The network for 'cell development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cell development

The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.

NameDescriptionProbabilityFunc Analog Organism
goa-1Protein GOA-10.967
hlh-2Protein HLH-20.963
egl-18Protein EGL-180.948
egl-46Protein EGL-460.904
vab-3Protein VAB-30.891
dnc-2Protein DNC-20.852
egl-15Protein EGL-150.849
unc-53Protein UNC-530.843
glp-1Protein GLP-10.836
unc-6Protein UNC-60.821
unc-52Protein UNC-520.812
sax-3Protein SAX-30.800
prp-8Protein PRP-80.784
ceh-20Protein CEH-200.778
unc-73Protein UNC-730.777
lin-12Protein LIN-120.759
hcp-3Protein HCP-30.739
sma-6Protein SMA-60.727
unc-62Protein UNC-620.720
pry-1Protein PRY-10.706
sli-1Protein SLI-10.705
egl-8Protein EGL-80.701
egg-6Protein EGG-60.697
pan-1Protein PAN-10.690
pkg-1Protein PKG-10.684
elt-6Protein ELT-60.681
snr-5Protein SNR-50.680
C11E4.6Protein C11E4.60.677
sur-6Protein SUR-60.675
ect-2Protein ECT-20.674
unc-104Protein UNC-1040.653
pha-4Protein PHA-40.652
sem-5Protein SEM-50.642
egl-13Protein EGL-130.640
nap-1Protein NAP-10.627
rpa-1Protein RPA-10.626
par-5Protein PAR-50.610
mel-28Protein MEL-280.601
vbh-1Protein VBH-10.601
mom-2Protein MOM-20.593
skr-2Protein SKR-20.593
let-60Protein LET-600.591
mab-5Protein MAB-50.590
hbl-1Protein HBL-10.578
ife-1Protein IFE-10.578
egl-30Protein EGL-300.570
ajm-1Protein AJM-10.570
lrp-2Protein LRP-20.568
unc-9Protein UNC-90.562
csn-1Protein CSN-10.558
npp-1Protein NPP-10.556
cam-1Protein CAM-10.555
vha-8Protein VHA-80.554
mes-3Protein MES-30.554
scc-1Protein SCC-10.553
cin-4Protein CIN-40.549
CELE_F02E9.1Protein F02E9.10.549
egg-1Protein EGG-10.546
mbk-2Protein MBK-20.543
sma-1Protein SMA-10.543
pmk-1Protein PMK-10.541
lin-11Protein LIN-110.532
ran-1Protein RAN-10.518
ncr-1Protein NCR-10.516
cbd-1Protein CBD-10.514
pdfr-1Protein PDFR-10.512
mei-1Protein MEI-10.510
cpg-2Protein CPG-20.510
pat-12Protein PAT-120.508
daf-11Protein DAF-110.507
akt-2Protein AKT-20.507
eps-8Protein EPS-80.500
dao-5Protein DAO-50.497
pes-7Protein PES-70.496
epi-1Protein EPI-10.496
nlg-1Protein NLG-10.490
unc-60Protein UNC-600.489
egl-5Protein EGL-50.488
ppp-1Protein PPP-10.488
CELE_C23G10.8Protein C23G10.80.486
flt-1Protein FLT-10.483
myo-3Protein MYO-30.483
unc-32Protein UNC-320.478
met-2Protein MET-20.478
sec-24.2Protein SEC-24.20.478
unc-42Protein UNC-420.478
atn-1Protein ATN-10.477
rfc-2Protein RFC-20.476
daf-4Protein DAF-40.476
smp-1Protein SMP-10.475
ten-1Protein TEN-10.475
hlh-1Protein HLH-10.474
brp-1Protein BRP-10.473
npp-4Protein NPP-40.473
smu-2Protein SMU-20.472
unc-43Protein UNC-430.470
mex-5Protein MEX-50.470
bar-1Protein BAR-10.470
dsh-2Protein DSH-20.466
vab-1Protein VAB-10.460
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide1.000
EGFRepidermal growth factor receptor1.000
GRB2growth factor receptor-bound protein 21.000
CDC42cell division cycle 42 (GTP binding protein, 25kDa)1.000
ESR1estrogen receptor 11.000
TP53tumor protein p531.000
ATXN1ataxin 11.000
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)1.000
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence1.000
FYNFYN oncogene related to SRC, FGR, YES1.000
FLNAfilamin A, alpha1.000
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide1.000
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide1.000
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide1.000
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)1.000
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.999
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.999
QKIquaking homolog, KH domain RNA binding (mouse)0.999
HNRNPKheterogeneous nuclear ribonucleoprotein K0.999
FN1fibronectin 10.999
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.998
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.998
EP300E1A binding protein p3000.997
SMAD3SMAD family member 30.997
RB1retinoblastoma 10.996
CREBBPCREB binding protein0.996
JUNjun proto-oncogene0.995
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.995
NCOR1nuclear receptor corepressor 10.994
CSNK2A1casein kinase 2, alpha 1 polypeptide0.994
ITSN1intersectin 1 (SH3 domain protein)0.993
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.992
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.991
SHC1SHC (Src homology 2 domain containing) transforming protein 10.991
MAPTmicrotubule-associated protein tau0.991
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.991
HDAC1histone deacetylase 10.991
ZYXzyxin0.990
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.989
NCOR2nuclear receptor corepressor 20.989
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.989
PTPN1protein tyrosine phosphatase, non-receptor type 10.988
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.988
MAPK8mitogen-activated protein kinase 80.986
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.986
SFNstratifin0.986
ATN1atrophin 10.985
MDM2Mdm2 p53 binding protein homolog (mouse)0.985
LCKlymphocyte-specific protein tyrosine kinase0.984
VIMvimentin0.984
FHL2four and a half LIM domains 20.983
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.983
AKT1v-akt murine thymoma viral oncogene homolog 10.983
SP1Sp1 transcription factor0.982
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.982
KHDRBS1KH domain containing, RNA binding, signal transduction associated 10.982
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.981
PTPN11protein tyrosine phosphatase, non-receptor type 110.981
GAS7growth arrest-specific 70.980
UBCubiquitin C0.978
CDK2cyclin-dependent kinase 20.977
TJP1tight junction protein 1 (zona occludens 1)0.972
EEDembryonic ectoderm development0.971
BCAR1breast cancer anti-estrogen resistance 10.969
HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)0.966
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.964
FOSFBJ murine osteosarcoma viral oncogene homolog0.961
SOS1son of sevenless homolog 1 (Drosophila)0.961
HDAC2histone deacetylase 20.960
LRRK2leucine-rich repeat kinase 20.957
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.956
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.956
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.955
ACTN1actinin, alpha 10.955
PABPC1poly(A) binding protein, cytoplasmic 10.952
RBPMSRNA binding protein with multiple splicing0.951
FGFR1fibroblast growth factor receptor 10.948
CAV1caveolin 1, caveolae protein, 22kDa0.948
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.947
NCK1NCK adaptor protein 10.945
ACTBactin, beta0.943
GSK3Bglycogen synthase kinase 3 beta0.943
IGF1Rinsulin-like growth factor 1 receptor0.939
RPA1replication protein A1, 70kDa0.934
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.934
PCGF2polycomb group ring finger 20.932
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.928
JAG1jagged 10.924
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.924
SRSF3serine/arginine-rich splicing factor 30.924
HDAC4histone deacetylase 40.924
ILKintegrin-linked kinase0.921
MYH9myosin, heavy chain 9, non-muscle0.921
PKM2pyruvate kinase, muscle0.920
SMURF2SMAD specific E3 ubiquitin protein ligase 20.919
RAD21RAD21 homolog (S. pombe)0.917
ATF3activating transcription factor 30.916
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.914
APPamyloid beta (A4) precursor protein0.913
PLCG1phospholipase C, gamma 10.913
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
SPO21Spo21p0.977
ADY3Ady3p0.950
GIP1Gip1p0.944
RAS2Ras2p0.916
SPS22Sps22p0.852
MPC54Mpc54p0.803
DIT2Dit2p0.677
IRA1Ira1p0.644
SMK1Smk1p0.610
FKS3Fks3p0.609
MSN2Msn2p0.586
BMH2Bmh2p0.572
DIT1Dit1p0.571
OSW2Osw2p0.522
PCK1Pck1p0.505
CRR1Crr1p0.503
SPR3Spr3p0.470
OSW1Osw1p0.447
DTR1Dtr1p0.447
AQY2Aqy2p0.421
SPO71Spo71p0.411
LAP4Lap4p0.407
POG1Pog1p0.401
SHE4She4p0.355
SPS1Sps1p0.349
SMA2Sma2p0.344
GSC2Gsc2p0.329
PDR10Pdr10p0.308
ARC35Arc35p0.305
NKP2Nkp2p0.304
SSP1Ssp1p0.294
CAT8Cat8p0.293
RIM15Rim15p0.290
PPH21Pph21p0.288
RGS2Rgs2p0.278
RIM101Rim101p0.277
CMD1Cmd1p0.277
MIG3Mig3p0.276
YPT1Ypt1p0.272
MIG2Mig2p0.270
ECM8Ecm8p0.265
AMA1Ama1p0.261
SEC9Sec9p0.258
DON1Don1p0.252
NOP13Nop13p0.245
SSO1Sso1p0.240
MSO1Mso1p0.239
SRL4Srl4p0.232
ROX1Rox1p0.231
SNC2Snc2p0.225
CDC6Cdc6p0.209
CWP2Cwp2p0.205
CDA2Cda2p0.204
RRT12Rrt12p0.203
CYR1Cyr1p0.201
MYO5Myo5p0.201
YSW1Ysw1p0.201
GIS1Gis1p0.191
CDC25Cdc25p0.189
SPO74Spo74p0.187
GID8Gid8p0.186
VID24Vid24p0.178
SPR28Spr28p0.177
CBK1Cbk1p0.175
VPS27Vps27p0.172
YHR140Whypothetical protein0.171
YFR012Whypothetical protein0.166
NPR2Npr2p0.155
SPO77Spo77p0.155
GAS2Gas2p0.154
GPI1Gpi1p0.152
MLC1Mlc1p0.150
PET494Pet494p0.148
PKH2Pkh2p0.147
IRC10Irc10p0.146
THI11Thi11p0.145
PPZ1Ppz1p0.142
SAP155Sap155p0.139
GAS4Gas4p0.139
CMK1Cmk1p0.139
TAO3Tao3p0.137
LOH1Loh1p0.137
EAF1Eaf1p0.137
LYS5Lys5p0.136
DFG16Dfg16p0.135
TPO2Tpo2p0.135
AFT1Aft1p0.134
HXT10Hxt10p0.133
YPK2Ypk2p0.132
RTT109Rtt109p0.130
SPS2Sps2p0.129
SWF1Swf1p0.129
SPO19Spo19p0.128
YGL230Chypothetical protein0.128
YPL014Whypothetical protein0.127
ATG7Atg7p0.127
BUD4Bud4p0.126
YKR075Chypothetical protein0.126
NRG1Nrg1p0.125
ICL1Icl1p0.125