The network for 'regulation of muscle system process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of muscle system process

Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system.

NameDescriptionProbabilityFunc Analog Organism
msp-78Protein MSP-780.747
msp-77Protein MSP-770.458
msp-76Protein MSP-760.252
stn-1Protein STN-10.235
msp-36Protein MSP-360.232
unc-43Protein UNC-430.228
msp-55Protein MSP-550.220
CELE_Y59E9AR.7Protein Y59E9AR.70.181
msp-59Protein MSP-590.177
msp-38Protein MSP-380.163
unc-29Protein UNC-290.158
msp-31Protein MSP-310.134
unc-27Protein UNC-270.128
msp-74Protein MSP-740.128
msp-3Protein MSP-30.121
msp-64Protein MSP-640.115
msp-40Protein MSP-400.114
lev-8Protein LEV-80.108
unc-112Protein UNC-1120.107
msp-53Protein MSP-530.101
T28B4.1Protein T28B4.10.101
unc-25Protein UNC-250.089
pkg-1Protein PKG-10.089
acr-8Protein ACR-80.088
hsp-12.2Protein HSP-12.20.085
msp-50Protein MSP-500.084
T21B6.3Protein T21B6.30.081
msp-19Protein MSP-190.079
C53C9.2Protein C53C9.20.077
twk-18Protein TWK-180.076
msp-152Protein MSP-1520.072
msp-32Protein MSP-320.070
Y45F10A.7Protein Y45F10A.70.070
mab-3Protein MAB-30.070
msp-45Protein MSP-450.065
F35A5.1Protein F35A5.10.064
msp-49Protein MSP-490.054
unc-96Protein UNC-960.053
lev-1Protein LEV-10.051
dys-1Protein DYS-10.050
egl-30Protein EGL-300.050
lgc-34Protein LGC-340.047
unc-15Protein UNC-150.047
unc-45Protein UNC-450.047
msp-65Protein MSP-650.045
msp-10Protein MSP-100.044
Y59H11AM.1Protein Y59H11AM.10.044
acr-16Protein ACR-160.043
insc-1Protein INSC-10.043
F26F12.4Protein F26F12.40.040
F37C4.5Protein F37C4.50.037
tni-4Protein TNI-40.036
msp-33Protein MSP-330.036
ifa-1Protein IFA-10.033
T25F10.6Protein T25F10.60.033
rab-3Protein RAB-30.033
dim-1Protein DIM-10.032
ipp-5Protein IPP-50.032
egl-2Protein EGL-20.031
msp-63Protein MSP-630.031
msp-142Protein MSP-1420.029
F58A6.9Protein F58A6.90.029
ssp-19Protein SSP-190.029
ZK1248.17Protein ZK1248.170.029
osm-9Protein OSM-90.028
F41B4.1Protein F41B4.10.028
F44A2.5Protein F44A2.50.027
mpk-1Protein MPK-10.027
snf-11Protein SNF-110.027
ifg-1Protein IFG-10.026
pat-10Protein PAT-100.025
math-4Protein MATH-40.025
T05D4.3Protein T05D4.30.025
ncx-2Protein NCX-20.024
ncx-1Protein NCX-10.024
osm-5Protein OSM-50.024
egl-8Protein EGL-80.023
egl-36Protein EGL-360.023
sek-1Protein SEK-10.023
gar-3Protein GAR-30.023
pry-1Protein PRY-10.023
cpna-1Protein CPNA-10.022
dmsr-1Protein DMSR-10.022
unc-63Protein UNC-630.022
F39H12.3Protein F39H12.30.022
acy-1Protein ACY-10.022
lec-2Protein LEC-20.021
cln-3.1Protein CLN-3.10.021
ZK856.8Protein ZK856.80.021
cka-2Protein CKA-20.021
jnk-1Protein JNK-10.021
odr-3Protein ODR-30.020
ZK1321.4Protein ZK1321.40.020
unc-54Protein UNC-540.020
vav-1Protein VAV-10.020
zyx-1Protein ZYX-10.020
cpn-3Protein CPN-30.020
F46C8.3Protein F46C8.30.020
pxl-1Protein PXL-10.020
myo-3Protein MYO-30.020
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tnni2a.4troponin I, skeletal, fast 2a.40.111
tnnc1btroponin C type 1b (slow)0.034
mybpc3myosin binding protein C, cardiac0.030
cmlc1cardiac myosin light chain-10.029
vmhcventricular myosin heavy chain0.025
ldb3aLIM-domain binding factor 3a0.023
hspb1heat shock protein, alpha-crystallin-related, 10.020
atp1a1a.2ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide0.019
ldb3bLIM domain binding 3b0.018
smyhc2slow myosin heavy chain 20.018
actn2actinin, alpha 20.017
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.017
tnnt3btroponin T3b, skeletal, fast0.014
atp1b1bATPase, Na+/K+ transporting, beta 1b polypeptide0.014
chrna1cholinergic receptor, nicotinic, alpha polypeptide 10.014
pvalb4parvalbumin 40.013
anxa11aannexin A11a0.013
myl7myosin, light polypeptide 7, regulatory0.013
smyhc1lslow myosin heavy chain 1, like0.012
prkczprotein kinase C, zeta0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Tm2Tropomyosin 20.028
Hsp26Heat shock protein 260.012
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SRFserum response factor (c-fos serum response element-binding transcription factor)1.000
ACTN2actinin, alpha 20.997
KCNB1potassium voltage-gated channel, Shab-related subfamily, member 10.994
TNNI1troponin I type 1 (skeletal, slow)0.992
DLG4discs, large homolog 4 (Drosophila)0.980
MPZL2myelin protein zero-like 20.963
HSPB8heat shock 22kDa protein 80.958
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.941
KCNQ1potassium voltage-gated channel, KQT-like subfamily, member 10.936
TNNC1troponin C type 1 (slow)0.927
KCNE1potassium voltage-gated channel, Isk-related family, member 10.911
DSC2desmocollin 20.908
ATP2B2ATPase, Ca++ transporting, plasma membrane 20.899
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.895
SCN5Asodium channel, voltage-gated, type V, alpha subunit0.892
TNNT2troponin T type 2 (cardiac)0.878
TBX5T-box 50.872
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.851
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta0.850
DSG2desmoglein 20.808
MPZL3myelin protein zero-like 30.798
SMAD1SMAD family member 10.782
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.752
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.732
PKP3plakophilin 30.715
CAV1caveolin 1, caveolae protein, 22kDa0.701
ABCA1ATP-binding cassette, sub-family A (ABC1), member 10.700
ESR2estrogen receptor 2 (ER beta)0.664
LDB3LIM domain binding 30.649
ESR1estrogen receptor 10.641
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.640
OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF0.640
SNTG2syntrophin, gamma 20.611
MAPK12mitogen-activated protein kinase 120.602
MYOD1myogenic differentiation 10.600
RIN3Ras and Rab interactor 30.590
HSPB2heat shock 27kDa protein 20.577
PRKAR2Aprotein kinase, cAMP-dependent, regulatory, type II, alpha0.567
PTPRJprotein tyrosine phosphatase, receptor type, J0.563
LIN7Blin-7 homolog B (C. elegans)0.557
MYLPFmyosin light chain, phosphorylatable, fast skeletal muscle0.549
CRYABcrystallin, alpha B0.515
PKP1plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)0.510
VEGFAvascular endothelial growth factor A0.504
MYOGmyogenin (myogenic factor 4)0.490
MAPK1mitogen-activated protein kinase 10.480
KCNIP2Kv channel interacting protein 20.461
ITGB1BP3integrin beta 1 binding protein 30.453
FHL2four and a half LIM domains 20.440
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.438
DTNAdystrobrevin, alpha0.427
HSPB7heat shock 27kDa protein family, member 7 (cardiovascular)0.423
HDAC6histone deacetylase 60.414
NCOA1nuclear receptor coactivator 10.408
BMPR1Bbone morphogenetic protein receptor, type IB0.403
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.379
MYOZ1myozenin 10.379
CALCAcalcitonin-related polypeptide alpha0.378
MYH7myosin, heavy chain 7, cardiac muscle, beta0.372
KRT14keratin 140.359
SMURF2SMAD specific E3 ubiquitin protein ligase 20.341
TRPC3transient receptor potential cation channel, subfamily C, member 30.336
ATP2A1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.327
CYR61cysteine-rich, angiogenic inducer, 610.326
SPTBspectrin, beta, erythrocytic0.326
PSEN1presenilin 10.320
SGCAsarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)0.310
COX6A2cytochrome c oxidase subunit VIa polypeptide 20.304
CSRP3cysteine and glycine-rich protein 3 (cardiac LIM protein)0.293
CKMcreatine kinase, muscle0.293
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.287
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.282
PKD1polycystic kidney disease 1 (autosomal dominant)0.279
MYL2myosin, light chain 2, regulatory, cardiac, slow0.274
KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)0.270
PGFplacental growth factor0.258
ABCC8ATP-binding cassette, sub-family C (CFTR/MRP), member 80.254
TNNT3troponin T type 3 (skeletal, fast)0.245
EIF3Feukaryotic translation initiation factor 3, subunit F0.242
TNNC2troponin C type 2 (fast)0.236
ARRDC3arrestin domain containing 30.235
ITPR2inositol 1,4,5-trisphosphate receptor, type 20.235
YAP1Yes-associated protein 10.231
C3orf15chromosome 3 open reading frame 150.228
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.219
CAV2caveolin 20.217
ACTA1actin, alpha 1, skeletal muscle0.203
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.202
SNTA1syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)0.199
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.196
PTPRBprotein tyrosine phosphatase, receptor type, B0.193
FGFR1fibroblast growth factor receptor 10.192
CYLDcylindromatosis (turban tumor syndrome)0.192
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ldb3LIM domain binding 30.999
Nos3nitric oxide synthase 3, endothelial cell0.998
Ryr2ryanodine receptor 2, cardiac0.997
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.996
Nos1nitric oxide synthase 1, neuronal0.991
Smad3MAD homolog 3 (Drosophila)0.987
Actn2actinin alpha 20.981
Scn5asodium channel, voltage-gated, type V, alpha0.980
Mef2dmyocyte enhancer factor 2D0.980
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.979
Kcnk3potassium channel, subfamily K, member 30.962
Tnni2troponin I, skeletal, fast 20.948
Pthlhparathyroid hormone-like peptide0.907
Hrchistidine rich calcium binding protein0.879
Dmddystrophin, muscular dystrophy0.847
Gja5gap junction protein, alpha 50.831
Nppanatriuretic peptide type A0.831
Cacna1scalcium channel, voltage-dependent, L type, alpha 1S subunit0.824
Smad4MAD homolog 4 (Drosophila)0.814
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.804
Mef2cmyocyte enhancer factor 2C0.798
Pdgfbplatelet derived growth factor, B polypeptide0.792
Casq2calsequestrin 20.773
Epas1endothelial PAS domain protein 10.773
Tbx3T-box 30.760
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.748
Pygmmuscle glycogen phosphorylase0.734
Kcnj5potassium inwardly-rectifying channel, subfamily J, member 50.734
Myl3myosin, light polypeptide 30.727
Chrm3cholinergic receptor, muscarinic 3, cardiac0.714
Hand2heart and neural crest derivatives expressed transcript 20.696
Myom2myomesin 20.694
Actc1actin, alpha, cardiac muscle 10.659
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.656
Cckbrcholecystokinin B receptor0.654
Myod1myogenic differentiation 10.645
Drd2dopamine receptor D20.638
Kcna2potassium voltage-gated channel, shaker-related subfamily, member 20.631
Gucy1b3guanylate cyclase 1, soluble, beta 30.629
Ank1ankyrin 1, erythroid0.627
Sgcasarcoglycan, alpha (dystrophin-associated glycoprotein)0.624
Tnnt2troponin T2, cardiac0.618
Ptprbprotein tyrosine phosphatase, receptor type, B0.613
Mybpc3myosin binding protein C, cardiac0.602
Gja1gap junction protein, alpha 10.593
Dlg4discs, large homolog 4 (Drosophila)0.593
Myh7myosin, heavy polypeptide 7, cardiac muscle, beta0.591
Tbx5T-box 50.590
Emid2EMI domain containing 20.588
Slc12a1solute carrier family 12, member 10.585
Gata6GATA binding protein 60.583
Cacng1calcium channel, voltage-dependent, gamma subunit 10.578
Adrb1adrenergic receptor, beta 10.574
Smyd1SET and MYND domain containing 10.571
Ptgs2prostaglandin-endoperoxide synthase 20.562
Nppbnatriuretic peptide type B0.555
Gdf5growth differentiation factor 50.544
Ckmt2creatine kinase, mitochondrial 20.543
Gsk3bglycogen synthase kinase 3 beta0.539
Sgcgsarcoglycan, gamma (dystrophin-associated glycoprotein)0.534
Ryr1ryanodine receptor 1, skeletal muscle0.529
Tnnc2troponin C2, fast0.526
Myh11myosin, heavy polypeptide 11, smooth muscle0.524
Htra3HtrA serine peptidase 30.522
Tnnt3troponin T3, skeletal, fast0.511
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.510
Pcdh12protocadherin 120.504
Axin1axin 10.500
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.490
Lhx6LIM homeobox protein 60.488
Hcn4hyperpolarization-activated, cyclic nucleotide-gated K+ 40.475
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.474
Srpk3serine/arginine-rich protein specific kinase 30.470
Sstr1somatostatin receptor 10.465
Xirp1xin actin-binding repeat containing 10.462
Nedd4lneural precursor cell expressed, developmentally down-regulated gene 4-like0.462
Prkceprotein kinase C, epsilon0.440
Hspb7heat shock protein family, member 7 (cardiovascular)0.440
Pax7paired box gene 70.438
Gjb6gap junction protein, beta 60.431
Mybphmyosin binding protein H0.430
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.427
Agtr1aangiotensin II receptor, type 1a0.407
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.405
Atp1b2ATPase, Na+/K+ transporting, beta 2 polypeptide0.401
Galr2galanin receptor 20.396
Cd247CD247 antigen0.396
Kcnj6potassium inwardly-rectifying channel, subfamily J, member 60.390
P2rx6purinergic receptor P2X, ligand-gated ion channel, 60.379
Mpzmyelin protein zero0.376
Fgf7fibroblast growth factor 70.369
Myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.367
Scn10asodium channel, voltage-gated, type X, alpha0.363
Cox6a2cytochrome c oxidase, subunit VI a, polypeptide 20.363
Myom1myomesin 10.362
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.359
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Casq2calsequestrin 2 (cardiac muscle)0.529
Myl1myosin, light chain 10.438
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.300
Crhbpcorticotropin releasing hormone binding protein0.280
Cd4Cd4 molecule0.270
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.259
Doc2bdouble C2-like domains, beta0.253
Cd37CD37 molecule0.251
Cav3caveolin 30.242
Ckmcreatine kinase, muscle0.218
Ldb3LIM domain binding 30.213
Testintestin gene0.209
Fgf16fibroblast growth factor 160.207
Egr4early growth response 40.199
Gzmkgranzyme K0.193
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.193
P2rx2purinergic receptor P2X, ligand-gated ion channel, 20.184
Hspb1heat shock protein 10.184
Gfi1growth factor independent 1 transcription repressor0.172
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.164
Chrna1cholinergic receptor, nicotinic, alpha 1 (muscle)0.162
Col10a1collagen, type X, alpha 10.153
Trhr2thyrotropin releasing hormone receptor 20.153
Ednraendothelin receptor type A0.153
Tnnc2troponin C type 2 (fast)0.153
Hsd3b5hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 50.152
Csrp3cysteine and glycine-rich protein 30.151
Plb1phospholipase B10.146
Abcc8ATP-binding cassette, subfamily C (CFTR/MRP), member 80.144
Adra2cadrenergic, alpha-2C-, receptor0.142
Fgf10fibroblast growth factor 100.137
Pfkfb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 20.136
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.135
Chrm2cholinergic receptor, muscarinic 20.135
Rims1regulating synaptic membrane exocytosis 10.134
Fgf7fibroblast growth factor 70.124
Olr226olfactory receptor 2260.124
Ampd1adenosine monophosphate deaminase 1 (isoform M)0.122
Actc1actin, alpha, cardiac muscle 10.122
Apobec2apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 20.120
Inpp5dinositol polyphosphate-5-phosphatase D0.120
Myh6myosin, heavy chain 6, cardiac muscle, alpha0.120
Gfra2GDNF family receptor alpha 20.118
Hspa8heat shock protein 80.116
Scn5asodium channel, voltage-gated, type V, alpha subunit0.109
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.107
Cav1caveolin 1, caveolae protein0.107
Dlx5distal-less homeobox 50.106
Ptgfrprostaglandin F receptor0.106
Mamdc4MAM domain containing 40.104
Itgamintegrin, alpha M0.103
Glp1rglucagon-like peptide 1 receptor0.101
Muskmuscle, skeletal, receptor tyrosine kinase0.100
Oprk1opioid receptor, kappa 10.097
Kcnk3potassium channel, subfamily K, member 30.097
Mchr1melanin-concentrating hormone receptor 10.097
Procprotein C0.095
Figfc-fos induced growth factor0.095
Sirpasignal-regulatory protein alpha0.095
Myh3myosin, heavy chain 3, skeletal muscle, embryonic0.095
Gucy1b3guanylate cyclase 1, soluble, beta 30.094
Hspb2heat shock protein beta 20.093
Prg2proteoglycan 2, bone marrow0.092
Aqp2aquaporin 2 (collecting duct)0.091
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.091
Tacr2tachykinin receptor 20.090
RGD1559748similar to Palate lung and nasal carcinoma-like protein precursor (Tongue plunc-like protein)0.089
Prkcdprotein kinase C, delta0.088
Capn9calpain 90.088
Ppyr1pancreatic polypeptide receptor 10.086
Cx3cr1chemokine (C-X3-C motif) receptor 10.086
Grik3glutamate receptor, ionotropic, kainate 30.086
Cryabcrystallin, alpha B0.086
Vipvasoactive intestinal peptide0.085
Slc18a3solute carrier family 18 (vesicular acetylcholine), member 30.085
Cfpcomplement factor properdin0.084
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.084
Slc22a7solute carrier family 22 (organic anion transporter), member 70.084
Clec11aC-type lectin domain family 11, member a0.083
Pla2g5phospholipase A2, group V0.083
Actn2actinin alpha 20.083
Kcnj4potassium inwardly-rectifying channel, subfamily J, member 40.082
Pnliprp2pancreatic lipase-related protein 20.082
Atp2a3ATPase, Ca++ transporting, ubiquitous0.081
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.081
Mmp2matrix metallopeptidase 20.081
MrgprfMAS-related GPR, member F0.081
Nlgn3neuroligin 30.080
Hcrtr2hypocretin (orexin) receptor 20.079
Ank1ankyrin 1, erythrocytic0.079
Kcnmb1potassium large conductance calcium-activated channel, subfamily M, beta member 10.078
Tff1trefoil factor 10.078
Slc6a11solute carrier family 6 (neurotransmitter transporter, GABA), member 110.078
Lst1leukocyte specific transcript 10.078
Myoz1myozenin 10.077
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism