The network for 'unsaturated fatty acid metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

unsaturated fatty acid metabolic process

The chemical reactions and pathways involving an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.

NameDescriptionProbabilityFunc Analog Organism
elo-5Protein ELO-50.709
acs-22Protein ACS-220.573
ugt-22Protein UGT-220.518
fat-2Protein FAT-20.481
elo-2Protein ELO-20.418
cyp-35C1Protein CYP-35C10.246
cyp-35A2Protein CYP-35A20.231
fat-4Protein FAT-40.223
CELE_Y43F8C.13Protein Y43F8C.130.202
CELE_C29F7.2Protein C29F7.20.148
ant-1.1Protein ANT-1.10.147
cyp-35A3Protein CYP-35A30.146
fat-6Protein FAT-60.125
elo-6Protein ELO-60.108
C44C1.5Protein C44C1.50.081
C15C8.3Protein C15C8.30.077
cth-2Protein CTH-20.070
acs-1Protein ACS-10.069
ZK688.3Protein ZK688.30.067
F08A8.4Protein F08A8.40.059
cyp-35A4Protein CYP-35A40.055
T28D9.3Protein T28D9.30.053
hpo-8Protein HPO-80.043
cyp-35A5Protein CYP-35A50.037
F35C8.5Protein F35C8.50.032
F13H6.3Protein F13H6.30.032
T02G5.7Protein T02G5.70.030
CELE_ZK550.6Protein ZK550.60.027
F58F9.7Protein F58F9.70.026
cept-1Protein CEPT-10.025
Y48E1B.8Protein Y48E1B.80.025
sptl-3Protein SPTL-30.024
F57F5.1Protein F57F5.10.023
pmt-1Protein PMT-10.020
T15B7.1Protein T15B7.10.019
pas-5Protein PAS-50.018
CELE_Y105E8B.5Protein Y105E8B.50.017
fat-1Protein FAT-10.017
pes-9Protein PES-90.017
sur-5Protein SUR-50.016
CELE_F25B4.1Protein F25B4.10.016
F08G5.6Protein F08G5.60.015
dhs-20Protein DHS-200.015
ugt-25Protein UGT-250.014
hrg-4Protein HRG-40.014
R74.7Protein R74.70.013
cyp-43A1Protein CYP-43A10.013
best-13Protein BEST-130.012
unc-24Protein UNC-240.012
cpz-2Protein CPZ-20.011
CELE_T07G12.3Protein T07G12.30.011
nlr-1Protein NLR-10.010
ubc-19Protein UBC-190.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.987
NCF4neutrophil cytosolic factor 4, 40kDa0.973
GGT1gamma-glutamyltransferase 10.957
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.956
GGTLC1gamma-glutamyltransferase light chain 10.857
DHCR77-dehydrocholesterol reductase0.821
CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 60.579
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.570
COTL1coactosin-like 1 (Dictyostelium)0.498
CYP4A11cytochrome P450, family 4, subfamily A, polypeptide 110.426
MAPK1mitogen-activated protein kinase 10.380
CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 90.303
TICAM2toll-like receptor adaptor molecule 20.298
MAP2K4mitogen-activated protein kinase kinase 40.270
HLA-DPA1major histocompatibility complex, class II, DP alpha 10.267
GGT2gamma-glutamyltransferase 20.254
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.223
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.222
HLA-DQA1major histocompatibility complex, class II, DQ alpha 10.192
PDPK13-phosphoinositide dependent protein kinase-10.175
CYP4F2cytochrome P450, family 4, subfamily F, polypeptide 20.173
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.159
CYP2B6cytochrome P450, family 2, subfamily B, polypeptide 60.153
CYP4F12cytochrome P450, family 4, subfamily F, polypeptide 120.139
DUSP1dual specificity phosphatase 10.138
HLA-DRB5major histocompatibility complex, class II, DR beta 50.125
CYBAcytochrome b-245, alpha polypeptide0.124
CYP2C19cytochrome P450, family 2, subfamily C, polypeptide 190.121
HLA-DMAmajor histocompatibility complex, class II, DM alpha0.115
CYP4F3cytochrome P450, family 4, subfamily F, polypeptide 30.108
LY96lymphocyte antigen 960.105
C8Bcomplement component 8, beta polypeptide0.105
PPIDpeptidylprolyl isomerase D0.097
CYP3A43cytochrome P450, family 3, subfamily A, polypeptide 430.095
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.095
CXCR4chemokine (C-X-C motif) receptor 40.094
ALOX5arachidonate 5-lipoxygenase0.094
PRDX1peroxiredoxin 10.092
CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 40.082
NCF2neutrophil cytosolic factor 20.075
PRKCBprotein kinase C, beta0.068
HLA-DRB1major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 10.067
CYP2C18cytochrome P450, family 2, subfamily C, polypeptide 180.064
MAPK8mitogen-activated protein kinase 80.058
CACYBPcalcyclin binding protein0.057
C8Acomplement component 8, alpha polypeptide0.056
GLYATglycine-N-acyltransferase0.056
LAMC3laminin, gamma 30.055
HLA-DMBmajor histocompatibility complex, class II, DM beta0.054
SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.054
ALOX5AParachidonate 5-lipoxygenase-activating protein0.051
XPO7exportin 70.051
TPSB2tryptase beta 2 (gene/pseudogene)0.048
NQO1NAD(P)H dehydrogenase, quinone 10.047
CYP4F11cytochrome P450, family 4, subfamily F, polypeptide 110.047
CPA3carboxypeptidase A3 (mast cell)0.044
HMGCS23-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)0.044
F9coagulation factor IX0.043
FETUBfetuin B0.043
TRIM9tripartite motif containing 90.043
PRKCDprotein kinase C, delta0.042
HLA-DPB1major histocompatibility complex, class II, DP beta 10.041
OTCornithine carbamoyltransferase0.041
SULT2B1sulfotransferase family, cytosolic, 2B, member 10.040
ABCC3ATP-binding cassette, sub-family C (CFTR/MRP), member 30.040
C6complement component 60.040
ADH6alcohol dehydrogenase 6 (class V)0.040
CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 10.040
CHORDC1cysteine and histidine-rich domain (CHORD) containing 10.040
AADACarylacetamide deacetylase (esterase)0.039
FKBP4FK506 binding protein 4, 59kDa0.037
TNFSF11tumor necrosis factor (ligand) superfamily, member 110.037
ACACAacetyl-CoA carboxylase alpha0.036
KNG1kininogen 10.036
TALDO1transaldolase 10.036
AGXT2alanine--glyoxylate aminotransferase 20.034
HRGhistidine-rich glycoprotein0.034
UGT1A3UDP glucuronosyltransferase 1 family, polypeptide A30.034
SULT1B1sulfotransferase family, cytosolic, 1B, member 10.033
ABCC2ATP-binding cassette, sub-family C (CFTR/MRP), member 20.033
DAOD-amino-acid oxidase0.032
FABP1fatty acid binding protein 1, liver0.032
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha0.031
G6PCglucose-6-phosphatase, catalytic subunit0.031
EP300E1A binding protein p3000.031
MAT1Amethionine adenosyltransferase I, alpha0.031
HALhistidine ammonia-lyase0.030
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.030
AHSA1AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)0.030
SLPIsecretory leukocyte peptidase inhibitor0.030
PDZK1IP1PDZK1 interacting protein 10.030
ZHX1zinc fingers and homeoboxes 10.030
FGL1fibrinogen-like 10.029
AKR1C4aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)0.029
AKR1B10aldo-keto reductase family 1, member B10 (aldose reductase)0.028
HPD4-hydroxyphenylpyruvate dioxygenase0.028
KIAA1712KIAA17120.028
RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 20.028
GBA3glucosidase, beta, acid 3 (cytosolic)0.028
MS4A2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.027
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Cyp2c29cytochrome P450, family 2, subfamily c, polypeptide 290.947
Cyp2c38cytochrome P450, family 2, subfamily c, polypeptide 380.924
Cps1carbamoyl-phosphate synthetase 10.893
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.868
Cyp3a11cytochrome P450, family 3, subfamily a, polypeptide 110.851
Alox5arachidonate 5-lipoxygenase0.831
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.770
Cyp2b10cytochrome P450, family 2, subfamily b, polypeptide 100.704
Cyp2c50cytochrome P450, family 2, subfamily c, polypeptide 500.621
Alox5aparachidonate 5-lipoxygenase activating protein0.600
Cyp2c54cytochrome P450, family 2, subfamily c, polypeptide 540.589
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.582
Hrghistidine-rich glycoprotein0.574
Cyp2b9cytochrome P450, family 2, subfamily b, polypeptide 90.566
Cyp4a14cytochrome P450, family 4, subfamily a, polypeptide 140.537
Otcornithine transcarbamylase0.478
Cyp3a13cytochrome P450, family 3, subfamily a, polypeptide 130.448
Sult1d1sulfotransferase family 1D, member 10.419
H2-Aahistocompatibility 2, class II antigen A, alpha0.400
Cyp2a12cytochrome P450, family 2, subfamily a, polypeptide 120.370
Clockcircadian locomotor output cycles kaput0.356
Serpina1cserine (or cysteine) peptidase inhibitor, clade A, member 1C0.355
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.354
Cyp2c70cytochrome P450, family 2, subfamily c, polypeptide 700.348
Cyp3a25cytochrome P450, family 3, subfamily a, polypeptide 250.332
Cd14CD14 antigen0.331
Hsd3b3hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 30.305
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.290
Mbl2mannose-binding lectin (protein C) 20.289
Keg1kidney expressed gene 10.287
F13bcoagulation factor XIII, beta subunit0.287
Cyp2f2cytochrome P450, family 2, subfamily f, polypeptide 20.286
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.281
Aadacarylacetamide deacetylase (esterase)0.277
Csf1rcolony stimulating factor 1 receptor0.277
Nr1i2nuclear receptor subfamily 1, group I, member 20.276
TyrobpTYRO protein tyrosine kinase binding protein0.276
Baatbile acid-Coenzyme A: amino acid N-acyltransferase0.267
F9coagulation factor IX0.260
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.251
Cyp2b13cytochrome P450, family 2, subfamily b, polypeptide 130.247
Pon1paraoxonase 10.246
Sult1b1sulfotransferase family 1B, member 10.246
Serpina6serine (or cysteine) peptidase inhibitor, clade A, member 60.235
Hsd3b2hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 20.233
Cyp8b1cytochrome P450, family 8, subfamily b, polypeptide 10.230
Cyp2c39cytochrome P450, family 2, subfamily c, polypeptide 390.220
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.219
Adh7alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide0.214
Aldobaldolase B, fructose-bisphosphate0.212
Ces1dcarboxylesterase 1D0.206
Gsta2glutathione S-transferase, alpha 2 (Yc2)0.198
Prlrprolactin receptor0.197
Apoc4apolipoprotein C-IV0.194
Cdsncorneodesmosin0.194
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.193
Cyp2d9cytochrome P450, family 2, subfamily d, polypeptide 90.192
Rdh7retinol dehydrogenase 70.189
Tdo2tryptophan 2,3-dioxygenase0.186
Hmgcs23-hydroxy-3-methylglutaryl-Coenzyme A synthase 20.182
Cml2camello-like 20.177
Cyp2d10cytochrome P450, family 2, subfamily d, polypeptide 100.170
H2-DMahistocompatibility 2, class II, locus DMa0.170
Bchebutyrylcholinesterase0.169
Ces2acarboxylesterase 2A0.166
Krtap6-1keratin associated protein 6-10.166
Pplperiplakin0.166
G6pcglucose-6-phosphatase, catalytic0.165
H2-Eb1histocompatibility 2, class II antigen E beta0.165
Cd22CD22 antigen0.161
Akr1c6aldo-keto reductase family 1, member C60.160
CrpC-reactive protein, pentraxin-related0.159
Rag1recombination activating gene 10.157
Cyp2c37cytochrome P450, family 2. subfamily c, polypeptide 370.157
Albalbumin0.153
Krt72-pskeratin 72, pseudogene0.145
Orai1ORAI calcium release-activated calcium modulator 10.141
Ugt3a2UDP glycosyltransferases 3 family, polypeptide A20.138
Arandrogen receptor0.137
Gsta3glutathione S-transferase, alpha 30.132
Akr1d1aldo-keto reductase family 1, member D10.132
Esr1estrogen receptor 1 (alpha)0.132
Elovl3elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 30.131
Cyp4b1cytochrome P450, family 4, subfamily b, polypeptide 10.131
Ptgs1prostaglandin-endoperoxide synthase 10.131
C1qbcomplement component 1, q subcomponent, beta polypeptide0.130
Defb1defensin beta 10.125
Mup5major urinary protein 50.124
Ptgs2prostaglandin-endoperoxide synthase 20.123
Uoxurate oxidase0.121
Apohapolipoprotein H0.121
Ch25hcholesterol 25-hydroxylase0.120
Ugt2a3UDP glucuronosyltransferase 2 family, polypeptide A30.118
Vsig4V-set and immunoglobulin domain containing 40.118
Adh1alcohol dehydrogenase 1 (class I)0.117
Hgdhomogentisate 1, 2-dioxygenase0.116
Mat1amethionine adenosyltransferase I, alpha0.112
Cyp4a31cytochrome P450, family 4, subfamily a, polypeptide 310.111
Il17ainterleukin 17A0.111
Dmgdhdimethylglycine dehydrogenase precursor0.110
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Akr1c18aldo-keto reductase family 1, member C180.777
Cyp2d2cytochrome P450, family 2, subfamily d, polypeptide 20.768
Cyp2d4cytochrome P450, family 2, subfamily d, polypeptide 40.664
Abcc6ATP-binding cassette, subfamily C (CFTR/MRP), member 60.631
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.580
Cyp2b1cytochrome P450, family 2, subfamily b, polypeptide 10.481
Reg3gregenerating islet-derived 3 gamma0.478
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.403
Sult1e1sulfotransferase family 1E, estrogen-preferring, member 10.399
Cyp4a10cytochrome P450, family 4, subfamily a, polypeptide 100.379
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.360
Cyp2c13cytochrome P450, family 2, subfamily c, polypeptide 130.359
Sult1c3sulfotransferase family, cytosolic, 1C, member 30.328
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.309
A1i3alpha-1-inhibitor III0.298
Lgals3lectin, galactoside-binding, soluble, 30.292
Ctdsp1CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 10.279
Cyp2d3cytochrome P450, family 2, subfamily d, polypeptide 30.277
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.270
Cyp4a8cytochrome P450, family 4, subfamily a, polypeptide 80.250
Tspotranslocator protein0.243
Opn1mwopsin 1 (cone pigments), medium-wave-sensitive0.242
S100a11S100 calcium binding protein A11 (calizzarin)0.240
Abcb11ATP-binding cassette, subfamily B (MDR/TAP), member 110.239
Cyp2b2cytochrome P450, family 2, subfamily b, polypeptide 20.231
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.229
Cyp2b15cytochrome P450, family 2, subfamily b, polypeptide 150.202
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.202
Cyp2c22cytochrome P450, family 2, subfamily c, polypeptide 220.197
Slc14a2solute carrier family 14 (urea transporter), member 20.173
Sult1c2sulfotransferase family, cytosolic, 1C, member 20.168
Aqp9aquaporin 90.164
Rxrgretinoid X receptor gamma0.163
Slc6a2solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 20.163
Gckrglucokinase (hexokinase 4) regulator0.147
Orm1orosomucoid 10.144
Crygfcrystallin, gamma F0.133
Cyp4a2cytochrome P450, family 4, subfamily a, polypeptide 20.132
Gfapglial fibrillary acidic protein0.126
Apobapolipoprotein B0.125
Adh1alcohol dehydrogenase 1 (class I)0.122
Serpinb3serine protease inhibitor B30.114
Gsta5glutathione S-transferase Yc2 subunit0.108
Hspb1heat shock protein 10.105
Rag1recombination activating gene 10.104
Serpina4serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 40.102
Cyp4f4cytochrome P450, family 4, subfamily f, polypeptide 40.102
Olr1701olfactory receptor 17010.096
Tpbpatrophoblast specific protein alpha0.095
S100a6S100 calcium binding protein A60.093
Cyp7a1cytochrome P450, family 7, subfamily a, polypeptide 10.089
Cyp1a1cytochrome P450, family 1, subfamily a, polypeptide 10.089
Dnase1deoxyribonuclease I0.086
Cyp27a1cytochrome P450, family 27, subfamily a, polypeptide 10.086
Ctnna1catenin (cadherin associated protein), alpha 10.086
Cyp3a23/3a1cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 10.085
Cyp4b1cytochrome P450, family 4, subfamily b, polypeptide 10.083
Inmtindolethylamine N-methyltransferase0.082
Scnn1bsodium channel, nonvoltage-gated 1, beta0.080
Hbbhemoglobin, beta0.079
Il17reinterleukin 17 receptor E0.079
Xdhxanthine dehydrogenase0.078
Crybb1crystallin, beta B10.078
Cyp2a2cytochrome P450, family 2, subfamily a, polypeptide 20.077
Vimvimentin0.076
Fmo1flavin containing monooxygenase 10.076
Ctla2acytotoxic T lymphocyte-associated protein 2 alpha0.073
Slc22a8solute carrier family 22 (organic anion transporter), member 80.073
Dpysdihydropyrimidinase0.071
Cybrd1cytochrome b reductase 10.069
Cyp1b1cytochrome P450, family 1, subfamily b, polypeptide 10.069
Fdxrferredoxin reductase0.068
LOC494499LOC494499 protein0.067
Sult1a1sulfotransferase family, cytosolic, 1A, phenol-preferring, member 10.067
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.067
Ifit1interferon-induced protein with tetratricopeptide repeats 10.067
Pvrl4poliovirus receptor-related 40.061
Mef2dmyocyte enhancer factor 2D0.061
Prlrprolactin receptor0.061
Hsd3b5hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 50.060
Olr1362olfactory receptor 13620.060
Anxa2annexin A20.060
Slco2b1solute carrier organic anion transporter family, member 2b10.060
Cst8cystatin 8 (cystatin-related epididymal specific)0.059
Atp4bATPase, H+/K+ exchanging, beta polypeptide0.059
RT1-BbRT1 class II, locus Bb0.057
Gja5gap junction protein, alpha 50.055
LOC100361547Cytochrome P450, family 2, subfamily c, polypeptide 7-like0.055
Serpina1serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10.054
Fgfr4fibroblast growth factor receptor 40.053
Ces1ecarboxylesterase 1E0.053
Ccl20chemokine (C-C motif) ligand 200.052
F9coagulation factor IX0.052
Ppargperoxisome proliferator-activated receptor gamma0.052
Cyp27b1cytochrome P450, family 27, subfamily b, polypeptide 10.052
Prss1protease, serine, 1 (trypsin 1)0.051
Akr1c12aldo-keto reductase family 1, member C120.050
Cyp2f4cytochrome P450, family 2, subfamily f, polypeptide 40.049
Acsm5acyl-CoA synthetase medium-chain family member 50.048
Dpep1dipeptidase 1 (renal)0.048
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism