The network for 'regulation of apoptotic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of apoptotic process

Any process that modulates the occurrence or rate of cell death by apoptotic process.

NameDescriptionProbabilityFunc Analog Organism
hsp-1Protein HSP-10.679
egl-18Protein EGL-180.376
soc-2Protein SOC-20.294
egl-46Protein EGL-460.234
hcp-3Protein HCP-30.201
eef-1A.1Protein EEF-1A.10.190
par-5Protein PAR-50.158
F31D4.2Protein F31D4.20.124
CELE_C12D8.1Protein C12D8.10.119
lmn-1Protein LMN-10.117
pry-1Protein PRY-10.115
bar-1Protein BAR-10.115
F36D4.5Protein F36D4.50.110
eps-8Protein EPS-80.109
let-502Protein LET-5020.109
rpt-3Protein RPT-30.104
sma-6Protein SMA-60.103
mat-3Protein MAT-30.100
ceh-20Protein CEH-200.097
F36A2.13Protein F36A2.130.091
rad-26Protein RAD-260.090
nasp-1Protein NASP-10.085
F39B2.1Protein F39B2.10.084
egl-30Protein EGL-300.081
vab-3Protein VAB-30.076
pal-1Protein PAL-10.076
daf-21Protein DAF-210.074
rla-0Protein RLA-00.073
nrde-2Protein NRDE-20.072
fkh-2Protein FKH-20.071
let-60Protein LET-600.071
gld-1Protein GLD-10.070
flt-1Protein FLT-10.069
unc-52Protein UNC-520.069
fem-2Protein FEM-20.068
atg-18Protein ATG-180.067
mab-31Protein MAB-310.066
unc-73Protein UNC-730.065
F31C3.2Protein F31C3.20.064
let-756Protein LET-7560.064
dbr-1Protein DBR-10.064
imb-2Protein IMB-20.064
hum-6Protein HUM-60.063
R74.8Protein R74.80.063
crt-1Protein CRT-10.060
rpl-6Protein RPL-60.060
K10D6.4Protein K10D6.40.060
icd-1Protein ICD-10.060
egl-5Protein EGL-50.059
byn-1Protein BYN-10.057
sta-1Protein STA-10.057
htz-1Protein HTZ-10.057
CELE_Y48B6A.1Protein Y48B6A.10.056
sax-7Protein SAX-70.056
CELE_C18C4.5Protein C18C4.50.056
nhr-45Protein NHR-450.055
CELE_F14E5.2Protein F14E5.20.055
lin-1Protein LIN-10.055
unc-60Protein UNC-600.054
ant-1.1Protein ANT-1.10.054
tbb-2Protein TBB-20.054
kin-3Protein KIN-30.051
trap-4Protein TRAP-40.050
spr-4Protein SPR-40.050
vrk-1Protein VRK-10.049
rpa-1Protein RPA-10.049
C28H8.3Protein C28H8.30.048
drp-1Protein DRP-10.047
cpt-1Protein CPT-10.047
rig-6Protein RIG-60.047
ifg-1Protein IFG-10.046
tct-1Protein TCT-10.045
emo-1Protein EMO-10.045
zyg-11Protein ZYG-110.045
trim-9Protein TRIM-90.044
ceh-44Protein CEH-440.044
nhr-67Protein NHR-670.044
ostd-1Protein OSTD-10.043
ceh-38Protein CEH-380.043
CELE_T05E11.3Protein T05E11.30.042
nspa-8Protein NSPA-80.042
atp-2Protein ATP-20.042
rpl-4Protein RPL-40.042
C53B4.4Protein C53B4.40.041
unc-85Protein UNC-850.041
T23F11.1Protein T23F11.10.041
dpy-22Protein DPY-220.041
rars-1Protein RARS-10.040
pek-1Protein PEK-10.040
ceh-27Protein CEH-270.040
pmk-1Protein PMK-10.040
rpl-18Protein RPL-180.040
rnr-2Protein RNR-20.040
lin-11Protein LIN-110.040
H21P03.2Protein H21P03.20.040
osm-3Protein OSM-30.039
eya-1Protein EYA-10.038
puf-8Protein PUF-80.038
hum-5Protein HUM-50.038
ztf-7Protein ZTF-70.038
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tbx1T-box 10.997
fgf8afibroblast growth factor 8 a0.879
col2a1acollagen type II, alpha-1a0.806
shhasonic hedgehog a0.797
bmp2bbone morphogenetic protein 2b0.755
kitakit receptor a0.679
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.670
fgfr1afibroblast growth factor receptor 1a0.635
plcg1phospholipase C, gamma 10.614
ef1aelongation factor 1-alpha0.611
tbx20T-box 200.593
slc4a4asolute carrier family 4, member 4a0.581
rargaretinoic acid receptor gamma a0.577
cdh1cadherin 1, epithelial0.566
baxabcl2-associated X protein, a0.556
evx1even-skipped homeobox 10.527
tgfb3transforming growth factor, beta 30.512
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.506
sulf1sulfatase 10.505
bdnfbrain-derived neurotrophic factor0.495
alcamaactivated leukocyte cell adhesion molecule a0.491
fgfr3fibroblast growth factor receptor 30.488
sox11aSRY-box containing gene 11a0.483
nrg1neuregulin 10.472
ndr2nodal-related 20.468
fgf3fibroblast growth factor 30.453
mibmind bomb0.449
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.447
myod1myogenic differentiation 10.430
gata3GATA-binding protein 30.417
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.410
nrg2aneuregulin 2a0.404
bbc3BCL2 binding component 30.376
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.373
pdlim1PDZ and LIM domain 1 (elfin)0.370
trpm7transient receptor potential cation channel, subfamily M, member 70.370
wnt11rwingless-type MMTV integration site family, member 11, related0.370
gata5GATA-binding protein 50.359
raraaretinoic acid receptor, alpha a0.359
grnbgranulin b0.357
slc2a10solute carrier family 2 (facilitated glucose transporter), member 100.353
dlx2adistal-less homeobox gene 2a0.350
hey1hairy/enhancer-of-split related with YRPW motif 10.349
kdrlkinase insert domain receptor like0.347
spry4sprouty (Drosophila) homolog 40.343
spns2spinster homolog 2 (Drosophila)0.342
wnt9bwingless-type MMTV integration site family, member 9B0.331
mcl1amyeloid cell leukemia sequence 1a0.330
nfkbiaanuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a0.329
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.328
barhl1.2BarH-like 1.20.325
lef1lymphocyte enhancer binding factor 10.320
hspd1heat shock 60kD protein 1 (chaperonin)0.316
hand2heart and neural crest derivatives expressed transcript 20.315
sema3aasemaphorin 3aa0.314
loxl3blysyl oxidase-like 3b0.309
gnb1aguanine nucleotide binding protein (G protein), beta polypeptide 1a0.303
pea3ETS-domain transcription factor pea30.302
piwil2piwi-like 2 (Drosophila)0.300
cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.298
ascl1aachaete-scute complex-like 1a (Drosophila)0.297
pax8paired box gene 80.297
smad3aMAD homolog 3a (Drosophila)0.293
esco2establishment of cohesion 1 homolog 20.292
fzd7afrizzled homolog 7a0.287
smosmoothened homolog (Drosophila)0.281
alcambactivated leukocyte cell adhesion molecule b0.280
dusp6dual specificity phosphatase 60.279
plxnb2aplexin b2a0.276
stc1lstanniocalcin 1, like0.276
jag2jagged 20.274
maomonoamine oxidase0.274
mecp2methyl CpG binding protein 20.274
nadl1.2neural adhesion molecule L1.20.270
pax2apaired box gene 2a0.268
col14a1collagen, type XIV, alpha 10.268
ptch2patched 20.267
notch1anotch homolog 1a0.266
itgb1bintegrin, beta 1b0.260
hspa5heat shock protein 50.252
bcl2l1bcl2-like 10.252
efnb2aephrin B2a0.250
hdac1histone deacetylase 10.247
xbp1X-box binding protein 10.246
gpr126G protein-coupled receptor 1260.246
maxmyc-associated factor X0.245
tpm4tropomyosin 40.242
neo1neogenin 10.241
krit1KRIT1, ankyrin repeat containing0.235
her6hairy-related 60.234
id3inhibitor of DNA binding 30.234
slc2a12solute carrier family 2 (facilitated glucose transporter), member 120.231
tp53tumor protein p530.230
aurkbaurora kinase B0.229
rpsaribosomal protein SA0.227
hoxa4ahomeo box A4a0.226
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Akt1CG4006 gene product from transcript CG4006-RA0.997
Pi3K92ECG4141 gene product from transcript CG4141-RB0.995
PtenCG5671 gene product from transcript CG5671-RB0.978
slmbsupernumerary limbs0.975
Ras85DRas oncogene at 85D0.960
cicubitus interruptus0.951
EgfrEpidermal growth factor receptor0.949
InRInsulin-like receptor0.866
drkdownstream of receptor kinase0.845
crolcrooked legs0.801
Rac1CG2248 gene product from transcript CG2248-RA0.747
MadMothers against dpp0.724
RASSF8CG5053 gene product from transcript CG5053-RA0.681
debcldeath executioner Bcl-2 homologue0.655
phlpole hole0.622
CG11347CG11347 gene product from transcript CG11347-RE0.616
elavembryonic lethal abnormal vision0.584
Dcp-1Death caspase-10.540
S6kRPS6-p70-protein kinase0.536
jingCG9397 gene product from transcript CG9397-RI0.525
shotshort stop0.517
bab2CG9102 gene product from transcript CG9102-RA0.512
l(2)gllethal (2) giant larvae0.503
Sir2CG5216 gene product from transcript CG5216-RA0.495
Src42ASrc oncogene at 42A0.484
Nop60BNucleolar protein at 60B0.466
smt3CG4494 gene product from transcript CG4494-RA0.451
MhcMyosin heavy chain0.450
StimStromal interaction molecule0.407
SodSuperoxide dismutase0.395
RbfRetinoblastoma-family protein0.374
kibrakibra ortholog0.370
DadDaughters against dpp0.365
rapretina aberrant in pattern0.364
Hel25EHelicase at 25E0.360
LanALaminin A0.351
Aos1CG12276 gene product from transcript CG12276-RA0.338
JraJun-related antigen0.333
Myo31DFMyosin 31DF0.325
Rho1CG8416 gene product from transcript CG8416-RB0.320
Vps25Vacuolar protein sorting 250.316
emsempty spiracles0.314
Su(H)Suppressor of Hairless0.302
CycGCyclin G0.298
Gap1GTPase-activating protein 10.289
AceAcetylcholine esterase0.287
Int6Int6 homologue0.278
eIF-4aEukaryotic initiation factor 4a0.272
Hrb98DEHeterogeneous nuclear ribonucleoprotein at 98DE0.269
ik2IkappaB kinase-like 20.265
CG14869CG14869 gene product from transcript CG14869-RB0.262
Ten-mTenascin major0.261
Pk61CProtein kinase 61C0.257
LamCLamin C0.252
StamSignal transducing adaptor molecule0.249
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Dusp1dual specificity phosphatase 10.951
Cd44Cd44 molecule0.863
Dnajb1DnaJ (Hsp40) homolog, subfamily B, member 10.782
Anxa2annexin A20.752
Cdc42bpbCDC42 binding protein kinase beta (DMPK-like)0.744
Hspb1heat shock protein 10.730
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.723
Klf4Kruppel-like factor 4 (gut)0.723
Socs3suppressor of cytokine signaling 30.709
Pdia6protein disulfide isomerase family A, member 60.683
Vipvasoactive intestinal peptide0.678
Egr1early growth response 10.668
Nr4a1nuclear receptor subfamily 4, group A, member 10.666
Errfi1ERBB receptor feedback inhibitor 10.659
Junbjun B proto-oncogene0.630
Ccnd3cyclin D30.624
FosFBJ osteosarcoma oncogene0.586
Arpc1bactin related protein 2/3 complex, subunit 1B0.584
Anxa4annexin A40.575
Ripk3receptor-interacting serine-threonine kinase 30.570
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.561
Cxcr5chemokine (C-X-C motif) receptor 50.545
Mapk3mitogen activated protein kinase 30.545
Zfp36zinc finger protein 360.544
Tnfsf4tumor necrosis factor (ligand) superfamily, member 40.544
Sdcbpsyndecan binding protein0.541
Cd14CD14 molecule0.535
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.529
Csf3colony stimulating factor 3 (granulocyte)0.528
Agap3ArfGAP with GTPase domain, ankyrin repeat and PH domain 30.495
Agtr1aangiotensin II receptor, type 1a0.495
Cmtm6CKLF-like MARVEL transmembrane domain containing 60.494
Egr2early growth response 20.490
Pebp1phosphatidylethanolamine binding protein 10.471
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.458
Pla1aphospholipase A1 member A0.454
Nr4a3nuclear receptor subfamily 4, group A, member 30.453
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.447
Galr3galanin receptor 30.444
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.440
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.436
Anxa5annexin A50.434
Prlhrprolactin releasing hormone receptor0.428
Slit3slit homolog 3 (Drosophila)0.425
Grm5glutamate receptor, metabotropic 50.423
Impdh2IMP (inosine monophosphate) dehydrogenase 20.419
Prkcgprotein kinase C, gamma0.416
Itgamintegrin, alpha M0.416
Cmtm2aCKLF-like MARVEL transmembrane domain containing 2A0.409
Fgfr2fibroblast growth factor receptor 20.403
Ptger3prostaglandin E receptor 3 (subtype EP3)0.402
Foxa3forkhead box A30.401
Trib1tribbles homolog 1 (Drosophila)0.397
Stip1stress-induced phosphoprotein 10.395
Cd9CD9 molecule0.393
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.392
Arandrogen receptor0.392
Tcf21transcription factor 210.392
Aldoaaldolase A, fructose-bisphosphate0.391
Eif4ebp1eukaryotic translation initiation factor 4E binding protein 10.391
Cpxm2carboxypeptidase X (M14 family), member 20.388
Olr1078olfactory receptor 10780.387
Pkm2pyruvate kinase, muscle0.387
Hckhemopoietic cell kinase0.380
Phlda1pleckstrin homology-like domain, family A, member 10.377
S100a9S100 calcium binding protein A90.377
Id3inhibitor of DNA binding 30.375
Fgf10fibroblast growth factor 100.368
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.364
Slco2b1solute carrier organic anion transporter family, member 2b10.359
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.357
Atp5bATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.352
Lgals1lectin, galactoside-binding, soluble, 10.350
Pla2g4aphospholipase A2, group IVA (cytosolic, calcium-dependent)0.349
Fcgr3aFc fragment of IgG, low affinity IIIa, receptor0.349
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.349
Cxcl10chemokine (C-X-C motif) ligand 100.348
Jak2Janus kinase 20.347
Myo1bmyosin Ib0.347
Klf2Kruppel-like factor 2 (lung)0.344
Col8a1collagen, type VIII, alpha 10.339
Leprleptin receptor0.337
P2rx2purinergic receptor P2X, ligand-gated ion channel, 20.331
Ppbppro-platelet basic protein (chemokine (C-X-C motif) ligand 7)0.326
RGD1564327similar to integrin alpha 80.326
Cd63Cd63 molecule0.326
Gadd45agrowth arrest and DNA-damage-inducible, alpha0.326
Apoa5apolipoprotein A-V0.325
Tspotranslocator protein0.322
Cct4chaperonin containing Tcp1, subunit 4 (delta)0.322
Edn1endothelin 10.319
Ctrcchymotrypsin C (caldecrin)0.318
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.317
Il4rainterleukin 4 receptor, alpha0.314
Tgfbr2transforming growth factor, beta receptor II0.313
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism