The network for 'autophagy' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

autophagy

The process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.

NameDescriptionProbabilityFunc Analog Organism
wdfy-2Protein WDFY-20.581
rpm-1Protein RPM-10.542
atg-18Protein ATG-180.493
unc-51Protein UNC-510.455
let-60Protein LET-600.443
C36C9.1Protein C36C9.10.347
clec-65Protein CLEC-650.332
R12E2.2Protein R12E2.20.305
pal-1Protein PAL-10.253
bec-1Protein BEC-10.250
pcm-1Protein PCM-10.243
glp-1Protein GLP-10.232
hnd-1Protein HND-10.206
unc-14Protein UNC-140.205
skr-16Protein SKR-160.196
C34D10.2Protein C34D10.20.193
sams-4Protein SAMS-40.188
fat-3Protein FAT-30.170
trap-1Protein TRAP-10.167
atg-4.1Protein ATG-4.10.165
ogt-1Protein OGT-10.164
CELE_F53H1.3Protein F53H1.30.163
lgg-2Protein LGG-20.147
fshr-1Protein FSHR-10.141
F52H2.5Protein F52H2.50.141
aak-2Protein AAK-20.136
atg-13Protein ATG-130.129
F26F12.3Protein F26F12.30.120
mvb-12Protein MVB-120.114
CELE_C17F4.7Protein C17F4.70.114
ain-1Protein AIN-10.113
K12H6.6Protein K12H6.60.104
CELE_Y57E12AL.1Protein Y57E12AL.10.099
T01H3.3Protein T01H3.30.096
T16G1.4Protein T16G1.40.091
nhr-22Protein NHR-220.089
C02F5.7Protein C02F5.70.088
F57F5.1Protein F57F5.10.087
hsb-1Protein HSB-10.087
sma-9Protein SMA-90.086
cpd-1Protein CPD-10.086
Y82E9BR.13Protein Y82E9BR.130.085
F42G2.2Protein F42G2.20.083
T23F11.1Protein T23F11.10.083
sur-2Protein SUR-20.082
rbg-1Protein RBG-10.082
CELE_M01B12.4Protein M01B12.40.081
asah-1Protein ASAH-10.081
rpt-3Protein RPT-30.079
eff-1Protein EFF-10.077
fkh-2Protein FKH-20.077
egl-18Protein EGL-180.074
ZC328.3Protein ZC328.30.073
dnj-25Protein DNJ-250.073
elt-6Protein ELT-60.072
W06B4.2Protein W06B4.20.072
F53F10.2Protein F53F10.20.072
drap-1Protein DRAP-10.070
T10B5.7Protein T10B5.70.070
mek-2Protein MEK-20.069
spp-8Protein SPP-80.067
mif-3Protein MIF-30.067
kle-2Protein KLE-20.065
elt-7Protein ELT-70.065
T03F1.1Protein T03F1.10.064
M02E1.1Protein M02E1.10.063
daf-11Protein DAF-110.062
CELE_C44C10.4Protein C44C10.40.060
cutl-26Protein CUTL-260.060
hpo-31Protein HPO-310.060
unc-108Protein UNC-1080.059
F25G6.8Protein F25G6.80.059
sft-4Protein SFT-40.059
miz-1Protein MIZ-10.058
vps-39Protein VPS-390.057
sand-1Protein SAND-10.056
unc-62Protein UNC-620.056
ztf-2Protein ZTF-20.056
pfd-4Protein PFD-40.055
egl-46Protein EGL-460.055
W07E11.1Protein W07E11.10.053
ten-1Protein TEN-10.053
mis-12Protein MIS-120.053
hgo-1Protein HGO-10.053
dcn-1Protein DCN-10.052
pqn-59Protein PQN-590.052
ceh-44Protein CEH-440.052
fut-3Protein FUT-30.050
egl-27Protein EGL-270.050
Y102A11A.3Protein Y102A11A.30.050
lec-8Protein LEC-80.049
lin-40Protein LIN-400.049
Y51F10.7Protein Y51F10.70.049
fat-2Protein FAT-20.049
ZK858.6Protein ZK858.60.048
lat-1Protein LAT-10.048
ZK686.3Protein ZK686.30.047
vps-18Protein VPS-180.047
lgg-1Protein LGG-10.047
pmk-1Protein PMK-10.047
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.859
ripk2receptor-interacting serine-threonine kinase 20.672
map1lc3bmicrotubule-associated protein 1 light chain 3 beta0.644
igf1rbinsulin-like growth factor 1b receptor0.571
tnrc5trinucleotide repeat containing 50.523
ntlano tail a0.454
cdh1cadherin 1, epithelial0.400
limk2LIM domain kinase 20.369
card9caspase recruitment domain family, member 90.354
mxi1max interacting protein0.349
zgc:92606zgc:926060.303
fmr1fragile X mental retardation 10.286
tax1bp1bTax1 (human T-cell leukemia virus type I) binding protein 1b0.283
trim13tripartite motif-containing 130.280
prkar1aaprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a0.273
rab2aRAB2A, member RAS oncogene family0.258
xbp1X-box binding protein 10.256
vps39vacuolar protein sorting 39 homolog (S. cerevisiae)0.251
crb2acrumbs homolog 2a0.232
faf2Fas associated factor family member 20.228
ctsfcathepsin F0.228
gata3GATA-binding protein 30.218
adipor2adiponectin receptor 20.216
atp6ap2ATPase, H+ transporting, lysosomal accessory protein 20.216
mbnl2muscleblind-like 2 (Drosophila)0.211
ddx6DEAD (Asp-Glu-Ala-Asp) box polypeptide 60.188
brd2abromodomain-containing 2a0.187
npc1Niemann-Pick disease, type C10.186
wnt10awingless-type MMTV integration site family, member 10a0.186
zgc:153148zgc:1531480.184
LOC100003514protein kinase C alpha type-like0.184
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.182
ctsdcathepsin D0.181
pou5f1POU domain, class 5, transcription factor 10.181
zbtb4zinc finger and BTB domain containing 40.180
zgc:101761zgc:1017610.179
gata6GATA-binding protein 60.178
npc2Niemann-Pick disease, type C20.172
foxa3forkhead box A30.171
dlg1discs, large (Drosophila) homolog 10.170
mapk3mitogen-activated protein kinase 30.169
sox9bSRY-box containing gene 9b0.164
bc2putative breast adenocarcinoma marker0.161
usp10ubiquitin specific peptidase 100.160
fcho2FCH domain only 20.159
ube4bubiquitination factor E4B, UFD2 homolog (S. cerevisiae)0.157
fbxo45F-box protein 450.152
nudcnuclear distribution gene C homolog0.151
actn4actinin, alpha 40.149
tmprss4atransmembrane protease, serine 4a0.148
slc30a9solute carrier family 30 (zinc transporter), member 90.146
ap1b1adaptor-related protein complex 1, beta 1 subunit0.144
npntnephronectin0.140
calm3bcalmodulin 3b (phosphorylase kinase, delta)0.139
eif4g2aeukaryotic translation initiation factor 4, gamma 2a0.139
arf2ADP-ribosylation factor 20.138
csadcysteine sulfinic acid decarboxylase0.137
trpm7transient receptor potential cation channel, subfamily M, member 70.135
mapk1mitogen-activated protein kinase 10.133
rab5aaRAB5A, member RAS oncogene family, a0.133
slc39a1solute carrier family 39 (zinc transporter), member 10.132
ppp2r1bprotein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform0.131
glb1galactosidase, beta 10.130
odc1ornithine decarboxylase 10.129
ldb1aLIM-domain binding factor 1a0.128
pfn2lprofilin 2 like0.128
si:ch211-146l10.2si:ch211-146l10.20.126
rogdirogdi homolog (Drosophila)0.126
zgc:56136zgc:561360.126
maffv-maf musculoaponeurotic fibrosarcoma oncogene homolog f (avian)0.125
gabarapaGABA(A) receptor-associated protein a0.124
fzd5frizzled homolog 50.124
hdac4histone deacetylase 40.122
bmp2bbone morphogenetic protein 2b0.122
dusp4dual specificity phosphatase 40.122
rab1aRAB1A, member RAS oncogene family0.120
gpr126G protein-coupled receptor 1260.119
grinaglutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)0.118
sdf4stromal cell derived factor 40.118
slc15a2solute carrier family 15 (H+/peptide transporter), member 20.116
tm9sf2transmembrane 9 superfamily member 20.115
si:dkey-8l13.4si:dkey-8l13.40.115
psen1presenilin 10.115
pabpc1apoly A binding protein, cytoplasmic 1 a0.114
smad2MAD homolog 2 (Drosophila)0.114
epb41l5erythrocyte membrane protein band 4.1 like 50.114
ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.113
atp6v1e1bATPase, H+ transporting, lysosomal, V1 subunit E isoform 1b0.113
ctsl1acathepsin L, 1 a0.111
arf5ADP-ribosylation factor 50.111
plxnb2aplexin b2a0.110
smu1smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)0.110
rhoaaras homolog gene family, member Aa0.110
zgc:112986zgc:1129860.110
ap1g1adaptor-related protein complex 1, gamma 1 subunit0.109
cul2cullin 20.107
ikbkginhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.107
atp6ap1ATPase, H+ transporting, lysosomal accessory protein 10.107
tp53tumor protein p530.107
thoc2THO complex 20.107
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Pi3K92ECG4141 gene product from transcript CG4141-RB0.999
Atg8aAutophagy-specific gene 8a0.997
Atg18Autophagy-specific gene 180.997
Ras85DRas oncogene at 85D0.995
Atg1Autophagy-specific gene 10.989
carcarnation0.988
shnschnurri0.973
giggigas0.961
dmdiminutive0.952
CG11347CG11347 gene product from transcript CG11347-RE0.946
rlrolled0.935
RhebCG1081 gene product from transcript CG1081-RA0.922
Dcr-2Dicer-20.886
PtenCG5671 gene product from transcript CG5671-RB0.877
RagACG11968 gene product from transcript CG11968-RA0.873
aopanterior open0.872
Pi3K59FPhosphotidylinositol 3 kinase 59F0.854
Atg2Autophagy-specific gene 20.831
Atg4Autophagy-specific gene 40.782
bskbasket0.756
MadMothers against dpp0.748
shishibire0.722
p53CG33336 gene product from transcript CG33336-RB0.713
Aut1CG6877 gene product from transcript CG6877-RA0.706
CG1347CG1347 gene product from transcript CG1347-RB0.703
CG32581CG32581 gene product from transcript CG32581-RB0.702
scnyscrawny0.698
pr-set7CG3307 gene product from transcript CG3307-RC0.688
Syx17Syntaxin 170.686
drprdraper0.680
Atg13Autophagy-specific gene 130.677
p38bCG7393 gene product from transcript CG7393-RA0.677
Pink1PTEN-induced putative kinase 10.665
trpmltransient receptor potential mucolipin0.650
bchsblue cheese0.644
gbbglass bottom boat0.640
chicoCG5686 gene product from transcript CG5686-RB0.621
usnpubisnap0.580
Vps16AVacuolar protein sorting 16A0.576
S6kRPS6-p70-protein kinase0.572
Atg6Autophagy-specific gene 60.564
CG10277CG10277 gene product from transcript CG10277-RB0.559
babobaboon0.544
StamSignal transducing adaptor molecule0.543
neurneuralized0.538
Atg9Autophagy-specific gene 90.533
hephemipterous0.521
Rpn2CG11888 gene product from transcript CG11888-RA0.520
ird1immune response deficient 10.508
PP2A-B'CG7913 gene product from transcript CG7913-RK0.507
l(2)gllethal (2) giant larvae0.504
Sox14Sox box protein 140.497
spinspinster0.483
RalaRas-related protein0.470
Stat92ESignal-transducer and activator of transcription protein at 92E0.468
Rab7Rab-protein 70.466
SNF1ASNF1A/AMP-activated protein kinase0.463
CG42863CG42863 gene product from transcript CG42863-RB0.458
RelRelish0.436
Dcp-1Death caspase-10.424
CG6116CG6116 gene product from transcript CG6116-RA0.420
TBPHCG10327 gene product from transcript CG10327-RC0.417
Atg7Autophagy-specific gene 70.405
stysprouty0.394
unkunkempt0.386
srasarah0.383
LLobe0.382
kaykayak0.380
cathDCG1548 gene product from transcript CG1548-RA0.376
nejnejire0.375
InRInsulin-like receptor0.352
CG8709CG8709 gene product from transcript CG8709-RK0.345
ykiyorkie0.338
bowlbrother of odd with entrails limited0.338
LnkCG17367 gene product from transcript CG17367-RC0.333
IceCG7788 gene product from transcript CG7788-RA0.332
tkvthickveins0.321
dppdecapentaplegic0.319
CG11877CG11877 gene product from transcript CG11877-RA0.307
RfabgRetinoid- and fatty acid-binding glycoprotein0.305
B52CG10851 gene product from transcript CG10851-RB0.300
rbruby0.298
loqsloquacious0.291
spasspastin0.285
Pp2B-14DProtein phosphatase 2B at 14D0.279
Vap-33-1CG5014 gene product from transcript CG5014-RB0.279
drkdownstream of receptor kinase0.278
ltlight0.276
cpacapping protein alpha0.273
vps2CG14542 gene product from transcript CG14542-RA0.270
Gienovel GTPase indispensable for equal segregation of chromosomes0.265
emcextra macrochaetae0.261
ninaEneither inactivation nor afterpotential E0.258
fkhfork head0.254
ggarnet0.254
miltmilton0.244
JraJun-related antigen0.234
stepsteppke0.233
locolocomotion defects0.230
CG7967CG7967 gene product from transcript CG7967-RA0.230
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SQSTM1sequestosome 11.000
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.999
MAP1LC3Bmicrotubule-associated protein 1 light chain 3 beta0.999
GABARAPL2GABA(A) receptor-associated protein-like 20.999
GABARAPGABA(A) receptor-associated protein0.997
ATG3ATG3 autophagy related 3 homolog (S. cerevisiae)0.994
AKT1v-akt murine thymoma viral oncogene homolog 10.991
ULK1unc-51-like kinase 1 (C. elegans)0.988
PINK1PTEN induced putative kinase 10.958
S100A6S100 calcium binding protein A60.947
UBCubiquitin C0.944
GABARAPL1GABA(A) receptor-associated protein like 10.941
NBR1neighbor of BRCA1 gene 10.940
TSC2tuberous sclerosis 20.892
BECN1beclin 1, autophagy related0.887
MTORmechanistic target of rapamycin (serine/threonine kinase)0.869
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.868
PTK2PTK2 protein tyrosine kinase 20.868
ATG12ATG12 autophagy related 12 homolog (S. cerevisiae)0.842
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.831
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.825
OPTNoptineurin0.816
GSK3Bglycogen synthase kinase 3 beta0.813
ATG13ATG13 autophagy related 13 homolog (S. cerevisiae)0.791
MDM2Mdm2 p53 binding protein homolog (mouse)0.783
CREBBPCREB binding protein0.714
SMURF2SMAD specific E3 ubiquitin protein ligase 20.680
EGFRepidermal growth factor receptor0.675
FKBP1AFK506 binding protein 1A, 12kDa0.622
UBE2Aubiquitin-conjugating enzyme E2A (RAD6 homolog)0.613
GRB2growth factor receptor-bound protein 20.604
TP53tumor protein p530.590
SIRT1sirtuin 10.585
PRKAB2protein kinase, AMP-activated, beta 2 non-catalytic subunit0.582
RB1CC1RB1-inducible coiled-coil 10.560
ARandrogen receptor0.543
S100BS100 calcium binding protein B0.535
S100A8S100 calcium binding protein A80.514
SMN1survival of motor neuron 1, telomeric0.501
MAP1LC3Amicrotubule-associated protein 1 light chain 3 alpha0.501
PIK3C3phosphoinositide-3-kinase, class 30.496
MAPK8mitogen-activated protein kinase 80.495
PTPN23protein tyrosine phosphatase, non-receptor type 230.494
ANXA2annexin A20.490
FUNDC2FUN14 domain containing 20.484
S100A10S100 calcium binding protein A100.463
S100A9S100 calcium binding protein A90.458
BCL2B-cell CLL/lymphoma 20.454
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.436
ATG5ATG5 autophagy related 5 homolog (S. cerevisiae)0.419
MPDZmultiple PDZ domain protein0.407
SMAD3SMAD family member 30.406
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.380
JUNjun proto-oncogene0.362
MAP2K1mitogen-activated protein kinase kinase 10.350
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha0.339
UBXN6UBX domain protein 60.338
TFRCtransferrin receptor (p90, CD71)0.332
SESN2sestrin 20.330
PPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma0.320
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.311
MAPK1mitogen-activated protein kinase 10.308
IRS2insulin receptor substrate 20.304
STX5syntaxin 50.302
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.291
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.289
BCAR1breast cancer anti-estrogen resistance 10.287
PPP2R1Bprotein phosphatase 2, regulatory subunit A, beta0.284
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 10.281
RAD23ARAD23 homolog A (S. cerevisiae)0.268
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.263
SMAD4SMAD family member 40.263
KIF5Bkinesin family member 5B0.259
OTUB1OTU domain, ubiquitin aldehyde binding 10.259
NLRC4NLR family, CARD domain containing 40.257
TOLLIPtoll interacting protein0.249
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.239
DAPK1death-associated protein kinase 10.237
POLR2Apolymerase (RNA) II (DNA directed) polypeptide A, 220kDa0.233
PPP2R5Aprotein phosphatase 2, regulatory subunit B', alpha0.232
IRAK2interleukin-1 receptor-associated kinase 20.228
FLNAfilamin A, alpha0.225
FKBP4FK506 binding protein 4, 59kDa0.224
MAPK14mitogen-activated protein kinase 140.220
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 10.220
HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)0.218
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.216
TSG101tumor susceptibility gene 1010.216
VTI1Bvesicle transport through interaction with t-SNAREs homolog 1B (yeast)0.216
TRIM63tripartite motif containing 630.210
ATXN3ataxin 30.208
RAB1ARAB1A, member RAS oncogene family0.197
NSFN-ethylmaleimide-sensitive factor0.197
RHEBRas homolog enriched in brain0.194
CDC37cell division cycle 37 homolog (S. cerevisiae)0.192
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.191
SMPD1sphingomyelin phosphodiesterase 1, acid lysosomal0.189
CDKN1Ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.186
RRAGARas-related GTP binding A0.183
MAPK3mitogen-activated protein kinase 30.182
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Sqstm1sequestosome 10.997
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.989
Ptenphosphatase and tensin homolog0.983
Ulk1Unc-51 like kinase 1 (C. elegans)0.977
Psen1presenilin 10.951
Rb1retinoblastoma 10.944
Ptpn11protein tyrosine phosphatase, non-receptor type 110.925
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.911
Ctnnb1catenin (cadherin associated protein), beta 10.902
Atg12autophagy-related 12 (yeast)0.838
Hif1ahypoxia inducible factor 1, alpha subunit0.824
Cyldcylindromatosis (turban tumor syndrome)0.814
Notch2Notch gene homolog 2 (Drosophila)0.788
Casp4caspase 4, apoptosis-related cysteine peptidase0.777
Gbp2guanylate binding protein 20.773
Ppargperoxisome proliferator activated receptor gamma0.680
BrafBraf transforming gene0.677
Stat1signal transducer and activator of transcription 10.659
Vhlvon Hippel-Lindau tumor suppressor0.607
Iigp1interferon inducible GTPase 10.606
Atf2activating transcription factor 20.593
PycardPYD and CARD domain containing0.586
Gbp7guanylate binding protein 70.572
Tsc1tuberous sclerosis 10.565
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.540
Notch1Notch gene homolog 1 (Drosophila)0.531
Prkab1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.528
Igtpinterferon gamma induced GTPase0.523
Mapk14mitogen-activated protein kinase 140.523
SrcRous sarcoma oncogene0.505
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.492
Mdm2transformed mouse 3T3 cell double minute 20.481
Casp1caspase 10.481
Irgm2immunity-related GTPase family M member 20.466
Nf1neurofibromatosis 10.462
Ifi47interferon gamma inducible protein 470.447
Raf1v-raf-leukemia viral oncogene 10.434
Tgtp2T-cell specific GTPase 20.432
Mapkap1mitogen-activated protein kinase associated protein 10.428
Becn1beclin 1, autophagy related0.408
Ctsdcathepsin D0.405
Tsc2tuberous sclerosis 20.400
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.380
Gbp3guanylate binding protein 30.369
Atg3autophagy-related 3 (yeast)0.343
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.320
Irgm1immunity-related GTPase family M member 10.315
Lyz2lysozyme 20.313
Prkceprotein kinase C, epsilon0.300
Trp53transformation related protein 530.296
Foxo1forkhead box O10.284
Cftrcystic fibrosis transmembrane conductance regulator homolog0.266
Mapk1mitogen-activated protein kinase 10.265
Foxa2forkhead box A20.253
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.251
Gabarapgamma-aminobutyric acid receptor associated protein0.251
Gbp5guanylate binding protein 50.246
Gabarapl1gamma-aminobutyric acid (GABA) A receptor-associated protein-like 10.246
Leprleptin receptor0.238
Irs2insulin receptor substrate 20.238
Nr3c1nuclear receptor subfamily 3, group C, member 10.231
Mapk8ip3mitogen-activated protein kinase 8 interacting protein 30.221
Tgfbr1transforming growth factor, beta receptor I0.220
Fkbp8FK506 binding protein 80.216
Ifih1interferon induced with helicase C domain 10.212
Igbp1immunoglobulin (CD79A) binding protein 10.209
Cd40CD40 antigen0.200
Lpin1lipin 10.196
Ctslcathepsin L0.195
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.191
Apcadenomatosis polyposis coli0.191
Mndalmyeloid nuclear differentiation antigen like0.180
Pnpla2patatin-like phospholipase domain containing 20.179
Ptk2PTK2 protein tyrosine kinase 20.176
Wbp2WW domain binding protein 20.169
Atg13ATG13 autophagy related 13 homolog (S. cerevisiae)0.169
Csf1colony stimulating factor 1 (macrophage)0.159
Arntlaryl hydrocarbon receptor nuclear translocator-like0.159
Wdr45WD repeat domain 450.157
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.152
Atg5autophagy-related 5 (yeast)0.152
Wdr81WD repeat domain 810.151
Map1lc3bmicrotubule-associated protein 1 light chain 3 beta0.151
Pim3proviral integration site 30.151
Rac1RAS-related C3 botulinum substrate 10.147
Ypel3yippee-like 3 (Drosophila)0.146
Trp73transformation related protein 730.145
Rptorregulatory associated protein of MTOR, complex 10.143
Map2k4mitogen-activated protein kinase kinase 40.142
Traf6TNF receptor-associated factor 60.141
Plcg1phospholipase C, gamma 10.140
Rxraretinoid X receptor alpha0.139
Hbb-b1hemoglobin, beta adult major chain0.139
Ikbkginhibitor of kappaB kinase gamma0.136
Sav1salvador homolog 1 (Drosophila)0.136
Rfwd2ring finger and WD repeat domain 20.133
Shc1src homology 2 domain-containing transforming protein C10.133
Ngpneutrophilic granule protein0.133
Irf1interferon regulatory factor 10.132
Nf2neurofibromatosis 20.130
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Tmbim6transmembrane BAX inhibitor motif containing 60.275
St13suppression of tumorigenicity 130.174
Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform0.162
Eef2eukaryotic translation elongation factor 20.124
Jak1Janus kinase 10.105
Arf1ADP-ribosylation factor 10.085
Gna12guanine nucleotide binding protein (G protein) alpha 120.082
Ctsl1cathepsin L10.060
Ctsdcathepsin D0.050
Map2k1mitogen activated protein kinase kinase 10.048
Ubqln1ubiquilin 10.044
Ptov1prostate tumor overexpressed 10.042
Cyth1cytohesin 10.041
Atp6v1b2ATPase, H transporting, lysosomal V1 subunit B20.041
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.034
Taf10TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor0.034
Strapserine/threonine kinase receptor associated protein0.034
Trim23tripartite motif-containing 230.031
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.030
Pdp1pyruvate dehyrogenase phosphatase catalytic subunit 10.030
Fbxo3F-box protein 30.029
Rab1bRAB1B, member RAS oncogene family0.028
Casp3caspase 30.028
Grinaglutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)0.027
Ghitmgrowth hormone inducible transmembrane protein0.026
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.026
Akt2v-akt murine thymoma viral oncogene homolog 20.025
Rab5aRAB5A, member RAS oncogene family0.025
Stxbp3syntaxin binding protein 30.024
Gja1gap junction protein, alpha 10.024
Syngr2synaptogyrin 20.024
LOC362855P550.023
Zfand6zinc finger, AN1-type domain 60.023
Usf2upstream transcription factor 2, c-fos interacting0.022
Hbp1HMG-box transcription factor 10.021
Psapprosaposin0.021
Dcaf7DDB1 and CUL4 associated factor 70.020
Morf4l2mortality factor 4 like 20.020
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.020
Cacnb3calcium channel, voltage-dependent, beta 3 subunit0.020
Rab11aRAB11a, member RAS oncogene family0.020
Glulglutamate-ammonia ligase (glutamine synthetase)0.020
Ftlferritin, light polypeptide0.019
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.018
Ppp2r2aprotein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform0.018
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.018
Snx4sorting nexin 40.017
Criptcysteine-rich PDZ-binding protein0.017
Bnip3lBCL2/adenovirus E1B interacting protein 3-like0.017
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.017
Tm9sf4transmembrane 9 superfamily protein member 40.017
Cox8acytochrome c oxidase subunit VIIIa0.017
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.017
Chd6chromodomain helicase DNA binding protein 60.016
Dnm1ldynamin 1-like0.016
Ube2bubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae)0.016
Ccr1chemokine (C-C motif) receptor 10.016
Pdia3protein disulfide isomerase family A, member 30.015
Bet1blocked early in transport 1 homolog (S. cerevisiae)0.015
Papss13'-phosphoadenosine 5'-phosphosulfate synthase 10.015
Ap2s1adaptor-related protein complex 2, sigma 1 subunit0.014
Ptprcprotein tyrosine phosphatase, receptor type, C0.014
Flcnfolliculin0.014
Foxd4forkhead box D40.014
Jtbjumping translocation breakpoint0.014
Vdac1voltage-dependent anion channel 10.014
Rab4aRAB4A, member RAS oncogene family0.014
Nmt1N-myristoyltransferase 10.014
Lifrleukemia inhibitory factor receptor alpha0.013
Mapk6mitogen-activated protein kinase 60.013
Copb1coatomer protein complex, subunit beta 10.013
Vegfavascular endothelial growth factor A0.013
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.013
P4hbprolyl 4-hydroxylase, beta polypeptide0.013
Ppm1aprotein phosphatase 1A, magnesium dependent, alpha isoform0.013
Adaradenosine deaminase, RNA-specific0.013
Akap1A kinase (PRKA) anchor protein 10.013
Snap23synaptosomal-associated protein 230.013
Hist1h1ahistone cluster 1, H1a0.013
Ptpn18protein tyrosine phosphatase, non-receptor type 180.013
Dnajc5DnaJ (Hsp40) homolog, subfamily C, member 50.012
Ube2aubiquitin-conjugating enzyme E2A (RAD6 homolog)0.012
Calm3calmodulin 30.012
CnbpCCHC-type zinc finger, nucleic acid binding protein0.012
Sqstm1sequestosome 10.012
Rab11bRAB11B, member RAS oncogene family0.012
Psmd2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.012
Ensaendosulfine alpha0.012
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.012
Gria2glutamate receptor, ionotropic, AMPA 20.012
Sgtasmall glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha0.012
Cyfip2cytoplasmic FMR1 interacting protein 20.012
Camk4calcium/calmodulin-dependent protein kinase IV0.012
Ngly1N-glycanase 10.012
Ndfip2Nedd4 family interacting protein 20.012
Arl11ADP-ribosylation factor-like 110.011
Snx3sorting nexin 30.011
Capza2capping protein (actin filament) muscle Z-line, alpha 20.011
Scamp1secretory carrier membrane protein 10.011
Dctn1dynactin 10.011
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
ATG1Atg1p0.999
ATG13Atg13p0.998
SNX4Snx4p0.995
ATG20Atg20p0.991
ATG12Atg12p0.987
ATG29Atg29p0.982
ATG21Atg21p0.980
ATG9Atg9p0.976
ATG11Atg11p0.948
KSP1Ksp1p0.946
VAC8Vac8p0.945
ATG3Atg3p0.943
SLT2Slt2p0.934
CDC55Cdc55p0.934
SLG1Slg1p0.927
ATG4Atg4p0.913
ATG23Atg23p0.911
ATG16Atg16p0.899
ATG7Atg7p0.893
TOR1Tor1p0.889
VPS41Vps41p0.885
ATG14Atg14p0.870
HSV2Hsv2p0.848
ATG5Atg5p0.826
SEC2Sec2p0.823
VAM3Vam3p0.784
YPT1Ypt1p0.783
CIS1Cis1p0.768
ATG8Atg8p0.766
COG6Cog6p0.762
ATG2Atg2p0.759
CCZ1Ccz1p0.756
ESA1Esa1p0.730
PHO81Pho81p0.725
ATG18Atg18p0.714
ATG26Atg26p0.683
VTC3Vtc3p0.669
MON1Mon1p0.608
VTC1Vtc1p0.606
VAM7Vam7p0.583
SEC17Sec17p0.573
KOG1Kog1p0.555
VPS30Vps30p0.550
PHO85Pho85p0.524
ARG82Arg82p0.498
VPS3Vps3p0.493
BRE5Bre5p0.484
VPS36Vps36p0.483
YKT6Ykt6p0.478
VAM6Vam6p0.465
SEC4Sec4p0.454
YIL165Chypothetical protein0.453
TCO89Tco89p0.451
NPR2Npr2p0.449
PKH2Pkh2p0.423
VTC4Vtc4p0.419
MKS1Mks1p0.413
PEP5Pep5p0.409
CAK1Cak1p0.402
KIN2Kin2p0.389
VPS16Vps16p0.362
VTC2Vtc2p0.358
VPS38Vps38p0.350
VTI1Vti1p0.344
TPK1Tpk1p0.315
BMH1Bmh1p0.312
ATG10Atg10p0.285
ATG15Atg15p0.276
YPL247Chypothetical protein0.273
PIK1Pik1p0.269
SSK1Ssk1p0.266
PBS2Pbs2p0.251
VPS15Vps15p0.247
TLG2Tlg2p0.245
RTS3Rts3p0.237
COT1Cot1p0.236
GTR1Gtr1p0.229
NUP170Nup170p0.227
ATG19Atg19p0.222
TRS85Trs85p0.219
BCK1Bck1p0.209
MDM10Mdm10p0.209
PTC1Ptc1p0.207
PPZ1Ppz1p0.207
YPL260Whypothetical protein0.202
PTC6Ptc6p0.193
SHP1Shp1p0.191
YIP4Yip4p0.189
HOG1Hog1p0.185
SAP185Sap185p0.185
SEC21Sec21p0.184
CLN1Cln1p0.181
RPO21Rpo21p0.179
PEP12Pep12p0.176
NYV1Nyv1p0.175
ICY2Icy2p0.173
HSP31Hsp31p0.172
AKL1Akl1p0.170
VPS28Vps28p0.168
STB3Stb3p0.166