The network for 'axon development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

axon development

The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation).

NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.988
pry-1Protein PRY-10.921
unc-73Protein UNC-730.888
ten-1Protein TEN-10.876
unc-40Protein UNC-400.863
pha-4Protein PHA-40.857
hbl-1Protein HBL-10.842
mab-5Protein MAB-50.830
syg-1Protein SYG-10.791
egl-13Protein EGL-130.771
mpk-1Protein MPK-10.756
sem-5Protein SEM-50.750
egl-46Protein EGL-460.735
rig-6Protein RIG-60.702
cam-1Protein CAM-10.693
hlh-1Protein HLH-10.684
ceh-20Protein CEH-200.684
unc-70Protein UNC-700.679
trim-9Protein TRIM-90.678
nhr-67Protein NHR-670.661
daf-11Protein DAF-110.661
unc-62Protein UNC-620.651
hlh-2Protein HLH-20.629
Y44E3A.6Protein Y44E3A.60.608
vab-3Protein VAB-30.595
egl-5Protein EGL-50.577
sli-1Protein SLI-10.575
vab-10Protein VAB-100.569
egl-15Protein EGL-150.563
mom-2Protein MOM-20.561
mec-4Protein MEC-40.550
unc-53Protein UNC-530.531
bar-1Protein BAR-10.523
unc-43Protein UNC-430.518
let-60Protein LET-600.517
T27A3.1Protein T27A3.10.516
unc-52Protein UNC-520.508
elt-6Protein ELT-60.497
pal-1Protein PAL-10.490
sma-6Protein SMA-60.483
lin-29Protein LIN-290.469
ncam-1Protein NCAM-10.462
tax-4Protein TAX-40.461
fkh-2Protein FKH-20.458
egl-27Protein EGL-270.436
npp-4Protein NPP-40.435
unc-42Protein UNC-420.430
ceh-48Protein CEH-480.425
pop-1Protein POP-10.417
tag-163Protein TAG-1630.415
mig-5Protein MIG-50.414
nhr-25Protein NHR-250.407
egl-8Protein EGL-80.400
rpn-6.1Protein RPN-6.10.382
sel-12Protein SEL-120.373
daf-12Protein DAF-120.371
mig-2Protein MIG-20.364
peb-1Protein PEB-10.364
dpl-1Protein DPL-10.353
syg-2Protein SYG-20.340
cdc-42Protein CDC-420.302
enu-3Protein ENU-30.301
lin-59Protein LIN-590.299
pdfr-1Protein PDFR-10.298
chd-7Protein CHD-70.298
ain-1Protein AIN-10.297
lin-17Protein LIN-170.296
ina-1Protein INA-10.295
unc-98Protein UNC-980.294
eat-18Protein EAT-180.293
hmg-1.2Protein HMG-1.20.293
unc-120Protein UNC-1200.292
ida-1Protein IDA-10.292
lsy-2Protein LSY-20.292
ptc-1Protein PTC-10.282
lag-1Protein LAG-10.282
unc-44Protein UNC-440.278
lin-12Protein LIN-120.274
dve-1Protein DVE-10.274
tmc-2Protein TMC-20.265
epi-1Protein EPI-10.262
unc-6Protein UNC-60.261
sad-1Protein SAD-10.261
egl-44Protein EGL-440.261
egl-30Protein EGL-300.259
lin-11Protein LIN-110.258
pkg-1Protein PKG-10.257
sax-7Protein SAX-70.255
tbc-2Protein TBC-20.253
let-268Protein LET-2680.250
unc-9Protein UNC-90.249
gld-1Protein GLD-10.249
ntl-4Protein NTL-40.246
B0361.8Protein B0361.80.241
R10E12.2Protein R10E12.20.237
emb-9Protein EMB-90.231
cls-2Protein CLS-20.228
nhr-2Protein NHR-20.228
gsk-3Protein GSK-30.228
zyg-9Protein ZYG-90.227
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ascl1aachaete-scute complex-like 1a (Drosophila)0.990
gdf6agrowth differentiation factor 6a0.989
elavl3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)0.987
pitx3paired-like homeodomain transcription factor 30.985
lhx2bLIM homeobox 2b0.984
ptch2patched 20.983
gli2aGLI-Kruppel family member GLI2a0.982
foxd3forkhead box D30.982
rx3retinal homeobox gene 30.977
shhasonic hedgehog a0.961
fgf3fibroblast growth factor 30.957
ephb4beph receptor B4b0.956
wnt8bwingless-type MMTV integration site family, member 8b0.955
plod3procollagen-lysine, 2-oxoglutarate 5-dioxygenase 30.948
cntn2contactin 20.946
alcamaactivated leukocyte cell adhesion molecule a0.943
stmn2bstathmin-like 2b0.942
spry4sprouty (Drosophila) homolog 40.940
raraaretinoic acid receptor, alpha a0.938
lhx1aLIM homeobox 1a0.937
neurog1neurogenin 10.934
gata2aGATA-binding protein 2a0.927
gli1GLI-Kruppel family member 10.916
fgfr4fibroblast growth factor receptor 40.913
pcdh18bprotocadherin 18b0.910
prdm1aPR domain containing 1a, with ZNF domain0.902
alcambactivated leukocyte cell adhesion molecule b0.893
scn8aasodium channel, voltage-gated, type VIII, alpha a0.892
cxcr4bchemokine (C-X-C motif), receptor 4b0.885
slc17a6bsolute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b0.849
sox19aSRY-box containing gene 19a0.843
exorhextra-ocular rhodopsin0.835
atoh7atonal homolog 70.817
phox2apaired-like homeobox 2a0.809
bocbrother of CDO0.809
olig2oligodendrocyte lineage transcription factor 20.804
pax2apaired box gene 2a0.783
cdh6cadherin 60.779
lamc1laminin, gamma 10.774
flhfloating head0.769
zic3zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)0.762
crabp2acellular retinoic acid binding protein 2, a0.758
dlx2adistal-less homeobox gene 2a0.740
foxi1forkhead box I10.739
tbx1T-box 10.733
nrp2bneuropilin 2b0.703
gcm2glial cells missing homolog 2 (Drosophila)0.692
lama2laminin, alpha 20.690
six3bsine oculis homeobox homolog 3b0.689
gro1groucho 10.687
epha4beph receptor A4b0.684
ndr2nodal-related 20.678
fezf2FEZ family zinc finger 20.672
lamb1alaminin, beta 1a0.666
restRE1-silencing transcription factor0.656
epha4aeph receptor A4a0.649
efnb1ephrin B10.648
pax6apaired box gene 6a0.642
notch2notch homolog 20.642
myhz2myosin, heavy polypeptide 2, fast muscle specific0.641
adcyap1badenylate cyclase activating polypeptide 1b0.640
nr2e1nuclear receptor subfamily 2, group E, member 10.639
kbpkif1-binding protein0.623
ttnatitin a0.622
tgfb3transforming growth factor, beta 30.615
her4.2hairy-related 4.20.601
sox1aSRY-box containing gene 1a0.598
hey1hairy/enhancer-of-split related with YRPW motif 10.597
myhz1.1myosin, heavy polypeptide 1.1, skeletal muscle0.595
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.594
eya1eyes absent homolog 10.594
vcanbversican b0.592
wnt10awingless-type MMTV integration site family, member 10a0.583
dpysl3dihydropyrimidinase-like 30.581
wnt1wingless-type MMTV integration site family, member 10.577
tpbgltrophoblast glycoprotein-like0.570
her6hairy-related 60.567
sim1asingle-minded homolog 1a (Drosophila)0.564
gmdsGDP-mannose 4,6-dehydratase0.559
fgf10afibroblast growth factor 10a0.558
stmn2astathmin-like 2a0.555
irx4biroquois homeobox protein 4b0.555
otpborthopedia homolog b0.547
mapk3mitogen-activated protein kinase 30.540
irx1biroquois homeobox protein 1, b0.536
gad2glutamate decarboxylase 20.534
pea3ETS-domain transcription factor pea30.534
sox2SRY-box containing gene 20.529
axin1axin 10.525
itgb1bintegrin, beta 1b0.523
nkx2.2aNK2 transcription factor related 2a0.518
neurodneurogenic differentiation0.513
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
trioCG18214 gene product from transcript CG18214-RA1.000
Sema-1aCG18405 gene product from transcript CG18405-RD1.000
MicalMolecule interacting with CasL1.000
lolalongitudinals lacking1.000
Ptp69DProtein tyrosine phosphatase 69D1.000
Rac1CG2248 gene product from transcript CG2248-RA1.000
shotshort stop1.000
Fas2Fasciclin 20.999
DscamDown syndrome cell adhesion molecule0.999
Sema-2aCG4700 gene product from transcript CG4700-RC0.999
AblAbl tyrosine kinase0.999
unc-5CG8166 gene product from transcript CG8166-RA0.999
CkIIalphaCasein kinase II alpha subunit0.999
TBPHCG10327 gene product from transcript CG10327-RC0.998
plexBplexin B0.998
Trim9CG31721 gene product from transcript CG31721-RB0.998
Ten-mTenascin major0.997
CaMKIICalcium/calmodulin-dependent protein kinase II0.997
AcslAcyl-CoA synthetase long-chain0.995
eyaeyes absent0.994
CapsCalcium activated protein for secretion0.992
dallydivision abnormally delayed0.991
G-oalpha47AG protein oalpha 47A0.990
HGTXCG13475 gene product from transcript CG13475-RB0.990
gogogolden goal0.990
E(spl)Enhancer of split0.989
Rho1CG8416 gene product from transcript CG8416-RB0.989
emsempty spiracles0.985
elavembryonic lethal abnormal vision0.985
eIF-4EEukaryotic initiation factor 4E0.985
Atg1Autophagy-specific gene 10.983
CSN5COP9 complex homolog subunit 50.982
EgfrEpidermal growth factor receptor0.981
mewmultiple edematous wings0.980
Fas3Fasciclin 30.979
Wnt5Wnt oncogene analog 50.979
MadMothers against dpp0.979
htshu li tai shao0.979
pod1CG4532 gene product from transcript CG4532-RF0.978
rapretina aberrant in pattern0.978
unc-104CG8566 gene product from transcript CG8566-RB0.975
Syx1ASyntaxin 1A0.972
aopanterior open0.971
Gyc76CGuanylyl cyclase at 76C0.969
emcextra macrochaetae0.966
ctpcut up0.965
CG12424CG12424 gene product from transcript CG12424-RC0.962
DadDaughters against dpp0.961
CycACyclin A0.960
robo3CG5423 gene product from transcript CG5423-RA0.957
stanstarry night0.957
Ca-alpha1DCa[2+]-channel protein alpha[[1]] subunit D0.954
ewgerect wing0.952
Cdc42CG12530 gene product from transcript CG12530-RA0.947
Su(H)Suppressor of Hairless0.947
eIF-4aEukaryotic initiation factor 4a0.944
WnkCG7177 gene product from transcript CG7177-RA0.943
alpha-Specalpha Spectrin0.943
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
FYNFYN oncogene related to SRC, FGR, YES0.978
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.938
EGFRepidermal growth factor receptor0.910
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.904
ATXN1ataxin 10.895
FN1fibronectin 10.786
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.774
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.761
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.700
QKIquaking homolog, KH domain RNA binding (mouse)0.697
FLNAfilamin A, alpha0.662
MAPTmicrotubule-associated protein tau0.620
SMAD2SMAD family member 20.596
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.579
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.536
FGFR1fibroblast growth factor receptor 10.535
PLCG1phospholipase C, gamma 10.526
IGF1Rinsulin-like growth factor 1 receptor0.525
JUNjun proto-oncogene0.515
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.439
NCOR1nuclear receptor corepressor 10.363
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.357
GRB2growth factor receptor-bound protein 20.304
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.296
GSK3Bglycogen synthase kinase 3 beta0.279
APPamyloid beta (A4) precursor protein0.269
ATN1atrophin 10.254
MAPK8mitogen-activated protein kinase 80.252
CREBBPCREB binding protein0.251
SMAD3SMAD family member 30.235
RHOAras homolog gene family, member A0.215
FMR1fragile X mental retardation 10.196
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.192
NTRK3neurotrophic tyrosine kinase, receptor, type 30.180
RASA1RAS p21 protein activator (GTPase activating protein) 10.180
RUNX1runt-related transcription factor 10.179
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.173
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.167
JAG1jagged 10.165
BMI1BMI1 polycomb ring finger oncogene0.162
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.159
KIF5Bkinesin family member 5B0.152
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.152
TAL1T-cell acute lymphocytic leukemia 10.143
PRKCZprotein kinase C, zeta0.139
SMURF2SMAD specific E3 ubiquitin protein ligase 20.135
NTNG1netrin G10.133
MPRIPmyosin phosphatase Rho interacting protein0.129
GRB10growth factor receptor-bound protein 100.127
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.125
HSPA1Bheat shock 70kDa protein 1B0.124
ARHGAP1Rho GTPase activating protein 10.121
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.120
LCKlymphocyte-specific protein tyrosine kinase0.119
SHC1SHC (Src homology 2 domain containing) transforming protein 10.117
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.114
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.111
NCKAP1NCK-associated protein 10.111
CBX8chromobox homolog 80.111
WIPF1WAS/WASL interacting protein family, member 10.106
HNRNPKheterogeneous nuclear ribonucleoprotein K0.104
MAP2K4mitogen-activated protein kinase kinase 40.104
ATF2activating transcription factor 20.103
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.101
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.100
NCAM1neural cell adhesion molecule 10.100
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.100
ITGB4integrin, beta 40.097
FGF1fibroblast growth factor 1 (acidic)0.097
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.097
NCK1NCK adaptor protein 10.095
DLG4discs, large homolog 4 (Drosophila)0.092
PFN1profilin 10.092
PTPN1protein tyrosine phosphatase, non-receptor type 10.092
SOX11SRY (sex determining region Y)-box 110.091
OCRLoculocerebrorenal syndrome of Lowe0.090
TUBB2Atubulin, beta 2A0.090
HSPG2heparan sulfate proteoglycan 20.089
NOTCH1notch 10.089
MAPK1mitogen-activated protein kinase 10.088
NEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like0.087
RANBP9RAN binding protein 90.087
TCF12transcription factor 120.086
PCGF2polycomb group ring finger 20.085
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.083
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)0.082
HDAC1histone deacetylase 10.082
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.081
DTNAdystrobrevin, alpha0.078
VEGFAvascular endothelial growth factor A0.078
FLNBfilamin B, beta0.077
NR4A3nuclear receptor subfamily 4, group A, member 30.076
CSNK2A1casein kinase 2, alpha 1 polypeptide0.076
BAIAP2BAI1-associated protein 20.075
LRRK2leucine-rich repeat kinase 20.073
CAB39calcium binding protein 390.072
RING1ring finger protein 10.072
FNBP1Lformin binding protein 1-like0.072
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Gria2glutamate receptor, ionotropic, AMPA 20.609
Nr4a3nuclear receptor subfamily 4, group A, member 30.608
Nfibnuclear factor I/B0.481
Itgb1integrin, beta 10.480
Map2microtubule-associated protein 20.476
Grip1glutamate receptor interacting protein 10.465
Nrxn1neurexin 10.434
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.430
Ptproprotein tyrosine phosphatase, receptor type, O0.372
Neflneurofilament, light polypeptide0.356
Adrb1adrenergic, beta-1-, receptor0.334
Lin7blin-7 homolog b (C. elegans)0.297
Smad7SMAD family member 70.291
Sstr1somatostatin receptor 10.282
Dlg4discs, large homolog 4 (Drosophila)0.281
Cadm1cell adhesion molecule 10.277
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.274
JunJun oncogene0.273
Fgfr1Fibroblast growth factor receptor 10.269
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.263
Anxa4annexin A40.258
Ptpn12protein tyrosine phosphatase, non-receptor type 120.251
Dact3dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)0.246
Capza2capping protein (actin filament) muscle Z-line, alpha 20.245
Nrcamneuronal cell adhesion molecule0.245
Syt4synaptotagmin IV0.238
Kcnb1potassium voltage gated channel, Shab-related subfamily, member 10.233
Ptprsprotein tyrosine phosphatase, receptor type, S0.231
Ctnnd2catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)0.230
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.227
Robo1roundabout homolog 1 (Drosophila)0.224
Cyth3cytohesin 30.218
Gdf11growth differentiation factor 110.209
Brunol4bruno-like 4, RNA binding protein (Drosophila)0.208
Apba2amyloid beta (A4) precursor protein-binding, family A, member 20.206
Gabrb1gamma-aminobutyric acid (GABA) A receptor, beta 10.205
Nr4a2nuclear receptor subfamily 4, group A, member 20.204
L1camL1 cell adhesion molecule0.204
Actbactin, beta0.204
Sirpasignal-regulatory protein alpha0.202
Pip4k2bphosphatidylinositol-5-phosphate 4-kinase, type II, beta0.198
Brunol5bruno-like 5, RNA binding protein (Drosophila)0.197
Sdc3syndecan 30.196
Eef2eukaryotic translation elongation factor 20.190
Nxph3neurexophilin 30.185
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.183
Hspb1heat shock protein 10.182
Fgfr2fibroblast growth factor receptor 20.180
Ednrbendothelin receptor type B0.177
Map1amicrotubule-associated protein 1A0.176
Btg2BTG family, member 20.175
Lphn3latrophilin 30.172
Egr1early growth response 10.172
Slc12a1solute carrier family 12 (sodium/potassium/chloride transporters), member 10.172
Elavl4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)0.171
Inainternexin neuronal intermediate filament protein, alpha0.166
Slit3slit homolog 3 (Drosophila)0.162
Lppr3lipid phosphate phosphatase-related protein type 30.161
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.160
Dchs1dachsous 1 (Drosophila)0.160
Nefmneurofilament, medium polypeptide0.158
Nedd4neural precursor cell expressed, developmentally down-regulated 40.158
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.155
Egr2early growth response 20.154
Stx1bsyntaxin 1B0.151
Ptpn18protein tyrosine phosphatase, non-receptor type 180.150
Adam17ADAM metallopeptidase domain 170.149
Gabra1gamma-aminobutyric acid (GABA) A receptor, alpha 10.149
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.146
Shank1SH3 and multiple ankyrin repeat domains 10.146
Sbk1SH3-binding domain kinase 10.146
Metmet proto-oncogene0.146
Dlgap1discs, large (Drosophila) homolog-associated protein 10.145
Gata3GATA binding protein 30.145
Syt11synaptotagmin XI0.144
Scn3asodium channel, voltage-gated, type III, alpha0.144
Mmp13matrix metallopeptidase 130.142
Cd44Cd44 molecule0.140
Sp4Sp4 transcription factor0.139
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.138
Taf10TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor0.138
Gria4glutamate receptor, ionotrophic, AMPA 40.136
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.133
Sstr2somatostatin receptor 20.133
Dnajc6DnaJ (Hsp40) homolog, subfamily C, member 60.131
Cltcclathrin, heavy chain (Hc)0.129
Nfianuclear factor I/A0.129
Grm5glutamate receptor, metabotropic 50.128
Tmod2tropomodulin 20.128
SvopSV2 related protein0.128
Map6microtubule-associated protein 60.127
Gabrg2gamma-aminobutyric acid (GABA) A receptor, gamma 20.127
Kcnh1potassium voltage-gated channel, subfamily H (eag-related), member 10.125
Pdgfbplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.125
Col9a1collagen, type IX, alpha 10.123
Rnf165ring finger protein 1650.123
Gabra5gamma-aminobutyric acid (GABA) A receptor, alpha 50.122
Acvr1activin A receptor, type I0.122
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism