The network for 'regulation of lamellipodium organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of lamellipodium organization

Any process that modulates the frequency, rate or extent of lamellipodium organization.

NameDescriptionProbabilityFunc Analog Organism
cdc-42Protein CDC-420.626
vps-32.1Protein VPS-32.10.379
cap-1Protein CAP-10.275
rab-1Protein RAB-10.145
gsp-1Protein GSP-10.143
arx-1Protein ARX-10.141
goa-1Protein GOA-10.122
F38A5.2Protein F38A5.20.100
pmp-3Protein PMP-30.081
vpr-1Protein VPR-10.078
tag-335Protein TAG-3350.075
atf-7Protein ATF-70.070
sem-5Protein SEM-50.055
C13F10.4Protein C13F10.40.055
mig-2Protein MIG-20.050
fce-1Protein FCE-10.046
scpl-2Protein SCPL-20.043
unc-41Protein UNC-410.036
plc-4Protein PLC-40.034
unc-60Protein UNC-600.033
unc-68Protein UNC-680.031
D2013.6Protein D2013.60.031
xbx-6Protein XBX-60.030
hut-1Protein HUT-10.030
CELE_Y47G6A.18Protein Y47G6A.180.030
T19A6.1Protein T19A6.10.029
F22D3.2Protein F22D3.20.029
unc-45Protein UNC-450.029
rab-5Protein RAB-50.028
pph-4.1Protein PPH-4.10.027
CELE_B0238.10Protein B0238.100.027
kin-3Protein KIN-30.026
unc-96Protein UNC-960.024
C18E9.2Protein C18E9.20.023
hmr-1Protein HMR-10.022
T21B6.3Protein T21B6.30.021
lir-1Protein LIR-10.021
CELE_Y116A8C.26Protein Y116A8C.260.020
tat-5Protein TAT-50.018
hmg-1.2Protein HMG-1.20.017
CELE_T26E3.4Protein T26E3.40.017
csk-1Protein CSK-10.017
syg-1Protein SYG-10.016
unc-73Protein UNC-730.016
C33H5.18Protein C33H5.180.015
yif-1Protein YIF-10.015
C52B9.4Protein C52B9.40.015
mtm-1Protein MTM-10.015
pat-3Protein PAT-30.015
paqr-2Protein PAQR-20.015
T25G3.4Protein T25G3.40.015
ubc-3Protein UBC-30.014
abu-12Protein ABU-120.014
F55A11.1Protein F55A11.10.013
T23F11.1Protein T23F11.10.013
itsn-1Protein ITSN-10.013
unc-108Protein UNC-1080.013
K07H8.3Protein K07H8.30.013
R08E3.3Protein R08E3.30.013
dhs-6Protein DHS-60.012
K03B8.6Protein K03B8.60.012
unc-1Protein UNC-10.012
riok-1Protein RIOK-10.012
vps-36Protein VPS-360.012
rig-4Protein RIG-40.012
ced-10Protein CED-100.012
vti-1Protein VTI-10.011
ent-2Protein ENT-20.011
rsy-1Protein RSY-10.011
ifp-1Protein IFP-10.011
unc-94Protein UNC-940.011
CELE_F25E5.1Protein F25E5.10.011
unc-50Protein UNC-500.011
cam-1Protein CAM-10.011
let-60Protein LET-600.011
hmgr-1Protein HMGR-10.011
F45G2.4Protein F45G2.40.011
rga-2Protein RGA-20.010
T03G6.1Protein T03G6.10.010
CELE_Y110A2AR.3Protein Y110A2AR.30.010
B0416.5Protein B0416.50.010
CELE_C25A1.5Protein C25A1.50.010
tbc-15Protein TBC-150.010
vps-11Protein VPS-110.010
F38E9.5Protein F38E9.50.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Rho1CG8416 gene product from transcript CG8416-RB0.860
chicchickadee0.722
EphrinCG1862 gene product from transcript CG1862-RA0.654
bazbazooka0.645
par-1CG8201 gene product from transcript CG8201-RA0.540
Rac1CG2248 gene product from transcript CG2248-RA0.481
Rbsn-5Rabenosyn-50.445
Sop2Suppressor of profilin 20.390
roboroundabout0.372
MtlMig-2-like0.281
AIFApoptosis inducing factor0.258
DlicDynein light intermediate chain0.243
Arf51FADP ribosylation factor 51F0.189
msnmisshapen0.169
Cip4CG15015 gene product from transcript CG15015-RA0.159
cpbcapping protein beta0.154
rokRho-kinase0.138
AblAbl tyrosine kinase0.137
RalaRas-related protein0.119
p120ctnAdherens junction protein p1200.112
Arp66BActin-related protein 66B0.103
enaenabled0.094
CG11242CG11242 gene product from transcript CG11242-RA0.094
Akt1CG4006 gene product from transcript CG4006-RA0.088
kuzkuzbanian0.085
CragCalmodulin-binding protein related to a Rab3 GDP/GTP exchange protein0.081
ctaconcertina0.080
cpacapping protein alpha0.079
lqfRliquid facets-Related0.079
twftwinfilin0.069
sds22CG5851 gene product from transcript CG5851-RA0.058
Pak3CG14895 gene product from transcript CG14895-RA0.058
S6kRPS6-p70-protein kinase0.057
Flo-2flotillin 20.056
HemHEM-protein0.051
par-6CG5884 gene product from transcript CG5884-RA0.049
ric8aCG15797 gene product from transcript CG15797-RA0.049
latlatheo0.048
CG11791CG11791 gene product from transcript CG11791-RB0.046
sqhspaghetti squash0.045
Rab11Rab-protein 110.042
14-3-3zetaCG17870 gene product from transcript CG17870-RB0.042
Vrp1Verprolin 10.040
Dhc64CDynein heavy chain 64C0.039
uspultraspiracle0.038
Lis-1Lissencephaly-10.038
Rpn6Proteasome p44.5 subunit0.034
LamCLamin C0.032
PakPAK-kinase0.031
scbscab0.030
flrflare0.030
Rab5Rab-protein 50.030
Cad99CCG31009 gene product from transcript CG31009-RB0.029
CkIalphaCasein kinase Ialpha0.029
Arc-p34CG10954 gene product from transcript CG10954-RA0.028
Dap160Dynamin associated protein 1600.026
Rab2Rab-protein 20.026
laceCG4162 gene product from transcript CG4162-RA0.025
taitaiman0.025
BicDBicaudal D0.024
swshort wing0.024
RanBPMRan-binding protein M0.023
mbcmyoblast city0.023
PtenCG5671 gene product from transcript CG5671-RB0.022
LIMK1LIM-kinase10.022
Rab6Rab-protein 60.022
CapsCalcium activated protein for secretion0.022
CrebB-17ACyclic-AMP response element binding protein B at 17A0.021
CG17082CG17082 gene product from transcript CG17082-RD0.021
staistathmin0.020
KhcKinesin heavy chain0.019
Mpp6M-phase phosphoprotein 60.018
fngfringe0.018
cdmcadmus0.018
CalpBCalpain-B0.017
yataCG1973 gene product from transcript CG1973-RA0.017
Mob2CG11711 gene product from transcript CG11711-RC0.017
BaldspotCG3971 gene product from transcript CG3971-RA0.016
kiskismet0.016
Elp3Elongator complex protein 30.015
katanin-60katanin 600.015
notnon-stop0.014
SybSynaptobrevin0.014
snsinged0.013
vps2CG14542 gene product from transcript CG14542-RA0.013
dshdishevelled0.013
CG9650CG9650 gene product from transcript CG9650-RG0.013
r2d2CG7138 gene product from transcript CG7138-RB0.013
gbgenderblind0.013
jagnjagunal0.012
RicRas which interacts with Calmodulin0.012
CG6650CG6650 gene product from transcript CG6650-RA0.012
Act5CActin 5C0.012
RhoGAPp190CG32555 gene product from transcript CG32555-RB0.012
vavCG7893 gene product from transcript CG7893-RB0.012
myoglianinCG1838 gene product from transcript CG1838-RD0.012
jingCG9397 gene product from transcript CG9397-RI0.012
wtswarts0.011
Arc-p20CG5972 gene product from transcript CG5972-RA0.011
heixheixuedian0.011
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.953
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.803
BAIAP2BAI1-associated protein 20.696
ZNF746zinc finger protein 7460.623
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.341
PRKCZprotein kinase C, zeta0.307
ARPC5actin related protein 2/3 complex, subunit 5, 16kDa0.098
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.070
GAS7growth arrest-specific 70.067
EPS8epidermal growth factor receptor pathway substrate 80.058
CAP1CAP, adenylate cyclase-associated protein 1 (yeast)0.058
ARPC1Bactin related protein 2/3 complex, subunit 1B, 41kDa0.057
TWF2twinfilin, actin-binding protein, homolog 2 (Drosophila)0.057
GRB7growth factor receptor-bound protein 70.046
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.043
PFN1profilin 10.039
ATN1atrophin 10.037
LDOC1leucine zipper, down-regulated in cancer 10.034
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.034
NCOA1nuclear receptor coactivator 10.033
PFDN1prefoldin subunit 10.031
ARPC3actin related protein 2/3 complex, subunit 3, 21kDa0.030
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.030
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.029
SORBS3sorbin and SH3 domain containing 30.028
LLGL2lethal giant larvae homolog 2 (Drosophila)0.027
ACTR2ARP2 actin-related protein 2 homolog (yeast)0.027
EFNA1ephrin-A10.026
EFNA5ephrin-A50.025
LLGL1lethal giant larvae homolog 1 (Drosophila)0.024
SPTBN1spectrin, beta, non-erythrocytic 10.023
FZD1frizzled homolog 1 (Drosophila)0.023
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.022
NUMBnumb homolog (Drosophila)0.021
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.021
GIT1G protein-coupled receptor kinase interacting ArfGAP 10.020
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.020
PRKCIprotein kinase C, iota0.020
COTL1coactosin-like 1 (Dictyostelium)0.020
RAC2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.019
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.019
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.017
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.016
RPTORregulatory associated protein of MTOR, complex 10.016
SH3BGRL3SH3 domain binding glutamic acid-rich protein like 30.016
RIPK3receptor-interacting serine-threonine kinase 30.016
CD2APCD2-associated protein0.016
ZNF71zinc finger protein 710.014
GIT2G protein-coupled receptor kinase interacting ArfGAP 20.014
FAT1FAT tumor suppressor homolog 1 (Drosophila)0.014
TPM4tropomyosin 40.013
UBE2R2ubiquitin-conjugating enzyme E2R 20.013
PTOV1prostate tumor overexpressed 10.012
CREBBPCREB binding protein0.012
CAPZBcapping protein (actin filament) muscle Z-line, beta0.012
MYL12Bmyosin, light chain 12B, regulatory0.012
CORO1Acoronin, actin binding protein, 1A0.012
ABI2abl-interactor 20.012
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.011
MEF2Amyocyte enhancer factor 2A0.011
DEF6differentially expressed in FDCP 6 homolog (mouse)0.011
VAV1vav 1 guanine nucleotide exchange factor0.010
ARPC4actin related protein 2/3 complex, subunit 4, 20kDa0.010
NCF2neutrophil cytosolic factor 20.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.087
Vaspvasodilator-stimulated phosphoprotein0.083
Pxnpaxillin0.056
Enahenabled homolog (Drosophila)0.048
Lrrk2leucine-rich repeat kinase 20.048
Tpm4tropomyosin 40.030
Msnmoesin0.025
Mef2dmyocyte enhancer factor 2D0.025
EvlEna-vasodilator stimulated phosphoprotein0.024
Coro1bcoronin, actin binding protein 1B0.022
Cdc42se1CDC42 small effector 10.019
Slit3slit homolog 3 (Drosophila)0.018
Cnn2calponin 20.017
Robo1roundabout homolog 1 (Drosophila)0.017
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.015
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.014
Abi1abl-interactor 10.014
Rac1RAS-related C3 botulinum substrate 10.013
Capzbcapping protein (actin filament) muscle Z-line, beta0.012
Cybacytochrome b-245, alpha polypeptide0.012
Rhoaras homolog gene family, member A0.011
6720456B07RikRIKEN cDNA 6720456B07 gene0.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Hsph1heat shock 105/110 protein 10.190
Hspa8heat shock protein 80.034
Hspd1heat shock protein 1 (chaperonin)0.024
Arpc2actin related protein 2/3 complex, subunit 20.023
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.018
Actbactin, beta0.016
Eif4heukaryotic translation initiation factor 4H0.016
Taglntransgelin0.015
Mapre1microtubule-associated protein, RP/EB family, member 10.014
Acta2smooth muscle alpha-actin0.012
Actg1actin, gamma 10.012
Stip1stress-induced phosphoprotein 10.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism