The network for 'positive regulation of multicellular organismal process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of multicellular organismal process

Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

NameDescriptionProbabilityFunc Analog Organism
hlh-2Protein HLH-20.849
egl-18Protein EGL-180.816
dim-1Protein DIM-10.763
elt-6Protein ELT-60.753
unc-73Protein UNC-730.727
sem-5Protein SEM-50.722
unc-62Protein UNC-620.707
egl-13Protein EGL-130.679
inx-12Protein INX-120.664
hlh-1Protein HLH-10.638
bar-1Protein BAR-10.582
unc-52Protein UNC-520.557
egl-46Protein EGL-460.548
vab-3Protein VAB-30.503
daf-4Protein DAF-40.499
nhr-2Protein NHR-20.498
egl-8Protein EGL-80.496
col-17Protein COL-170.476
cye-1Protein CYE-10.467
smp-1Protein SMP-10.456
plc-1Protein PLC-10.451
eor-2Protein EOR-20.447
mab-5Protein MAB-50.446
lin-36Protein LIN-360.443
col-154Protein COL-1540.440
prp-8Protein PRP-80.435
col-157Protein COL-1570.431
glp-1Protein GLP-10.427
anc-1Protein ANC-10.424
ajm-1Protein AJM-10.423
fln-2Protein FLN-20.422
sma-6Protein SMA-60.422
mes-3Protein MES-30.403
inx-3Protein INX-30.399
sdz-28Protein SDZ-280.395
lrp-1Protein LRP-10.395
ten-1Protein TEN-10.392
mep-1Protein MEP-10.383
dre-1Protein DRE-10.382
syg-1Protein SYG-10.382
nola-3Protein NOLA-30.379
nhr-25Protein NHR-250.375
ndk-1Protein NDK-10.373
fkh-2Protein FKH-20.372
nhr-67Protein NHR-670.361
sur-2Protein SUR-20.341
pha-4Protein PHA-40.341
C14C10.5Protein C14C10.50.340
zyg-8Protein ZYG-80.338
sli-1Protein SLI-10.337
abl-1Protein ABL-10.337
hcp-3Protein HCP-30.335
madf-5Protein MADF-50.334
inx-5Protein INX-50.332
C54E4.2Protein C54E4.20.328
adt-2Protein ADT-20.326
ZK84.1Protein ZK84.10.324
T28F4.1Protein T28F4.10.323
lag-1Protein LAG-10.321
daf-12Protein DAF-120.321
col-92Protein COL-920.319
unc-83Protein UNC-830.318
lir-1Protein LIR-10.317
efn-2Protein EFN-20.316
dpl-1Protein DPL-10.313
ZK484.1Protein ZK484.10.311
inx-8Protein INX-80.311
tag-260Protein TAG-2600.309
vav-1Protein VAV-10.307
unc-86Protein UNC-860.304
rol-8Protein ROL-80.303
skp-1Protein SKP-10.302
peb-1Protein PEB-10.302
pal-1Protein PAL-10.301
col-34Protein COL-340.301
sec-10Protein SEC-100.294
rars-1Protein RARS-10.294
unc-16Protein UNC-160.293
pry-1Protein PRY-10.291
dig-1Protein DIG-10.291
W05F2.3Protein W05F2.30.291
F31F7.1Protein F31F7.10.289
pmk-1Protein PMK-10.289
msp-55Protein MSP-550.289
T08A11.2Protein T08A11.20.288
unc-104Protein UNC-1040.288
daf-5Protein DAF-50.288
inx-13Protein INX-130.287
tba-1Protein TBA-10.286
unc-32Protein UNC-320.285
sma-1Protein SMA-10.283
hpo-32Protein HPO-320.279
T28D9.4Protein T28D9.40.279
hcp-6Protein HCP-60.277
eps-8Protein EPS-80.277
hmg-1.1Protein HMG-1.10.275
plc-3Protein PLC-30.273
pde-4Protein PDE-40.272
deb-1Protein DEB-10.271
mtm-3Protein MTM-30.270
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
pax2apaired box gene 2a0.977
cdh2cadherin 2, neuronal0.850
gli1GLI-Kruppel family member 10.813
fgfr1afibroblast growth factor receptor 1a0.726
shhasonic hedgehog a0.626
alcamaactivated leukocyte cell adhesion molecule a0.589
tal1T-cell acute lymphocytic leukemia 10.539
tbx1T-box 10.467
nrg2aneuregulin 2a0.454
jag2jagged 20.443
bmp2bbone morphogenetic protein 2b0.440
gata3GATA-binding protein 30.405
myod1myogenic differentiation 10.390
pax8paired box gene 80.385
alcambactivated leukocyte cell adhesion molecule b0.383
mapk1mitogen-activated protein kinase 10.352
jag1bjagged 1b0.325
hoxd4ahomeo box D4a0.320
fgf17fibroblast growth factor 170.320
foxi1forkhead box I10.301
gdf6agrowth differentiation factor 6a0.298
dccdeleted in colorectal carcinoma0.293
aldh1a2aldehyde dehydrogenase 1 family, member A20.263
tardbpTAR DNA binding protein0.254
sema3absemaphorin 3ab0.250
plagl2pleiomorphic adenoma gene-like 20.248
twist1atwist1a0.246
foxa2forkhead box A20.241
pea3ETS-domain transcription factor pea30.228
wnt4awingless-type MMTV integration site family, member 4a0.226
efnb2aephrin B2a0.226
zic1zic family member 1 (odd-paired homolog, Drosophila)0.225
notch3notch homolog 30.223
chdchordin0.223
gata2aGATA-binding protein 2a0.214
sox9bSRY-box containing gene 9b0.212
junjun proto-oncogene0.211
lamb1alaminin, beta 1a0.210
lmnalamin A0.202
metmet proto-oncogene (hepatocyte growth factor receptor)0.199
dharmadharma0.193
lama4laminin, alpha 40.192
klf4aKruppel-like transcription factor 4a0.189
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.188
wnt10awingless-type MMTV integration site family, member 10a0.188
ptch2patched 20.184
zbtb4zinc finger and BTB domain containing 40.183
sulf1sulfatase 10.181
wnt11rwingless-type MMTV integration site family, member 11, related0.181
ndr2nodal-related 20.180
hoxa13bhomeo box A13b0.165
plcg1phospholipase C, gamma 10.158
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.154
tbx20T-box 200.148
rag1recombination activating gene 10.147
dag1dystroglycan 10.147
aurkbaurora kinase B0.146
wnt2bbwingless-type MMTV integration site family, member 2Bb0.145
bmp2abone morphogenetic protein 2a0.140
otx1borthodenticle homolog 1b0.138
lypd6LY6/PLAUR domain containing 60.136
amotl2aangiomotin like 2a0.136
adra2badrenergic, alpha-2B-, receptor0.136
isl1islet10.132
nrp1aneuropilin 1a0.131
dnmt4DNA (cytosine-5-)-methyltransferase 40.130
igf1rbinsulin-like growth factor 1b receptor0.130
nppanatriuretic peptide precursor A0.126
ascl1aachaete-scute complex-like 1a (Drosophila)0.125
spns2spinster homolog 2 (Drosophila)0.125
pycardPYD and CARD domain containing0.120
otx5orthodenticle homolog 50.120
fabp7afatty acid binding protein 7, brain, a0.119
mstnbmyostatin b0.118
tbx18T-box 180.117
hoxc6bhomeo box C6b0.117
tll1tolloid-like 10.116
traf4atnf receptor-associated factor 4a0.116
thrbthyroid hormone receptor beta0.115
m17IL-6 subfamily cytokine M170.114
evx1even-skipped homeobox 10.114
runx1runt-related transcription factor 10.114
acvr2bactivin receptor IIb0.113
fgf19fibroblast growth factor 190.113
nkx2.2aNK2 transcription factor related 2a0.112
pdlim4PDZ and LIM domain 40.112
ntn1bnetrin 1b0.112
wt1awilms tumor 1a0.110
fras1Fraser syndrome 10.110
hoxd13ahomeo box D13a0.109
bms1lBMS1-like, ribosome assembly protein (yeast)0.108
sox9aSRY-box containing gene 9a0.107
slit3slit (Drosophila) homolog 30.106
bmp4bone morphogenetic protein 40.106
hsp90a.2heat shock protein 90-alpha 20.106
dlbdeltaB0.102
sall1asal-like 1a (Drosophila)0.101
fezf2FEZ family zinc finger 20.100
twist3twist30.099
col15a1bcollagen, type XV, alpha 1b0.099
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Ras85DRas oncogene at 85D0.988
EcREcdysone receptor0.971
EgfrEpidermal growth factor receptor0.967
Pi3K92ECG4141 gene product from transcript CG4141-RB0.957
tsrtwinstar0.953
wgwingless0.930
phlpole hole0.922
Fmr1CG6203 gene product from transcript CG6203-RC0.909
HLHm7E(spl) region transcript m70.905
Tak1TGF-beta activated kinase 10.896
TBPHCG10327 gene product from transcript CG10327-RC0.870
bskbasket0.869
dshdishevelled0.845
ecdecdysoneless0.838
sggshaggy0.836
babobaboon0.822
abd-Aabdominal A0.802
slmbsupernumerary limbs0.755
eIF-4EEukaryotic initiation factor 4E0.745
shnschnurri0.741
rutrutabaga0.740
unc-13CG2999 gene product from transcript CG2999-RA0.738
MadMothers against dpp0.722
lolalongitudinals lacking0.697
G-oalpha47AG protein oalpha 47A0.695
NrgNeuroglian0.685
cpacapping protein alpha0.680
CG11347CG11347 gene product from transcript CG11347-RE0.678
apapterous0.658
SmoxSmad on X0.657
Stat92ESignal-transducer and activator of transcription protein at 92E0.635
Fas2Fasciclin 20.632
Pk61CProtein kinase 61C0.632
Akt1CG4006 gene product from transcript CG4006-RA0.626
hthhomothorax0.613
rictorrapamycin-insensitive companion of Tor0.610
hhhedgehog0.599
kluklumpfuss0.591
E(spl)Enhancer of split0.590
dallydivision abnormally delayed0.563
nejnejire0.559
CaMKIICalcium/calmodulin-dependent protein kinase II0.550
slp1sloppy paired 10.545
TlToll0.527
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.527
foxoforkhead box, sub-group O0.520
drkdownstream of receptor kinase0.509
RYBPRing and YY1 Binding Protein0.497
HLHmbetaE(spl) region transcript mbeta0.487
AntpAntennapedia0.479
zfh1Zn finger homeodomain 10.476
eyaeyes absent0.468
CycDCyclin D0.464
mbcmyoblast city0.460
InRInsulin-like receptor0.459
SoxNSoxNeuro0.456
CrebB-17ACyclic-AMP response element binding protein B at 17A0.453
mspsmini spindles0.451
hephemipterous0.445
nwknervous wreck0.442
Cyp12a4CG6042 gene product from transcript CG6042-RA0.437
CatCatalase0.433
emcextra macrochaetae0.428
Wnt4Wnt oncogene analog 40.428
stgstring0.425
Dap160Dynamin associated protein 1600.420
ovoCG6824 gene product from transcript CG6824-RE0.419
CG12424CG12424 gene product from transcript CG12424-RC0.412
DabDisabled0.404
PakPAK-kinase0.401
robo3CG5423 gene product from transcript CG5423-RA0.400
knknot0.399
witwishful thinking0.391
Su(H)Suppressor of Hairless0.385
lealeak0.385
gtgiant0.378
grogroucho0.375
atoatonal0.374
rlrolled0.372
Ilp2Insulin-like peptide 20.371
wtswarts0.367
S6kRPS6-p70-protein kinase0.367
bowlbrother of odd with entrails limited0.366
ococelliless0.364
tutlturtle0.361
CkIIalphaCasein kinase II alpha subunit0.360
shotshort stop0.359
Ilp5Insulin-like peptide 50.357
NetBNetrin-B0.357
dppdecapentaplegic0.348
LIMK1LIM-kinase10.348
pbproboscipedia0.344
fz2frizzled 20.343
CycBCyclin B0.341
RhebCG1081 gene product from transcript CG1081-RA0.338
chicoCG5686 gene product from transcript CG5686-RB0.337
ftz-f1ftz transcription factor 10.335
midmidline0.335
poloCG12306 gene product from transcript CG12306-RA0.327
crolcrooked legs0.325
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Icam1intercellular adhesion molecule 10.881
Ccr5chemokine (C-C motif) receptor 50.870
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.847
Cd37CD37 molecule0.837
RT1-BaRT1 class II, locus Ba0.804
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.787
Cd80Cd80 molecule0.787
Mmp12matrix metallopeptidase 120.786
Dlgap1discs, large (Drosophila) homolog-associated protein 10.782
Tgfbr2transforming growth factor, beta receptor II0.735
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.727
Junbjun B proto-oncogene0.715
Itgamintegrin, alpha M0.703
Fgfr2fibroblast growth factor receptor 20.700
Pthparathyroid hormone0.689
Otx1orthodenticle homeobox 10.685
Prrx1paired related homeobox 10.682
Ccl2chemokine (C-C motif) ligand 20.682
Dlgap2discs, large (Drosophila) homolog-associated protein 20.673
Vdrvitamin D (1,25- dihydroxyvitamin D3) receptor0.667
Ucnurocortin0.659
Metmet proto-oncogene0.641
Cxcl10chemokine (C-X-C motif) ligand 100.640
Cd4Cd4 molecule0.639
Pecam1platelet/endothelial cell adhesion molecule 10.638
Slc6a12solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 120.630
Neurog3neurogenin 30.622
Ccr2chemokine (C-C motif) receptor 20.621
Sstr1somatostatin receptor 10.620
Tcf4transcription factor 40.615
Adora2aadenosine A2a receptor0.610
Agtr1aangiotensin II receptor, type 1a0.604
P2ry6pyrimidinergic receptor P2Y, G-protein coupled, 60.603
Gja1gap junction protein, alpha 10.601
Bmp6bone morphogenetic protein 60.596
Hoxa2homeo box A20.595
Hspb1heat shock protein 10.592
Ccl3chemokine (C-C motif) ligand 30.590
Scn9asodium channel, voltage-gated, type IX, alpha0.589
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.589
Trhr2thyrotropin releasing hormone receptor 20.589
Ptafrplatelet-activating factor receptor0.584
Zfp36zinc finger protein 360.578
RGD1564664similar to LOC387763 protein0.578
Atf3activating transcription factor 30.577
Syt4synaptotagmin IV0.562
Syt10synaptotagmin X0.559
Nrxn1neurexin 10.558
Phkg1phosphorylase kinase, gamma 10.556
Oprd1opioid receptor, delta 10.554
Plauplasminogen activator, urokinase0.552
Chrnb3cholinergic receptor, nicotinic, beta 30.548
Sox17SRY (sex determining region Y)-box 170.545
Nos2nitric oxide synthase 2, inducible0.543
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.542
Mc5rmelanocortin 5 receptor0.541
Nek9NIMA (never in mitosis gene a)- related kinase 90.539
Sirpasignal-regulatory protein alpha0.528
Sstr5somatostatin receptor 50.528
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.525
Ahsgalpha-2-HS-glycoprotein0.525
Nefhneurofilament, heavy polypeptide0.524
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.520
Ifitm3interferon induced transmembrane protein 30.519
Prap1proline-rich acidic protein 10.518
Cckarcholecystokinin A receptor0.517
Foxd1forkhead box D10.516
Notch2Notch homolog 2 (Drosophila)0.515
Dbhdopamine beta-hydroxylase (dopamine beta-monooxygenase)0.515
LOC60591calcium-activated potassium channel beta subunit0.514
Adam17ADAM metallopeptidase domain 170.514
Stat3signal transducer and activator of transcription 30.511
Fgf18fibroblast growth factor 180.510
Gja5gap junction protein, alpha 50.507
Oxtroxytocin receptor0.503
Fgf10fibroblast growth factor 100.501
Slc6a11solute carrier family 6 (neurotransmitter transporter, GABA), member 110.500
Calcrlcalcitonin receptor-like0.499
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.498
Errfi1ERBB receptor feedback inhibitor 10.497
Dmddystrophin0.494
Pgcprogastricsin (pepsinogen C)0.487
Nrcamneuronal cell adhesion molecule0.485
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.484
Eef2eukaryotic translation elongation factor 20.483
Ier3immediate early response 30.482
Il1rl1interleukin 1 receptor-like 10.476
Anxa1annexin A10.474
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.473
Cntn2contactin 2 (axonal)0.471
UncxUNC homeobox0.468
Itgb7integrin, beta 70.466
Mifmacrophage migration inhibitory factor0.466
Kcnc2potassium voltage gated channel, Shaw-related subfamily, member 20.465
Reg3gregenerating islet-derived 3 gamma0.464
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.464
Egr2early growth response 20.463
Spt1salivary protein 10.462
Zp1zona pellucida glycoprotein 1 (sperm receptor)0.461
Shc2SHC (Src homology 2 domain containing) transforming protein 20.460
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism