The network for 'negative regulation of lymphocyte differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of lymphocyte differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation.

NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.420
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.083
STAT6signal transducer and activator of transcription 6, interleukin-4 induced0.059
CD80CD80 molecule0.049
BMPR1Abone morphogenetic protein receptor, type IA0.039
HLA-DPA1major histocompatibility complex, class II, DP alpha 10.013
GHRgrowth hormone receptor0.012
CXCR4chemokine (C-X-C motif) receptor 40.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gli3GLI-Kruppel family member GLI30.979
Stat3signal transducer and activator of transcription 30.951
Fgfr2fibroblast growth factor receptor 20.942
Bcl3B-cell leukemia/lymphoma 30.835
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.817
Zeb1zinc finger E-box binding homeobox 10.780
Ptch1patched homolog 10.740
Id3inhibitor of DNA binding 30.735
Cdkn1bcyclin-dependent kinase inhibitor 1B0.735
Jak2Janus kinase 20.696
Gli2GLI-Kruppel family member GLI20.679
Il6stinterleukin 6 signal transducer0.651
Rb1retinoblastoma 10.537
Nf1neurofibromatosis 10.525
Runx2runt related transcription factor 20.505
Id1inhibitor of DNA binding 10.504
Kdrkinase insert domain protein receptor0.484
Twist2twist homolog 2 (Drosophila)0.450
Foxc1forkhead box C10.423
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.406
Ptenphosphatase and tensin homolog0.385
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.382
Sox9SRY-box containing gene 90.381
Rc3h1RING CCCH (C3H) domains 10.323
Fgf10fibroblast growth factor 100.303
Fgfr3fibroblast growth factor receptor 30.303
Socs1suppressor of cytokine signaling 10.300
Fgf9fibroblast growth factor 90.255
Sfrp2secreted frizzled-related protein 20.245
Csf1colony stimulating factor 1 (macrophage)0.234
Vangl2vang-like 2 (van gogh, Drosophila)0.219
Stat6signal transducer and activator of transcription 60.209
Socs3suppressor of cytokine signaling 30.205
Sfrp1secreted frizzled-related protein 10.204
Sfpi1SFFV proviral integration 10.182
Ighimmunoglobulin heavy chain complex0.177
Trp63transformation related protein 630.175
Ror2receptor tyrosine kinase-like orphan receptor 20.175
Sox2SRY-box containing gene 20.160
Trp53transformation related protein 530.155
Plcg1phospholipase C, gamma 10.154
Pax3paired box gene 30.151
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.145
Irf8interferon regulatory factor 80.139
Batfbasic leucine zipper transcription factor, ATF-like0.136
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.131
Tgfb1transforming growth factor, beta 10.129
Pthlhparathyroid hormone-like peptide0.124
Col2a1collagen, type II, alpha 10.118
Stat2signal transducer and activator of transcription 20.117
Foxp3forkhead box P30.106
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.105
Meox2mesenchyme homeobox 20.104
Socs5suppressor of cytokine signaling 50.104
Cdkn2ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)0.098
Shhsonic hedgehog0.097
Cishcytokine inducible SH2-containing protein0.094
Msx2homeobox, msh-like 20.093
Chd7chromodomain helicase DNA binding protein 70.092
H2-DMahistocompatibility 2, class II, locus DMa0.089
Pcsk5proprotein convertase subtilisin/kexin type 50.088
Arandrogen receptor0.088
Notonotochord homolog (Xenopus laevis)0.087
Ephb2Eph receptor B20.087
Msh2mutS homolog 2 (E. coli)0.083
Egr2early growth response 20.083
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.081
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.077
Bmp7bone morphogenetic protein 70.075
Il4rainterleukin 4 receptor, alpha0.074
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.072
Mmp9matrix metallopeptidase 90.069
Ptmaprothymosin alpha0.066
Kitlkit ligand0.066
Hoxa5homeobox A50.065
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.063
Csf2rb2colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)0.063
Hhexhematopoietically expressed homeobox0.062
Hes1hairy and enhancer of split 1 (Drosophila)0.061
Ikzf1IKAROS family zinc finger 10.061
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.061
Sprr2ksmall proline-rich protein 2K0.061
Cdh5cadherin 50.060
Wnt5awingless-related MMTV integration site 5A0.059
Stat5asignal transducer and activator of transcription 5A0.059
Ptpn11protein tyrosine phosphatase, non-receptor type 110.059
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.058
Prrx1paired related homeobox 10.057
Flt4FMS-like tyrosine kinase 40.057
Vegfcvascular endothelial growth factor C0.056
Cd40CD40 antigen0.056
Smosmoothened homolog (Drosophila)0.056
Gata3GATA binding protein 30.056
Socs2suppressor of cytokine signaling 20.054
Xpaxeroderma pigmentosum, complementation group A0.054
Dsg4desmoglein 40.053
Alx4aristaless-like homeobox 40.053
Traf6TNF receptor-associated factor 60.053
Icosinducible T-cell co-stimulator0.051
Pax6paired box gene 60.051
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
RT1-Db1RT1 class II, locus Db10.133
RT1-DMaRT1 class II, locus DMa0.048
RT1-DaRT1 class II, locus Da0.036
RT1-BaRT1 class II, locus Ba0.025
RT1-BbRT1 class II, locus Bb0.017
RT1-DMbRT1 class II, locus DMb0.016
Pld4phospholipase D family, member 40.013
C1qccomplement component 1, q subcomponent, C chain0.013
Lrg1leucine-rich alpha-2-glycoprotein 10.013
Cd4Cd4 molecule0.012
Laptm5lysosomal protein transmembrane 50.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism