The network for 'regulation of signaling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of signaling

Any process that modulates the frequency, rate or extent of a signaling process.

NameDescriptionProbabilityFunc Analog Organism
vab-3Protein VAB-30.957
egl-18Protein EGL-180.919
pkg-1Protein PKG-10.878
odr-3Protein ODR-30.855
pry-1Protein PRY-10.836
lag-1Protein LAG-10.749
K10D6.4Protein K10D6.40.736
sma-6Protein SMA-60.717
eor-1Protein EOR-10.713
wrm-1Protein WRM-10.675
spc-1Protein SPC-10.667
mig-5Protein MIG-50.632
che-3Protein CHE-30.626
eps-8Protein EPS-80.623
plc-1Protein PLC-10.620
goa-1Protein GOA-10.617
pxf-1Protein PXF-10.585
jnk-1Protein JNK-10.557
ptr-14Protein PTR-140.551
nhr-67Protein NHR-670.551
let-60Protein LET-600.549
itr-1Protein ITR-10.540
par-5Protein PAR-50.528
cam-1Protein CAM-10.511
egl-15Protein EGL-150.506
eef-1A.1Protein EEF-1A.10.473
che-13Protein CHE-130.472
che-2Protein CHE-20.468
abl-1Protein ABL-10.467
hlh-2Protein HLH-20.467
soc-2Protein SOC-20.458
itx-1Protein ITX-10.456
sax-3Protein SAX-30.454
magu-4Protein MAGU-40.447
sax-7Protein SAX-70.441
pha-4Protein PHA-40.436
osm-5Protein OSM-50.435
nhr-34Protein NHR-340.432
unc-9Protein UNC-90.416
unc-104Protein UNC-1040.413
npp-7Protein NPP-70.403
dpy-22Protein DPY-220.400
R151.8Protein R151.80.398
unc-32Protein UNC-320.397
pat-3Protein PAT-30.396
nhr-6Protein NHR-60.395
let-23Protein LET-230.395
unc-62Protein UNC-620.388
grk-2Protein GRK-20.379
msp-76Protein MSP-760.378
hmg-1.2Protein HMG-1.20.377
R90.1Protein R90.10.375
zyg-8Protein ZYG-80.370
hgrs-1Protein HGRS-10.368
egl-30Protein EGL-300.365
lin-25Protein LIN-250.363
daf-11Protein DAF-110.360
sgt-1Protein SGT-10.349
unc-40Protein UNC-400.348
sem-5Protein SEM-50.339
faah-1Protein FAAH-10.334
akt-1Protein AKT-10.332
pop-1Protein POP-10.326
osm-6Protein OSM-60.316
unc-79Protein UNC-790.316
T27A3.1Protein T27A3.10.315
egg-6Protein EGG-60.315
stt-3Protein STT-30.311
dpy-26Protein DPY-260.308
unc-26Protein UNC-260.306
ain-1Protein AIN-10.297
vps-33.1Protein VPS-33.10.296
alx-1Protein ALX-10.295
dnj-12Protein DNJ-120.293
let-19Protein LET-190.285
C52E12.4Protein C52E12.40.284
ceh-20Protein CEH-200.283
daf-14Protein DAF-140.283
unc-6Protein UNC-60.282
hda-3Protein HDA-30.280
egl-27Protein EGL-270.280
sur-2Protein SUR-20.277
dnc-2Protein DNC-20.277
F28E10.1Protein F28E10.10.277
ace-1Protein ACE-10.276
gdi-1Protein GDI-10.275
msp-40Protein MSP-400.273
gpb-1Protein GPB-10.268
mbk-1Protein MBK-10.265
inx-8Protein INX-80.263
ida-1Protein IDA-10.262
nipi-3Protein NIPI-30.261
unc-52Protein UNC-520.259
let-607Protein LET-6070.258
csnk-1Protein CSNK-10.258
bar-1Protein BAR-10.256
daf-19Protein DAF-190.256
crml-1Protein CRML-10.253
cid-1Protein CID-10.249
Y44E3A.6Protein Y44E3A.60.249
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
chdchordin1.000
pkd2polycystic kidney disease 20.988
fgf8afibroblast growth factor 8 a0.987
tbx1T-box 10.986
pax2apaired box gene 2a0.985
bmp2bbone morphogenetic protein 2b0.971
lft1lefty10.966
efnb2aephrin B2a0.948
shhasonic hedgehog a0.941
dlddeltaD0.940
fras1Fraser syndrome 10.939
brd4bromodomain containing 40.931
bmp4bone morphogenetic protein 40.922
flhfloating head0.919
rarabretinoic acid receptor, alpha b0.903
gli2aGLI-Kruppel family member GLI2a0.899
ntlano tail a0.885
tfap2atranscription factor AP-2 alpha0.882
fgf3fibroblast growth factor 30.874
furinafurin (paired basic amino acid cleaving enzyme) a0.866
nrp2bneuropilin 2b0.858
evx1even-skipped homeobox 10.853
bocbrother of CDO0.849
zic2azic family member 2 (odd-paired homolog, Drosophila), a0.839
dusp6dual specificity phosphatase 60.830
ascl1aachaete-scute complex-like 1a (Drosophila)0.824
eve1even-skipped-like10.821
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.808
alcambactivated leukocyte cell adhesion molecule b0.806
ventventral expressed homeobox0.805
pdgfaaplatelet-derived growth factor alpha a0.802
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.793
fbn2bfibrillin 2b0.792
bmpr1aabone morphogenetic protein receptor, type 1aa0.786
gli1GLI-Kruppel family member 10.783
dkk1bdickkopf 1b0.780
dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.776
wnt2bbwingless-type MMTV integration site family, member 2Bb0.771
bmp2abone morphogenetic protein 2a0.768
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.767
sox2SRY-box containing gene 20.756
frem3Fras1 related extracellular matrix 30.746
foxa2forkhead box A20.743
bdnfbrain-derived neurotrophic factor0.739
sox9bSRY-box containing gene 9b0.734
gscgoosecoid0.726
tal1T-cell acute lymphocytic leukemia 10.719
ptpraprotein tyrosine phosphatase, receptor type, A0.717
otpaorthopedia homolog a0.713
cebpaCCAAT/enhancer binding protein (C/EBP), alpha0.706
crabp2acellular retinoic acid binding protein 2, a0.706
bmp1abone morphogenetic protein 1a0.704
smad5MAD homolog 5 (Drosophila)0.697
bmp7abone morphogenetic protein 7a0.696
nadl1.2neural adhesion molecule L1.20.696
rag1recombination activating gene 10.694
gata5GATA-binding protein 50.689
wnt5bwingless-type MMTV integration site family, member 5b0.688
bcl2l1bcl2-like 10.684
sox19aSRY-box containing gene 19a0.683
cdh2cadherin 2, neuronal0.679
ptpn11aprotein tyrosine phosphatase, non-receptor type 11, a0.675
sox10SRY-box containing gene 100.668
chsy1chondroitin sulfate synthase 10.664
fzd5frizzled homolog 50.662
wlswntless homolog (Drosophila)0.645
bmperBMP binding endothelial regulator0.645
twist1atwist1a0.641
tbx20T-box 200.640
hoxa13bhomeo box A13b0.631
tnfrsfatumor necrosis factor receptor superfamily, member a0.627
irx3airoquois homeobox protein 3a0.627
ntn1bnetrin 1b0.609
vax1ventral anterior homeobox 10.609
sulf2sulfatase 20.606
flt4fms-related tyrosine kinase 40.604
tcf7transcription factor 7 (T-cell specific, HMG-box)0.602
jag2jagged 20.599
snai1asnail homolog 1a (Drosophila)0.593
nrg2aneuregulin 2a0.590
gli3GLI-Kruppel family member GLI30.588
fn1fibronectin 10.586
vasavasa homolog0.584
lmx1b.1LIM homeobox transcription factor 1, beta 10.578
twist3twist30.576
lhx1aLIM homeobox 1a0.565
smosmoothened homolog (Drosophila)0.561
ihhaIndian hedgehog homolog a0.560
trpm7transient receptor potential cation channel, subfamily M, member 70.556
aplnrbapelin receptor b0.554
tp53bp2tumor protein p53 binding protein, 20.552
cdiptCDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)0.550
runx2brunt-related transcription factor 2b0.550
igf1rbinsulin-like growth factor 1b receptor0.543
hmx1H6 homeo box 10.542
fgfr1bfibroblast growth factor receptor 1b0.536
per3period homolog 3 (Drosophila)0.532
junjun proto-oncogene0.530
sox9aSRY-box containing gene 9a0.529
mapk3mitogen-activated protein kinase 30.523
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
BCK1Bck1p0.987
CLA4Cla4p0.950
FAR11Far11p0.695
STE50Ste50p0.605
KSS1Kss1p0.551
AKL1Akl1p0.530
ROM2Rom2p0.530
FAR1Far1p0.513
PBS2Pbs2p0.477
RRI1Rri1p0.463
PPH21Pph21p0.455
FUS3Fus3p0.447
MSN2Msn2p0.431
SLT2Slt2p0.429
VPS21Vps21p0.406
TPK1Tpk1p0.395
SSK2Ssk2p0.351
PIK1Pik1p0.341
VPS64Vps64p0.335
SHO1Sho1p0.334
TPK2Tpk2p0.319
VPS27Vps27p0.307
SPT16Spt16p0.304
SKP1Skp1p0.300
HSP60Hsp60p0.295
CDC34Cdc34p0.292
BCY1Bcy1p0.280
RHO1Rho1p0.279
ENA5Ena5p0.278
KOG1Kog1p0.271
LSP1Lsp1p0.265
PRB1Prb1p0.248
TPS1Tps1p0.247
BCK2Bck2p0.247
SLG1Slg1p0.242
MKT1Mkt1p0.241
MON1Mon1p0.239
CRZ1Crz1p0.236
HOG1Hog1p0.222
TSA2Tsa2p0.216
DUG2Dug2p0.210
SRO7Sro7p0.209
ERP4Erp4p0.206
RAS1Ras1p0.199
CDC53Cdc53p0.197
CCS1Ccs1p0.195
SEC4Sec4p0.195
VPS30Vps30p0.191
TIF6Tif6p0.190
DID4Did4p0.188
ICE2Ice2p0.184
YGL036Whypothetical protein0.182
RTT106Rtt106p0.181
YPT1Ypt1p0.181
IRA1Ira1p0.177
STE2Ste2p0.177
BEM2Bem2p0.177
COP1Cop1p0.176
YAK1Yak1p0.176
GDI1Gdi1p0.175
GYL1Gyl1p0.175
SNF8Snf8p0.174
CDC25Cdc25p0.174
RLM1Rlm1p0.173
RUD3Rud3p0.170
OSH2Osh2p0.169
BET3Bet3p0.167
STE5Ste5p0.165
SSK22Ssk22p0.165
PTC1Ptc1p0.165
OLE1Ole1p0.165
SLM2Slm2p0.162
RIO2Rio2p0.161
INP52Inp52p0.158
STE18Ste18p0.157
YPT10Ypt10p0.154
SEC21Sec21p0.147
TRS65Trs65p0.143
RGD1Rgd1p0.143
VPS36Vps36p0.141
SIR4Sir4p0.140
CSI1Csi1p0.138
IZH4Izh4p0.136
PEX5Pex5p0.131
PMT5Pmt5p0.131
DID2Did2p0.131
YOL087Chypothetical protein0.131
PEP5Pep5p0.128
LCB4Lcb4p0.128
PEX12Pex12p0.127
CMP2Cmp2p0.125
ATG11Atg11p0.124
PEX4Pex4p0.124
NBP2Nbp2p0.123
SUB2Sub2p0.123
SSK1Ssk1p0.123
PPE1Ppe1p0.122
FUM1Fum1p0.122
SEC2Sec2p0.121
PEX10Pex10p0.119