The network for 'organ morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

NameDescriptionProbabilityFunc Analog Organism
pha-4Protein PHA-40.928
unc-73Protein UNC-730.919
hlh-1Protein HLH-10.915
egl-18Protein EGL-180.886
epi-1Protein EPI-10.780
sem-5Protein SEM-50.745
atn-1Protein ATN-10.736
che-13Protein CHE-130.705
egl-46Protein EGL-460.574
egl-15Protein EGL-150.564
unc-62Protein UNC-620.552
egl-5Protein EGL-50.540
wrm-1Protein WRM-10.462
fkh-2Protein FKH-20.460
unc-52Protein UNC-520.453
vab-3Protein VAB-30.450
hlh-2Protein HLH-20.436
hbl-1Protein HBL-10.425
lin-12Protein LIN-120.422
ten-1Protein TEN-10.422
ifb-2Protein IFB-20.418
lin-17Protein LIN-170.394
egl-44Protein EGL-440.378
nhr-67Protein NHR-670.362
pry-1Protein PRY-10.359
ajm-1Protein AJM-10.354
irx-1Protein IRX-10.349
sel-12Protein SEL-120.344
T28F4.1Protein T28F4.10.341
osm-5Protein OSM-50.341
rig-6Protein RIG-60.339
egl-27Protein EGL-270.338
bbs-1Protein BBS-10.330
elt-6Protein ELT-60.328
H43E16.1Protein H43E16.10.313
bar-1Protein BAR-10.299
eya-1Protein EYA-10.293
myo-3Protein MYO-30.288
ina-1Protein INA-10.287
plc-1Protein PLC-10.283
eat-6Protein EAT-60.282
sax-7Protein SAX-70.273
clh-5Protein CLH-50.264
ain-1Protein AIN-10.259
ifd-1Protein IFD-10.252
lam-2Protein LAM-20.248
lag-1Protein LAG-10.246
dim-1Protein DIM-10.245
trim-9Protein TRIM-90.239
inx-5Protein INX-50.235
apl-1Protein APL-10.229
pac-1Protein PAC-10.227
mig-6Protein MIG-60.226
nhr-34Protein NHR-340.226
aph-2Protein APH-20.223
cam-1Protein CAM-10.220
goa-1Protein GOA-10.218
unc-98Protein UNC-980.218
lin-29Protein LIN-290.215
vbh-1Protein VBH-10.215
mig-5Protein MIG-50.205
unc-42Protein UNC-420.203
mab-5Protein MAB-50.203
spc-1Protein SPC-10.191
emb-9Protein EMB-90.187
nfi-1Protein NFI-10.186
hmg-1.2Protein HMG-1.20.184
aspm-1Protein ASPM-10.182
sma-6Protein SMA-60.182
attf-2Protein ATTF-20.180
dre-1Protein DRE-10.180
unc-130Protein UNC-1300.177
T21B6.3Protein T21B6.30.177
gly-12Protein GLY-120.175
sel-10Protein SEL-100.171
cwn-1Protein CWN-10.171
fasn-1Protein FASN-10.164
unc-37Protein UNC-370.163
abu-15Protein ABU-150.158
imb-2Protein IMB-20.158
T12D8.9Protein T12D8.90.158
npp-1Protein NPP-10.157
gon-4Protein GON-40.157
tra-1Protein TRA-10.155
CELE_F54D5.5Protein F54D5.50.154
hrpf-2Protein HRPF-20.151
nhr-25Protein NHR-250.151
che-2Protein CHE-20.149
ida-1Protein IDA-10.147
tax-6Protein TAX-60.146
B0336.3Protein B0336.30.145
C53C9.2Protein C53C9.20.143
gei-18Protein GEI-180.143
pup-2Protein PUP-20.142
T20F5.6Protein T20F5.60.141
dnc-2Protein DNC-20.141
lin-14Protein LIN-140.140
nrde-3Protein NRDE-30.140
unc-6Protein UNC-60.139
emb-5Protein EMB-50.138
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor1.000
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)1.000
MYCv-myc myelocytomatosis viral oncogene homolog (avian)1.000
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide1.000
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)1.000
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)1.000
ESR1estrogen receptor 11.000
TP53tumor protein p531.000
YAP1Yes-associated protein 10.999
FLNAfilamin A, alpha0.999
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.999
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.999
FN1fibronectin 10.998
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.998
SP1Sp1 transcription factor0.997
CDK2cyclin-dependent kinase 20.997
CREBBPCREB binding protein0.997
NCOR1nuclear receptor corepressor 10.996
SIN3ASIN3 homolog A, transcription regulator (yeast)0.994
FGFR2fibroblast growth factor receptor 20.994
SMAD2SMAD family member 20.994
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.993
NR4A1nuclear receptor subfamily 4, group A, member 10.991
HDAC1histone deacetylase 10.990
MYOD1myogenic differentiation 10.987
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.986
CAV1caveolin 1, caveolae protein, 22kDa0.986
RUNX1runt-related transcription factor 10.984
TAL1T-cell acute lymphocytic leukemia 10.979
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.976
PTPN1protein tyrosine phosphatase, non-receptor type 10.976
MYH9myosin, heavy chain 9, non-muscle0.975
THBS1thrombospondin 10.972
CTGFconnective tissue growth factor0.972
NOTCH1notch 10.971
PDX1pancreatic and duodenal homeobox 10.966
JAG1jagged 10.966
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.964
HDAC2histone deacetylase 20.962
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.962
COL1A1collagen, type I, alpha 10.957
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.955
TIMP3TIMP metallopeptidase inhibitor 30.953
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.952
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.949
MDM2Mdm2 p53 binding protein homolog (mouse)0.946
MMP14matrix metallopeptidase 14 (membrane-inserted)0.943
YY1YY1 transcription factor0.942
TP63tumor protein p630.941
SMAD7SMAD family member 70.940
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.935
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.935
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.933
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.930
RB1retinoblastoma 10.925
FGF1fibroblast growth factor 1 (acidic)0.924
CSNK2A1casein kinase 2, alpha 1 polypeptide0.918
TCF4transcription factor 40.917
SMAD4SMAD family member 40.915
DVL3dishevelled, dsh homolog 3 (Drosophila)0.913
CDC37cell division cycle 37 homolog (S. cerevisiae)0.909
ARandrogen receptor0.908
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.905
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.901
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.897
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.894
FGFR1fibroblast growth factor receptor 10.893
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.891
GATA4GATA binding protein 40.891
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.889
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.884
HOXB5homeobox B50.883
POU3F2POU class 3 homeobox 20.882
CDK6cyclin-dependent kinase 60.881
RBBP4retinoblastoma binding protein 40.880
VEGFAvascular endothelial growth factor A0.876
KLK10kallikrein-related peptidase 100.870
EPAS1endothelial PAS domain protein 10.868
NOTCH3notch 30.868
GRB7growth factor receptor-bound protein 70.868
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.867
PPARAperoxisome proliferator-activated receptor alpha0.864
CCND1cyclin D10.862
COL1A2collagen, type I, alpha 20.851
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.848
NRP1neuropilin 10.848
TP73tumor protein p730.847
FHL2four and a half LIM domains 20.847
FOXA2forkhead box A20.841
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.840
PAX7paired box 70.837
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.832
CDX2caudal type homeobox 20.831
SCHIP1schwannomin interacting protein 10.829
BCORBCL6 corepressor0.828
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.828
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.827
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.825
CASKcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.824
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Hoxb7homeo box B70.533
Ankrd1ankyrin repeat domain 1 (cardiac muscle)0.507
Col3a1collagen, type III, alpha 10.386
Ednrbendothelin receptor type B0.374
Actc1actin, alpha, cardiac muscle 10.363
Fgfr2fibroblast growth factor receptor 20.356
Col1a1collagen, type I, alpha 10.314
MrgprfMAS-related GPR, member F0.298
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.285
Sirpasignal-regulatory protein alpha0.283
Itpr2inositol 1,4,5-triphosphate receptor, type 20.280
Igfbp5insulin-like growth factor binding protein 50.279
Stat5bsignal transducer and activator of transcription 5B0.274
Foxd3forkhead box D30.273
Klk1lkallikrein 1-like peptidase0.269
Crisp1cysteine-rich secretory protein 10.257
Hoxc4homeo box C40.253
Myo1emyosin IE0.253
Col12a1collagen, type XII, alpha 10.246
Prrx1paired related homeobox 10.245
Dbhdopamine beta-hydroxylase (dopamine beta-monooxygenase)0.237
Bmp6bone morphogenetic protein 60.233
Grk1G protein-coupled receptor kinase 10.231
Tacr1tachykinin receptor 10.229
Sod3superoxide dismutase 3, extracellular0.222
Mybpc1myosin binding protein C, slow type0.221
Gna12guanine nucleotide binding protein (G protein) alpha 120.213
Ireb2iron responsive element binding protein 20.212
Pla1aphospholipase A1 member A0.209
Atp2b3ATPase, Ca++ transporting, plasma membrane 30.205
Krt5keratin 50.195
Tnni3troponin I type 3 (cardiac)0.194
Gata3GATA binding protein 30.194
Amelxamelogenin X chromosome0.193
Efna5ephrin A50.190
Fbln5fibulin 50.188
Myh3myosin, heavy chain 3, skeletal muscle, embryonic0.187
Fn1fibronectin 10.180
Klf13Kruppel-like factor 130.175
Tgfbr2transforming growth factor, beta receptor II0.175
Trpv1transient receptor potential cation channel, subfamily V, member 10.170
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.167
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.165
Shox2short stature homeobox 20.164
Smad7SMAD family member 70.163
Robo1roundabout homolog 1 (Drosophila)0.160
Dchs1dachsous 1 (Drosophila)0.159
Opn1swopsin 1 (cone pigments), short-wave-sensitive0.158
Leprleptin receptor0.156
Krt14keratin 140.153
Col5a2collagen, type V, alpha 20.153
Reg3aregenerating islet-derived 3 alpha0.152
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.152
Sorbs1sorbin and SH3 domain containing 10.152
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.152
Rararetinoic acid receptor, alpha0.151
Col1a2collagen, type I, alpha 20.149
Ptprcprotein tyrosine phosphatase, receptor type, C0.149
Nrlneural retina leucine zipper0.149
Vat1vesicle amine transport protein 1 homolog (T californica)0.149
Fat2FAT tumor suppressor homolog 2 (Drosophila)0.146
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.145
Mpp3membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)0.144
Lyve1lymphatic vessel endothelial hyaluronan receptor 10.140
Capn6calpain 60.136
Pla2g5phospholipase A2, group V0.135
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.134
Fgd4FYVE, RhoGEF and PH domain containing 40.133
Sdc3syndecan 30.133
Loxlysyl oxidase0.132
Adam17ADAM metallopeptidase domain 170.132
Krt15keratin 150.131
Dab2disabled homolog 2 (Drosophila)0.131
Prl3a1Prolactin family 3, subfamily a, member 10.131
Nrg1neuregulin 10.131
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.127
Oxtroxytocin receptor0.127
Ptgs2prostaglandin-endoperoxide synthase 20.126
Npr3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)0.126
Galr3galanin receptor 30.125
Lig3ligase III, DNA, ATP-dependent0.124
Plod2procollagen lysine, 2-oxoglutarate 5-dioxygenase 20.122
Irx4iroquois homeobox 40.120
Ednraendothelin receptor type A0.119
Id3inhibitor of DNA binding 30.119
Bmp3bone morphogenetic protein 30.118
Dlx5distal-less homeobox 50.117
Cnga4cyclic nucleotide gated channel alpha 40.117
Cd40lgCD40 ligand0.116
Ahraryl hydrocarbon receptor0.116
Loxl1lysyl oxidase-like 10.116
Psgb1pregnancy-specific beta 1-glycoprotein0.114
Ageradvanced glycosylation end product-specific receptor0.111
Dctn4dynactin 40.111
Gata6GATA binding protein 60.111
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism