The network for 'male germ line sex determination' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

male germ line sex determination

The determination of sex and sexual phenotype in a male organism's germ line.

NameDescriptionProbabilityFunc Analog Organism
hlh-1Protein HLH-10.121
elt-6Protein ELT-60.110
egl-18Protein EGL-180.078
hnd-1Protein HND-10.075
cnd-1Protein CND-10.046
fkh-2Protein FKH-20.035
ten-1Protein TEN-10.034
nhr-67Protein NHR-670.030
egl-46Protein EGL-460.029
hlh-14Protein HLH-140.022
irx-1Protein IRX-10.021
ceh-13Protein CEH-130.016
mon-2Protein MON-20.015
unc-62Protein UNC-620.014
sma-9Protein SMA-90.014
K10C3.5Protein K10C3.50.011
nab-1Protein NAB-10.011
F43D9.1Protein F43D9.10.011
pqn-73Protein PQN-730.011
vab-3Protein VAB-30.011
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Meox2mesenchyme homeobox 20.809
Gli3GLI-Kruppel family member GLI30.735
Shesrc homology 2 domain-containing transforming protein E0.727
Emx1empty spiracles homolog 1 (Drosophila)0.479
Pax3paired box gene 30.455
Fgfr2fibroblast growth factor receptor 20.393
Sox17SRY-box containing gene 170.365
Sox11SRY-box containing gene 110.362
Cldn5claudin 50.286
Shhsonic hedgehog0.244
Nf1neurofibromatosis 10.234
Hes1hairy and enhancer of split 1 (Drosophila)0.212
Lrp2low density lipoprotein receptor-related protein 20.207
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.203
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.165
Pou5f1POU domain, class 5, transcription factor 10.151
Xpo4exportin 40.147
Col2a1collagen, type II, alpha 10.121
Aplnrapelin receptor0.120
Sox4SRY-box containing gene 40.115
Icam2intercellular adhesion molecule 20.112
Gata3GATA binding protein 30.111
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.107
Fgf8fibroblast growth factor 80.105
Kitkit oncogene0.099
Sfrp2secreted frizzled-related protein 20.097
Sox18SRY-box containing gene 180.095
Ednrbendothelin receptor type B0.089
Tcfap2atranscription factor AP-2, alpha0.087
Rarbretinoic acid receptor, beta0.086
Fgf10fibroblast growth factor 100.083
Sox7SRY-box containing gene 70.081
Gja4gap junction protein, alpha 40.080
Meox1mesenchyme homeobox 10.078
Kitlkit ligand0.077
Itgb1integrin beta 1 (fibronectin receptor beta)0.077
Ikbkapinhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein0.077
Sall3sal-like 3 (Drosophila)0.075
Sox2SRY-box containing gene 20.072
Bmp4bone morphogenetic protein 40.071
Sin3atranscriptional regulator, SIN3A (yeast)0.070
Pax6paired box gene 60.070
Bcl6bB-cell CLL/lymphoma 6, member B0.069
Isl1ISL1 transcription factor, LIM/homeodomain0.069
Cux1cut-like homeobox 10.067
Rasip1Ras interacting protein 10.064
Hhexhematopoietically expressed homeobox0.062
Gli2GLI-Kruppel family member GLI20.061
NanogNanog homeobox0.057
Ptprbprotein tyrosine phosphatase, receptor type, B0.056
Esamendothelial cell-specific adhesion molecule0.055
Sall4sal-like 4 (Drosophila)0.055
Kdrkinase insert domain protein receptor0.053
Insm1insulinoma-associated 10.053
Tgfb2transforming growth factor, beta 20.049
Pitx1paired-like homeodomain transcription factor 10.046
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.046
Apcadenomatosis polyposis coli0.045
Mitfmicrophthalmia-associated transcription factor0.045
Tbx2T-box 20.044
Hey1hairy/enhancer-of-split related with YRPW motif 10.042
Hoxa5homeobox A50.042
Retret proto-oncogene0.039
Alx4aristaless-like homeobox 40.038
Hes5hairy and enhancer of split 5 (Drosophila)0.037
Hesx1homeobox gene expressed in ES cells0.036
Tekendothelial-specific receptor tyrosine kinase0.036
Fgf4fibroblast growth factor 40.036
Flt1FMS-like tyrosine kinase 10.036
Notch3Notch gene homolog 3 (Drosophila)0.033
Tcf15transcription factor 150.033
Alx3aristaless-like homeobox 30.033
Pitx2paired-like homeodomain transcription factor 20.032
Ldb2LIM domain binding 20.031
Tcfap2ctranscription factor AP-2, gamma0.031
Robo4roundabout homolog 4 (Drosophila)0.030
Sall1sal-like 1 (Drosophila)0.029
Kcnk2potassium channel, subfamily K, member 20.028
Rb1retinoblastoma 10.027
Adcy4adenylate cyclase 40.027
Nos3nitric oxide synthase 3, endothelial cell0.026
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.026
Smad6MAD homolog 6 (Drosophila)0.026
Fgf3fibroblast growth factor 30.026
Chd7chromodomain helicase DNA binding protein 70.025
Nkx2-3NK2 transcription factor related, locus 3 (Drosophila)0.024
Nkx2-2NK2 transcription factor related, locus 2 (Drosophila)0.024
Bmp6bone morphogenetic protein 60.024
Ror2receptor tyrosine kinase-like orphan receptor 20.023
Epas1endothelial PAS domain protein 10.023
Ascl1achaete-scute complex homolog 1 (Drosophila)0.023
Pou3f1POU domain, class 3, transcription factor 10.023
Efsembryonal Fyn-associated substrate0.023
Nkx6-1NK6 homeobox 10.022
Srysex determining region of Chr Y0.022
Myl7myosin, light polypeptide 7, regulatory0.021
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism