The network for 'cytoskeleton organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.

NameDescriptionProbabilityFunc Analog Organism
atn-1Protein ATN-10.932
goa-1Protein GOA-10.923
sem-5Protein SEM-50.866
aspm-1Protein ASPM-10.812
npp-7Protein NPP-70.779
rpl-18Protein RPL-180.738
unc-40Protein UNC-400.711
unc-15Protein UNC-150.679
prp-8Protein PRP-80.670
nmy-2Protein NMY-20.667
unc-43Protein UNC-430.633
rpl-19Protein RPL-190.632
tag-232Protein TAG-2320.620
gpr-1Protein GPR-10.599
rpa-2Protein RPA-20.579
pat-3Protein PAT-30.567
npp-19Protein NPP-190.538
act-4Protein ACT-40.535
zyg-9Protein ZYG-90.524
egl-8Protein EGL-80.518
myo-3Protein MYO-30.517
myo-1Protein MYO-10.515
hcp-3Protein HCP-30.510
pkg-1Protein PKG-10.508
his-64Protein HIS-640.501
rpl-15Protein RPL-150.495
mpk-1Protein MPK-10.489
acy-1Protein ACY-10.482
CELE_C25A1.4Protein C25A1.40.478
cysl-1Protein CYSL-10.476
kgb-1Protein KGB-10.475
lag-1Protein LAG-10.467
npp-9Protein NPP-90.463
mat-3Protein MAT-30.453
cmd-1Protein CMD-10.453
lin-13Protein LIN-130.450
adr-1Protein ADR-10.446
deb-1Protein DEB-10.429
mig-2Protein MIG-20.425
insc-1Protein INSC-10.424
F33H2.3Protein F33H2.30.421
F39G3.5Protein F39G3.50.420
lin-25Protein LIN-250.413
spc-1Protein SPC-10.412
ubr-1Protein UBR-10.411
par-5Protein PAR-50.403
rpl-2Protein RPL-20.398
hsp-12.2Protein HSP-12.20.396
gsp-1Protein GSP-10.392
che-13Protein CHE-130.387
tct-1Protein TCT-10.386
cls-2Protein CLS-20.386
pch-2Protein PCH-20.386
hlh-2Protein HLH-20.385
rpa-1Protein RPA-10.384
sma-6Protein SMA-60.381
unc-16Protein UNC-160.377
let-756Protein LET-7560.375
ten-1Protein TEN-10.366
hlh-1Protein HLH-10.363
ketn-1Protein KETN-10.352
lec-1Protein LEC-10.350
slo-1Protein SLO-10.349
rpl-24.1Protein RPL-24.10.345
ess-2Protein ESS-20.344
mig-5Protein MIG-50.341
dyc-1Protein DYC-10.340
dnj-12Protein DNJ-120.340
sas-6Protein SAS-60.338
inx-12Protein INX-120.333
rps-6Protein RPS-60.333
CELE_C24H12.5Protein C24H12.50.333
crt-1Protein CRT-10.333
pfd-1Protein PFD-10.331
ced-3Protein CED-30.329
syg-1Protein SYG-10.328
rps-7Protein RPS-70.325
spd-5Protein SPD-50.324
fem-3Protein FEM-30.323
pbs-3Protein PBS-30.323
ajm-1Protein AJM-10.322
gei-4Protein GEI-40.322
T04C9.1Protein T04C9.10.317
cgh-1Protein CGH-10.310
R11A8.7Protein R11A8.70.308
his-1Protein HIS-10.307
twk-18Protein TWK-180.306
rpt-5Protein RPT-50.304
vha-8Protein VHA-80.304
mlc-3Protein MLC-30.300
acs-4Protein ACS-40.298
egl-18Protein EGL-180.295
elt-6Protein ELT-60.295
pat-4Protein PAT-40.293
R08D7.2Protein R08D7.20.287
hsr-9Protein HSR-90.286
pat-12Protein PAT-120.286
csq-1Protein CSQ-10.285
rpl-5Protein RPL-50.285
unc-45Protein UNC-450.285
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
myhz1.1myosin, heavy polypeptide 1.1, skeletal muscle0.959
ttnatitin a0.868
unc45bunc-45 homolog B (C. elegans)0.861
ptch2patched 20.854
nebnebulin0.847
shhasonic hedgehog a0.845
dag1dystroglycan 10.844
lamc1laminin, gamma 10.811
sass6spindle assembly 6 homolog (C. elegans)0.776
pdlim7PDZ and LIM domain 70.770
pak1p21/Cdc42/Rac1-activated kinase 10.745
efnb2aephrin B2a0.734
gpr126G protein-coupled receptor 1260.719
gli1GLI-Kruppel family member 10.711
lama1laminin, alpha 10.702
lamb1alaminin, beta 1a0.636
apcadenomatosis polyposis coli0.595
tnni2a.4troponin I, skeletal, fast 2a.40.583
myod1myogenic differentiation 10.568
flncbfilamin C, gamma b (actin binding protein 280)0.540
ilkintegrin linked kinase0.525
prkciprotein kinase C, iota0.506
cmybtranscription factor cmyb0.501
snrpcsmall nuclear ribonucleoprotein polypeptide C0.487
tnnc1btroponin C type 1b (slow)0.471
hsp90a.1heat shock protein 90-alpha 10.452
rpl14ribosomal protein L140.448
mfn2mitofusin 20.448
lama2laminin, alpha 20.423
rps5ribosomal protein S50.415
csadcysteine sulfinic acid decarboxylase0.415
smyd1bSET and MYND domain containing 1b0.403
desmadesmin a0.396
kpna2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.391
kif17kinesin family member 170.385
wnt2bbwingless-type MMTV integration site family, member 2Bb0.366
rps29ribosomal protein S290.365
zgc:66286zgc:662860.365
perpPERP, TP53 apoptosis effector0.361
hmgb2bhigh-mobility group box 2b0.350
spry4sprouty (Drosophila) homolog 40.344
fblfibrillarin0.328
robo2roundabout homolog 20.326
fn1fibronectin 10.324
pxnpaxillin0.314
rps11ribosomal protein S110.309
nrp1aneuropilin 1a0.306
kif23kinesin family member 230.304
tnni1btroponin I, skeletal, slow b0.300
bmp4bone morphogenetic protein 40.299
ncor1nuclear receptor co-repressor 10.298
lama5laminin, alpha 50.295
notum3notum 30.292
tpm3tropomyosin 30.291
rpsaribosomal protein SA0.288
foxj1bforkhead box J1b0.281
pdlim5PDZ and LIM domain 50.279
ndrg1N-myc downstream regulated gene 10.278
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.273
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.272
mmp2matrix metalloproteinase 20.268
lamb2laminin, beta 2 (laminin S)0.263
arpc5bactin related protein 2/3 complex, subunit 5B0.261
s100a10bS100 calcium binding protein A10b0.260
gna12guanine nucleotide binding protein (G protein) alpha 120.259
rps18ribosomal protein S180.257
cnn2calponin 20.253
eif3geukaryotic translation initiation factor 3, subunit G0.251
tnni1altroponin I, skeletal, slow like0.248
vhlvon Hippel-Lindau tumor suppressor0.245
cdh23cadherin-like 230.245
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.244
epb41l5erythrocyte membrane protein band 4.1 like 50.239
xirp1xin actin-binding repeat containing 10.231
mybpc3myosin binding protein C, cardiac0.229
smad9MAD homolog 9 (Drosophila)0.228
cdc37cell division cycle 37 homolog (S. cerevisiae)0.228
ncapgnon-SMC condensin I complex, subunit G0.227
actn2actinin, alpha 20.224
chrna1cholinergic receptor, nicotinic, alpha polypeptide 10.222
wu:fl55e11wu:fl55e110.222
yap1Yes-associated protein 10.222
stilTAL1 (SCL) interrupting locus0.221
tnnt3btroponin T3b, skeletal, fast0.221
myogmyogenin0.219
rps3aribosomal protein S3A0.219
si:dkeyp-84f11.5si:dkeyp-84f11.50.218
si:ch211-212m21.5si:ch211-212m21.50.218
ywhabltyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like0.218
rap1bRAS related protein 1b0.216
cdc42cell division cycle 420.216
rpl15ribosomal protein L150.213
gnai2lguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like0.212
rpl13ribosomal protein L130.210
dlddeltaD0.208
hoxa3ahomeo box A3a0.204
sema3aasemaphorin 3aa0.204
hspg2heparan sulfate proteoglycan 20.203
prickle1aprickle-like 1 (Drosophila) a0.203
zbtb4zinc finger and BTB domain containing 40.201
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Tpm3tropomyosin 3, gamma0.852
Arpc1bactin related protein 2/3 complex, subunit 1B0.843
Myh9myosin, heavy chain 9, non-muscle0.840
Efhd2EF-hand domain family, member D20.705
Wdr1WD repeat domain 10.660
Actn4actinin alpha 40.633
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.623
Taglntransgelin0.619
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.606
Acta2smooth muscle alpha-actin0.548
Cttncortactin0.524
Myh7myosin, heavy chain 7, cardiac muscle, beta0.521
Arpc2actin related protein 2/3 complex, subunit 20.501
Arf6ADP-ribosylation factor 60.477
Gnai3guanine nucleotide binding protein (G protein), alpha inhibiting 30.472
Tpm2tropomyosin 2, beta0.468
Pfn1profilin 10.457
Stk10serine/threonine kinase 100.444
Nlgn2neuroligin 20.421
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.407
Sirpasignal-regulatory protein alpha0.407
Ckmcreatine kinase, muscle0.394
Iqgap1IQ motif containing GTPase activating protein 10.393
Cd37CD37 molecule0.387
Mapk3mitogen activated protein kinase 30.381
Lmnalamin A0.380
Flnafilamin A, alpha0.373
Tagln2transgelin 20.372
Anxa2annexin A20.370
Ptbp1polypyrimidine tract binding protein 10.347
Cand1cullin-associated and neddylation-dissociated 10.337
Actn1actinin, alpha 10.334
CnbpCCHC-type zinc finger, nucleic acid binding protein0.332
Mapk1mitogen activated protein kinase 10.330
Dstndestrin0.327
Dlg4discs, large homolog 4 (Drosophila)0.326
Actc1actin, alpha, cardiac muscle 10.325
Mobkl2aMOB1, Mps One Binder kinase activator-like 2A (yeast)0.303
Dlg1discs, large homolog 1 (Drosophila)0.300
Tubb5tubulin, beta 50.300
Vaspvasodilator-stimulated phosphoprotein0.299
Cugbp2CUG triplet repeat, RNA binding protein 20.293
Coro1acoronin, actin binding protein 1A0.281
Csrp1cysteine and glycine-rich protein 10.279
Hckhemopoietic cell kinase0.276
S100a10S100 calcium binding protein A100.275
Uba1ubiquitin-like modifier activating enzyme 10.267
Actbactin, beta0.266
Cryabcrystallin, alpha B0.264
Tmsb10thymosin, beta 100.263
Gng7guanine nucleotide binding protein (G protein), gamma 70.262
Ptprcprotein tyrosine phosphatase, receptor type, C0.261
Gna12guanine nucleotide binding protein (G protein) alpha 120.257
Stip1stress-induced phosphoprotein 10.254
Tpm1tropomyosin 1, alpha0.248
Tgoln1trans-golgi network protein0.246
Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.244
Trim29tripartite motif-containing 290.242
Lcp2lymphocyte cytosolic protein 20.240
Atp2b4ATPase, Ca++ transporting, plasma membrane 40.239
Chrna4cholinergic receptor, nicotinic, alpha 40.236
Exoc5exocyst complex component 50.230
Laptm5lysosomal protein transmembrane 50.229
Mapre1microtubule-associated protein, RP/EB family, member 10.223
Emp1epithelial membrane protein 10.220
Gmfgglia maturation factor, gamma0.219
Arf3ADP-ribosylation factor 30.216
Pex5lperoxisomal biogenesis factor 5-like0.214
Cct2chaperonin containing TCP1, subunit 2 (beta)0.213
Ncf4neutrophil cytosolic factor 40.212
Rhoaras homolog gene family, member A0.211
Dpysl3dihydropyrimidinase-like 30.209
Ccl3chemokine (C-C motif) ligand 30.204
Robo2roundabout homolog 2 (Drosophila)0.204
Rplp0ribosomal protein, large, P00.202
Arpc3actin related protein 2/3 complex, subunit 30.198
Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform0.196
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.193
Cd82Cd82 molecule0.193
Inpp5dinositol polyphosphate-5-phosphatase D0.191
Ptmaprothymosin alpha0.188
LOC685045similar to Protein C6orf1150.187
Npm1nucleophosmin (nucleolar phosphoprotein B23, numatrin)0.185
Notch3Notch homolog 3 (Drosophila)0.184
Ptpn6protein tyrosine phosphatase, non-receptor type 60.183
Eef2eukaryotic translation elongation factor 20.181
Tgfb1transforming growth factor, beta 10.181
Ube2cubiquitin-conjugating enzyme E2C0.177
Desdesmin0.176
Map2microtubule-associated protein 20.176
Map1amicrotubule-associated protein 1A0.175
Ripk3receptor-interacting serine-threonine kinase 30.174
Prkcgprotein kinase C, gamma0.173
Sdc1syndecan 10.168
ArhgdibRho, GDP dissociation inhibitor (GDI) beta0.166
Gja6gap junction protein, alpha 60.163
Vav1vav 1 guanine nucleotide exchange factor0.159
Actn2actinin alpha 20.159
Ifngr1interferon gamma receptor 10.158
Cfpcomplement factor properdin0.158
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
DAM1Dam1p1.000
RVS167Rvs167p0.999
TID3Tid3p0.994
ARP2Arp2p0.994
ASK1Ask1p0.994
CRN1Crn1p0.993
NUF2Nuf2p0.984
BIM1Bim1p0.983
MPS1Mps1p0.981
SPC34Spc34p0.979
SPC24Spc24p0.979
AKL1Akl1p0.971
ACT1Act1p0.968
SPC97Spc97p0.968
RAD23Rad23p0.957
CMD1Cmd1p0.955
CLB3Clb3p0.951
MYO5Myo5p0.949
CDC25Cdc25p0.949
CIN8Cin8p0.944
SPA2Spa2p0.939
END3End3p0.937
BUD6Bud6p0.936
GIN4Gin4p0.925
LAS17Las17p0.923
ARC35Arc35p0.916
SSK2Ssk2p0.915
SPC29Spc29p0.910
ARC15Arc15p0.892
HSL1Hsl1p0.878
KEL1Kel1p0.877
YPK1Ypk1p0.875
SPC110Spc110p0.874
CBF2Cbf2p0.870
PAC10Pac10p0.867
RHO1Rho1p0.866
ARC40Arc40p0.864
RPS8ARps8ap0.861
SPC19Spc19p0.858
DAD4Dad4p0.855
ARP3Arp3p0.854
DUO1Duo1p0.846
DAD2Dad2p0.838
SAC6Sac6p0.835
SLA2Sla2p0.835
CDC24Cdc24p0.825
KAR9Kar9p0.825
ARC18Arc18p0.824
DBF2Dbf2p0.822
BBP1Bbp1p0.820
DYN1Dyn1p0.816
SYP1Syp1p0.814
TSC11Tsc11p0.811
BMH2Bmh2p0.809
BBC1Bbc1p0.805
SRV2Srv2p0.801
MOB1Mob1p0.799
NIP100Nip100p0.798
CDC55Cdc55p0.795
DAD1Dad1p0.792
SPC42Spc42p0.780
SLM2Slm2p0.776
CAP1Cap1p0.773
CDC28Cdc28p0.771
SPC105Spc105p0.765
CDC12Cdc12p0.760
RPT3Rpt3p0.742
SHS1Shs1p0.738
RFC5Rfc5p0.724
ABP1Abp1p0.718
FUN12Fun12p0.708
BEM2Bem2p0.708
NDC1Ndc1p0.706
SGO1Sgo1p0.703
CNM67Cnm67p0.697
GIC2Gic2p0.694
RPL17ARpl17ap0.691
NBP2Nbp2p0.667
SPC98Spc98p0.666
SMI1Smi1p0.663
PEX13Pex13p0.659
ZDS1Zds1p0.659
BEM4Bem4p0.657
TPM1Tpm1p0.652
RPL17BRpl17bp0.647
CDC5Cdc5p0.647
DSN1Dsn1p0.642
CDC20Cdc20p0.639
PHO85Pho85p0.627
AIM3Aim3p0.626
UBA4Uba4p0.625
RPS1ARps1ap0.620
RPL16ARpl16ap0.612
SWE1Swe1p0.610
BIK1Bik1p0.609
EDE1Ede1p0.606
MYO2Myo2p0.604
CLA4Cla4p0.598
RPL4BRpl4bp0.596
HTA2Hta2p0.594