The network for 'tissue morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

tissue morphogenesis

The process in which the anatomical structures of a tissue are generated and organized.

NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.934
hlh-1Protein HLH-10.889
pha-4Protein PHA-40.879
pal-1Protein PAL-10.812
atn-1Protein ATN-10.798
nhr-67Protein NHR-670.641
hlh-2Protein HLH-20.640
fkh-2Protein FKH-20.628
egl-46Protein EGL-460.627
cam-1Protein CAM-10.607
bar-1Protein BAR-10.558
zip-7Protein ZIP-70.490
sma-6Protein SMA-60.479
epi-1Protein EPI-10.476
lin-36Protein LIN-360.446
ten-1Protein TEN-10.440
elt-6Protein ELT-60.416
unc-73Protein UNC-730.390
egl-15Protein EGL-150.376
let-60Protein LET-600.371
unc-52Protein UNC-520.362
lin-12Protein LIN-120.325
egl-13Protein EGL-130.312
sem-5Protein SEM-50.283
osm-3Protein OSM-30.277
aspm-1Protein ASPM-10.263
irx-1Protein IRX-10.255
sel-12Protein SEL-120.254
lsy-2Protein LSY-20.252
egl-27Protein EGL-270.251
F55F8.9Protein F55F8.90.250
inx-13Protein INX-130.240
cwn-1Protein CWN-10.235
lin-17Protein LIN-170.233
myo-3Protein MYO-30.210
eya-1Protein EYA-10.207
unc-53Protein UNC-530.207
kal-1Protein KAL-10.205
pes-1Protein PES-10.201
sur-2Protein SUR-20.197
ina-1Protein INA-10.195
mig-6Protein MIG-60.190
rig-6Protein RIG-60.190
tbx-9Protein TBX-90.184
pop-1Protein POP-10.183
apl-1Protein APL-10.180
soc-2Protein SOC-20.178
che-13Protein CHE-130.178
R10E12.2Protein R10E12.20.174
lag-1Protein LAG-10.173
glp-1Protein GLP-10.172
tbx-8Protein TBX-80.172
gpr-1Protein GPR-10.171
sdn-1Protein SDN-10.168
hmg-1.2Protein HMG-1.20.160
ceh-27Protein CEH-270.156
egl-38Protein EGL-380.151
unc-6Protein UNC-60.147
C06G1.5Protein C06G1.50.146
egl-44Protein EGL-440.145
imb-2Protein IMB-20.141
tmc-2Protein TMC-20.139
osm-5Protein OSM-50.137
acs-4Protein ACS-40.136
let-607Protein LET-6070.134
unc-87Protein UNC-870.133
nhr-25Protein NHR-250.132
wrm-1Protein WRM-10.132
F43D9.1Protein F43D9.10.131
flt-1Protein FLT-10.128
vab-3Protein VAB-30.127
cdf-1Protein CDF-10.125
alp-1Protein ALP-10.124
hnd-1Protein HND-10.123
smp-1Protein SMP-10.123
hlh-14Protein HLH-140.121
goa-1Protein GOA-10.119
arl-13Protein ARL-130.118
hbl-1Protein HBL-10.117
M02D8.1Protein M02D8.10.113
madf-5Protein MADF-50.111
unc-37Protein UNC-370.110
mab-5Protein MAB-50.109
Y82E9BR.13Protein Y82E9BR.130.108
unc-130Protein UNC-1300.107
unc-98Protein UNC-980.103
lin-3Protein LIN-30.103
sfrp-1Protein SFRP-10.102
unc-83Protein UNC-830.101
pax-3Protein PAX-30.100
lev-11Protein LEV-110.099
lin-29Protein LIN-290.099
igcm-3Protein IGCM-30.098
syg-2Protein SYG-20.098
pat-12Protein PAT-120.098
T28F4.1Protein T28F4.10.096
ain-1Protein AIN-10.096
C54E4.2Protein C54E4.20.095
gex-2Protein GEX-20.094
igcm-4Protein IGCM-40.094
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Rac1CG2248 gene product from transcript CG2248-RA1.000
aPKCatypical protein kinase C0.999
EgfrEpidermal growth factor receptor0.999
G-oalpha47AG protein oalpha 47A0.997
emcextra macrochaetae0.995
Akt1CG4006 gene product from transcript CG4006-RA0.994
svpseven up0.993
fz2frizzled 20.993
AtpalphaNa pump alpha subunit0.993
stumpsCG31317 gene product from transcript CG31317-RC0.993
E(spl)Enhancer of split0.990
Rho1CG8416 gene product from transcript CG8416-RB0.988
ShcSHC-adaptor protein0.986
Cdc42CG12530 gene product from transcript CG12530-RA0.985
EcREcdysone receptor0.984
Nrx-IVNeurexin IV0.983
DadDaughters against dpp0.983
salmspalt major0.982
eyaeyes absent0.981
McrMacroglobulin complement-related0.981
rawCG12437 gene product from transcript CG12437-RB0.980
BicDBicaudal D0.979
l(2)gllethal (2) giant larvae0.977
Src42ASrc oncogene at 42A0.974
par-1CG8201 gene product from transcript CG8201-RA0.972
nkdnaked cuticle0.972
PknProtein kinase related to protein kinase N0.971
rheaCG6831 gene product from transcript CG6831-RA0.967
Fmr1CG6203 gene product from transcript CG6203-RC0.961
slp1sloppy paired 10.952
cv-ccrossveinless c0.951
cicubitus interruptus0.941
RalaRas-related protein0.941
phlpole hole0.940
iHoginterference Hedgehog0.937
JraJun-related antigen0.936
Ras85DRas oncogene at 85D0.935
fkhfork head0.922
alpha-AdaptinCG4260 gene product from transcript CG4260-RA0.921
VangVan Gogh0.916
vvlventral veins lacking0.916
stanstarry night0.905
p120ctnAdherens junction protein p1200.900
numbCG3779 gene product from transcript CG3779-RB0.899
trioCG18214 gene product from transcript CG18214-RA0.897
snssticks and stones0.895
TSG101tumor suppressor protein 1010.884
CycACyclin A0.883
Rab11Rab-protein 110.872
mewmultiple edematous wings0.870
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor1.000
ESR1estrogen receptor 11.000
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)1.000
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.999
SMAD3SMAD family member 30.998
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.998
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.998
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.995
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.990
FN1fibronectin 10.989
CREBBPCREB binding protein0.988
THBS1thrombospondin 10.986
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.983
FLNAfilamin A, alpha0.982
MDM2Mdm2 p53 binding protein homolog (mouse)0.981
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.977
PRKCZprotein kinase C, zeta0.973
FGFR2fibroblast growth factor receptor 20.970
JAG1jagged 10.967
SMAD2SMAD family member 20.963
TP53tumor protein p530.960
PTK2PTK2 protein tyrosine kinase 20.952
TIMP3TIMP metallopeptidase inhibitor 30.950
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.948
TP63tumor protein p630.947
APCadenomatous polyposis coli0.946
COL4A1collagen, type IV, alpha 10.940
EPAS1endothelial PAS domain protein 10.939
ACTR3ARP3 actin-related protein 3 homolog (yeast)0.930
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.919
COL1A1collagen, type I, alpha 10.917
RUNX1runt-related transcription factor 10.913
COL4A2collagen, type IV, alpha 20.911
CASKcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.911
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.907
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.902
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.902
ERBB2IPerbb2 interacting protein0.901
GRB7growth factor receptor-bound protein 70.869
EP300E1A binding protein p3000.847
TPM1tropomyosin 1 (alpha)0.839
SIN3ASIN3 homolog A, transcription regulator (yeast)0.824
NOTCH1notch 10.817
GSK3Bglycogen synthase kinase 3 beta0.811
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.799
CTGFconnective tissue growth factor0.776
KCNJ4potassium inwardly-rectifying channel, subfamily J, member 40.768
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.767
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.758
NRP1neuropilin 10.750
NOTCH3notch 30.749
RHOAras homolog gene family, member A0.745
AKT1v-akt murine thymoma viral oncogene homolog 10.744
SOX2SRY (sex determining region Y)-box 20.742
SHC1SHC (Src homology 2 domain containing) transforming protein 10.739
FHL2four and a half LIM domains 20.732
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.715
SP1Sp1 transcription factor0.702
PTPN11protein tyrosine phosphatase, non-receptor type 110.702
SEC23ASec23 homolog A (S. cerevisiae)0.701
MYH9myosin, heavy chain 9, non-muscle0.699
COL5A1collagen, type V, alpha 10.690
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.682
COL1A2collagen, type I, alpha 20.668
PBX1pre-B-cell leukemia homeobox 10.665
FBLN1fibulin 10.663
MMP14matrix metallopeptidase 14 (membrane-inserted)0.654
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.646
RASA1RAS p21 protein activator (GTPase activating protein) 10.643
PFN1profilin 10.643
SKILSKI-like oncogene0.643
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.639
IGFBP5insulin-like growth factor binding protein 50.633
CDH3cadherin 3, type 1, P-cadherin (placental)0.629
BCORBCL6 corepressor0.627
FGF1fibroblast growth factor 1 (acidic)0.621
NCOR1nuclear receptor corepressor 10.620
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.618
TLE1transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)0.617
DLG1discs, large homolog 1 (Drosophila)0.607
SMAD7SMAD family member 70.593
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.591
METmet proto-oncogene (hepatocyte growth factor receptor)0.591
COL3A1collagen, type III, alpha 10.571
HIPK2homeodomain interacting protein kinase 20.569
RXRAretinoid X receptor, alpha0.568
TRIM63tripartite motif containing 630.564
NCOR2nuclear receptor corepressor 20.562
NR4A1nuclear receptor subfamily 4, group A, member 10.549
TNNC1troponin C type 1 (slow)0.543
EGR1early growth response 10.540
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.539
BMPR1Abone morphogenetic protein receptor, type IA0.538
FOXA2forkhead box A20.537
VEGFAvascular endothelial growth factor A0.534
HOXB5homeobox B50.533
TP53BP2tumor protein p53 binding protein, 20.533
TAL1T-cell acute lymphocytic leukemia 10.531
TGFB2transforming growth factor, beta 20.523
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.516
Ankrd1ankyrin repeat domain 1 (cardiac muscle)0.506
Acvr1activin A receptor, type I0.402
Actc1actin, alpha, cardiac muscle 10.340
Syt4synaptotagmin IV0.327
Prrx1paired related homeobox 10.308
Stat5bsignal transducer and activator of transcription 5B0.285
Acta2smooth muscle alpha-actin0.273
Scnn1gsodium channel, nonvoltage-gated 1, gamma0.255
Baiap2BAI1-associated protein 20.241
Nfianuclear factor I/A0.239
Robo1roundabout homolog 1 (Drosophila)0.235
Fgfr2fibroblast growth factor receptor 20.234
Foxd3forkhead box D30.198
Col12a1collagen, type XII, alpha 10.198
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.177
Tgfbr3transforming growth factor, beta receptor III0.176
Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.173
Npr3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)0.173
Tnctenascin C0.165
Lamc1laminin, gamma 10.161
Metmet proto-oncogene0.159
Twist2twist homolog 2 (Drosophila)0.155
Lims1LIM and senescent cell antigen-like domains 10.155
Igfbp5insulin-like growth factor binding protein 50.154
Il1r1interleukin 1 receptor, type I0.148
Agtr1aangiotensin II receptor, type 1a0.147
Ednrbendothelin receptor type B0.145
Ube2l3ubiquitin-conjugating enzyme E2L 30.145
Bcl2B-cell CLL/lymphoma 20.140
Klk1lkallikrein 1-like peptidase0.140
GperG protein-coupled estrogen receptor 10.135
Clcnkbchloride channel Kb0.132
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.119
Foxe3forkhead box E30.107
Irs1insulin receptor substrate 10.104
Arnt2aryl hydrocarbon receptor nuclear translocator 20.102
Mycsmyc-like oncogene, s-myc protein0.101
Cmtm6CKLF-like MARVEL transmembrane domain containing 60.101
Nfibnuclear factor I/B0.101
Dab2disabled homolog 2 (Drosophila)0.101
Smad7SMAD family member 70.098
Nek9NIMA (never in mitosis gene a)- related kinase 90.096
Itpr2inositol 1,4,5-triphosphate receptor, type 20.095
Myh9myosin, heavy chain 9, non-muscle0.093
Myh6myosin, heavy chain 6, cardiac muscle, alpha0.091
Reg3aregenerating islet-derived 3 alpha0.089
Myh7myosin, heavy chain 7, cardiac muscle, beta0.089
Dchs1dachsous 1 (Drosophila)0.089
MosMoloney sarcoma oncogene0.088
Sstr5somatostatin receptor 50.087
Nppcnatriuretic peptide precursor C0.084
Fat2FAT tumor suppressor homolog 2 (Drosophila)0.083
Efna5ephrin A50.083
Lig3ligase III, DNA, ATP-dependent0.082
Foxs1forkhead box S10.082
Slc12a4solute carrier family 12 (potassium/chloride transporters), member 40.079
Htr5b5-hydroxytryptamine (serotonin) receptor 5B0.078
Fgfr1Fibroblast growth factor receptor 10.078
Sema3asema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A0.076
Tgfb3transforming growth factor, beta 30.075
Hoxc4homeo box C40.075
Prkchprotein kinase C, eta0.073
Casq2calsequestrin 2 (cardiac muscle)0.072
Epha8Eph receptor A80.069
Tcfe2atranscription factor E2a0.068
Shox2short stature homeobox 20.067
Pde4bphosphodiesterase 4B, cAMP specific0.066
Capn6calpain 60.065
Slc20a2solute carrier family 20 (phosphate transporter), member 20.065
Prkar2aprotein kinase, cAMP dependent regulatory, type II alpha0.064
Nr2f2nuclear receptor subfamily 2, group F, member 20.064
Irx4iroquois homeobox 40.064
Tubb5tubulin, beta 50.062
Hoxb7homeo box B70.061
Agtr2angiotensin II receptor, type 20.057
Adra2badrenergic, alpha-2B-, receptor0.057
Klk1c10l2kallikrein 1-related peptidase c10-like 20.057
Sardhsarcosine dehydrogenase0.056
Pax8paired box 80.056
Chrngcholinergic receptor, nicotinic, gamma0.055
Flt1FMS-related tyrosine kinase 10.054
Arf1ADP-ribosylation factor 10.053
Vom2r44vomeronasal 2 receptor 440.053
Grb2growth factor receptor bound protein 20.053
Atp12aATPase, H+/K+ transporting, nongastric, alpha polypeptide0.053
Arntaryl hydrocarbon receptor nuclear translocator0.052
Tcf4transcription factor 40.052
Gata6GATA binding protein 60.052
Creb1cAMP responsive element binding protein 10.051
Pou3f2POU class 3 homeobox 20.050
Csnk1g1casein kinase 1, gamma 10.049
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.049
Chiachitinase, acidic0.048
Ap2m1adaptor-related protein complex 2, mu 1 subunit0.048
Tpm3tropomyosin 3, gamma0.048
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism