The network for 'establishment of protein localization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

establishment of protein localization

The directed movement of a protein to a specific location.

NameDescriptionProbabilityFunc Analog Organism
unc-52Protein UNC-520.027
sem-5Protein SEM-50.027
npp-7Protein NPP-70.023
egl-44Protein EGL-440.023
egl-8Protein EGL-80.023
pdi-1Protein PDI-10.021
mpk-1Protein MPK-10.021
unc-108Protein UNC-1080.020
chc-1Protein CHC-10.019
sec-23Protein SEC-230.019
hsp-1Protein HSP-10.019
vbh-1Protein VBH-10.019
lin-36Protein LIN-360.018
eftu-2Protein EFTU-20.018
ret-1Protein RET-10.018
klp-7Protein KLP-70.018
acl-14Protein ACL-140.018
par-3Protein PAR-30.018
par-5Protein PAR-50.017
swsn-1Protein SWSN-10.017
let-60Protein LET-600.017
C11E4.6Protein C11E4.60.017
hpo-22Protein HPO-220.017
rpt-3Protein RPT-30.017
pry-1Protein PRY-10.017
rab-5Protein RAB-50.017
CELE_Y59A8A.3Protein Y59A8A.30.017
hum-5Protein HUM-50.017
F44B9.5Protein F44B9.50.017
gei-17Protein GEI-170.017
egl-15Protein EGL-150.016
sma-6Protein SMA-60.016
mat-3Protein MAT-30.016
unc-43Protein UNC-430.016
sqv-4Protein SQV-40.016
R11A8.7Protein R11A8.70.016
syx-17Protein SYX-170.016
unc-44Protein UNC-440.016
mec-2Protein MEC-20.016
rho-1Protein RHO-10.016
C53B4.4Protein C53B4.40.016
skn-1Protein SKN-10.015
hcp-4Protein HCP-40.015
unc-60Protein UNC-600.015
sel-8Protein SEL-80.015
clic-1Protein CLIC-10.015
dnc-2Protein DNC-20.015
dnj-12Protein DNJ-120.015
bub-1Protein BUB-10.015
ubxn-2Protein UBXN-20.015
col-173Protein COL-1730.015
F37C4.4Protein F37C4.40.015
hid-1Protein HID-10.015
T09A5.9Protein T09A5.90.014
lmn-1Protein LMN-10.014
ptc-1Protein PTC-10.014
rpn-3Protein RPN-30.014
M03F8.3Protein M03F8.30.014
rme-4Protein RME-40.014
hlh-30Protein HLH-300.014
sys-1Protein SYS-10.014
rab-11.1Protein RAB-11.10.014
ced-7Protein CED-70.014
rpn-1Protein RPN-10.014
cmd-1Protein CMD-10.014
rab-1Protein RAB-10.014
dys-1Protein DYS-10.014
cct-2Protein CCT-20.014
sad-1Protein SAD-10.014
spc-1Protein SPC-10.014
csnk-1Protein CSNK-10.014
csn-6Protein CSN-60.014
unc-9Protein UNC-90.014
pde-2Protein PDE-20.014
his-35Protein HIS-350.014
che-2Protein CHE-20.014
Y71F9AL.17Protein Y71F9AL.170.014
C13B9.3Protein C13B9.30.014
hif-1Protein HIF-10.014
gpb-1Protein GPB-10.014
vav-1Protein VAV-10.014
atn-1Protein ATN-10.014
mom-5Protein MOM-50.014
kin-3Protein KIN-30.014
T20B12.7Protein T20B12.70.014
CELE_T03F6.3Protein T03F6.30.014
daf-14Protein DAF-140.014
unc-112Protein UNC-1120.014
imb-2Protein IMB-20.014
nuo-3Protein NUO-30.013
vha-8Protein VHA-80.013
hmg-1.1Protein HMG-1.10.013
mlc-5Protein MLC-50.013
cdc-42Protein CDC-420.013
unc-73Protein UNC-730.013
F42C5.9Protein F42C5.90.013
tbc-9Protein TBC-90.013
cls-2Protein CLS-20.013
hrdl-1Protein HRDL-10.013
che-13Protein CHE-130.013
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tp53tumor protein p530.057
bmp2bbone morphogenetic protein 2b0.037
copacoatomer protein complex, subunit alpha0.024
plcg1phospholipase C, gamma 10.021
cdh1cadherin 1, epithelial0.021
anxa1aannexin A1a0.019
krt4keratin 40.019
pycardPYD and CARD domain containing0.017
itgb1b.2integrin, beta 1b.20.017
kdrlkinase insert domain receptor like0.017
mmp2matrix metalloproteinase 20.016
nkx2.2aNK2 transcription factor related 2a0.015
cnn2calponin 20.015
kif23kinesin family member 230.014
plk1polo-like kinase 1 (Drosophila)0.014
llgl2lethal giant larvae homolog 2 (Drosophila)0.013
flhfloating head0.013
runx2arunt-related transcription factor 2a0.013
eif3haeukaryotic translation initiation factor 3, subunit H, a0.013
icnictacalcin0.012
ahctf1AT hook containing transcription factor 10.012
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.012
gna12guanine nucleotide binding protein (G protein) alpha 120.012
ptenbphosphatase and tensin homolog B (mutated in multiple advanced cancers 1)0.012
prkczprotein kinase C, zeta0.012
hspa4aheat shock protein 4a0.011
mapk3mitogen-activated protein kinase 30.011
scribscribbled homolog (Drosophila)0.011
fzd7bfrizzled homolog 7b0.011
col27a1acollagen, type XXVII, alpha 1a0.011
gdf6agrowth differentiation factor 6a0.011
wlswntless homolog (Drosophila)0.011
pkd2polycystic kidney disease 20.011
pak2ap21 (CDKN1A)-activated kinase 2a0.010
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.010
cd63Cd63 antigen0.010
fgf3fibroblast growth factor 30.010
foxa2forkhead box A20.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Ras85DRas oncogene at 85D0.991
dallydivision abnormally delayed0.905
Cdc42CG12530 gene product from transcript CG12530-RA0.882
Nrx-IVNeurexin IV0.825
pucpuckered0.766
l(2)gllethal (2) giant larvae0.764
dcodiscs overgrown0.738
EgfrEpidermal growth factor receptor0.728
slmbsupernumerary limbs0.695
MadMothers against dpp0.679
cpbcapping protein beta0.676
Akt1CG4006 gene product from transcript CG4006-RA0.662
Stat92ESignal-transducer and activator of transcription protein at 92E0.651
drkdownstream of receptor kinase0.639
TER94CG2331 gene product from transcript CG2331-RA0.515
wlswntless0.492
CdsACDP diglyceride synthetase0.482
MoeMoesin0.465
Rab5Rab-protein 50.454
armarmadillo0.454
lqfliquid facets0.432
faffat facets0.432
ovoCG6824 gene product from transcript CG6824-RE0.423
Rac1CG2248 gene product from transcript CG2248-RA0.416
wgwingless0.410
Syx7Syntaxin 70.407
sqhspaghetti squash0.406
Act5CActin 5C0.402
MerMerlin0.400
sktlskittles0.397
Pp4-19CProtein phosphatase 19C0.396
hydhyperplastic discs0.388
pumpumilio0.384
KhcKinesin heavy chain0.361
sinaseven in absentia0.356
lqfRliquid facets-Related0.354
carcarnation0.352
shnschnurri0.338
CaMKIICalcium/calmodulin-dependent protein kinase II0.336
Pp2B-14DProtein phosphatase 2B at 14D0.327
AmphAmphiphysin0.325
rapsrapsynoid0.319
Uba1Ubiquitin activating enzyme 10.319
RanGapRan GTPase activating protein0.312
Dsp1Dorsal switch protein 10.309
cactcactus0.295
aopanterior open0.292
rheaCG6831 gene product from transcript CG6831-RA0.285
Sir2CG5216 gene product from transcript CG5216-RA0.274
LamLamin0.273
trctricornered0.271
inscinscuteable0.267
CG7033CG7033 gene product from transcript CG7033-RC0.265
sdtstardust0.265
chicchickadee0.258
bsblistered0.257
phlpole hole0.257
CG31120CG31120 gene product from transcript CG31120-RB0.252
brpbruchpilot0.250
Hs6stHeparan sulfate 6-O-sulfotransferase0.249
trbltribbles0.247
Lis-1Lissencephaly-10.246
didumdilute class unconventional myosin0.244
NNotch0.242
scbscab0.239
MED6Mediator complex subunit 60.239
bazbazooka0.238
Rab11Rab-protein 110.232
CG11347CG11347 gene product from transcript CG11347-RE0.228
DatDopamine N acetyltransferase0.228
zipzipper0.227
gammaCopgamma-coatomer protein0.222
SdhASuccinate dehydrogenase A0.222
Btk29ABtk family kinase at 29A0.216
saxsaxophone0.214
RhebCG1081 gene product from transcript CG1081-RA0.210
sflsulfateless0.206
witwishful thinking0.199
BicDBicaudal D0.198
PP2A-B'CG7913 gene product from transcript CG7913-RK0.196
CspCysteine string protein0.196
fs(1)K10female sterile (1) K100.196
rutrutabaga0.196
fogfolded gastrulation0.196
ninaEneither inactivation nor afterpotential E0.192
Pi3K92ECG4141 gene product from transcript CG4141-RB0.191
CycACyclin A0.191
sesBstress-sensitive B0.189
Fs(2)KetFemale sterile (2) Ketel0.186
CG12042CG12042 gene product from transcript CG12042-RA0.184
trxtrithorax0.183
par-6CG5884 gene product from transcript CG5884-RA0.181
Rab7Rab-protein 70.181
emcextra macrochaetae0.181
alpha-AdaptinCG4260 gene product from transcript CG4260-RA0.176
pex13peroxin 130.175
pex16peroxin 160.172
wbwing blister0.172
CG11164CG11164 gene product from transcript CG11164-RA0.169
perperiod0.169
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Pfn1profilin 10.818
Gria2glutamate receptor, ionotropic, AMPA 20.789
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.761
Tnftumor necrosis factor (TNF superfamily, member 2)0.704
Hsph1heat shock 105/110 protein 10.692
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.676
Apbb1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.622
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.501
Mapk1mitogen activated protein kinase 10.500
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.452
Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.422
Capza2capping protein (actin filament) muscle Z-line, alpha 20.407
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.378
Cops7aCOP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)0.376
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.375
Canxcalnexin0.375
Actr3ARP3 actin-related protein 3 homolog (yeast)0.361
Cd4Cd4 molecule0.357
Nrxn1neurexin 10.346
Stip1stress-induced phosphoprotein 10.343
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.336
Sgtasmall glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha0.331
Lmnalamin A0.325
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.321
Rab11aRAB11a, member RAS oncogene family0.309
Gdi1GDP dissociation inhibitor 10.303
Fgfr2fibroblast growth factor receptor 20.297
Nckap1NCK-associated protein 10.294
Eef2eukaryotic translation elongation factor 20.291
Trhr2thyrotropin releasing hormone receptor 20.290
Adora3adenosine A3 receptor0.289
Ppp3cbprotein phosphatase 3, catalytic subunit, beta isoform0.282
Stxbp1syntaxin binding protein 10.277
Gria3glutamate receptor, ionotrophic, AMPA 30.277
Rhobras homolog gene family, member B0.277
Snap25synaptosomal-associated protein 250.275
Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform0.268
Ubqln1ubiquilin 10.267
Rhoaras homolog gene family, member A0.260
Hspa8heat shock protein 80.255
S100a10S100 calcium binding protein A100.255
Syngr2synaptogyrin 20.252
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.248
Rab6aRAB6A, member RAS oncogene family0.241
Chrna2cholinergic receptor, nicotinic, alpha 2 (neuronal)0.237
RragaRas-related GTP binding A0.233
Sncasynuclein, alpha (non A4 component of amyloid precursor)0.228
AktipAKT interacting protein0.228
Hckhemopoietic cell kinase0.226
Hspd1heat shock protein 1 (chaperonin)0.224
Actbactin, beta0.223
Fkbp1aFK506 binding protein 1a0.216
Adora2aadenosine A2a receptor0.215
Ptafrplatelet-activating factor receptor0.214
Nek9NIMA (never in mitosis gene a)- related kinase 90.211
Stx1asyntaxin 1A (brain)0.211
Ppm1aprotein phosphatase 1A, magnesium dependent, alpha isoform0.205
Gria1glutamate receptor, ionotropic, AMPA 10.204
Klf6Kruppel-like factor 60.202
Pip4k2bphosphatidylinositol-5-phosphate 4-kinase, type II, beta0.202
Cxcl10chemokine (C-X-C motif) ligand 100.200
Htr75-hydroxytryptamine (serotonin) receptor 70.194
Anxa5annexin A50.193
Mmp12matrix metallopeptidase 120.192
Pdcl3phosducin-like 30.192
Pdia6protein disulfide isomerase family A, member 60.192
Stx12syntaxin 120.190
Ndfip1Nedd4 family interacting protein 10.190
Glg1golgi apparatus protein 10.187
Stat6signal transducer and activator of transcription 60.187
Msmbmicroseminoprotein, beta0.185
Dlgap3discs, large (Drosophila) homolog-associated protein 30.185
Myadmmyeloid-associated differentiation marker0.184
Dnajb1DnaJ (Hsp40) homolog, subfamily B, member 10.182
Sdcbpsyndecan binding protein0.178
Ctsecathepsin E0.178
Slc12a3solute carrier family 12 (sodium/chloride transporters), member 30.177
Calrcalreticulin0.175
Col5a1collagen, type V, alpha 10.173
Rab3aRAB3A, member RAS oncogene family0.171
Rararetinoic acid receptor, alpha0.170
Rap1bRAP1B, member of RAS oncogene family0.169
Ppp2r2aprotein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform0.168
Arf4ADP-ribosylation factor 40.168
Actg1actin, gamma 10.166
Gdi2GDP dissociation inhibitor 20.165
Fkbp4FK506 binding protein 40.165
Gnai1guanine nucleotide binding protein (G protein), alpha inhibiting 10.165
Calcbcalcitonin-related polypeptide, beta0.162
Icam1intercellular adhesion molecule 10.161
Ndfip2Nedd4 family interacting protein 20.161
Grip2glutamate receptor interacting protein 20.160
Tpm3tropomyosin 3, gamma0.159
Pdia4protein disulfide isomerase family A, member 40.159
Prkcdprotein kinase C, delta0.157
Zranb2zinc finger, RAN-binding domain containing 20.155
Cd83CD83 molecule0.154
Cdk11bcyclin-dependent kinase 11B0.153
Map3k8mitogen-activated protein kinase kinase kinase 80.153
Hsp90b1heat shock protein 90, beta, member 10.152
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
TIM23Tim23p0.999
TOM22Tom22p0.997
TOM40Tom40p0.991
TOM20Tom20p0.989
PEX14Pex14p0.988
VPS28Vps28p0.987
BMH1Bmh1p0.978
TIM17Tim17p0.974
NUP116Nup116p0.974
NUP145Nup145p0.968
TOM70Tom70p0.965
VPS4Vps4p0.962
TIM44Tim44p0.959
NUP49Nup49p0.959
VPS21Vps21p0.958
PEX13Pex13p0.958
HSP82Hsp82p0.954
NUP2Nup2p0.949
ERV25Erv25p0.941
TOM5Tom5p0.940
ERP2Erp2p0.938
SEC63Sec63p0.937
NIC96Nic96p0.934
SSC1Ssc1p0.933
KAP95Kap95p0.931
TIM50Tim50p0.930
TIM54Tim54p0.930
PEX12Pex12p0.925
TIM18Tim18p0.922
NSP1Nsp1p0.920
PSE1Pse1p0.914
PEX2Pex2p0.903
PAM18Pam18p0.902
SAM35Sam35p0.898
YPT1Ypt1p0.896
SLT2Slt2p0.894
PEP3Pep3p0.892
PEX15Pex15p0.891
MIM1Mim1p0.881
COG6Cog6p0.879
VPS36Vps36p0.876
PEX5Pex5p0.876
STI1Sti1p0.872
TIM10Tim10p0.869
ATG21Atg21p0.865
APL5Apl5p0.865
BTN2Btn2p0.857
SEC62Sec62p0.849
CRM1Crm1p0.848
SLG1Slg1p0.843
ATG16Atg16p0.843
MIA40Mia40p0.840
VAM6Vam6p0.839
YPT6Ypt6p0.834
ERP5Erp5p0.826
PEX3Pex3p0.819
KAR2Kar2p0.817
SAM50Sam50p0.817
PEX10Pex10p0.817
YPT10Ypt10p0.815
CMD1Cmd1p0.813
TLG2Tlg2p0.813
SNX4Snx4p0.804
ATG7Atg7p0.798
COG5Cog5p0.797
SRP68Srp68p0.795
ALO1Alo1p0.783
MDM20Mdm20p0.778
NPR1Npr1p0.774
KAP123Kap123p0.764
VPS30Vps30p0.753
PEX6Pex6p0.750
ATG9Atg9p0.750
SRN2Srn2p0.749
PEP8Pep8p0.748
NUP120Nup120p0.746
NUP170Nup170p0.745
APM3Apm3p0.740
MGE1Mge1p0.733
LAS17Las17p0.727
LOS1Los1p0.724
SRO7Sro7p0.723
MON1Mon1p0.721
YPT31Ypt31p0.719
GLE1Gle1p0.718
NUP1Nup1p0.716
SEC4Sec4p0.711
ATG8Atg8p0.709
USA1Usa1p0.708
PEP5Pep5p0.693
SPA2Spa2p0.681
COG8Cog8p0.680
TIM13Tim13p0.674
YPT7Ypt7p0.669
SRP54Srp54p0.668
SEC66Sec66p0.665
TIM21Tim21p0.661
MDY2Mdy2p0.661
SIF2Sif2p0.654
MYO5Myo5p0.653