The network for 'muscle organ morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

muscle organ morphogenesis

The process in which the anatomical structures of muscle are generated and organized.

NameDescriptionProbabilityFunc Analog Organism
hlh-1Protein HLH-10.526
T21B6.3Protein T21B6.30.521
C53C9.2Protein C53C9.20.496
myo-3Protein MYO-30.482
ifb-2Protein IFB-20.467
mup-2Protein MUP-20.419
egl-18Protein EGL-180.397
ZC449.5Protein ZC449.50.377
hsp-12.2Protein HSP-12.20.339
zyx-1Protein ZYX-10.335
lev-11Protein LEV-110.315
tni-1Protein TNI-10.312
sel-8Protein SEL-80.301
ttm-4Protein TTM-40.270
tnt-2Protein TNT-20.268
gmeb-1Protein GMEB-10.258
set-18Protein SET-180.249
mig-6Protein MIG-60.233
pat-2Protein PAT-20.227
unc-27Protein UNC-270.225
dim-1Protein DIM-10.217
unc-112Protein UNC-1120.213
T25F10.6Protein T25F10.60.207
elt-6Protein ELT-60.196
fkh-2Protein FKH-20.195
ketn-1Protein KETN-10.194
ptp-1Protein PTP-10.188
ifb-1Protein IFB-10.183
T12D8.9Protein T12D8.90.180
amx-2Protein AMX-20.177
lec-3Protein LEC-30.165
cdf-1Protein CDF-10.161
ifa-1Protein IFA-10.159
nhr-67Protein NHR-670.150
let-268Protein LET-2680.143
let-2Protein LET-20.140
ifd-1Protein IFD-10.132
pat-12Protein PAT-120.126
pat-10Protein PAT-100.126
lec-2Protein LEC-20.125
pha-4Protein PHA-40.120
egl-5Protein EGL-50.118
F57B7.2Protein F57B7.20.118
unc-87Protein UNC-870.116
C54E4.2Protein C54E4.20.115
sel-12Protein SEL-120.112
ahr-1Protein AHR-10.111
epi-1Protein EPI-10.108
C11E4.1Protein C11E4.10.104
col-43Protein COL-430.101
hlh-14Protein HLH-140.101
phy-2Protein PHY-20.100
F21C10.7Protein F21C10.70.100
F33H2.3Protein F33H2.30.099
CELE_C44C10.9Protein C44C10.90.097
tnc-2Protein TNC-20.095
T03G6.3Protein T03G6.30.093
CELE_R02D3.1Protein R02D3.10.093
let-60Protein LET-600.092
M02D8.1Protein M02D8.10.088
ogt-1Protein OGT-10.087
C03A3.1Protein C03A3.10.087
unc-98Protein UNC-980.087
nucb-1Protein NUCB-10.085
mlc-2Protein MLC-20.085
unc-120Protein UNC-1200.084
cpn-3Protein CPN-30.083
K03E5.2Protein K03E5.20.083
Y102A11A.6Protein Y102A11A.60.083
inx-13Protein INX-130.080
unc-95Protein UNC-950.079
pxd-1Protein PXD-10.077
T23E7.2Protein T23E7.20.076
lin-12Protein LIN-120.076
CELE_Y64G10A.7Protein Y64G10A.70.075
F26E4.3Protein F26E4.30.074
pmt-2Protein PMT-20.074
CELE_T13H5.1Protein T13H5.10.074
nhr-20Protein NHR-200.073
gex-3Protein GEX-30.072
irx-1Protein IRX-10.071
vha-12Protein VHA-120.071
ceh-18Protein CEH-180.068
CELE_Y45F10B.13Protein Y45F10B.130.068
unc-6Protein UNC-60.067
attf-4Protein ATTF-40.066
klp-3Protein KLP-30.066
cdh-9Protein CDH-90.065
unc-15Protein UNC-150.065
magu-2Protein MAGU-20.065
unc-52Protein UNC-520.064
agr-1Protein AGR-10.064
CELE_F54D5.15Protein F54D5.150.063
Y22D7AL.15Protein Y22D7AL.150.062
col-34Protein COL-340.062
mkk-4Protein MKK-40.062
F13C5.5Protein F13C5.50.062
egl-26Protein EGL-260.061
nhr-10Protein NHR-100.060
ifd-2Protein IFD-20.059
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
myod1myogenic differentiation 10.934
bmp4bone morphogenetic protein 40.794
tbx1T-box 10.479
tal1T-cell acute lymphocytic leukemia 10.430
kdrlkinase insert domain receptor like0.218
tnni1altroponin I, skeletal, slow like0.200
smyhc2slow myosin heavy chain 20.162
gata5GATA-binding protein 50.161
unc45bunc-45 homolog B (C. elegans)0.143
aldh1a2aldehyde dehydrogenase 1 family, member A20.130
myf5myogenic factor 50.127
alcambactivated leukocyte cell adhesion molecule b0.120
etv2ets variant gene 20.106
hey2hairy/enhancer-of-split related with YRPW motif 20.105
tnni2a.4troponin I, skeletal, fast 2a.40.102
smyhc1lslow myosin heavy chain 1, like0.100
wlswntless homolog (Drosophila)0.097
wnt2bbwingless-type MMTV integration site family, member 2Bb0.096
smyd1bSET and MYND domain containing 1b0.094
ttnatitin a0.086
tbx5aT-box 5a0.079
rbm24aRNA binding motif protein 24a0.079
wnt11rwingless-type MMTV integration site family, member 11, related0.067
hhexhematopoietically expressed homeobox0.062
smyhc1slow myosin heavy chain 10.057
alcamaactivated leukocyte cell adhesion molecule a0.057
pea3ETS-domain transcription factor pea30.056
tnnc1btroponin C type 1b (slow)0.056
tbx18T-box 180.054
wnt5bwingless-type MMTV integration site family, member 5b0.052
actc1bactin, alpha, cardiac muscle 1b0.049
sh3gl1bSH3-domain GRB2-like 1b0.049
crxcone-rod homeobox0.047
cmlc1cardiac myosin light chain-10.047
aplnrbapelin receptor b0.045
crb2acrumbs homolog 2a0.043
bmp2bbone morphogenetic protein 2b0.042
cx39.9connexin 39.90.042
actc1aactin, alpha, cardiac muscle 1a0.039
pitx2paired-like homeodomain transcription factor 20.038
ttnbtitin b0.038
tnnc2troponin C type 2 (fast)0.037
col9a2procollagen, type IX, alpha 20.036
foxc1aforkhead box C1a0.036
myl7myosin, light polypeptide 7, regulatory0.033
hspb1heat shock protein, alpha-crystallin-related, 10.033
slc8a1asolute carrier family 8 (sodium/calcium exchanger), member 1a0.033
myhz1.2myosin, heavy polypeptide 1.2, skeletal muscle0.033
mef2camyocyte enhancer factor 2ca0.033
tp53bp2tumor protein p53 binding protein, 20.033
cdh2cadherin 2, neuronal0.032
mylz2myosin, light polypeptide 2, skeletal muscle0.031
nkx2.5NK2 transcription factor related 50.030
pdlim7PDZ and LIM domain 70.029
prrx1apaired related homeobox 1a0.028
myl1myosin, light chain 1, alkali; skeletal, fast0.027
ptprjaprotein tyrosine phosphatase, receptor type, J a0.026
plcg1phospholipase C, gamma 10.025
fstl1bfollistatin-like 1b0.025
actn3bactinin alpha 3b0.024
hsp90a.1heat shock protein 90-alpha 10.024
notch3notch homolog 30.024
dsc2ldesmocollin 2 like0.023
rbfox1lRNA binding protein, fox-1 homolog (C. elegans) 1-like0.022
s1pr2sphingosine-1-phosphate receptor 20.021
alpialkaline phosphatase, intestinal0.021
hand2heart and neural crest derivatives expressed transcript 20.021
runx1runt-related transcription factor 10.020
tbx2bT-box 2b0.019
mef2cbmyocyte enhancer factor 2cb0.019
vegfcvascular endothelial growth factor c0.019
fli1afriend leukemia integration 1a0.018
col11a1bcollagen type XI alpha-1b and collagen, type XI, alpha 1b0.018
cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.018
xirp1xin actin-binding repeat containing 10.018
sema3aasemaphorin 3aa0.018
myhz2myosin, heavy polypeptide 2, fast muscle specific0.018
fgf4fibroblast growth factor 40.017
per3period homolog 3 (Drosophila)0.017
nppanatriuretic peptide precursor A0.017
atp2a1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.017
sox2SRY-box containing gene 20.017
tnni1btroponin I, skeletal, slow b0.017
neurodneurogenic differentiation0.017
atp2a2aATPase, Ca++ transporting, cardiac muscle, slow twitch 2a0.017
tnnt2atroponin T2a, cardiac0.016
fn1fibronectin 10.016
frem3Fras1 related extracellular matrix 30.015
vmhcventricular myosin heavy chain0.015
nfe2nuclear factor, erythroid-derived 20.015
ilf2interleukin enhancer binding factor 20.014
vsx1visual system homeobox 1 homolog, chx10-like0.014
bmp2abone morphogenetic protein 2a0.014
myf6myogenic factor 60.014
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
wupAwings up A0.615
snssticks and stones0.320
MhcMyosin heavy chain0.154
rolsrolling pebbles0.139
Mef2Myocyte enhancer factor 20.109
cicubitus interruptus0.104
slp1sloppy paired 10.103
kirrekin of irre0.082
EgfrEpidermal growth factor receptor0.081
Rya-r44FRyanodine receptor 44F0.071
kibrakibra ortholog0.053
Act88FActin 88F0.050
lbeladybird early0.045
eyaeyes absent0.042
abd-Aabdominal A0.042
Tsc1CG6147 gene product from transcript CG6147-RA0.041
Tm2Tropomyosin 20.041
nabCG33545 gene product from transcript CG33545-RC0.032
cindrCIN85 and CD2AP orthologue0.028
AP-2CG7807 gene product from transcript CG7807-RB0.025
Zasp52Z band alternatively spliced PDZ-motif protein 520.023
nkdnaked cuticle0.023
aopanterior open0.022
dcodiscs overgrown0.020
Actnalpha actinin0.019
luteCG5319 gene product from transcript CG5319-RA0.018
TomTwin of m40.018
TolloCG6890 gene product from transcript CG6890-RA0.018
RdlResistant to dieldrin0.018
sogshort gastrulation0.018
lmdlame duck0.017
highikaru genki0.017
Tm1Tropomyosin 10.017
Cg25CCollagen type IV0.016
amosabsent MD neurons and olfactory sensilla0.016
Rab11Rab-protein 110.016
rapretina aberrant in pattern0.015
nocno ocelli0.015
LanALaminin A0.015
argosCG4531 gene product from transcript CG4531-RA0.015
fasfaint sausage0.014
sosine oculis0.013
C15CG7937 gene product from transcript CG7937-RA0.012
gbbglass bottom boat0.012
Vrp1Verprolin 10.012
PoxmPox meso0.011
Ak6Adenylate kinase 60.011
vndventral nervous system defective0.011
Lim1CG11354 gene product from transcript CG11354-RA0.011
LamCLamin C0.011
pdm2POU domain protein 20.011
wbwing blister0.010
Six4CG3871 gene product from transcript CG3871-RA0.010
gcmglial cells missing0.010
numbCG3779 gene product from transcript CG3779-RB0.010
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TRIM63tripartite motif containing 630.999
TNNC1troponin C type 1 (slow)0.996
TNNI1troponin I type 1 (skeletal, slow)0.991
SMYD1SET and MYND domain containing 10.925
CSRP3cysteine and glycine-rich protein 3 (cardiac LIM protein)0.825
TPM1tropomyosin 1 (alpha)0.812
ACTA1actin, alpha 1, skeletal muscle0.783
MYH9myosin, heavy chain 9, non-muscle0.773
MYOD1myogenic differentiation 10.753
TPM2tropomyosin 2 (beta)0.625
IKIK cytokine, down-regulator of HLA II0.581
TNNT3troponin T type 3 (skeletal, fast)0.575
TNNT2troponin T type 2 (cardiac)0.548
SNW1SNW domain containing 10.545
ESR2estrogen receptor 2 (ER beta)0.535
ESR1estrogen receptor 10.525
GSK3Bglycogen synthase kinase 3 beta0.509
TBX5T-box 50.504
ACTN2actinin, alpha 20.502
CKMcreatine kinase, muscle0.492
SMAD3SMAD family member 30.469
COX6A2cytochrome c oxidase subunit VIa polypeptide 20.415
ACVR1Bactivin A receptor, type IB0.390
MYH7myosin, heavy chain 7, cardiac muscle, beta0.384
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.367
PDLIM7PDZ and LIM domain 7 (enigma)0.342
BMPR1Abone morphogenetic protein receptor, type IA0.325
EFTUD2elongation factor Tu GTP binding domain containing 20.324
TNNI2troponin I type 2 (skeletal, fast)0.310
INADLInaD-like (Drosophila)0.291
MYL2myosin, light chain 2, regulatory, cardiac, slow0.283
ATP2A1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.258
MYH1myosin, heavy chain 1, skeletal muscle, adult0.244
MYLPFmyosin light chain, phosphorylatable, fast skeletal muscle0.231
TCAPtitin-cap (telethonin)0.229
SETD8SET domain containing (lysine methyltransferase) 80.226
MYOZ1myozenin 10.223
FLNAfilamin A, alpha0.196
MYL1myosin, light chain 1, alkali; skeletal, fast0.188
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.182
SKILSKI-like oncogene0.170
MFAP1microfibrillar-associated protein 10.161
ANKRD2ankyrin repeat domain 2 (stretch responsive muscle)0.159
MYBPC2myosin binding protein C, fast type0.158
YAP1Yes-associated protein 10.155
HNF4Ahepatocyte nuclear factor 4, alpha0.152
FGF1fibroblast growth factor 1 (acidic)0.148
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.142
LDB3LIM domain binding 30.136
CTGFconnective tissue growth factor0.131
MYL3myosin, light chain 3, alkali; ventricular, skeletal, slow0.129
MYH6myosin, heavy chain 6, cardiac muscle, alpha0.124
OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF0.121
SMAD9SMAD family member 90.117
ACTN1actinin, alpha 10.116
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.114
JAG1jagged 10.114
GATA4GATA binding protein 40.113
MYBPC1myosin binding protein C, slow type0.111
ACTN3actinin, alpha 30.103
CHD3chromodomain helicase DNA binding protein 30.100
CXXC5CXXC finger protein 50.098
ZNF830zinc finger protein 8300.086
MYOGmyogenin (myogenic factor 4)0.083
MYOZ2myozenin 20.082
HAP1huntingtin-associated protein 10.081
RBFOX2RNA binding protein, fox-1 homolog (C. elegans) 20.080
IKBKEinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon0.078
SNIP1Smad nuclear interacting protein 10.077
TNNC2troponin C type 2 (fast)0.075
WNT3Awingless-type MMTV integration site family, member 3A0.070
KRT14keratin 140.068
PTPRJprotein tyrosine phosphatase, receptor type, J0.061
COL4A2collagen, type IV, alpha 20.058
CNN1calponin 1, basic, smooth muscle0.058
MYBPHmyosin binding protein H0.057
TNNI3troponin I type 3 (cardiac)0.054
TAL1T-cell acute lymphocytic leukemia 10.051
SPARCsecreted protein, acidic, cysteine-rich (osteonectin)0.051
MYL4myosin, light chain 4, alkali; atrial, embryonic0.050
MYH8myosin, heavy chain 8, skeletal muscle, perinatal0.049
PAX8paired box 80.048
TPM4tropomyosin 40.046
COL4A1collagen, type IV, alpha 10.046
FGF7fibroblast growth factor 70.044
JUPjunction plakoglobin0.041
ARPC2actin related protein 2/3 complex, subunit 2, 34kDa0.039
GATA1GATA binding protein 1 (globin transcription factor 1)0.039
MYH2myosin, heavy chain 2, skeletal muscle, adult0.038
TNNT1troponin T type 1 (skeletal, slow)0.038
HEYLhairy/enhancer-of-split related with YRPW motif-like0.037
GATA2GATA binding protein 20.037
SMPXsmall muscle protein, X-linked0.037
FOXA2forkhead box A20.037
CALD1caldesmon 10.036
EP300E1A binding protein p3000.035
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.771
Myh6myosin, heavy chain 6, cardiac muscle, alpha0.340
Col1a1collagen, type I, alpha 10.254
Actc1actin, alpha, cardiac muscle 10.254
Myh7myosin, heavy chain 7, cardiac muscle, beta0.201
Myl3myosin, light chain 3, alkali; ventricular, skeletal, slow0.173
Col5a2collagen, type V, alpha 20.157
Csrp3cysteine and glycine-rich protein 30.142
Cox6a2cytochrome c oxidase, subunit VIa, polypeptide 20.135
Ankrd1ankyrin repeat domain 1 (cardiac muscle)0.135
Myoz2myozenin 20.122
Ckmcreatine kinase, muscle0.097
Tnni3troponin I type 3 (cardiac)0.095
Mybphmyosin binding protein H0.091
Hand2heart and neural crest derivatives expressed 20.084
Gria2glutamate receptor, ionotropic, AMPA 20.082
Cacna1scalcium channel, voltage-dependent, L type, alpha 1S subunit0.082
Foxi2forkhead box I20.072
Actn2actinin alpha 20.071
Pgam2phosphoglycerate mutase 2 (muscle)0.062
Mybpc1myosin binding protein C, slow type0.059
Cox8bcytochrome c oxidase, subunit VIIIb0.057
Klk1lkallikrein 1-like peptidase0.055
Myl9myosin, light chain 9, regulatory0.053
Casq2calsequestrin 2 (cardiac muscle)0.042
Crybb3crystallin, beta B30.040
Nfyanuclear transcription factor-Y alpha0.039
Eif4heukaryotic translation initiation factor 4H0.036
Cav3caveolin 30.034
Sdc3syndecan 30.034
Wipf3WAS/WASL interacting protein family, member 30.033
Neurog1neurogenin 10.032
Foxd3forkhead box D30.032
Col1a2collagen, type I, alpha 20.032
Myh1myosin, heavy polypeptide 1, skeletal muscle, adult0.031
Hspb2heat shock protein beta 20.031
Tnni1troponin I type 1 (skeletal, slow)0.031
Gria3glutamate receptor, ionotrophic, AMPA 30.031
RGD1562525similar to cell surface receptor FDFACT0.030
Myom1myomesin 10.030
Alx1ALX homeobox 10.030
Mylpfmyosin light chain, phosphorylatable, fast skeletal muscle0.029
Ube2l3ubiquitin-conjugating enzyme E2L 30.029
Acta1actin, alpha 1, skeletal muscle0.029
Kcnj5potassium inwardly-rectifying channel, subfamily J, member 50.029
Acta2smooth muscle alpha-actin0.028
Hoxc4homeo box C40.027
Tnni2troponin I type 2 (skeletal, fast)0.027
Ckmt2creatine kinase, mitochondrial 2, sarcomeric0.027
Dchs1dachsous 1 (Drosophila)0.027
Loxl1lysyl oxidase-like 10.026
Ccnd1cyclin D10.026
Col5a1collagen, type V, alpha 10.026
Rgrretinal G protein coupled receptor0.026
Msmbmicroseminoprotein, beta0.026
Fgf16fibroblast growth factor 160.025
Rab2aRAB2A, member RAS oncogene family0.025
Snai2snail homolog 2 (Drosophila)0.025
Srmspermidine synthase0.025
Arf1ADP-ribosylation factor 10.024
Pick1protein interacting with PRKCA 10.024
Flnafilamin A, alpha0.023
Hoxa1homeo box A10.023
Cyp24a1cytochrome P450, family 24, subfamily a, polypeptide 10.023
P2rx5purinergic receptor P2X, ligand-gated ion channel, 50.023
Tnnt2troponin T type 2 (cardiac)0.023
Tpm1tropomyosin 1, alpha0.023
Klk1c10l2kallikrein 1-related peptidase c10-like 20.023
Oprd1opioid receptor, delta 10.022
Dhrs7cdehydrogenase/reductase (SDR family) member 7C0.022
Myl1myosin, light chain 10.022
Art1ADP-ribosyltransferase 10.022
Fgf18fibroblast growth factor 180.021
Tpothyroid peroxidase0.021
Lims1LIM and senescent cell antigen-like domains 10.021
Zfp706zinc finger protein 7060.021
Igf2insulin-like growth factor 20.020
Bdkrb2bradykinin receptor B20.020
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.020
Slc12a4solute carrier family 12 (potassium/chloride transporters), member 40.020
Hoxb7homeo box B70.020
Myh8myosin, heavy chain 8, skeletal muscle, perinatal0.020
Grm8glutamate receptor, metabotropic 80.019
Hist1h1dhistone cluster 1, H1d0.019
Nr5a1nuclear receptor subfamily 5, group A, member 10.019
Pdgfbplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.019
Ppfia4protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 40.019
Acox2acyl-Coenzyme A oxidase 2, branched chain0.019
Hes5hairy and enhancer of split 5 (Drosophila)0.019
Myl7myosin, light chain 7, regulatory0.019
Plrg1pleiotropic regulator 1, PRL1 homolog (Arabidopsis)0.019
Tubb5tubulin, beta 50.019
Ptgirprostaglandin I2 (prostacyclin) receptor (IP)0.019
Cited1Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 10.019
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism