The network for 'cellular response to organic substance' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to organic substance

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.

NameDescriptionProbabilityFunc Analog Organism
unc-9Protein UNC-90.803
nhr-67Protein NHR-670.770
vab-3Protein VAB-30.691
F13H6.1Protein F13H6.10.666
hsp-16.1Protein HSP-16.10.611
abu-11Protein ABU-110.604
pha-4Protein PHA-40.584
hsp-3Protein HSP-30.561
abu-6Protein ABU-60.533
mat-3Protein MAT-30.520
daf-11Protein DAF-110.481
hsp-16.2Protein HSP-16.20.469
tag-320Protein TAG-3200.464
egl-18Protein EGL-180.463
hsp-4Protein HSP-40.444
Y47D3B.6Protein Y47D3B.60.428
hsp-16.41Protein HSP-16.410.417
unc-104Protein UNC-1040.410
dlk-1Protein DLK-10.410
bar-1Protein BAR-10.407
abu-15Protein ABU-150.398
nhr-45Protein NHR-450.391
sas-5Protein SAS-50.375
ceh-20Protein CEH-200.359
egg-6Protein EGG-60.353
vit-2Protein VIT-20.353
egl-8Protein EGL-80.347
hsp-1Protein HSP-10.345
daf-1Protein DAF-10.334
pkg-1Protein PKG-10.326
F44E5.4Protein F44E5.40.321
apl-1Protein APL-10.314
abu-1Protein ABU-10.310
peb-1Protein PEB-10.300
tbb-2Protein TBB-20.298
acs-4Protein ACS-40.290
pry-1Protein PRY-10.280
apc-2Protein APC-20.273
let-60Protein LET-600.270
hlh-2Protein HLH-20.263
ifg-1Protein IFG-10.260
pod-2Protein POD-20.254
nhr-6Protein NHR-60.247
soc-2Protein SOC-20.246
plc-1Protein PLC-10.244
faah-1Protein FAAH-10.241
daf-14Protein DAF-140.240
abu-14Protein ABU-140.240
daf-12Protein DAF-120.236
glp-1Protein GLP-10.229
unc-70Protein UNC-700.225
ccch-1Protein CCCH-10.223
cam-1Protein CAM-10.221
trap-3Protein TRAP-30.219
lin-1Protein LIN-10.219
hsp-70Protein HSP-700.216
CELE_C18C4.5Protein C18C4.50.213
hsp-16.48Protein HSP-16.480.213
cpr-4Protein CPR-40.210
sma-3Protein SMA-30.210
unc-52Protein UNC-520.209
smp-1Protein SMP-10.206
ztf-22Protein ZTF-220.205
imp-2Protein IMP-20.205
npl-4.2Protein NPL-4.20.205
ptr-14Protein PTR-140.202
nra-4Protein NRA-40.199
CELE_Y57A10A.13Protein Y57A10A.130.199
sgt-1Protein SGT-10.195
ace-3Protein ACE-30.192
calu-1Protein CALU-10.188
unc-83Protein UNC-830.188
sup-17Protein SUP-170.186
emb-9Protein EMB-90.186
imb-2Protein IMB-20.185
K03E6.7Protein K03E6.70.185
fln-2Protein FLN-20.185
csn-4Protein CSN-40.184
lpd-6Protein LPD-60.175
pqn-54Protein PQN-540.175
osm-6Protein OSM-60.174
lin-25Protein LIN-250.172
F40F4.7Protein F40F4.70.172
par-5Protein PAR-50.171
pqn-59Protein PQN-590.166
haly-1Protein HALY-10.166
elt-6Protein ELT-60.166
npp-1Protein NPP-10.161
pde-4Protein PDE-40.161
lmn-1Protein LMN-10.161
fkh-2Protein FKH-20.160
cat-1Protein CAT-10.158
pmt-1Protein PMT-10.158
pmk-1Protein PMK-10.152
immt-1Protein IMMT-10.152
atg-11Protein ATG-110.152
C27A12.7Protein C27A12.70.151
sek-1Protein SEK-10.149
spp-10Protein SPP-100.148
ser-3Protein SER-30.147
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
fgf8afibroblast growth factor 8 a0.943
bmp2bbone morphogenetic protein 2b0.928
shhasonic hedgehog a0.894
fgf3fibroblast growth factor 30.859
apoebapolipoprotein Eb0.728
oepone-eyed pinhead0.727
sox9aSRY-box containing gene 9a0.710
pax6apaired box gene 6a0.694
trpv6transient receptor potential cation channel, subfamily V, member 60.684
lef1lymphocyte enhancer binding factor 10.679
dlcdeltaC0.671
chdchordin0.667
efnb2aephrin B2a0.650
pax8paired box gene 80.644
tfap2atranscription factor AP-2 alpha0.631
flhfloating head0.616
spry4sprouty (Drosophila) homolog 40.600
otpaorthopedia homolog a0.597
notch1anotch homolog 1a0.573
dlx5adistal-less homeobox gene 5a0.565
tal1T-cell acute lymphocytic leukemia 10.538
bmp4bone morphogenetic protein 40.533
foxa3forkhead box A30.530
snai1asnail homolog 1a (Drosophila)0.515
ptch2patched 20.495
sox9bSRY-box containing gene 9b0.493
ndr2nodal-related 20.492
igf1rainsulin-like growth factor 1a receptor0.489
wnt10awingless-type MMTV integration site family, member 10a0.480
tbx18T-box 180.471
osr1odd-skipped related 1 (Drosophila)0.460
plcg1phospholipase C, gamma 10.441
nog3noggin 30.435
cmybtranscription factor cmyb0.407
hspa5heat shock protein 50.405
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.379
fn1fibronectin 10.371
vdravitamin D receptor a0.366
jag2jagged 20.364
tgfb1atransforming growth factor, beta 1a0.354
nanos3nanos homolog 30.352
nadl1.1neural adhesion molecule L1.10.351
cdh23cadherin-like 230.351
pcnaproliferating cell nuclear antigen0.349
hspd1heat shock 60kD protein 1 (chaperonin)0.348
sparcsecreted acidic cysteine rich glycoprotein0.343
manfmesencephalic astrocyte-derived neurotrophic factor0.340
lin28alin-28 homolog A (C. elegans)0.338
gro1groucho 10.332
fzd5frizzled homolog 50.323
fabp11afatty acid binding protein 11a0.321
si:dkey-27i16.2si:dkey-27i16.20.310
nkx2.2aNK2 transcription factor related 2a0.307
wnt2wingless-type MMTV integration site family member 20.300
tbx1T-box 10.295
gdf6agrowth differentiation factor 6a0.294
fgf10afibroblast growth factor 10a0.292
gli2aGLI-Kruppel family member GLI2a0.291
esr1estrogen receptor 10.290
neo1neogenin 10.289
fgf4fibroblast growth factor 40.284
cdx4caudal type homeo box transcription factor 40.283
pycardPYD and CARD domain containing0.281
wt1awilms tumor 1a0.280
pitx3paired-like homeodomain transcription factor 30.278
jag1ajagged 1a0.277
ef1aelongation factor 1-alpha0.277
cdh2cadherin 2, neuronal0.272
igf1insulin-like growth factor 10.269
dladeltaA0.265
ptpraprotein tyrosine phosphatase, receptor type, A0.264
rag1recombination activating gene 10.254
wu:fv91b12wu:fv91b120.246
kif5bbkinesin family member 5B, b0.245
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.245
sema3aasemaphorin 3aa0.236
notch3notch homolog 30.234
etv2ets variant gene 20.233
fras1Fraser syndrome 10.232
her12hairy-related 120.229
vasavasa homolog0.228
cav1caveolin 10.228
metmet proto-oncogene (hepatocyte growth factor receptor)0.227
sulf1sulfatase 10.221
smad7MAD, mothers against decapentaplegic homolog 7 (Drosophila)0.219
vcanbversican b0.218
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.215
cyp26a1cytochrome P450, subfamily XXVIA, polypeptide 10.214
vcanaversican a0.211
sec61al1Sec61 alpha like 10.210
hyou1hypoxia up-regulated 10.210
mmp2matrix metalloproteinase 20.209
lmo4aLIM domain only 4a0.209
pcdh18bprotocadherin 18b0.205
fbn2bfibrillin 2b0.203
btg2B-cell translocation gene 20.203
pou5f1POU domain, class 5, transcription factor 10.200
wnt8bwingless-type MMTV integration site family, member 8b0.199
rarabretinoic acid receptor, alpha b0.198
bmperBMP binding endothelial regulator0.197
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Stat92ESignal-transducer and activator of transcription protein at 92E0.954
Rac1CG2248 gene product from transcript CG2248-RA0.949
MerMerlin0.948
smt3CG4494 gene product from transcript CG4494-RA0.888
putpunt0.882
EcREcdysone receptor0.864
EgfrEpidermal growth factor receptor0.856
Ras85DRas oncogene at 85D0.829
cicubitus interruptus0.784
tkvthickveins0.772
RelRelish0.761
Pi3K92ECG4141 gene product from transcript CG4141-RB0.738
sinaseven in absentia0.731
nejnejire0.711
Fmr1CG6203 gene product from transcript CG6203-RC0.692
dacdachshund0.683
Lis-1Lissencephaly-10.670
ShcSHC-adaptor protein0.666
CtBPC-terminal Binding Protein0.627
p53CG33336 gene product from transcript CG33336-RB0.613
hephemipterous0.552
S6kRPS6-p70-protein kinase0.551
Top2Topoisomerase 20.550
Nrx-IVNeurexin IV0.524
bowlbrother of odd with entrails limited0.510
SfmbtScm-related gene containing four mbt domains0.509
MoeMoesin0.478
fkhfork head0.473
lwrlesswright0.464
ash2absent, small, or homeotic discs 20.462
apapterous0.455
Cdk4Cyclin-dependent kinase 40.455
AtpalphaNa pump alpha subunit0.452
rapretina aberrant in pattern0.439
trxtrithorax0.423
HopHsp70/Hsp90 organizing protein homolog0.422
Fas2Fasciclin 20.411
CycJCyclin J0.407
ftz-f1ftz transcription factor 10.392
btlbreathless0.387
SmoxSmad on X0.384
phlpole hole0.378
uspultraspiracle0.371
par-1CG8201 gene product from transcript CG8201-RA0.366
gcmglial cells missing0.366
wtswarts0.360
InRInsulin-like receptor0.353
MedMedea0.351
DadDaughters against dpp0.350
Dcr-1Dicer-10.344
rictorrapamycin-insensitive companion of Tor0.344
Gyc76CGuanylyl cyclase at 76C0.335
LamCLamin C0.332
p38bCG7393 gene product from transcript CG7393-RA0.327
Su(H)Suppressor of Hairless0.321
dsxdoublesex0.320
shnschnurri0.320
htshu li tai shao0.320
lokloki0.319
btzbarentsz0.317
Cdc42CG12530 gene product from transcript CG12530-RA0.311
NNotch0.307
foxoforkhead box, sub-group O0.303
dppdecapentaplegic0.293
G-oalpha47AG protein oalpha 47A0.289
mysmyospheroid0.285
mormoira0.282
fz2frizzled 20.278
emcextra macrochaetae0.277
rutrutabaga0.273
UbqnUbiquilin0.273
eveeven skipped0.270
wunwunen0.269
aPKCatypical protein kinase C0.264
toutoutatis0.260
hthhomothorax0.260
maskmultiple ankyrin repeats single KH domain0.257
dmdiminutive0.253
chicoCG5686 gene product from transcript CG5686-RB0.250
awdabnormal wing discs0.249
Jarid2CG3654 gene product from transcript CG3654-RD0.242
Kr-h1Kruppel homolog 10.242
ptcpatched0.240
knknot0.235
eyeyeless0.233
keykenny0.232
CdsACDP diglyceride synthetase0.231
botvbrother of tout-velu0.230
HsfHeat shock factor0.230
sflsulfateless0.228
Vap-33-1CG5014 gene product from transcript CG5014-RB0.226
neurneuralized0.224
spzspatzle0.223
imdimmune deficiency0.220
fufused0.219
ushu-shaped0.213
crmcramped0.210
dallydivision abnormally delayed0.208
CapsCalcium activated protein for secretion0.206
Cg25CCollagen type IV0.205
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
FAR1Far1p0.991
STE11Ste11p0.984
STE5Ste5p0.964
STE4Ste4p0.945
BEM1Bem1p0.939
SST2Sst2p0.899
AGA1Aga1p0.889
CDC24Cdc24p0.848
FUS3Fus3p0.841
STE20Ste20p0.802
NBP2Nbp2p0.781
STE2Ste2p0.777
PTC1Ptc1p0.657
SLT2Slt2p0.655
STE7Ste7p0.651
GPA1Gpa1p0.639
RAS2Ras2p0.637
TOR1Tor1p0.629
CRZ1Crz1p0.628
CDC55Cdc55p0.621
HOG1Hog1p0.614
AGA2Aga2p0.614
PPH21Pph21p0.599
STE18Ste18p0.570
RTG3Rtg3p0.569
MFA1Mfa1p0.541
FUS1Fus1p0.523
YSC84Ysc84p0.490
SSK2Ssk2p0.483
HSP104Hsp104p0.481
KSS1Kss1p0.458
CLA4Cla4p0.455
STE50Ste50p0.454
FIG4Fig4p0.447
FIG2Fig2p0.429
PBS2Pbs2p0.429
RHO1Rho1p0.425
DBF2Dbf2p0.422
SSK1Ssk1p0.419
GLN3Gln3p0.415
ARF1Arf1p0.389
MKS1Mks1p0.387
FAR10Far10p0.381
CLB3Clb3p0.378
CHD1Chd1p0.378
PDE2Pde2p0.371
RLM1Rlm1p0.369
SIC1Sic1p0.362
TRA1Tra1p0.350
DIG1Dig1p0.350
CLN3Cln3p0.346
MSN2Msn2p0.341
SGV1Sgv1p0.338
RRI1Rri1p0.336
FAR11Far11p0.335
KDX1Kdx1p0.310
FUS2Fus2p0.308
MSN5Msn5p0.305
SWI6Swi6p0.301
GFA1Gfa1p0.300
PPZ1Ppz1p0.299
ROM2Rom2p0.296
AQY2Aqy2p0.293
RTF1Rtf1p0.292
AQR1Aqr1p0.283
SSE2Sse2p0.279
CDC48Cdc48p0.277
KRE1Kre1p0.276
SHO1Sho1p0.276
NOG1Nog1p0.274
SAC7Sac7p0.273
RPN4Rpn4p0.270
STE3Ste3p0.268
CGI121Cgi121p0.265
MPH1Mph1p0.258
MKK1Mkk1p0.254
UBP15Ubp15p0.252
RIM101Rim101p0.252
CYC8Cyc8p0.251
ASG1Asg1p0.251
TCP1Tcp1p0.246
BMH1Bmh1p0.243
HRD1Hrd1p0.243
YJR084Whypothetical protein0.241
FPK1Fpk1p0.239
PRM1Prm1p0.239
CDC28Cdc28p0.238
YPT1Ypt1p0.235
HSP60Hsp60p0.235
CAK1Cak1p0.234
SLG1Slg1p0.229
PHO80Pho80p0.228
BNI1Bni1p0.227
YAK1Yak1p0.224
BAR1Bar1p0.221
PMT2Pmt2p0.221
SGT2Sgt2p0.219
RRI2Rri2p0.219
KSP1Ksp1p0.219
HSP82Hsp82p0.214