The network for 'regulation of response to stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.994
vab-3Protein VAB-30.949
unc-9Protein UNC-90.834
par-5Protein PAR-50.818
sax-3Protein SAX-30.785
lit-1Protein LIT-10.774
pha-4Protein PHA-40.753
eps-8Protein EPS-80.752
unc-40Protein UNC-400.722
ida-1Protein IDA-10.719
unc-43Protein UNC-430.620
dim-1Protein DIM-10.593
teg-4Protein TEG-40.578
K10D6.4Protein K10D6.40.563
unc-62Protein UNC-620.559
sgn-1Protein SGN-10.553
che-3Protein CHE-30.533
bar-1Protein BAR-10.522
atn-1Protein ATN-10.518
nlg-1Protein NLG-10.517
acs-4Protein ACS-40.511
soc-2Protein SOC-20.509
daf-14Protein DAF-140.501
lin-25Protein LIN-250.499
pes-7Protein PES-70.489
itr-1Protein ITR-10.489
csn-5Protein CSN-50.477
plc-1Protein PLC-10.471
pkg-1Protein PKG-10.464
pry-1Protein PRY-10.435
sng-1Protein SNG-10.424
bir-1Protein BIR-10.423
ten-1Protein TEN-10.423
eor-2Protein EOR-20.415
lev-8Protein LEV-80.409
alp-1Protein ALP-10.406
swan-2Protein SWAN-20.404
mpz-2Protein MPZ-20.400
ifd-1Protein IFD-10.399
let-60Protein LET-600.399
egl-27Protein EGL-270.396
mig-5Protein MIG-50.391
mat-3Protein MAT-30.390
alx-1Protein ALX-10.376
odr-3Protein ODR-30.376
sma-1Protein SMA-10.374
let-607Protein LET-6070.373
hmp-2Protein HMP-20.372
daf-12Protein DAF-120.366
F45E4.3Protein F45E4.30.363
dpy-31Protein DPY-310.361
akt-1Protein AKT-10.357
unc-32Protein UNC-320.357
lag-1Protein LAG-10.356
gar-3Protein GAR-30.352
inx-13Protein INX-130.350
mig-2Protein MIG-20.348
frm-7Protein FRM-70.341
osm-5Protein OSM-50.337
msp-55Protein MSP-550.336
skn-1Protein SKN-10.335
unc-52Protein UNC-520.335
nipi-3Protein NIPI-30.334
C14B9.2Protein C14B9.20.333
daf-6Protein DAF-60.332
daf-19Protein DAF-190.331
apr-1Protein APR-10.330
sup-12Protein SUP-120.330
ehbp-1Protein EHBP-10.328
sad-1Protein SAD-10.323
C05D10.4Protein C05D10.40.323
CELE_F14E5.2Protein F14E5.20.322
che-2Protein CHE-20.322
T28F4.1Protein T28F4.10.320
F59A3.4Protein F59A3.40.317
mom-2Protein MOM-20.316
C54E4.2Protein C54E4.20.315
ubr-1Protein UBR-10.315
goa-1Protein GOA-10.314
let-418Protein LET-4180.314
eor-1Protein EOR-10.312
mec-2Protein MEC-20.310
npp-7Protein NPP-70.308
egl-13Protein EGL-130.308
daf-11Protein DAF-110.306
mig-38Protein MIG-380.306
scd-1Protein SCD-10.300
C13F10.4Protein C13F10.40.300
K06A9.1Protein K06A9.10.300
pal-1Protein PAL-10.299
ceh-44Protein CEH-440.295
gld-1Protein GLD-10.295
smp-1Protein SMP-10.292
lin-17Protein LIN-170.291
kin-4Protein KIN-40.290
sea-2Protein SEA-20.289
lev-11Protein LEV-110.287
flt-1Protein FLT-10.285
nhr-45Protein NHR-450.284
unc-7Protein UNC-70.283
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
chdchordin0.999
ntlano tail a0.998
gli2aGLI-Kruppel family member GLI2a0.994
dlddeltaD0.994
ndr2nodal-related 20.988
gli1GLI-Kruppel family member 10.987
crabp2acellular retinoic acid binding protein 2, a0.982
efnb2aephrin B2a0.966
tbx6T-box gene 60.966
irx3airoquois homeobox protein 3a0.961
pkd2polycystic kidney disease 20.952
bmp2bbone morphogenetic protein 2b0.945
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.944
flhfloating head0.944
wnt11wingless-type MMTV integration site family, member 110.937
tll1tolloid-like 10.922
wnt5bwingless-type MMTV integration site family, member 5b0.920
twist1atwist1a0.912
eomesaeomesodermin homolog a0.907
fgf3fibroblast growth factor 30.901
bmp4bone morphogenetic protein 40.900
fn1fibronectin 10.899
pax8paired box gene 80.899
ascl1aachaete-scute complex-like 1a (Drosophila)0.898
ntn1bnetrin 1b0.896
fgf8afibroblast growth factor 8 a0.892
shhasonic hedgehog a0.879
dharmadharma0.878
cyp26a1cytochrome P450, subfamily XXVIA, polypeptide 10.876
lhx1aLIM homeobox 1a0.874
tcf7l1atranscription factor 7-like 1a (T-cell specific, HMG-box)0.863
dab1adisabled homolog 1a (Drosophila)0.862
brd4bromodomain containing 40.860
gpc4glypican 40.858
dusp6dual specificity phosphatase 60.858
id1inhibitor of DNA binding 10.856
pea3ETS-domain transcription factor pea30.855
pax2apaired box gene 2a0.848
bmp2abone morphogenetic protein 2a0.844
bmp7abone morphogenetic protein 7a0.843
adra2aadrenergic, alpha-2A-, receptor0.841
gro1groucho 10.840
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.837
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.829
foxh1forkhead box H10.822
pard6gbpar-6 partitioning defective 6 homolog gamma B (C. elegans)0.821
foxd3forkhead box D30.819
epha4aeph receptor A4a0.819
gata4GATA-binding protein 40.817
cebpaCCAAT/enhancer binding protein (C/EBP), alpha0.813
hmx1H6 homeo box 10.811
hey1hairy/enhancer-of-split related with YRPW motif 10.786
spns2spinster homolog 2 (Drosophila)0.786
fli1afriend leukemia integration 1a0.784
twist3twist30.781
pou5f1POU domain, class 5, transcription factor 10.777
dlcdeltaC0.771
ephb3aeph receptor B3a0.768
myhz2myosin, heavy polypeptide 2, fast muscle specific0.768
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.759
ift88intraflagellar transport 88 homolog0.758
oepone-eyed pinhead0.756
pcdh18bprotocadherin 18b0.755
sf3b1splicing factor 3b, subunit 10.750
mc2rmelanocortin 2 receptor0.749
myogmyogenin0.747
axin1axin 10.744
six3bsine oculis homeobox homolog 3b0.743
amotl2aangiomotin like 2a0.735
snai1bsnail homolog 1b (Drosophila)0.728
mt2metallothionein 20.721
myf5myogenic factor 50.721
dzip1DAZ interacting protein 10.720
tp53tumor protein p530.718
notch2notch homolog 20.718
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.718
mapk1mitogen-activated protein kinase 10.712
hes6hairy and enhancer of split 6 (Drosophila)0.708
fzd7afrizzled homolog 7a0.705
lfnglunatic fringe homolog0.698
gscgoosecoid0.686
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.680
foxa2forkhead box A20.674
wnt11rwingless-type MMTV integration site family, member 11, related0.672
tgfb3transforming growth factor, beta 30.672
disp1dispatched homolog 1 (Drosophila)0.668
fzd10frizzled homolog 100.667
fras1Fraser syndrome 10.667
dkk1bdickkopf 1b0.666
bambiaBMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a0.664
egr2bearly growth response 2b0.659
phox2bpaired-like homeobox 2b0.657
cdx4caudal type homeo box transcription factor 40.656
supt5hsuppressor of Ty 5 homolog (S. cerevisiae)0.652
gata5GATA-binding protein 50.646
tbx16T-box gene 160.644
dccdeleted in colorectal carcinoma0.638
restRE1-silencing transcription factor0.636
gro2groucho 20.635
otpaorthopedia homolog a0.634
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
SLT2Slt2p0.948
SHO1Sho1p0.778
FAR11Far11p0.771
FAR1Far1p0.729
TPK2Tpk2p0.726
VPS64Vps64p0.726
CLA4Cla4p0.660
TPK1Tpk1p0.627
RRI1Rri1p0.604
PSY2Psy2p0.603
SPT16Spt16p0.586
TOR1Tor1p0.556
SLG1Slg1p0.549
HOG1Hog1p0.545
PIL1Pil1p0.537
KSP1Ksp1p0.535
MYO5Myo5p0.529
RHO1Rho1p0.524
BCK1Bck1p0.519
YAK1Yak1p0.518
CDC55Cdc55p0.511
MKK1Mkk1p0.507
CTR9Ctr9p0.503
ERP4Erp4p0.499
AKL1Akl1p0.479
FAR8Far8p0.465
CKA1Cka1p0.444
MSN2Msn2p0.438
RIM101Rim101p0.433
MIG1Mig1p0.426
PTC1Ptc1p0.413
FAR3Far3p0.408
UBP15Ubp15p0.406
MYO3Myo3p0.378
KOG1Kog1p0.378
PRB1Prb1p0.365
CDC28Cdc28p0.363
FUS1Fus1p0.360
BBC1Bbc1p0.355
ATG4Atg4p0.349
BEM1Bem1p0.348
CRZ1Crz1p0.338
HSE1Hse1p0.338
ATG13Atg13p0.338
YOL087Chypothetical protein0.338
VPS27Vps27p0.331
ALO1Alo1p0.325
YDJ1Ydj1p0.318
END3End3p0.314
RPN4Rpn4p0.302
SLA2Sla2p0.298
MKS1Mks1p0.296
STE5Ste5p0.293
NET1Net1p0.290
CDC25Cdc25p0.289
CHC1Chc1p0.275
STE11Ste11p0.270
PPZ1Ppz1p0.268
CDC24Cdc24p0.261
YOR1Yor1p0.256
MON1Mon1p0.255
RAD51Rad51p0.244
SSK1Ssk1p0.242
MBR1Mbr1p0.241
PBS2Pbs2p0.241
POL30Pol30p0.231
CDC34Cdc34p0.231
VAM7Vam7p0.230
MDS3Mds3p0.229
VAC8Vac8p0.229
RLM1Rlm1p0.228
EBS1Ebs1p0.227
STE18Ste18p0.222
ADR1Adr1p0.214
FUS3Fus3p0.214
SNT1Snt1p0.210
SET2Set2p0.208
SPA2Spa2p0.208
SSK2Ssk2p0.207
SSE1Sse1p0.204
TRS65Trs65p0.204
VPS4Vps4p0.202
EAF5Eaf5p0.202
SCP1Scp1p0.200
PAF1Paf1p0.195
PTP2Ptp2p0.195
HSV2Hsv2p0.195
HAL5Hal5p0.193
STE20Ste20p0.193
SIR4Sir4p0.193
ROM2Rom2p0.193
CNB1Cnb1p0.190
STE12Ste12p0.190
ENA5Ena5p0.187
SLX5Slx5p0.186
VPS20Vps20p0.181
SLZ1Slz1p0.181
STI1Sti1p0.178
RAD23Rad23p0.178
YPT1Ypt1p0.177