The network for 'maintenance of location in cell' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

maintenance of location in cell

Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.

NameDescriptionProbabilityFunc Analog Organism
ubxn-4Protein UBXN-40.291
knl-1Protein KNL-10.267
him-10Protein HIM-100.242
acs-4Protein ACS-40.238
hcp-2Protein HCP-20.208
mcm-7Protein MCM-70.206
rab-1Protein RAB-10.177
hcp-1Protein HCP-10.173
mig-6Protein MIG-60.140
daf-21Protein DAF-210.139
spk-1Protein SPK-10.133
lmn-1Protein LMN-10.133
klp-19Protein KLP-190.120
spd-5Protein SPD-50.106
unc-70Protein UNC-700.105
cup-2Protein CUP-20.097
flh-1Protein FLH-10.085
prp-3Protein PRP-30.073
hsp-1Protein HSP-10.073
eat-6Protein EAT-60.070
let-2Protein LET-20.067
aspm-1Protein ASPM-10.065
air-2Protein AIR-20.065
ima-3Protein IMA-30.056
lap-2Protein LAP-20.054
bub-1Protein BUB-10.050
tba-2Protein TBA-20.045
hpo-9Protein HPO-90.044
hmg-1.2Protein HMG-1.20.041
F33H2.5Protein F33H2.50.040
gpr-1Protein GPR-10.039
nmy-2Protein NMY-20.038
hcp-4Protein HCP-40.038
W09D10.1Protein W09D10.10.035
stam-1Protein STAM-10.035
ztf-7Protein ZTF-70.035
hum-2Protein HUM-20.035
cyk-4Protein CYK-40.034
lin-13Protein LIN-130.034
sca-1Protein SCA-10.033
rod-1Protein ROD-10.033
sas-5Protein SAS-50.033
drh-3Protein DRH-30.032
fzy-1Protein FZY-10.032
mut-16Protein MUT-160.031
lin-5Protein LIN-50.031
cin-4Protein CIN-40.031
pkg-1Protein PKG-10.031
F56D2.6Protein F56D2.60.029
fln-2Protein FLN-20.029
CELE_F19F10.9Protein F19F10.90.029
zyg-9Protein ZYG-90.028
mus-101Protein MUS-1010.028
cki-2Protein CKI-20.028
T24H10.1Protein T24H10.10.027
yif-1Protein YIF-10.027
Y47D3A.29Protein Y47D3A.290.027
dcr-1Protein DCR-10.027
atl-1Protein ATL-10.026
C28H8.4Protein C28H8.40.026
lst-3Protein LST-30.026
chc-1Protein CHC-10.026
plc-1Protein PLC-10.026
rpn-10Protein RPN-100.025
attf-2Protein ATTF-20.025
spd-2Protein SPD-20.025
rpn-1Protein RPN-10.025
bmk-1Protein BMK-10.025
ada-2Protein ADA-20.025
T07C4.10Protein T07C4.100.024
tbb-1Protein TBB-10.024
cpg-3Protein CPG-30.023
zfp-1Protein ZFP-10.022
H40L08.1Protein H40L08.10.022
T19H12.2Protein T19H12.20.022
cpg-1Protein CPG-10.019
him-1Protein HIM-10.019
csn-3Protein CSN-30.018
let-502Protein LET-5020.018
nkcc-1Protein NKCC-10.018
pdi-3Protein PDI-30.018
CELE_R06A4.2Protein R06A4.20.017
R11A8.7Protein R11A8.70.017
smc-3Protein SMC-30.017
F10C2.4Protein F10C2.40.017
dsh-2Protein DSH-20.017
pod-1Protein POD-10.017
gpd-4Protein GPD-40.016
eor-2Protein EOR-20.016
H11E01.3Protein H11E01.30.016
mcm-3Protein MCM-30.016
rbc-1Protein RBC-10.016
dnj-12Protein DNJ-120.016
pde-2Protein PDE-20.016
icp-1Protein ICP-10.015
pcn-1Protein PCN-10.015
let-607Protein LET-6070.015
F10D7.5Protein F10D7.50.015
F15G9.1Protein F15G9.10.015
apl-1Protein APL-10.015
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CycBCyclin B0.743
ana3anastral spindle 30.619
cmetCENP-meta0.509
cnocanoe0.480
ncdnon-claret disjunctional0.400
pavpavarotti0.338
hydhyperplastic discs0.321
ctpcut up0.313
ChcClathrin heavy chain0.292
GugGrunge0.270
spd-2spindle defective 20.258
Spc105RSpc105-related0.257
aopanterior open0.231
sqhspaghetti squash0.231
chicchickadee0.214
MybMyb oncogene-like0.208
CG4680CG4680 gene product from transcript CG4680-RA0.187
aspabnormal spindle0.154
chbchromosome bows0.136
MoeMoesin0.134
armarmadillo0.129
Nek2CG17256 gene product from transcript CG17256-RA0.126
AblAbl tyrosine kinase0.126
chicoCG5686 gene product from transcript CG5686-RB0.122
UBL3CG9038 gene product from transcript CG9038-RC0.120
aslasterless0.119
cicubitus interruptus0.116
fufused0.111
rokRho-kinase0.106
MerMerlin0.101
mit(1)15mitotic 150.096
coscosta0.096
tumtumbleweed0.095
Pp2A-29BProtein phosphatase 2A at 29B0.094
ensensconsin0.089
gekgenghis khan0.087
poloCG12306 gene product from transcript CG12306-RA0.085
Unc-76CG3981 gene product from transcript CG3981-RB0.085
dallydivision abnormally delayed0.083
fzyfizzy0.078
Poc1Proteome of centrioles 10.071
ph-ppolyhomeotic proximal0.071
crbcrumbs0.068
sleslender lobes0.068
thrthree rows0.065
Cep135CG17081 gene product from transcript CG17081-RB0.065
gishgilgamesh0.065
twetwine0.064
mrmorula0.064
Dlc90FDynein light chain 90F0.064
CHMP2BCharged multivesicular body protein 2b0.062
Src64BSrc oncogene at 64B0.061
trbltribbles0.058
Sgt1CG9617 gene product from transcript CG9617-RA0.056
katanin-60katanin 600.055
shrbshrub0.053
CycB3Cyclin B30.047
HcfHost cell factor0.047
Spc25CG7242 gene product from transcript CG7242-RA0.046
Rab11Rab-protein 110.043
auxauxillin0.041
Rho1CG8416 gene product from transcript CG8416-RB0.040
diadiaphanous0.038
CG4771CG4771 gene product from transcript CG4771-RA0.038
Tip60CG6121 gene product from transcript CG6121-RA0.038
Sin3ACG8815 gene product from transcript CG8815-RC0.037
CG5690CG5690 gene product from transcript CG5690-RA0.037
eglegalitarian0.037
pUf68poly U binding factor 68kD0.037
Bx42CG8264 gene product from transcript CG8264-RA0.036
ttvtout-velu0.036
pcxpecanex0.035
wispwispy0.035
gammaTub37Cgamma-Tubulin at 37C0.035
Cct1CTP:phosphocholine cytidylyltransferase 10.034
swaswallow0.034
marsCG17064 gene product from transcript CG17064-RB0.034
StimStromal interaction molecule0.034
CG10754CG10754 gene product from transcript CG10754-RA0.034
smosmoothened0.034
bazbazooka0.032
DgDystroglycan0.031
CG11006CG11006 gene product from transcript CG11006-RC0.031
lkb1CG9374 gene product from transcript CG9374-RJ0.031
OteOtefin0.030
DrefDNA replication-related element factor0.030
RicRas which interacts with Calmodulin0.030
CG8232CG8232 gene product from transcript CG8232-RA0.029
Dsor1Downstream of raf10.028
RYBPRing and YY1 Binding Protein0.028
Klp10ACG1453 gene product from transcript CG1453-RA0.028
maskmultiple ankyrin repeats single KH domain0.028
cutletCG33122 gene product from transcript CG33122-RA0.027
cnkconnector enhancer of ksr0.026
tldtolloid0.026
zwilchCG18729 gene product from transcript CG18729-RA0.026
Vps4Vacuolar protein sorting 40.026
mei-P26CG12218 gene product from transcript CG12218-RA0.026
Klp61FKinesin-like protein at 61F0.026
sas-6spindle assembly abnormal 60.025
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
GSK3Bglycogen synthase kinase 3 beta0.952
PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.943
BUB1budding uninhibited by benzimidazoles 1 homolog (yeast)0.913
CENPEcentromere protein E, 312kDa0.882
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.838
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.786
ZWINTZW10 interactor0.742
NCAPD2non-SMC condensin I complex, subunit D20.731
NUF2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.688
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.652
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.609
PSMC4proteasome (prosome, macropain) 26S subunit, ATPase, 40.603
RB1retinoblastoma 10.574
VCLvinculin0.562
FLNAfilamin A, alpha0.551
ZYXzyxin0.515
KIF23kinesin family member 230.506
RACGAP1Rac GTPase activating protein 10.505
CKAP5cytoskeleton associated protein 50.491
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.484
TAF5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa0.452
NDC80NDC80 homolog, kinetochore complex component (S. cerevisiae)0.447
SUN1Sad1 and UNC84 domain containing 10.421
AURKAaurora kinase A0.412
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.406
KPNA2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.401
CDC25Bcell division cycle 25 homolog B (S. pombe)0.392
NCAPHnon-SMC condensin I complex, subunit H0.378
PSAPprosaposin0.355
SYNE2spectrin repeat containing, nuclear envelope 20.352
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.346
NPLOC4nuclear protein localization 4 homolog (S. cerevisiae)0.331
CBX5chromobox homolog 50.326
CEP55centrosomal protein 55kDa0.323
ZMYND11zinc finger, MYND-type containing 110.315
TTKTTK protein kinase0.312
TNFRSF6Btumor necrosis factor receptor superfamily, member 6b, decoy0.311
ACTN1actinin, alpha 10.304
PSEN1presenilin 10.304
ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila)0.299
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.291
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.285
RHOAras homolog gene family, member A0.272
SMAD2SMAD family member 20.261
FKBP1AFK506 binding protein 1A, 12kDa0.261
CDCA8cell division cycle associated 80.252
SMAD4SMAD family member 40.244
OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF0.241
CKS2CDC28 protein kinase regulatory subunit 20.237
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.236
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.233
MYH9myosin, heavy chain 9, non-muscle0.229
GGA2golgi-associated, gamma adaptin ear containing, ARF binding protein 20.225
ZFYVE9zinc finger, FYVE domain containing 90.215
CDC20cell division cycle 20 homolog (S. cerevisiae)0.215
CENPFcentromere protein F, 350/400kDa (mitosin)0.212
SPC25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.208
DNMT1DNA (cytosine-5-)-methyltransferase 10.196
PRC1protein regulator of cytokinesis 10.192
NSL1NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)0.190
ERBB2IPerbb2 interacting protein0.187
AKT1v-akt murine thymoma viral oncogene homolog 10.179
APCadenomatous polyposis coli0.177
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.174
HIPK3homeodomain interacting protein kinase 30.173
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.168
PEX5peroxisomal biogenesis factor 50.162
HMMRhyaluronan-mediated motility receptor (RHAMM)0.161
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.161
MDM4Mdm4 p53 binding protein homolog (mouse)0.155
KIF14kinesin family member 140.153
MKI67antigen identified by monoclonal antibody Ki-670.151
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.149
ANLNanillin, actin binding protein0.148
SOCS5suppressor of cytokine signaling 50.147
SYNRGsynergin, gamma0.144
MAP4K3mitogen-activated protein kinase kinase kinase kinase 30.143
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.141
CHUKconserved helix-loop-helix ubiquitous kinase0.134
CREBBPCREB binding protein0.133
DLGAP5discs, large (Drosophila) homolog-associated protein 50.133
NEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like0.124
PSEN2presenilin 2 (Alzheimer disease 4)0.123
KIF20Akinesin family member 20A0.121
BBS2Bardet-Biedl syndrome 20.119
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.119
DMDdystrophin0.112
MIS12MIS12, MIND kinetochore complex component, homolog (S. pombe)0.111
SEC24BSEC24 family, member B (S. cerevisiae)0.104
MSNmoesin0.104
USP8ubiquitin specific peptidase 80.103
SGCDsarcoglycan, delta (35kDa dystrophin-associated glycoprotein)0.103
DSN1DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)0.103
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.101
EHD1EH-domain containing 10.099
TPX2TPX2, microtubule-associated, homolog (Xenopus laevis)0.096
CHMP1Achromatin modifying protein 1A0.096
VHLvon Hippel-Lindau tumor suppressor0.095
PCM1pericentriolar material 10.094
TBCDtubulin folding cofactor D0.091
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ctnnb1catenin (cadherin associated protein), beta 10.576
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.513
Smad4MAD homolog 4 (Drosophila)0.504
Trp53transformation related protein 530.315
Htthuntingtin0.273
Tgfbr2transforming growth factor, beta receptor II0.244
Cep55centrosomal protein 550.223
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.183
Macf1microtubule-actin crosslinking factor 10.165
Kif4kinesin family member 40.154
Fgfr1fibroblast growth factor receptor 10.119
Hmmrhyaluronan mediated motility receptor (RHAMM)0.112
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.111
Mis18bp1MIS18 binding protein 10.109
Kif20akinesin family member 20A0.108
Apcadenomatosis polyposis coli0.105
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.100
Incenpinner centromere protein0.093
Atp7aATPase, Cu++ transporting, alpha polypeptide0.088
Cltcclathrin, heavy polypeptide (Hc)0.082
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.082
Plk1polo-like kinase 1 (Drosophila)0.082
Bbs2Bardet-Biedl syndrome 2 (human)0.082
Kif2ckinesin family member 2C0.079
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.073
Tln1talin 10.067
Gsk3bglycogen synthase kinase 3 beta0.067
SkilSKI-like0.067
Trim3tripartite motif-containing 30.059
Rararetinoic acid receptor, alpha0.059
Ap2b1adaptor-related protein complex 2, beta 1 subunit0.059
Fgd1FYVE, RhoGEF and PH domain containing 10.058
Tjp1tight junction protein 10.058
Ncaphnon-SMC condensin I complex, subunit H0.057
Cdc25ccell division cycle 25 homolog C (S. pombe)0.056
Usp9xubiquitin specific peptidase 9, X chromosome0.056
H2afxH2A histone family, member X0.054
Rargretinoic acid receptor, gamma0.054
Cep290centrosomal protein 2900.053
Kiss1KiSS-1 metastasis-suppressor0.053
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.051
Iqgap3IQ motif containing GTPase activating protein 30.051
Fshrfollicle stimulating hormone receptor0.050
Spag5sperm associated antigen 50.050
Cdkn3cyclin-dependent kinase inhibitor 30.049
Cenpfcentromere protein F0.049
Spna2spectrin alpha 20.047
D2Ertd750eDNA segment, Chr 2, ERATO Doi 750, expressed0.047
Esr1estrogen receptor 1 (alpha)0.046
Aspmasp (abnormal spindle)-like, microcephaly associated (Drosophila)0.046
Ndc80NDC80 homolog, kinetochore complex component (S. cerevisiae)0.046
Invsinversin0.045
Vclvinculin0.045
Ckap2cytoskeleton associated protein 20.044
Dmddystrophin, muscular dystrophy0.043
Spnb2spectrin beta 20.043
Trove2TROVE domain family, member 20.043
Aurkbaurora kinase B0.040
Lcklymphocyte protein tyrosine kinase0.040
Thrathyroid hormone receptor alpha0.039
Kif11kinesin family member 110.039
Ptenphosphatase and tensin homolog0.038
Ctnna1catenin (cadherin associated protein), alpha 10.037
Brca1breast cancer 10.037
Clip1CAP-GLY domain containing linker protein 10.035
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.035
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.035
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.034
StilScl/Tal1 interrupting locus0.034
Notch2Notch gene homolog 2 (Drosophila)0.034
Strn3striatin, calmodulin binding protein 30.034
Kif22kinesin family member 220.032
Top2atopoisomerase (DNA) II alpha0.032
Bub1budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)0.032
Glg1golgi apparatus protein 10.032
Ythdf1YTH domain family 10.032
Foxc1forkhead box C10.031
Apoeapolipoprotein E0.031
Ikbkbinhibitor of kappaB kinase beta0.030
Ncoa1nuclear receptor coactivator 10.030
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.030
FybFYN binding protein0.029
Ccna2cyclin A20.029
Thrbthyroid hormone receptor beta0.029
Hsp90b1heat shock protein 90, beta (Grp94), member 10.029
Fbn1fibrillin 10.028
Capzbcapping protein (actin filament) muscle Z-line, beta0.028
Ccnfcyclin F0.027
Gnrh1gonadotropin releasing hormone 10.027
Sdcbpsyndecan binding protein0.026
Kif5bkinesin family member 5B0.026
Cttncortactin0.026
Apoa1apolipoprotein A-I0.026
Rock1Rho-associated coiled-coil containing protein kinase 10.026
Ube2cubiquitin-conjugating enzyme E2C0.026
Diap3diaphanous homolog 3 (Drosophila)0.026
Ece1endothelin converting enzyme 10.026
Nek2NIMA (never in mitosis gene a)-related expressed kinase 20.025
Stk3serine/threonine kinase 3 (Ste20, yeast homolog)0.025
Anapc2anaphase promoting complex subunit 20.025
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
ASK1Ask1p0.984
DAD4Dad4p0.884
SPC34Spc34p0.874
DAM1Dam1p0.847
ERP5Erp5p0.846
DUO1Duo1p0.800
DAD2Dad2p0.776
HSK3Hsk3p0.478
CLB6Clb6p0.470
SWE1Swe1p0.407
CKS1Cks1p0.356
SNF7Snf7p0.353
SPC19Spc19p0.337
DAD1Dad1p0.334
DSN1Dsn1p0.323
HOC1Hoc1p0.302
MDM10Mdm10p0.282
ERP2Erp2p0.280
CDC24Cdc24p0.271
OKP1Okp1p0.229
VPS5Vps5p0.219
CTF3Ctf3p0.197
VPS34Vps34p0.188
CLB4Clb4p0.181
VPS17Vps17p0.180
DAD3Dad3p0.178
PEP8Pep8p0.174
SPC98Spc98p0.172
VPS35Vps35p0.149
CDC28Cdc28p0.147
SPC29Spc29p0.145
TID3Tid3p0.143
SCJ1Scj1p0.142
VPS74Vps74p0.138
RER1Rer1p0.130
VPS38Vps38p0.127
FCJ1Fcj1p0.120
KIN2Kin2p0.117
CPT1Cpt1p0.117
SLI15Sli15p0.115
RNR2Rnr2p0.111
VPS28Vps28p0.107
VAC8Vac8p0.105
UPS1Ups1p0.105
CHL4Chl4p0.105
ATG21Atg21p0.103
VID22Vid22p0.102
MTW1Mtw1p0.101
CSE4Cse4p0.100
ERD1Erd1p0.099
NAB3Nab3p0.097
HDA2Hda2p0.097
NDD1Ndd1p0.095
SLK19Slk19p0.094
MEP2Mep2p0.094
NRM1Nrm1p0.090
FMP30Fmp30p0.088
COQ5Coq5p0.087
MCM21Mcm21p0.085
TED1Ted1p0.085
IML3Iml3p0.085
YCK1Yck1p0.084
PMR1Pmr1p0.083
OST2Ost2p0.082
BIK1Bik1p0.079
YPL014Whypothetical protein0.077
MDM32Mdm32p0.076
TUB3Tub3p0.076
MMM1Mmm1p0.075
CLN1Cln1p0.073
TLG2Tlg2p0.073
CTF19Ctf19p0.073
MDM20Mdm20p0.072
VPS30Vps30p0.072
SEC11Sec11p0.070
ATG17Atg17p0.070
ALG14Alg14p0.066
YBR096Whypothetical protein0.065
RHO1Rho1p0.063
ERP6Erp6p0.063
STE4Ste4p0.063
FIN1Fin1p0.061
OST5Ost5p0.061
SNF8Snf8p0.060
SHE1She1p0.060
MGE1Mge1p0.059
PTC3Ptc3p0.059
DEF1Def1p0.059
DNM1Dnm1p0.059
NUF2Nuf2p0.058
CSF1Csf1p0.057
CIN2Cin2p0.056
NSL1Nsl1p0.056
MIF2Mif2p0.056
SFB2Sfb2p0.056
IST1Ist1p0.055
CDC5Cdc5p0.055
SAM35Sam35p0.054
YMR1Ymr1p0.054
YCK3Yck3p0.054