The network for 'secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

secretion

The controlled release of a substance by a cell or a tissue.

NameDescriptionProbabilityFunc Analog Organism
vab-3Protein VAB-30.632
pkg-1Protein PKG-10.569
unc-9Protein UNC-90.546
abl-1Protein ABL-10.494
egl-30Protein EGL-300.445
nhr-2Protein NHR-20.385
nlg-1Protein NLG-10.364
eat-6Protein EAT-60.354
lit-1Protein LIT-10.353
hlh-2Protein HLH-20.350
CELE_Y57G11C.15Protein Y57G11C.150.349
sec-23Protein SEC-230.294
his-46Protein HIS-460.288
sol-1Protein SOL-10.286
acl-14Protein ACL-140.275
trap-1Protein TRAP-10.255
cka-2Protein CKA-20.253
unc-7Protein UNC-70.250
his-1Protein HIS-10.245
sel-9Protein SEL-90.241
plp-1Protein PLP-10.233
unc-32Protein UNC-320.232
calu-1Protein CALU-10.229
sem-5Protein SEM-50.226
trap-4Protein TRAP-40.225
pde-4Protein PDE-40.218
sec-24.1Protein SEC-24.10.207
clic-1Protein CLIC-10.204
egl-18Protein EGL-180.202
sdz-28Protein SDZ-280.201
lec-1Protein LEC-10.188
lin-11Protein LIN-110.183
adt-2Protein ADT-20.182
T23B12.6Protein T23B12.60.182
sqv-4Protein SQV-40.181
his-5Protein HIS-50.178
unc-54Protein UNC-540.177
pqn-89Protein PQN-890.175
inx-1Protein INX-10.170
aex-3Protein AEX-30.168
ribo-1Protein RIBO-10.167
his-50Protein HIS-500.165
gpb-1Protein GPB-10.164
pxf-1Protein PXF-10.164
dig-1Protein DIG-10.162
plc-1Protein PLC-10.161
syg-1Protein SYG-10.159
F28E10.1Protein F28E10.10.158
unc-60Protein UNC-600.157
egal-1Protein EGAL-10.155
lin-7Protein LIN-70.150
vha-8Protein VHA-80.150
F59E10.3Protein F59E10.30.146
tram-1Protein TRAM-10.146
apg-1Protein APG-10.145
let-60Protein LET-600.143
cmd-1Protein CMD-10.142
CELE_T04H1.2Protein T04H1.20.142
CELE_F17C11.10Protein F17C11.100.142
unc-52Protein UNC-520.141
cal-4Protein CAL-40.141
madd-4Protein MADD-40.137
unc-43Protein UNC-430.137
pept-1Protein PEPT-10.136
sdha-1Protein SDHA-10.135
fat-2Protein FAT-20.135
tba-4Protein TBA-40.135
egl-15Protein EGL-150.135
unc-36Protein UNC-360.134
his-64Protein HIS-640.133
T14G10.5Protein T14G10.50.132
dnj-27Protein DNJ-270.128
egl-8Protein EGL-80.128
abts-3Protein ABTS-30.127
ZK686.3Protein ZK686.30.127
rsd-3Protein RSD-30.126
unc-47Protein UNC-470.125
tpa-1Protein TPA-10.124
unc-112Protein UNC-1120.123
T20B12.7Protein T20B12.70.123
CELE_C08H9.2Protein C08H9.20.122
ZK632.12Protein ZK632.120.121
vps-33.1Protein VPS-33.10.121
egl-27Protein EGL-270.120
clec-62Protein CLEC-620.120
nac-2Protein NAC-20.119
cyp-35A3Protein CYP-35A30.118
apb-1Protein APB-10.118
unc-13Protein UNC-130.117
zoo-1Protein ZOO-10.117
vha-9Protein VHA-90.116
inx-12Protein INX-120.116
dkf-2Protein DKF-20.116
mdf-2Protein MDF-20.116
pdl-1Protein PDL-10.115
fbxc-5Protein FBXC-50.115
glp-1Protein GLP-10.115
K03E6.7Protein K03E6.70.114
F44A2.5Protein F44A2.50.113
asp-6Protein ASP-60.113
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
GluRIIAGlutamate receptor IIA0.993
EcREcdysone receptor0.987
Rac1CG2248 gene product from transcript CG2248-RA0.983
Pink1PTEN-induced putative kinase 10.924
brpbruchpilot0.913
witwishful thinking0.859
mbcmyoblast city0.818
wlswntless0.817
unc-104CG8566 gene product from transcript CG8566-RB0.811
jebjelly belly0.769
StamSignal transducing adaptor molecule0.769
Pp2B-14DProtein phosphatase 2B at 14D0.758
phlpole hole0.610
norpAno receptor potential A0.602
PknProtein kinase related to protein kinase N0.591
Atg1Autophagy-specific gene 10.568
CG34400CG34400 gene product from transcript CG34400-RD0.565
par-1CG8201 gene product from transcript CG8201-RA0.555
Dcr-2Dicer-20.553
atlatlastin0.548
CaMKIICalcium/calmodulin-dependent protein kinase II0.534
hthhomothorax0.533
CdsACDP diglyceride synthetase0.514
Tsc1CG6147 gene product from transcript CG6147-RA0.482
fz2frizzled 20.465
KaiRIACG18039 gene product from transcript CG18039-RA0.460
chicchickadee0.447
Hnf4Hepatocyte nuclear factor 40.447
Frq1Frequenin 10.446
Snap25Synapse protein 250.446
Khc-73Kinesin-730.442
rheaCG6831 gene product from transcript CG6831-RA0.432
14-3-3zetaCG17870 gene product from transcript CG17870-RB0.416
Rab11Rab-protein 110.416
ptcpatched0.398
certceramide transfer protein0.386
CkIIalphaCasein kinase II alpha subunit0.385
Rab7Rab-protein 70.383
discodisconnected0.371
unc-13CG2999 gene product from transcript CG2999-RA0.371
deltaCOPdelta-coatomer protein0.368
AdoRAdenosine receptor0.367
MoeMoesin0.366
shishibire0.352
Rab5Rab-protein 50.346
NrgNeuroglian0.341
sevsevenless0.341
pumpumilio0.339
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.326
SnapSoluble NSF attachment protein0.322
forforaging0.320
spasspastin0.319
nejnejire0.314
eyaeyes absent0.309
CatsupCatecholamines up0.309
stjstraightjacket0.301
DadDaughters against dpp0.290
ActbetaActivin-beta0.289
TequilaCG4821 gene product from transcript CG4821-RE0.287
Src42ASrc oncogene at 42A0.283
SerSerrate0.282
TbhTyramine beta hydroxylase0.281
lqfliquid facets0.272
Itp-r83AInositol 1,4,5,-tris-phosphate receptor0.268
cnkconnector enhancer of ksr0.262
SybSynaptobrevin0.260
eglegalitarian0.258
ftz-f1ftz transcription factor 10.255
kibrakibra ortholog0.247
wunwunen0.245
sggshaggy0.244
mnbminibrain0.243
OsbpOxysterol binding protein0.242
UbxUltrabithorax0.237
Syx5Syntaxin 50.235
endoAendophilin A0.230
Syx1ASyntaxin 1A0.227
CG32635CG32635 gene product from transcript CG32635-RA0.227
hiwhighwire0.226
diadiaphanous0.226
ImpIGF-II mRNA-binding protein0.221
wgwingless0.219
rprreaper0.217
jarjaguar0.216
IppInositol polyphosphate 1-phosphatase0.213
trioCG18214 gene product from transcript CG18214-RA0.213
CG10566CG10566 gene product from transcript CG10566-RA0.213
Stat92ESignal-transducer and activator of transcription protein at 92E0.211
Syt1Synaptotagmin 10.209
VAChTCG32848 gene product from transcript CG32848-RA0.205
l(1)dd4lethal (1) discs degenerate 40.200
apapterous0.196
Nrx-1Neurexin 10.195
neuroliginCG13772 gene product from transcript CG13772-RA0.190
MerMerlin0.189
emcextra macrochaetae0.188
CG9339CG9339 gene product from transcript CG9339-RG0.185
mavmaverick0.184
Ac3CG1506 gene product from transcript CG1506-RA0.182
Gp150CG5820 gene product from transcript CG5820-RA0.181
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor0.998
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.997
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.992
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.989
SHC1SHC (Src homology 2 domain containing) transforming protein 10.984
PTPN1protein tyrosine phosphatase, non-receptor type 10.982
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.976
VIMvimentin0.963
SMAD2SMAD family member 20.961
CASKcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.957
FGFR2fibroblast growth factor receptor 20.957
SNAP23synaptosomal-associated protein, 23kDa0.948
RAB5ARAB5A, member RAS oncogene family0.923
PRKCAprotein kinase C, alpha0.913
RAB1ARAB1A, member RAS oncogene family0.910
INSRinsulin receptor0.909
SNCAsynuclein, alpha (non A4 component of amyloid precursor)0.906
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.906
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.903
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.894
ARRB2arrestin, beta 20.893
EPS15epidermal growth factor receptor pathway substrate 150.878
RABAC1Rab acceptor 1 (prenylated)0.874
APPamyloid beta (A4) precursor protein0.870
TMED10transmembrane emp24-like trafficking protein 10 (yeast)0.870
CRHR1corticotropin releasing hormone receptor 10.863
CAV1caveolin 1, caveolae protein, 22kDa0.860
TAL1T-cell acute lymphocytic leukemia 10.849
CLNS1Achloride channel, nucleotide-sensitive, 1A0.848
CCR2chemokine (C-C motif) receptor 20.840
RNF11ring finger protein 110.839
KCNJ4potassium inwardly-rectifying channel, subfamily J, member 40.837
CCL4chemokine (C-C motif) ligand 40.834
TEKTEK tyrosine kinase, endothelial0.830
CD2APCD2-associated protein0.829
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.825
NAPAN-ethylmaleimide-sensitive factor attachment protein, alpha0.814
OCRLoculocerebrorenal syndrome of Lowe0.808
FN1fibronectin 10.803
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.797
ENGendoglin0.797
ABCC8ATP-binding cassette, sub-family C (CFTR/MRP), member 80.793
ANXA1annexin A10.791
FGFR1fibroblast growth factor receptor 10.788
IL8interleukin 80.788
LATlinker for activation of T cells0.786
SNAP25synaptosomal-associated protein, 25kDa0.783
IFNGinterferon, gamma0.781
CCR5chemokine (C-C motif) receptor 50.765
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.764
COPB1coatomer protein complex, subunit beta 10.754
DLG1discs, large homolog 1 (Drosophila)0.744
RUNX1runt-related transcription factor 10.734
MED15mediator complex subunit 150.734
FGBfibrinogen beta chain0.732
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.727
HTThuntingtin0.723
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.719
LRRK2leucine-rich repeat kinase 20.707
IL10interleukin 100.695
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.695
GABBR2gamma-aminobutyric acid (GABA) B receptor, 20.692
NSFN-ethylmaleimide-sensitive factor0.689
BTN3A2butyrophilin, subfamily 3, member A20.687
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.684
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.681
PDCD6IPprogrammed cell death 6 interacting protein0.681
ARCN1archain 10.671
CXCL9chemokine (C-X-C motif) ligand 90.670
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.663
CCR1chemokine (C-C motif) receptor 10.651
FGF1fibroblast growth factor 1 (acidic)0.645
COPGcoatomer protein complex, subunit gamma0.645
GAB1GRB2-associated binding protein 10.645
S100A9S100 calcium binding protein A90.642
HLA-DRB1major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 10.642
ANXA2annexin A20.619
AHRaryl hydrocarbon receptor0.618
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.616
NCF1neutrophil cytosolic factor 10.611
GRM1glutamate receptor, metabotropic 10.608
GDI2GDP dissociation inhibitor 20.605
FGF8fibroblast growth factor 8 (androgen-induced)0.590
SLC6A7solute carrier family 6 (neurotransmitter transporter, L-proline), member 70.586
CHRNA4cholinergic receptor, nicotinic, alpha 40.585
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.579
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.579
FCER1GFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.571
AP1G1adaptor-related protein complex 1, gamma 1 subunit0.570
AP2B1adaptor-related protein complex 2, beta 1 subunit0.569
C1QAcomplement component 1, q subcomponent, A chain0.568
ICAM1intercellular adhesion molecule 10.567
BTN3A3butyrophilin, subfamily 3, member A30.567
PDX1pancreatic and duodenal homeobox 10.563
UBQLN1ubiquilin 10.562
ARRB1arrestin, beta 10.560
HSPA1Bheat shock 70kDa protein 1B0.560
IL2RBinterleukin 2 receptor, beta0.553
RABEP1rabaptin, RAB GTPase binding effector protein 10.551
ZFYVE9zinc finger, FYVE domain containing 90.550
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Chrna7cholinergic receptor, nicotinic, alpha 70.774
Syt4synaptotagmin IV0.723
Gng7guanine nucleotide binding protein (G protein), gamma 70.695
Pcsk1proprotein convertase subtilisin/kexin type 10.662
Trhr2thyrotropin releasing hormone receptor 20.642
Csf1colony stimulating factor 1 (macrophage)0.638
Avparginine vasopressin0.626
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.603
Olr1641olfactory receptor 16410.596
Acrv1acrosomal vesicle protein 10.590
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.589
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.578
Cxcl10chemokine (C-X-C motif) ligand 100.573
Gria1glutamate receptor, ionotropic, AMPA 10.565
Prkcgprotein kinase C, gamma0.564
Ptger2prostaglandin E receptor 2 (subtype EP2)0.551
Dlg4discs, large homolog 4 (Drosophila)0.539
Dlgap1discs, large (Drosophila) homolog-associated protein 10.530
Syn2synapsin II0.529
Acsl4acyl-CoA synthetase long-chain family member 40.521
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.519
Snap25synaptosomal-associated protein 250.517
Accn2amiloride-sensitive cation channel 2, neuronal0.505
Slc14a2solute carrier family 14 (urea transporter), member 20.501
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.494
Pde1bphosphodiesterase 1B, calmodulin-dependent0.493
Pnocprepronociceptin0.492
Edn2endothelin 20.488
Htr75-hydroxytryptamine (serotonin) receptor 70.483
Gjb4gap junction protein, beta 40.482
Cyp4a8cytochrome P450, family 4, subfamily a, polypeptide 80.481
L1camL1 cell adhesion molecule0.478
Lim2lens intrinsic membrane protein 20.476
B3gat1beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)0.473
Kcnc2potassium voltage gated channel, Shaw-related subfamily, member 20.465
Myt1lmyelin transcription factor 1-like0.463
Pmfbp1polyamine modulated factor 1 binding protein 10.463
Il1binterleukin 1 beta0.457
Pcdhb12protocadherin beta 120.451
Grin2dglutamate receptor, ionotropic, N-methyl D-aspartate 2D0.447
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.447
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.445
Pnliprp2pancreatic lipase-related protein 20.443
Agtr1aangiotensin II receptor, type 1a0.435
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.434
Ccl3chemokine (C-C motif) ligand 30.432
Ahsgalpha-2-HS-glycoprotein0.432
Cd80Cd80 molecule0.432
Mmp3matrix metallopeptidase 30.430
Nfascneurofascin0.429
Olr287olfactory receptor 2870.423
Mmp10matrix metallopeptidase 100.423
Kcna6potassium voltage gated channel, shaker related subfamily, member 60.420
Zg16zymogen granule protein 160.417
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.417
Nos2nitric oxide synthase 2, inducible0.417
Syn1synapsin I0.412
Syt3synaptotagmin III0.409
Apba2amyloid beta (A4) precursor protein-binding, family A, member 20.409
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.406
Mylk2myosin light chain kinase 20.405
Arandrogen receptor0.405
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.401
Prlprolactin0.400
Vamp1vesicle-associated membrane protein 10.393
Fgf14fibroblast growth factor 140.390
Vipvasoactive intestinal peptide0.389
Hrh4histamine receptor H40.382
Vegp1von Ebners gland protein 10.381
Cacng4calcium channel, voltage-dependent, gamma subunit 40.376
RGD1310262hypothetical LOC3046500.376
Itgamintegrin, alpha M0.375
Mapk10mitogen activated protein kinase 100.374
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.373
Ptafrplatelet-activating factor receptor0.366
Phkg1phosphorylase kinase, gamma 10.365
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.364
Adora1adenosine A1 receptor0.363
Ucp3uncoupling protein 3 (mitochondrial, proton carrier)0.359
Ttltubulin tyrosine ligase0.357
CamkvCaM kinase-like vesicle-associated0.355
Kcnj9potassium inwardly-rectifying channel, subfamily J, member 90.355
Sstr1somatostatin receptor 10.353
Pex5lperoxisomal biogenesis factor 5-like0.351
Foxe3forkhead box E30.351
Gria2glutamate receptor, ionotropic, AMPA 20.350
Gnao1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.349
Slc28a1solute carrier family 28 (sodium-coupled nucleoside transporter), member 10.346
Gipgastric inhibitory polypeptide0.344
Adrb1adrenergic, beta-1-, receptor0.344
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.343
Oprm1opioid receptor, mu 10.342
Stxbp1syntaxin binding protein 10.341
Hnmthistamine N-methyltransferase0.341
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.338
Ccl2chemokine (C-C motif) ligand 20.336
S100a8S100 calcium binding protein A80.335
Prap1proline-rich acidic protein 10.335
Apoa4apolipoprotein A-IV0.329
Slc5a2solute carrier family 5 (sodium/glucose cotransporter), member 20.326
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
SSO1Sso1p0.880
SEC8Sec8p0.868
SEC1Sec1p0.827
YPT1Ypt1p0.815
SEC6Sec6p0.809
EXO70Exo70p0.807
SRO7Sro7p0.769
SEC5Sec5p0.722
EXO84Exo84p0.680
ERP4Erp4p0.664
SEC4Sec4p0.662
VPS21Vps21p0.585
VTI1Vti1p0.583
YPT31Ypt31p0.536
CHS5Chs5p0.526
ERP5Erp5p0.485
SEC15Sec15p0.472
MSO1Mso1p0.430
VPS45Vps45p0.379
SEC9Sec9p0.376
SEC10Sec10p0.368
SEC21Sec21p0.332
OSH6Osh6p0.312
YRA1Yra1p0.299
SSA3Ssa3p0.273
ARK1Ark1p0.266
SEC3Sec3p0.255
END3End3p0.237
GPA2Gpa2p0.235
SPA2Spa2p0.234
ROM2Rom2p0.225
SEC2Sec2p0.220
CNB1Cnb1p0.220
BNI1Bni1p0.203
USO1Uso1p0.191
YPT6Ypt6p0.188
PIL1Pil1p0.183
MCA1Mca1p0.161
CSN9Csn9p0.159
YIP3Yip3p0.158
OSH7Osh7p0.156
BMH2Bmh2p0.155
SSO2Sso2p0.142
SSK2Ssk2p0.139
OLE1Ole1p0.129
NCR1Ncr1p0.127
AKL1Akl1p0.124
NUM1Num1p0.123
GCS1Gcs1p0.118
VPS36Vps36p0.118
YJL045Whypothetical protein0.110
CDC11Cdc11p0.110
SNC2Snc2p0.107
YPT52Ypt52p0.106
RIM21Rim21p0.104
YIP1Yip1p0.104
GDI1Gdi1p0.101
MUK1Muk1p0.101
CPR7Cpr7p0.096
GYP5Gyp5p0.095
PDR12Pdr12p0.089
PSK1Psk1p0.086
RHO1Rho1p0.086
PAN1Pan1p0.086
YOR1Yor1p0.086
AUR1Aur1p0.082
ADY2Ady2p0.082
BDH1Bdh1p0.081
MEH1Meh1p0.079
SCS2Scs2p0.078
SSA4Ssa4p0.077
SHS1Shs1p0.075
KTI11Kti11p0.075
VPS13Vps13p0.075
XKS1Xks1p0.074
PRP19Prp19p0.072
DRS2Drs2p0.071
RSN1Rsn1p0.070
STE24Ste24p0.069
SLA2Sla2p0.068
RFA2Rfa2p0.066
VAC8Vac8p0.065
KAR2Kar2p0.065
AKR2Akr2p0.065
POG1Pog1p0.065
VAM7Vam7p0.064
SAM2Sam2p0.064
MKT1Mkt1p0.062
YPR097Whypothetical protein0.062
KIN1Kin1p0.062
CSI1Csi1p0.061
IZH4Izh4p0.061
SAP4Sap4p0.060
POX1Pox1p0.059
BSD2Bsd2p0.059
RAD7Rad7p0.059
RDI1Rdi1p0.057
TCB3Tcb3p0.057
MSB3Msb3p0.057
TPS3Tps3p0.056