The network for 'regulation of gene expression' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of gene expression

Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.

NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.954
vab-3Protein VAB-30.943
lin-35Protein LIN-350.935
pha-4Protein PHA-40.925
elt-6Protein ELT-60.850
unc-37Protein UNC-370.823
rsp-1Protein RSP-10.821
eya-1Protein EYA-10.813
lmn-1Protein LMN-10.804
nhr-49Protein NHR-490.791
ceh-20Protein CEH-200.788
unc-43Protein UNC-430.784
cacn-1Protein CACN-10.783
R186.7Protein R186.70.781
D1081.8Protein D1081.80.776
nhr-67Protein NHR-670.768
his-45Protein HIS-450.743
bet-1Protein BET-10.735
unc-62Protein UNC-620.723
attf-2Protein ATTF-20.713
mdf-2Protein MDF-20.710
ubr-1Protein UBR-10.708
mep-1Protein MEP-10.707
sas-5Protein SAS-50.704
rnp-6Protein RNP-60.703
npp-4Protein NPP-40.701
egl-46Protein EGL-460.689
patr-1Protein PATR-10.681
egl-13Protein EGL-130.671
egl-27Protein EGL-270.668
lin-36Protein LIN-360.664
aap-1Protein AAP-10.648
hcp-3Protein HCP-30.646
htz-1Protein HTZ-10.638
glp-1Protein GLP-10.637
cfim-2Protein CFIM-20.620
nhr-2Protein NHR-20.613
F39B2.1Protein F39B2.10.595
skp-1Protein SKP-10.592
cpg-2Protein CPG-20.589
zyg-1Protein ZYG-10.587
abl-1Protein ABL-10.587
hbl-1Protein HBL-10.586
fkh-2Protein FKH-20.585
nhr-69Protein NHR-690.585
jmjd-2Protein JMJD-20.583
egl-8Protein EGL-80.581
let-502Protein LET-5020.577
scc-1Protein SCC-10.575
smp-1Protein SMP-10.569
C30F12.4Protein C30F12.40.568
unc-52Protein UNC-520.568
pry-1Protein PRY-10.561
klp-16Protein KLP-160.546
lsm-5Protein LSM-50.539
bra-2Protein BRA-20.532
hlh-2Protein HLH-20.532
hmg-1.2Protein HMG-1.20.528
mut-16Protein MUT-160.527
nhr-25Protein NHR-250.526
hmg-4Protein HMG-40.525
svh-2Protein SVH-20.521
eat-6Protein EAT-60.516
CELE_C17E4.6Protein C17E4.60.511
mdf-1Protein MDF-10.509
lsy-22Protein LSY-220.508
his-31Protein HIS-310.503
eef-1A.1Protein EEF-1A.10.503
peb-1Protein PEB-10.502
brc-1Protein BRC-10.496
cpg-1Protein CPG-10.494
npp-7Protein NPP-70.493
his-3Protein HIS-30.482
lin-53Protein LIN-530.480
his-64Protein HIS-640.480
lsy-2Protein LSY-20.478
atn-1Protein ATN-10.477
his-61Protein HIS-610.476
npp-1Protein NPP-10.473
lin-40Protein LIN-400.473
mig-5Protein MIG-50.471
gop-2Protein GOP-20.467
mcm-4Protein MCM-40.466
rpn-2Protein RPN-20.462
hrp-1Protein HRP-10.459
F33D11.10Protein F33D11.100.457
F21A10.2Protein F21A10.20.457
cnd-1Protein CND-10.448
sma-6Protein SMA-60.446
hum-5Protein HUM-50.443
gon-4Protein GON-40.433
aly-3Protein ALY-30.432
dlk-1Protein DLK-10.431
Y44E3A.6Protein Y44E3A.60.430
F08B4.7Protein F08B4.70.429
zip-7Protein ZIP-70.428
CELE_F52C6.3Protein F52C6.30.427
CELE_C16C10.4Protein C16C10.40.423
his-48Protein HIS-480.423
lin-66Protein LIN-660.423
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
gli1GLI-Kruppel family member 10.999
dladeltaA0.997
fgf3fibroblast growth factor 30.997
notch1anotch homolog 1a0.996
shhasonic hedgehog a0.996
gata6GATA-binding protein 60.995
gata3GATA-binding protein 30.993
foxa2forkhead box A20.991
ntlano tail a0.991
pax2apaired box gene 2a0.989
otx2orthodenticle homolog 20.986
tp53tumor protein p530.986
lhx1aLIM homeobox 1a0.984
pitx3paired-like homeodomain transcription factor 30.984
wnt2bbwingless-type MMTV integration site family, member 2Bb0.983
fgfr1afibroblast growth factor receptor 1a0.983
flhfloating head0.977
nkx2.2aNK2 transcription factor related 2a0.977
bmp2bbone morphogenetic protein 2b0.974
egr1early growth response 10.972
eomesaeomesodermin homolog a0.969
pax6apaired box gene 6a0.969
ephb4beph receptor B4b0.968
foxa3forkhead box A30.968
evx1even-skipped homeobox 10.966
olfm2olfactomedin 20.964
chdchordin0.961
lef1lymphocyte enhancer binding factor 10.958
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.955
tal1T-cell acute lymphocytic leukemia 10.954
pax8paired box gene 80.948
runx2brunt-related transcription factor 2b0.947
pcdh18bprotocadherin 18b0.944
myod1myogenic differentiation 10.938
cdh1cadherin 1, epithelial0.934
six1bsine oculis homeobox homolog 1b0.933
dlx5adistal-less homeobox gene 5a0.932
pcnaproliferating cell nuclear antigen0.924
spry4sprouty (Drosophila) homolog 40.916
fezf2FEZ family zinc finger 20.916
crestincrestin0.914
dmbx1adiencephalon/mesencephalon homeobox 1a0.910
atoh1aatonal homolog 1a0.910
sox2SRY-box containing gene 20.909
lmx1b.1LIM homeobox transcription factor 1, beta 10.906
snai1bsnail homolog 1b (Drosophila)0.904
sesn1sestrin 10.903
nr2e1nuclear receptor subfamily 2, group E, member 10.901
klf4Kruppel-like factor 40.901
tgif1TGFB-induced factor homeobox 10.897
tfap2atranscription factor AP-2 alpha0.891
ef1aelongation factor 1-alpha0.890
eya1eyes absent homolog 10.890
myhz2myosin, heavy polypeptide 2, fast muscle specific0.888
plp1aproteolipid protein 1a0.887
mef2dmyocyte enhancer factor 2d0.886
neurodneurogenic differentiation0.881
tcf7l1atranscription factor 7-like 1a (T-cell specific, HMG-box)0.881
otx1borthodenticle homolog 1b0.875
pitx2paired-like homeodomain transcription factor 20.875
cdx4caudal type homeo box transcription factor 40.871
rx3retinal homeobox gene 30.866
oprd1bopioid receptor, delta 1b0.866
ptf1apancreas specific transcription factor, 1a0.864
lft1lefty10.860
otpborthopedia homolog b0.854
nkx2.5NK2 transcription factor related 50.851
mapk1mitogen-activated protein kinase 10.847
zic1zic family member 1 (odd-paired homolog, Drosophila)0.846
mstnbmyostatin b0.843
rasl11bRAS-like, family 11, member B0.834
tfap2btranscription factor AP-2 beta0.834
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.828
sall1asal-like 1a (Drosophila)0.826
gata5GATA-binding protein 50.822
osr1odd-skipped related 1 (Drosophila)0.821
tardbpTAR DNA binding protein0.819
hhiphedgehog interacting protein0.818
dkk1bdickkopf 1b0.817
foxp2forkhead box P20.809
fgf8afibroblast growth factor 8 a0.808
sox19bSRY-box containing gene 19b0.807
wnt11wingless-type MMTV integration site family, member 110.805
ndr2nodal-related 20.801
tbx18T-box 180.801
dlx3bdistal-less homeobox gene 3b0.800
msxemuscle segment homeobox E0.793
oepone-eyed pinhead0.789
rad21RAD21 homolog (S. pombe)0.778
jag2jagged 20.776
mespamesoderm posterior a0.774
tgfb3transforming growth factor, beta 30.774
fzd7afrizzled homolog 7a0.774
sox19aSRY-box containing gene 19a0.769
fli1afriend leukemia integration 1a0.767
smad5MAD homolog 5 (Drosophila)0.757
hoxb1bhomeo box B1b0.753
wnt10awingless-type MMTV integration site family, member 10a0.753
neurog1neurogenin 10.752
nclnucleolin0.751
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism