The network for 'excretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms


The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

NameDescriptionProbabilityFunc Analog Organism
unc-9Protein UNC-90.124
unc-38Protein UNC-380.109
unc-41Protein UNC-410.108
unc-7Protein UNC-70.095
zag-1Protein ZAG-10.081
nlg-1Protein NLG-10.080
ser-2Protein SER-20.064
mec-2Protein MEC-20.063
stn-1Protein STN-10.061
unc-29Protein UNC-290.060
eps-8Protein EPS-80.055
math-4Protein MATH-40.054
gtl-1Protein GTL-10.053
F28E10.1Protein F28E10.10.052
inx-4Protein INX-40.050
egl-8Protein EGL-80.050
CELE_Y67A10A.9Protein Y67A10A.90.049
unc-42Protein UNC-420.047
glr-5Protein GLR-50.045
lin-11Protein LIN-110.044
twk-18Protein TWK-180.044
rig-6Protein RIG-60.043
C54D10.5Protein C54D10.50.041
H43E16.1Protein H43E16.10.041
C43H6.6Protein C43H6.60.040
cka-2Protein CKA-20.039
CELE_B0513.5Protein B0513.50.039
ant-1.1Protein ANT-1.10.038
CELE_Y105C5A.24Protein Y105C5A.240.038
asp-6Protein ASP-60.036
alx-1Protein ALX-10.035
rgs-6Protein RGS-60.034
cls-1Protein CLS-10.034
flt-1Protein FLT-10.034
max-1Protein MAX-10.033
lev-8Protein LEV-80.033
tph-1Protein TPH-10.033
sto-5Protein STO-50.033
F45E4.3Protein F45E4.30.032
T28B4.1Protein T28B4.10.032
fshr-1Protein FSHR-10.032
elt-6Protein ELT-60.031
dsc-4Protein DSC-40.031
eat-4Protein EAT-40.031
vab-3Protein VAB-30.031
ZC247.2Protein ZC247.20.031
mig-10Protein MIG-100.030
unc-86Protein UNC-860.030
tra-1Protein TRA-10.030
pha-4Protein PHA-40.030
ahr-1Protein AHR-10.030
unc-27Protein UNC-270.029
sdz-28Protein SDZ-280.029
tbh-1Protein TBH-10.029
egl-5Protein EGL-50.029
F16F9.1Protein F16F9.10.028
F14F4.1Protein F14F4.10.028
mec-4Protein MEC-40.027
ctbp-1Protein CTBP-10.027
syg-1Protein SYG-10.027
unc-122Protein UNC-1220.027
acr-16Protein ACR-160.027
mpz-2Protein MPZ-20.027
C48B4.8Protein C48B4.80.027
inx-8Protein INX-80.026
C27H2.2Protein C27H2.20.026
unc-52Protein UNC-520.026
eat-6Protein EAT-60.026
egl-19Protein EGL-190.026
tes-1Protein TES-10.026
madd-4Protein MADD-40.025
CELE_F52C6.2Protein F52C6.20.025
dig-1Protein DIG-10.025
ifd-1Protein IFD-10.025
T21B10.4Protein T21B10.40.025
tbc-16Protein TBC-160.025
rgs-2Protein RGS-20.025
inx-6Protein INX-60.025
R03G8.3Protein R03G8.30.024
ZK287.1Protein ZK287.10.024
dim-1Protein DIM-10.024
mbk-1Protein MBK-10.024
lrp-2Protein LRP-20.023
ldb-1Protein LDB-10.023
CELE_C49C3.4Protein C49C3.40.023
glc-4Protein GLC-40.023
gpa-12Protein GPA-120.022
K11D9.3Protein K11D9.30.022
W08E3.2Protein W08E3.20.022
nhx-1Protein NHX-10.022
F55H12.3Protein F55H12.30.022
CELE_K08E7.6Protein K08E7.60.022
T28D9.4Protein T28D9.40.022
F55H12.4Protein F55H12.40.022
R04E5.2Protein R04E5.20.022
dhp-2Protein DHP-20.021
fat-6Protein FAT-60.021
prmt-3Protein PRMT-30.021
snt-5Protein SNT-50.021
C13C4.5Protein C13C4.50.021
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
unc-13CG2999 gene product from transcript CG2999-RA0.012
highikaru genki0.012
Rya-r44FRyanodine receptor 44F0.012
rolsrolling pebbles0.010
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ADORA2Aadenosine A2a receptor0.833
DRD2dopamine receptor D20.651
PAX3paired box 30.555
UQCRC1ubiquinol-cytochrome c reductase core protein I0.396
JUBjub, ajuba homolog (Xenopus laevis)0.253
CLASP1cytoplasmic linker associated protein 10.245
TUFMTu translation elongation factor, mitochondrial0.241
ABCG8ATP-binding cassette, sub-family G (WHITE), member 80.224
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.210
ABCG5ATP-binding cassette, sub-family G (WHITE), member 50.165
FADS2fatty acid desaturase 20.156
SNAI1snail homolog 1 (Drosophila)0.146
SEC24DSEC24 family, member D (S. cerevisiae)0.098
SEC24ASEC24 family, member A (S. cerevisiae)0.088
QARSglutaminyl-tRNA synthetase0.085
FYNFYN oncogene related to SRC, FGR, YES0.077
TRPC4transient receptor potential cation channel, subfamily C, member 40.074
PHB2prohibitin 20.068
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.068
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.063
CLTCclathrin, heavy chain (Hc)0.058
SOX10SRY (sex determining region Y)-box 100.048
MYO6myosin VI0.045
DHCR77-dehydrocholesterol reductase0.044
ARHGEF40Rho guanine nucleotide exchange factor (GEF) 400.042
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.042
STK38Lserine/threonine kinase 38 like0.042
SLC25A5solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 50.037
NDUFS7NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)0.032
ADORA1adenosine A1 receptor0.032
SLC25A3solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 30.029
OXA1Loxidase (cytochrome c) assembly 1-like0.029
FN1fibronectin 10.028
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.028
NDUFS8NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)0.027
HADHAhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit0.027
SNAP25synaptosomal-associated protein, 25kDa0.027
NDUFS2NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)0.025
IDH3Bisocitrate dehydrogenase 3 (NAD+) beta0.025
NECAB2N-terminal EF-hand calcium binding protein 20.023
SDHAsuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.023
MDH2malate dehydrogenase 2, NAD (mitochondrial)0.022
PDIA3protein disulfide isomerase family A, member 30.019
KCNJ5potassium inwardly-rectifying channel, subfamily J, member 50.019
TRAP1TNF receptor-associated protein 10.019
ADAM11ADAM metallopeptidase domain 110.018
NAMPTnicotinamide phosphoribosyltransferase0.018
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.017
CLTCL1clathrin, heavy chain-like 10.017
LHX3LIM homeobox 30.015
CARHSP1calcium regulated heat stable protein 1, 24kDa0.015
SOS1son of sevenless homolog 1 (Drosophila)0.015
ITGB5integrin, beta 50.015
LATS1LATS, large tumor suppressor, homolog 1 (Drosophila)0.014
YAP1Yes-associated protein 10.014
EIF3CLeukaryotic translation initiation factor 3, subunit C-like0.013
EIF3Geukaryotic translation initiation factor 3, subunit G0.012
C21orf33chromosome 21 open reading frame 330.012
MOBKL1AMOB1, Mps One Binder kinase activator-like 1A (yeast)0.012
FAM190Bfamily with sequence similarity 190, member B0.012
AP2A1adaptor-related protein complex 2, alpha 1 subunit0.012
ANKRD28ankyrin repeat domain 280.012
PCCBpropionyl CoA carboxylase, beta polypeptide0.012
ECH1enoyl CoA hydratase 1, peroxisomal0.011
APEX1APEX nuclease (multifunctional DNA repair enzyme) 10.011
ARF6ADP-ribosylation factor 60.010
EIF3Keukaryotic translation initiation factor 3, subunit K0.010
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.010
PTPRNprotein tyrosine phosphatase, receptor type, N0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Slc34a1solute carrier family 34 (sodium phosphate), member 10.876
Ren1renin 1 structural0.790
Chrnb4cholinergic receptor, nicotinic, beta polypeptide 40.727
Cdh23cadherin 23 (otocadherin)0.682
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.527
Sox10SRY-box containing gene 100.502
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.445
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.318
Drd2dopamine receptor D20.311
Klc1kinesin light chain 10.283
Thrbthyroid hormone receptor beta0.260
Chrnb2cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)0.254
Slc12a1solute carrier family 12, member 10.228
Emx1empty spiracles homolog 1 (Drosophila)0.181
Wnk4WNK lysine deficient protein kinase 40.179
Kcne1potassium voltage-gated channel, Isk-related subfamily, member 10.155
Agtr1aangiotensin II receptor, type 1a0.155
Nos1nitric oxide synthase 1, neuronal0.148
Grid1glutamate receptor, ionotropic, delta 10.147
Srrm4serine/arginine repetitive matrix 40.142
Slc26a4solute carrier family 26, member 40.139
Otx2orthodenticle homolog 2 (Drosophila)0.138
Ryr1ryanodine receptor 1, skeletal muscle0.135
Chrna3cholinergic receptor, nicotinic, alpha polypeptide 30.126
Htr75-hydroxytryptamine (serotonin) receptor 70.125
Stx1asyntaxin 1A (brain)0.118
Wnt6wingless-related MMTV integration site 60.111
S1pr2sphingosine-1-phosphate receptor 20.108
Syt7synaptotagmin VII0.089
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.089
Rims2regulating synaptic membrane exocytosis 20.088
Cldn16claudin 160.082
Barx2BarH-like homeobox 20.075
Slc1a2solute carrier family 1 (glial high affinity glutamate transporter), member 20.075
Plcg1phospholipase C, gamma 10.074
Chrna9cholinergic receptor, nicotinic, alpha polypeptide 90.073
Mapk8mitogen-activated protein kinase 80.072
Hoxb7homeobox B70.071
Abcg5ATP-binding cassette, sub-family G (WHITE), member 50.070
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.068
Leprleptin receptor0.068
Gpr37G protein-coupled receptor 370.063
Pgrprogesterone receptor0.062
Cabp2calcium binding protein 20.060
Sema5bsema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B0.059
Hmx1H6 homeobox 10.059
Ascl1achaete-scute complex homolog 1 (Drosophila)0.059
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.058
Tbx3T-box 30.057
Edn1endothelin 10.057
Emid2EMI domain containing 20.056
Apoa1apolipoprotein A-I0.055
Fbxl20F-box and leucine-rich repeat protein 200.054
Cacnb2calcium channel, voltage-dependent, beta 2 subunit0.052
Mas1MAS1 oncogene0.051
Slc5a2solute carrier family 5 (sodium/glucose cotransporter), member 20.050
Cldn2claudin 20.050
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.050
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.049
Atoh7atonal homolog 7 (Drosophila)0.049
Prox1prospero-related homeobox 10.049
Kcnj11potassium inwardly rectifying channel, subfamily J, member 110.047
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.047
Celcarboxyl ester lipase0.047
Wnt2bwingless related MMTV integration site 2b0.047
Six6sine oculis-related homeobox 6 homolog (Drosophila)0.046
Adra2badrenergic receptor, alpha 2b0.046
Hnf4ahepatic nuclear factor 4, alpha0.046
Scn8asodium channel, voltage-gated, type VIII, alpha0.045
Itpr2inositol 1,4,5-triphosphate receptor 20.043
Tcfap2atranscription factor AP-2, alpha0.043
Dlx4distal-less homeobox 40.042
Hand1heart and neural crest derivatives expressed transcript 10.040
Kcnb1potassium voltage gated channel, Shab-related subfamily, member 10.038
Lmx1aLIM homeobox transcription factor 1 alpha0.038
Mybpc3myosin binding protein C, cardiac0.037
Fgf6fibroblast growth factor 60.037
Gad2glutamic acid decarboxylase 20.036
Adra1aadrenergic receptor, alpha 1a0.036
Hsd3b4hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 40.036
Kif5ckinesin family member 5C0.036
Cacna1bcalcium channel, voltage-dependent, N type, alpha 1B subunit0.036
Rab25RAB25, member RAS oncogene family0.034
Rims1regulating synaptic membrane exocytosis 10.034
Igfbp1insulin-like growth factor binding protein 10.034
Slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.034
Igf1insulin-like growth factor 10.034
Lcn8lipocalin 80.033
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.033
BsndBartter syndrome, infantile, with sensorineural deafness (Barttin)0.032
Myo6myosin VI0.032
Gpr27G protein-coupled receptor 270.032
Cux2cut-like homeobox 20.032
Sorcs1VPS10 domain receptor protein SORCS 10.032
Chrna10cholinergic receptor, nicotinic, alpha polypeptide 100.032
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Csf1colony stimulating factor 1 (macrophage)0.178
Gja6gap junction protein, alpha 60.163
Adora2aadenosine A2a receptor0.147
Slco2b1solute carrier organic anion transporter family, member 2b10.134
Foxd3forkhead box D30.121
Lim2lens intrinsic membrane protein 20.116
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.111
Slc18a3solute carrier family 18 (vesicular acetylcholine), member 30.111
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.105
Hrh3histamine receptor H30.105
P2rx3purinergic receptor P2X, ligand-gated ion channel, 30.103
Capn9calpain 90.091
Olr1641olfactory receptor 16410.085
C8bcomplement component 8, beta polypeptide0.082
RGD1310262hypothetical LOC3046500.077
Grm8glutamate receptor, metabotropic 80.074
Gata4GATA binding protein 40.072
Magmyelin-associated glycoprotein0.067
Impg2interphotoreceptor matrix proteoglycan 20.066
Egr4early growth response 40.065
Prap1proline-rich acidic protein 10.065
Syt4synaptotagmin IV0.063
Myl7myosin, light chain 7, regulatory0.060
Grpgastrin releasing peptide0.060
Cyp21a1cytochrome P450, family 21, subfamily a, polypeptide 10.057
Pnma1paraneoplastic antigen MA10.056
Zp1zona pellucida glycoprotein 1 (sperm receptor)0.055
Neurod2neurogenic differentiation 20.054
Serpina11serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 110.053
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.053
Fbp1fructose-1,6-bisphosphatase 10.052
Aardalanine and arginine rich domain containing protein0.052
Sycp1synaptonemal complex protein 10.052
Cacng5calcium channel, voltage-dependent, gamma subunit 50.052
Agxt2alanine-glyoxylate aminotransferase 20.051
Htr3a5-hydroxytryptamine (serotonin) receptor 3a0.050
Kcnj5potassium inwardly-rectifying channel, subfamily J, member 50.050
Foxe1forkhead box E1 (thyroid transcription factor 2)0.050
Slc13a2solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 20.049
Oprm1opioid receptor, mu 10.048
Atp2b3ATPase, Ca++ transporting, plasma membrane 30.046
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.046
Sstr2somatostatin receptor 20.046
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.045
Mmp10matrix metallopeptidase 100.043
Pax6paired box 60.042
Grm6glutamate receptor, metabotropic 60.040
Kcnb2potassium voltage gated channel, Shab-related subfamily, member 20.040
Pzppregnancy-zone protein0.040
Slc28a1solute carrier family 28 (sodium-coupled nucleoside transporter), member 10.040
Prss1protease, serine, 1 (trypsin 1)0.038
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.038
Pspparotid secretory protein0.037
Chrna3cholinergic receptor, nicotinic, alpha 30.037
Chrna2cholinergic receptor, nicotinic, alpha 2 (neuronal)0.037
Pemtphosphatidylethanolamine N-methyltransferase0.036
Dlgap1discs, large (Drosophila) homolog-associated protein 10.036
Ptger1prostaglandin E receptor 1 (subtype EP1)0.035
Ageradvanced glycosylation end product-specific receptor0.035
Olr1278olfactory receptor 12780.035
Mbl1mannose-binding lectin (protein A) 10.034
Neurog3neurogenin 30.034
C9complement component 90.034
Pklrpyruvate kinase, liver and RBC0.033
Aqp5aquaporin 50.033
Chrna4cholinergic receptor, nicotinic, alpha 40.032
Gpha2glycoprotein hormone alpha 20.032
Erc1ELKS/RAB6-interacting/CAST family member 10.032
Nr4a3nuclear receptor subfamily 4, group A, member 30.032
Grin2cglutamate receptor, ionotropic, N-methyl D-aspartate 2C0.032
Procprotein C0.032
Glra1glycine receptor, alpha 10.032
Gng7guanine nucleotide binding protein (G protein), gamma 70.031
Kcnmb1potassium large conductance calcium-activated channel, subfamily M, beta member 10.031
Tshbthyroid stimulating hormone, beta0.031
Calcacalcitonin-related polypeptide alpha0.031
Shox2short stature homeobox 20.031
Phox2apaired-like homeobox 2a0.031
Calcrcalcitonin receptor0.031
FevFEV (ETS oncogene family)0.031
Apoa5apolipoprotein A-V0.030
Pcdhb12protocadherin beta 120.030
Cntn3contactin 3 (plasmacytoma associated)0.030
Smgbneonatal submandibular gland protein B0.030
Teddm1transmembrane epididymal protein 10.030
Avparginine vasopressin0.030
Ccbp2chemokine binding protein 20.030
Sorcs3sortilin-related VPS10 domain containing receptor 30.030
Olr1361olfactory receptor 13610.030
Foxa1forkhead box A10.029
UncxUNC homeobox0.029
Hsd3b5hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 50.029
Dlgap2discs, large (Drosophila) homolog-associated protein 20.029
Drd2dopamine receptor D20.029
Adra1aadrenergic, alpha-1A-, receptor0.029
Fgf2fibroblast growth factor 20.028
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism