ap0.173
SLA1Sla1p0.159
RPS3Rps3p0.151
SSA1Ssa1p0.144
RPS7ARps7ap0.131
RPT6Rpt6p0.129
RPL10Rpl10p0.127
MSH2Msh2p0.103
HTB1Htb1p0.101
KAR2Kar2p0.099
SSE1Sse1p0.089
CCT2Cct2p0.089
TOR1Tor1p0.081
MSH3Msh3p0.080
OYE2Oye2p0.079
HYP2Hyp2p0.077
DSK2Dsk2p0.074
TEF4Tef4p0.066
CCR4Ccr4p0.064
RPL13ARpl13ap0.061
AQY2Aqy2p0.060
PIL1Pil1p0.059
SNF5Snf5p0.058
ARB1Arb1p0.057
ASC1Asc1p0.057
RAD54Rad54p0.056
TDH2Tdh2p0.056
PPH22Pph22p0.055
MRT4Mrt4p0.054
KSS1Kss1p0.054
TIF5Tif5p0.051
RPN12Rpn12p0.051
SOD2Sod2p0.051
CCT6Cct6p0.051
MYO5Myo5p0.050
RPS1BRps1bp0.049
UBP9Ubp9p0.047
RPS5Rps5p0.047
RPS6BRps6bp0.047
RPL25Rpl25p0.046
PET9Pet9p0.045
DCS2Dcs2p0.045
STI1Sti1p0.044
AAC3Aac3p0.044
RPL16BRpl16bp0.044
PBS2Pbs2p0.044
MSN5Msn5p0.044
SSA3Ssa3p0.043
CDC28Cdc28p0.043
TEF1Tef1p0.041
CDC37Cdc37p0.041
CDC55Cdc55p0.038
BMH1Bmh1p0.038
OTU1Otu1p0.038
ECM29Ecm29p0.038
RPL1ARpl1ap0.037
RPP2BRpp2bp0.037
BEM1Bem1p0.036
STE5Ste5p0.036
BFR1Bfr1p0.035
IDH2Idh2p0.035
TSC11Tsc11p0.035
PPH3Pph3p0.034
SBA1Sba1p0.033
RPT1Rpt1p0.033
ALD6Ald6p0.033
PEP3Pep3p0.033
SAP1Sap1p0.033
RAD23Rad23p0.032
PKH2Pkh2p0.032
CDC53Cdc53p0.031
RPT3Rpt3p0.031
CTI6Cti6p0.031
RPS7BRps7bp0.031
RAM1Ram1p0.031
VID28Vid28p0.030
STE2Ste2p0.030
ADR1Adr1p0.030
QCR7Qcr7p0.029
PRT1Prt1p0.029
RPS6ARps6ap0.029
SSL1Ssl1p0.029
MKS1Mks1p0.029
MSG5Msg5p0.029
FCF1Fcf1p0.029
VPS29Vps29p0.029
NUP49Nup49p0.029
SGV1Sgv1p0.029
FLC1Flc1p0.028
CCS1Ccs1p0.028
CCP1Ccp1p0.028
PEP4Pep4p0.028
MKT1Mkt1p0.028
CCT3Cct3p0.028
PRE10Pre10p0.028
RPL21ARpl21ap0.027
NEO1Neo1p0.027
RAD3Rad3p0.027
ENO1Eno1p0.027