The network for 'embryonic pattern specification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

embryonic pattern specification

The process that results in the patterns of cell differentiation that will arise in an embryo.

NameDescriptionProbabilityFunc Analog Organism
unc-62Protein UNC-620.832
par-5Protein PAR-50.806
goa-1Protein GOA-10.566
egl-15Protein EGL-150.410
lin-45Protein LIN-450.354
egl-13Protein EGL-130.352
glp-1Protein GLP-10.328
let-60Protein LET-600.319
nhr-67Protein NHR-670.292
vav-1Protein VAV-10.275
lin-29Protein LIN-290.262
klp-15Protein KLP-150.238
elt-6Protein ELT-60.211
egl-30Protein EGL-300.204
mpk-1Protein MPK-10.196
oma-2Protein OMA-20.184
pal-1Protein PAL-10.169
hlh-1Protein HLH-10.168
hlh-30Protein HLH-300.167
mom-2Protein MOM-20.163
daf-12Protein DAF-120.157
sma-6Protein SMA-60.136
egl-18Protein EGL-180.132
lin-11Protein LIN-110.126
glh-1Protein GLH-10.125
zfp-1Protein ZFP-10.117
gpb-1Protein GPB-10.116
wrm-1Protein WRM-10.113
lin-7Protein LIN-70.113
ucr-2.3Protein UCR-2.30.110
rho-1Protein RHO-10.105
ain-1Protein AIN-10.105
pha-4Protein PHA-40.103
dnj-5Protein DNJ-50.099
sel-8Protein SEL-80.099
snr-3Protein SNR-30.096
cul-2Protein CUL-20.095
mcm-7Protein MCM-70.094
pop-1Protein POP-10.092
lin-3Protein LIN-30.092
pry-1Protein PRY-10.092
mex-5Protein MEX-50.089
lin-17Protein LIN-170.087
C50B8.1Protein C50B8.10.085
xpo-1Protein XPO-10.084
unc-43Protein UNC-430.082
fem-1Protein FEM-10.081
hrp-1Protein HRP-10.076
bar-1Protein BAR-10.075
nhr-25Protein NHR-250.074
ina-1Protein INA-10.073
ceh-20Protein CEH-200.071
unc-54Protein UNC-540.070
CELE_Y46G5A.29Protein Y46G5A.290.068
csnk-1Protein CSNK-10.066
CELE_C17H12.13Protein C17H12.130.066
lin-53Protein LIN-530.066
lin-66Protein LIN-660.062
syd-2Protein SYD-20.062
mcm-2Protein MCM-20.061
ztf-2Protein ZTF-20.060
ceh-27Protein CEH-270.059
cam-1Protein CAM-10.058
pept-3Protein PEPT-30.057
lsy-22Protein LSY-220.057
CELE_Y39E4B.2Protein Y39E4B.20.055
cey-1Protein CEY-10.054
lag-1Protein LAG-10.054
ceh-13Protein CEH-130.052
egl-5Protein EGL-50.049
snr-4Protein SNR-40.048
glh-2Protein GLH-20.048
bli-1Protein BLI-10.048
mex-6Protein MEX-60.047
madf-5Protein MADF-50.047
eef-1A.1Protein EEF-1A.10.046
unc-53Protein UNC-530.046
eor-2Protein EOR-20.045
xpo-2Protein XPO-20.045
ZK265.6Protein ZK265.60.044
zyg-11Protein ZYG-110.042
tbb-4Protein TBB-40.042
spk-1Protein SPK-10.039
sel-12Protein SEL-120.038
gpd-4Protein GPD-40.038
dcap-1Protein DCAP-10.037
zfp-3Protein ZFP-30.037
cwn-1Protein CWN-10.037
ikb-1Protein IKB-10.037
dsh-2Protein DSH-20.037
ten-1Protein TEN-10.036
prg-2Protein PRG-20.036
rsa-1Protein RSA-10.036
rpa-2Protein RPA-20.035
cec-6Protein CEC-60.035
C34F6.9Protein C34F6.90.035
him-17Protein HIM-170.035
clp-4Protein CLP-40.034
W03F8.4Protein W03F8.40.034
zif-1Protein ZIF-10.033
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
bmp4bone morphogenetic protein 40.987
notch1anotch homolog 1a0.973
lef1lymphocyte enhancer binding factor 10.967
tbx1T-box 10.965
tbx16T-box gene 160.929
wnt1wingless-type MMTV integration site family, member 10.903
fgf10afibroblast growth factor 10a0.889
shhasonic hedgehog a0.879
pax7apaired box gene 7a0.869
tp53tumor protein p530.770
fgf3fibroblast growth factor 30.767
cdh2cadherin 2, neuronal0.732
tbx20T-box 200.598
ca15bcarbonic anhydrase XV b0.585
myod1myogenic differentiation 10.574
wnt9awingless-type MMTV integration site family, member 9A0.564
spry4sprouty (Drosophila) homolog 40.545
oepone-eyed pinhead0.539
snai1bsnail homolog 1b (Drosophila)0.538
neurog1neurogenin 10.536
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.536
nanos3nanos homolog 30.530
aplnrbapelin receptor b0.508
lamb1alaminin, beta 1a0.495
rx2retinal homeobox gene 20.478
ptf1apancreas specific transcription factor, 1a0.446
mespamesoderm posterior a0.440
epb4.1l4erythrocyte protein band 4.1-like 40.430
fezf2FEZ family zinc finger 20.398
pax2apaired box gene 2a0.387
pea3ETS-domain transcription factor pea30.385
wnt8bwingless-type MMTV integration site family, member 8b0.380
six3asine oculis homeobox homolog 3a0.374
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.372
wnt2bbwingless-type MMTV integration site family, member 2Bb0.368
wnt11wingless-type MMTV integration site family, member 110.350
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.339
gro2groucho 20.339
col2a1acollagen type II, alpha-1a0.324
unc45bunc-45 homolog B (C. elegans)0.315
tgfb3transforming growth factor, beta 30.314
fgf17fibroblast growth factor 170.305
mecomMDS1 and EVI1 complex locus0.294
gyltl1bglycosyltransferase-like 1b0.292
has2hyaluronan synthase 20.289
cdc42cell division cycle 420.284
hey2hairy/enhancer-of-split related with YRPW motif 20.283
lamc1laminin, gamma 10.266
six4bsine oculis homeobox homolog 4b0.257
prkczprotein kinase C, zeta0.255
ndr2nodal-related 20.253
hnf1baHNF1 homeobox Ba0.253
pou5f1POU domain, class 5, transcription factor 10.253
wnt4awingless-type MMTV integration site family, member 4a0.249
foxd3forkhead box D30.248
tll1tolloid-like 10.247
nrp1bneuropilin 1b0.246
elavl2ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)0.242
snai1asnail homolog 1a (Drosophila)0.235
sox9bSRY-box containing gene 9b0.229
ventventral expressed homeobox0.228
myhz2myosin, heavy polypeptide 2, fast muscle specific0.228
myf5myogenic factor 50.226
hand2heart and neural crest derivatives expressed transcript 20.224
spsb4asplA/ryanodine receptor domain and SOCS box containing 4a0.223
gro1groucho 10.218
mpp5amembrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)0.217
gli1GLI-Kruppel family member 10.214
ephb4beph receptor B4b0.213
acvr1bactivin A receptor, type IB0.212
her7hairy and enhancer of split related-70.212
jag2jagged 20.202
pcdh8protocadherin 80.201
lhx1bLIM homeobox 1b0.200
sox32SRY-box containing gene 320.197
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.195
bmp2abone morphogenetic protein 2a0.191
nipblbnovel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)0.187
dusp6dual specificity phosphatase 60.185
wnt9bwingless-type MMTV integration site family, member 9B0.185
wnt7aawingless-type MMTV integration site family, member 7Aa0.180
ptch2patched 20.178
sox17SRY-box containing gene 170.175
gata3GATA-binding protein 30.174
tcf7l1atranscription factor 7-like 1a (T-cell specific, HMG-box)0.172
gli2aGLI-Kruppel family member GLI2a0.171
msgn1mesogenin 10.171
bambiaBMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a0.169
pax8paired box gene 80.165
flot1bflotillin 1b0.161
hoxd4ahomeo box D4a0.158
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
magomago nashi0.997
aPKCatypical protein kinase C0.997
ftz-f1ftz transcription factor 10.995
eyaeyes absent0.994
BicDBicaudal D0.984
Ras85DRas oncogene at 85D0.976
Hel25EHelicase at 25E0.974
Hrb27CHeterogeneous nuclear ribonucleoprotein at 27C0.961
phlpole hole0.960
traltrailer hitch0.945
Myd88CG2078 gene product from transcript CG2078-RA0.944
slp1sloppy paired 10.902
EgfrEpidermal growth factor receptor0.897
gbbglass bottom boat0.892
par-1CG8201 gene product from transcript CG8201-RA0.890
DadDaughters against dpp0.883
SosSon of sevenless0.869
Dcp1Decapping protein 10.858
Ets97DEts at 97D0.825
slmbsupernumerary limbs0.801
Src64BSrc oncogene at 64B0.779
Rac1CG2248 gene product from transcript CG2248-RA0.765
Mef2Myocyte enhancer factor 20.756
gcmglial cells missing0.745
opaodd paired0.733
CG6854CG6854 gene product from transcript CG6854-RC0.730
raspCG11495 gene product from transcript CG11495-RA0.722
argosCG4531 gene product from transcript CG4531-RA0.715
TER94CG2331 gene product from transcript CG2331-RA0.711
aopanterior open0.698
ovoCG6824 gene product from transcript CG6824-RE0.679
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.669
sec5CG8843 gene product from transcript CG8843-RA0.658
Gprk2G protein-coupled receptor kinase 20.629
stumpsCG31317 gene product from transcript CG31317-RC0.627
CG4771CG4771 gene product from transcript CG4771-RA0.624
bratbrain tumor0.618
salmspalt major0.604
par-6CG5884 gene product from transcript CG5884-RA0.592
me31Bmaternal expression at 31B0.586
Wnt4Wnt oncogene analog 40.578
CkIalphaCasein kinase Ialpha0.571
hydhyperplastic discs0.569
ksrkinase suppressor of ras0.554
lolalongitudinals lacking0.544
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.992
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.795
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.681
EIF4A3eukaryotic translation initiation factor 4A30.400
SMAD3SMAD family member 30.314
GSK3Bglycogen synthase kinase 3 beta0.246
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.190
NPM1nucleophosmin (nucleolar phosphoprotein B23, numatrin)0.158
YAP1Yes-associated protein 10.157
SMURF2SMAD specific E3 ubiquitin protein ligase 20.145
SMAD2SMAD family member 20.144
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.128
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.127
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.122
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.114
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.111
SNAP25synaptosomal-associated protein, 25kDa0.108
EGFRepidermal growth factor receptor0.106
HDAC1histone deacetylase 10.099
WDR5WD repeat domain 50.088
PTPN1protein tyrosine phosphatase, non-receptor type 10.086
RBL2retinoblastoma-like 2 (p130)0.072
HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)0.066
OCRLoculocerebrorenal syndrome of Lowe0.066
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.062
USP11ubiquitin specific peptidase 110.061
NOTCH1notch 10.059
MAPTmicrotubule-associated protein tau0.056
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.055
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.052
PCGF2polycomb group ring finger 20.051
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.051
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.050
BMPR1Abone morphogenetic protein receptor, type IA0.046
CDC27cell division cycle 27 homolog (S. cerevisiae)0.043
HNRNPCheterogeneous nuclear ribonucleoprotein C (C1/C2)0.041
SMAD1SMAD family member 10.039
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.038
IQGAP1IQ motif containing GTPase activating protein 10.036
MAP3K3mitogen-activated protein kinase kinase kinase 30.036
TNRC6Atrinucleotide repeat containing 6A0.034
SMAD7SMAD family member 70.034
PICALMphosphatidylinositol binding clathrin assembly protein0.034
PRKCZprotein kinase C, zeta0.033
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.032
RING1ring finger protein 10.031
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.030
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.030
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.028
HIPK2homeodomain interacting protein kinase 20.027
JAG1jagged 10.025
CUL2cullin 20.024
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.024
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.023
CUL4Acullin 4A0.023
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.023
ARAFv-raf murine sarcoma 3611 viral oncogene homolog0.023
PCGF3polycomb group ring finger 30.022
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.020
PTENphosphatase and tensin homolog0.020
NOTCH3notch 30.019
NCOA6nuclear receptor coactivator 60.019
TGFB1transforming growth factor, beta 10.019
VEGFAvascular endothelial growth factor A0.019
BMP1bone morphogenetic protein 10.018
TP53tumor protein p530.018
CAND1cullin-associated and neddylation-dissociated 10.018
ESR1estrogen receptor 10.017
CENPJcentromere protein J0.017
ZFYVE9zinc finger, FYVE domain containing 90.017
CCND1cyclin D10.017
INSRinsulin receptor0.017
GDAguanine deaminase0.016
NXF1nuclear RNA export factor 10.016
PTPN11protein tyrosine phosphatase, non-receptor type 110.016
SCHIP1schwannomin interacting protein 10.016
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.016
PBX1pre-B-cell leukemia homeobox 10.015
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.015
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.015
PRKCIprotein kinase C, iota0.015
CHD8chromodomain helicase DNA binding protein 80.015
IL4Rinterleukin 4 receptor0.015
FGFR1fibroblast growth factor receptor 10.015
KEAP1kelch-like ECH-associated protein 10.014
SPENspen homolog, transcriptional regulator (Drosophila)0.014
APCadenomatous polyposis coli0.014
FGF10fibroblast growth factor 100.014
TNRC6Btrinucleotide repeat containing 6B0.014
CBX4chromobox homolog 40.013
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.013
ANAPC1anaphase promoting complex subunit 10.013
FGF1fibroblast growth factor 1 (acidic)0.013
RBX1ring-box 1, E3 ubiquitin protein ligase0.013
PKP2plakophilin 20.013
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.012
SOCS1suppressor of cytokine signaling 10.012
FZD1frizzled homolog 1 (Drosophila)0.012
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Mapre1microtubule-associated protein, RP/EB family, member 10.254
Ptprcprotein tyrosine phosphatase, receptor type, C0.234
Gnai3guanine nucleotide binding protein (G protein), alpha inhibiting 30.211
Syn1synapsin I0.189
Hnrnpabheterogeneous nuclear ribonucleoprotein A/B0.178
Dlg4discs, large homolog 4 (Drosophila)0.155
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.152
Tle4transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)0.148
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.148
Syt4synaptotagmin IV0.147
Nek9NIMA (never in mitosis gene a)- related kinase 90.136
Rac1ras-related C3 botulinum toxin substrate 10.131
Elk3ELK3, ETS-domain protein0.125
Rnps1ribonucleic acid binding protein S10.119
Rararetinoic acid receptor, alpha0.099
Caskcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.095
Snap25synaptosomal-associated protein 250.094
Prph2peripherin 20.094
Pak2p21 protein (Cdc42/Rac)-activated kinase 20.093
Emp1epithelial membrane protein 10.092
Tpm4tropomyosin 40.090
Rnf4ring finger protein 40.089
Tcf12transcription factor 120.086
Fusfusion (involved in t(12;16) in malignant liposarcoma) (human)0.084
Tgfbr2transforming growth factor, beta receptor II0.081
Bmp7bone morphogenetic protein 70.081
Clic4chloride intracellular channel 40.081
Ctxn1cortexin 10.079
Myl9myosin, light chain 9, regulatory0.079
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.078
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.077
Rbbp7retinoblastoma binding protein 70.074
Arntaryl hydrocarbon receptor nuclear translocator0.073
NsfN-ethylmaleimide-sensitive factor0.072
Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.071
Gata6GATA binding protein 60.071
Pcnaproliferating cell nuclear antigen0.069
Lamc1laminin, gamma 10.066
Dgkidiacylglycerol kinase, iota0.064
Rap1bRAP1B, member of RAS oncogene family0.064
Azin1antizyme inhibitor 10.064
Eef1e1eukaryotic translation elongation factor 1 epsilon 10.063
Mapk9mitogen-activated protein kinase 90.062
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.061
Myh9myosin, heavy chain 9, non-muscle0.060
Chrm3cholinergic receptor, muscarinic 30.060
Ube2aubiquitin-conjugating enzyme E2A (RAD6 homolog)0.060
Ppp2cbprotein phosphatase 2, catalytic subunit, beta isoform0.059
Actr3ARP3 actin-related protein 3 homolog (yeast)0.058
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.058
Dgkzdiacylglycerol kinase zeta0.058
Gata3GATA binding protein 30.057
Hnrnpfheterogeneous nuclear ribonucleoprotein F0.055
Bnip2BCL2/adenovirus E1B interacting protein 20.055
Smad1SMAD family member 10.055
Arpc2actin related protein 2/3 complex, subunit 20.054
Pctk1PCTAIRE protein kinase 10.054
Actbactin, beta0.053
Apcadenomatous polyposis coli0.052
Gna12guanine nucleotide binding protein (G protein) alpha 120.052
Arf6ADP-ribosylation factor 60.052
Atf2activating transcription factor 20.052
Ctnnd2catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)0.052
Sh3gl2SH3-domain GRB2-like 20.052
Pafah1b2platelet-activating factor acetylhydrolase, isoform 1b, subunit 20.052
Golph3golgi phosphoprotein 3 (coat-protein)0.051
Pecam1platelet/endothelial cell adhesion molecule 10.051
Capza2capping protein (actin filament) muscle Z-line, alpha 20.050
Wbp11WW domain binding protein 110.050
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.050
Sema3asema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A0.050
Map6microtubule-associated protein 60.050
RGD1306404similar to mKIAA1402 protein0.049
Elavl4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)0.049
Atp6v0a1ATPase, H+ transporting, lysosomal V0 subunit A10.049
Strnstriatin, calmodulin binding protein0.049
Jtbjumping translocation breakpoint0.049
Irf2interferon regulatory factor 20.048
Gnazguanine nucleotide binding protein (G protein), alpha z polypeptide0.047
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.047
Metmet proto-oncogene0.046
Tpm3tropomyosin 3, gamma0.046
Sirpasignal-regulatory protein alpha0.045
Cd82Cd82 molecule0.045
Foxc2forkhead box C20.045
Twist2twist homolog 2 (Drosophila)0.045
Arhgap4Rho GTPase activating protein 40.045
Acta1actin, alpha 1, skeletal muscle0.044
Dact3dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)0.044
Akirin2akirin 20.044
Pkiaprotein kinase (cAMP-dependent, catalytic) inhibitor alpha0.044
Nab1Ngfi-A binding protein 10.044
Slco2a1solute carrier organic anion transporter family, member 2a10.044
Ifrd1interferon-related developmental regulator 10.043
Ppp6cprotein phosphatase 6, catalytic subunit0.043
Senp2Sumo1/sentrin/SMT3 specific peptidase 20.043
Prss22protease, serine, 220.043
Lig3ligase III, DNA, ATP-dependent0.043
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism