The network for 'regulation of mapk cascade' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of mapk cascade

Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade.

NameDescriptionProbabilityFunc Analog Organism
msp-78Protein MSP-780.637
bar-1Protein BAR-10.603
egl-18Protein EGL-180.370
msp-49Protein MSP-490.368
mpk-1Protein MPK-10.345
dpy-22Protein DPY-220.334
nhr-6Protein NHR-60.325
mec-2Protein MEC-20.319
msp-77Protein MSP-770.255
abl-1Protein ABL-10.243
msp-36Protein MSP-360.221
tbb-4Protein TBB-40.217
msp-59Protein MSP-590.198
msp-3Protein MSP-30.181
msp-50Protein MSP-500.178
msp-31Protein MSP-310.173
glp-1Protein GLP-10.169
lin-45Protein LIN-450.168
cutl-24Protein CUTL-240.161
lin-25Protein LIN-250.160
msp-65Protein MSP-650.160
sem-5Protein SEM-50.154
msp-74Protein MSP-740.151
sma-6Protein SMA-60.142
lat-1Protein LAT-10.140
vab-3Protein VAB-30.137
chd-7Protein CHD-70.136
ncam-1Protein NCAM-10.135
CELE_Y59E9AR.7Protein Y59E9AR.70.133
pal-1Protein PAL-10.128
K08E3.5Protein K08E3.50.127
sma-1Protein SMA-10.127
msp-38Protein MSP-380.122
tps-1Protein TPS-10.120
msp-76Protein MSP-760.111
magi-1Protein MAGI-10.104
msp-79Protein MSP-790.102
inx-3Protein INX-30.102
msp-33Protein MSP-330.102
msp-55Protein MSP-550.102
mek-2Protein MEK-20.098
mig-15Protein MIG-150.096
F55F8.9Protein F55F8.90.095
ceh-20Protein CEH-200.092
pry-1Protein PRY-10.090
ZK1248.17Protein ZK1248.170.090
btbd-10Protein BTBD-100.089
nipi-3Protein NIPI-30.088
frm-7Protein FRM-70.084
pqn-44Protein PQN-440.083
zak-1Protein ZAK-10.081
let-60Protein LET-600.079
tol-1Protein TOL-10.079
par-3Protein PAR-30.078
sax-7Protein SAX-70.074
msp-45Protein MSP-450.072
inx-4Protein INX-40.072
msp-152Protein MSP-1520.072
rpm-1Protein RPM-10.071
egl-15Protein EGL-150.071
egl-27Protein EGL-270.069
gap-2Protein GAP-20.069
msp-10Protein MSP-100.065
axl-1Protein AXL-10.064
cap-2Protein CAP-20.064
ldb-1Protein LDB-10.064
eps-8Protein EPS-80.062
Y43H11AL.1Protein Y43H11AL.10.061
zyg-9Protein ZYG-90.060
F39B2.1Protein F39B2.10.058
C14B1.2Protein C14B1.20.057
mes-3Protein MES-30.056
ubc-3Protein UBC-30.056
msp-32Protein MSP-320.056
daf-19Protein DAF-190.055
sek-1Protein SEK-10.055
inx-5Protein INX-50.055
frm-2Protein FRM-20.053
unc-32Protein UNC-320.053
unc-7Protein UNC-70.053
hum-5Protein HUM-50.053
R03H10.2Protein R03H10.20.052
lin-11Protein LIN-110.052
cam-1Protein CAM-10.052
zhp-3Protein ZHP-30.052
spc-1Protein SPC-10.052
unc-9Protein UNC-90.051
pqn-51Protein PQN-510.050
ykt-6Protein YKT-60.050
psf-1Protein PSF-10.050
plc-1Protein PLC-10.050
daf-4Protein DAF-40.049
swsn-2.1Protein SWSN-2.10.047
ksr-1Protein KSR-10.047
tir-1Protein TIR-10.045
rhi-1Protein RHI-10.045
msp-142Protein MSP-1420.043
snx-17Protein SNX-170.043
fln-2Protein FLN-20.042
msp-63Protein MSP-630.042
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
bmp2bbone morphogenetic protein 2b0.243
twist1atwist1a0.173
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.148
efnb2aephrin B2a0.094
dkk1bdickkopf 1b0.091
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.085
wu:fv91b12wu:fv91b120.082
bambiaBMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a0.076
lamc1laminin, gamma 10.068
olfm1aolfactomedin 1a0.064
odc1ornithine decarboxylase 10.063
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.062
zbtb4zinc finger and BTB domain containing 40.061
fn1fibronectin 10.058
nf1aneurofibromin 1a0.054
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.053
hoxa2bhomeo box A2b0.051
tlr3toll-like receptor 30.051
crip2cysteine-rich protein 20.050
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.050
bdnfbrain-derived neurotrophic factor0.050
tmem2transmembrane protein 20.048
rnd3aRho family GTPase 3a0.048
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.047
rhoabras homolog gene family, member Ab0.045
igfbp3insulin-like growth factor binding protein 30.045
brd2abromodomain-containing 2a0.044
nod1nucleotide-binding oligomerization domain containing 10.043
nrp1aneuropilin 1a0.043
tie1endothelium-specific receptor tyrosine kinase 10.043
plcg1phospholipase C, gamma 10.041
gro2groucho 20.041
furinbfurin (paired basic amino acid cleaving enzyme) b0.041
crestincrestin0.040
pard6gbpar-6 partitioning defective 6 homolog gamma B (C. elegans)0.040
gdf6agrowth differentiation factor 6a0.039
lef1lymphocyte enhancer binding factor 10.038
pycardPYD and CARD domain containing0.038
vipr2vasoactive intestinal peptide receptor 20.038
cnn2calponin 20.038
mbtps1membrane-bound transcription factor protease, site 10.037
tob1atransducer of ERBB2, 1a0.037
fgf3fibroblast growth factor 30.037
jag2jagged 20.037
pcp4aPurkinje cell protein 4a0.035
adipor2adiponectin receptor 20.035
acvr2aactivin receptor IIa0.035
gclmglutamate-cysteine ligase, modifier subunit0.035
igf2binsulin-like growth factor 2b0.035
baxabcl2-associated X protein, a0.032
tagln2transgelin 20.032
mpped2metallophosphoesterase domain containing 20.032
rargaretinoic acid receptor gamma a0.032
kiss1rbKISS1 receptor b0.031
trpm7transient receptor potential cation channel, subfamily M, member 70.031
leprleptin receptor0.030
frzbfrizzled-related protein0.029
igf1insulin-like growth factor 10.029
dag1dystroglycan 10.028
jag1bjagged 1b0.028
pcsk5bproprotein convertase subtilisin/kexin type 5b0.028
lama5laminin, alpha 50.027
traf4atnf receptor-associated factor 4a0.027
nrp2aneuropilin 2a0.027
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.027
tbpTATA box binding protein0.027
sfrp1bsecreted frizzled-related protein 1b0.027
kitakit receptor a0.026
mapk1mitogen-activated protein kinase 10.026
fesfeline sarcoma oncogene0.026
inhbaainhibin, beta Aa0.025
smad7MAD, mothers against decapentaplegic homolog 7 (Drosophila)0.025
aox3aldehyde oxidase 30.025
pax7bpaired box gene 7b0.025
spry2sprouty homolog 20.025
arhgef7bRho guanine nucleotide exchange factor (GEF) 7b0.025
sf3b1splicing factor 3b, subunit 10.025
wnt4awingless-type MMTV integration site family, member 4a0.025
pobpartial optokinetic response b0.024
osr1odd-skipped related 1 (Drosophila)0.024
ghragrowth hormone receptor a0.024
mstnbmyostatin b0.024
ptenaphosphatase and tensin homolog A0.024
atp6v1hATPase, H+ transporting, lysosomal, V1 subunit H0.024
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.024
fasFas (TNF receptor superfamily, member 6)0.024
cd63Cd63 antigen0.023
dzip1DAZ interacting protein 10.023
zgc:85866zgc:858660.023
ywhae1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 10.023
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.023
sall1asal-like 1a (Drosophila)0.023
erbb3av-erb-b2 erythroblastic leukemia viral oncogene homolog 3a0.023
scinlbscinderin like b0.023
ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.023
cltcaclathrin, heavy polypeptide a (Hc)0.022
mitfamicrophthalmia-associated transcription factor a0.022
cdh2cadherin 2, neuronal0.022
her6hairy-related 60.022
lmo4aLIM domain only 4a0.022
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Pi3K92ECG4141 gene product from transcript CG4141-RB0.843
SmoxSmad on X0.709
Ras85DRas oncogene at 85D0.669
MadMothers against dpp0.640
stcksteamer duck0.610
saxsaxophone0.591
NetBNetrin-B0.572
pucpuckered0.549
pnutpeanut0.525
hephemipterous0.501
chicoCG5686 gene product from transcript CG5686-RB0.484
shishibire0.480
Akt1CG4006 gene product from transcript CG4006-RA0.474
rlrolled0.453
Nrx-IVNeurexin IV0.446
Adf1Adh transcription factor 10.423
ctpcut up0.414
Rac2CG8556 gene product from transcript CG8556-RA0.399
G-oalpha47AG protein oalpha 47A0.398
keykenny0.393
shnschnurri0.391
rheaCG6831 gene product from transcript CG6831-RA0.377
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.365
bskbasket0.364
p120ctnAdherens junction protein p1200.347
phlpole hole0.338
kaykayak0.334
p38bCG7393 gene product from transcript CG7393-RA0.333
Stat92ESignal-transducer and activator of transcription protein at 92E0.327
ecdecdysoneless0.324
cbscentrosomin's beautiful sister0.323
lqfliquid facets0.322
htlheartless0.309
edechinoid0.305
rhorhomboid0.303
Mpk2CG5475 gene product from transcript CG5475-RB0.299
Rab5Rab-protein 50.283
babobaboon0.278
rokRho-kinase0.267
JraJun-related antigen0.260
rutrutabaga0.258
MedMedea0.251
dapdacapo0.245
skpACG16983 gene product from transcript CG16983-RD0.239
wdbwiderborst0.238
spensplit ends0.236
Src42ASrc oncogene at 42A0.233
Klp64DKinesin-like protein at 64D0.231
RhebCG1081 gene product from transcript CG1081-RA0.229
Sema-1aCG18405 gene product from transcript CG18405-RD0.227
hipkhomeodomain interacting protein kinase0.224
Atg1Autophagy-specific gene 10.223
tamoCG4057 gene product from transcript CG4057-RA0.220
CG10267CG10267 gene product from transcript CG10267-RB0.216
mewmultiple edematous wings0.216
mbcmyoblast city0.214
PvrPDGF- and VEGF-receptor related0.204
mttmangetout0.198
Myo31DFMyosin 31DF0.193
sggshaggy0.184
spispitz0.183
aopanterior open0.183
WASpCG1520 gene product from transcript CG1520-RA0.183
trioCG18214 gene product from transcript CG18214-RA0.180
Ptp69DProtein tyrosine phosphatase 69D0.180
mib1mind bomb 10.178
Irk2Inwardly rectifying potassium channel 20.166
PGRP-LFPeptidoglycan recognition protein LF0.166
CdsACDP diglyceride synthetase0.166
Cdc42CG12530 gene product from transcript CG12530-RA0.166
plexBplexin B0.162
PGRP-LCPeptidoglycan recognition protein LC0.161
mysmyospheroid0.160
ShcSHC-adaptor protein0.155
armarmadillo0.154
Ras64BRas oncogene at 64B0.149
Rab7Rab-protein 70.149
linlines0.148
ApcAPC-like0.142
egreiger0.142
CkIIalphaCasein kinase II alpha subunit0.142
LIMK1LIM-kinase10.141
tkvthickveins0.141
DadDaughters against dpp0.140
CaMKIICalcium/calmodulin-dependent protein kinase II0.137
slislit0.136
sbbscribbler0.134
PGRP-SDCG7496 gene product from transcript CG7496-RA0.133
fl(2)dfemale lethal d0.131
SosSon of sevenless0.124
drkdownstream of receptor kinase0.124
az2CG1605 gene product from transcript CG1605-RA0.123
CG4168CG4168 gene product from transcript CG4168-RA0.123
ATP7CG1886 gene product from transcript CG1886-RB0.122
Sra-1specifically Rac1-associated protein 10.120
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.119
PtenCG5671 gene product from transcript CG5671-RB0.117
rawCG12437 gene product from transcript CG12437-RB0.117
CG1792CG1792 gene product from transcript CG1792-RA0.115
AttAAttacin-A0.113
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor1.000
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide1.000
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence1.000
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)1.000
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide1.000
SMAD2SMAD family member 20.999
MAPK14mitogen-activated protein kinase 140.999
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.998
MAP3K7mitogen-activated protein kinase kinase kinase 70.998
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.997
MAPK1mitogen-activated protein kinase 10.997
SHC1SHC (Src homology 2 domain containing) transforming protein 10.997
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.997
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.996
MAP3K3mitogen-activated protein kinase kinase kinase 30.995
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.995
IRAK1interleukin-1 receptor-associated kinase 10.992
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.991
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.988
SMAD3SMAD family member 30.986
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.985
FGFR2fibroblast growth factor receptor 20.984
MAP2K1mitogen-activated protein kinase kinase 10.984
FASFas (TNF receptor superfamily, member 6)0.982
FGFR1fibroblast growth factor receptor 10.980
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.978
CCR5chemokine (C-C motif) receptor 50.977
AKT1v-akt murine thymoma viral oncogene homolog 10.975
CSNK1Ecasein kinase 1, epsilon0.974
ESR1estrogen receptor 10.972
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.969
CEACAM1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)0.968
LRRK2leucine-rich repeat kinase 20.968
PTPN1protein tyrosine phosphatase, non-receptor type 10.967
PLCG1phospholipase C, gamma 10.966
MAP3K5mitogen-activated protein kinase kinase kinase 50.965
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.964
DUSP1dual specificity phosphatase 10.963
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.963
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.961
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.958
FGF1fibroblast growth factor 1 (acidic)0.957
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.957
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.952
MAPK8mitogen-activated protein kinase 80.952
BCAR1breast cancer anti-estrogen resistance 10.952
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.946
SMAD7SMAD family member 70.946
CAV1caveolin 1, caveolae protein, 22kDa0.945
MAPK3mitogen-activated protein kinase 30.944
GHRgrowth hormone receptor0.938
SFNstratifin0.936
GAB1GRB2-associated binding protein 10.934
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 10.933
PTENphosphatase and tensin homolog0.929
ERBB2IPerbb2 interacting protein0.928
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.927
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.918
IRAK2interleukin-1 receptor-associated kinase 20.916
CHUKconserved helix-loop-helix ubiquitous kinase0.912
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.910
CALM1calmodulin 1 (phosphorylase kinase, delta)0.908
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.908
TRAF3TNF receptor-associated factor 30.904
TEKTEK tyrosine kinase, endothelial0.891
MYD88myeloid differentiation primary response gene (88)0.890
SQSTM1sequestosome 10.890
PTK2PTK2 protein tyrosine kinase 20.887
GSK3Bglycogen synthase kinase 3 beta0.877
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.874
ZNF43zinc finger protein 430.874
ARRB1arrestin, beta 10.867
TRAF5TNF receptor-associated factor 50.867
TRAF6TNF receptor-associated factor 60.864
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.862
BIRC3baculoviral IAP repeat containing 30.860
BMPR1Abone morphogenetic protein receptor, type IA0.857
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.853
FGBfibrinogen beta chain0.849
MAP2K4mitogen-activated protein kinase kinase 40.835
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.834
ILKintegrin-linked kinase0.832
MAP3K1mitogen-activated protein kinase kinase kinase 10.830
SKILSKI-like oncogene0.829
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.825
PIK3R5phosphoinositide-3-kinase, regulatory subunit 50.819
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.814
CCNE1cyclin E10.810
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.807
BRAFv-raf murine sarcoma viral oncogene homolog B10.789
MAP4K1mitogen-activated protein kinase kinase kinase kinase 10.783
BBS10Bardet-Biedl syndrome 100.782
STAT5Asignal transducer and activator of transcription 5A0.776
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.775
ZNF746zinc finger protein 7460.771
PTPN11protein tyrosine phosphatase, non-receptor type 110.771
METmet proto-oncogene (hepatocyte growth factor receptor)0.771
PRKCAprotein kinase C, alpha0.769
GUCY2Cguanylate cyclase 2C (heat stable enterotoxin receptor)0.766
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.765
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Grb2growth factor receptor bound protein 21.000
Ptenphosphatase and tensin homolog1.000
Ptpn11protein tyrosine phosphatase, non-receptor type 110.999
CblCasitas B-lineage lymphoma0.998
Apcadenomatosis polyposis coli0.998
Shc1src homology 2 domain-containing transforming protein C10.995
Efnb2ephrin B20.993
Traf6TNF receptor-associated factor 60.991
Inpp5dinositol polyphosphate-5-phosphatase D0.984
Axin1axin 10.983
Cd44CD44 antigen0.978
Ghrgrowth hormone receptor0.976
Csf1colony stimulating factor 1 (macrophage)0.975
Egfrepidermal growth factor receptor0.967
Cav1caveolin 1, caveolae protein0.964
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.962
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.953
Ctnnb1catenin (cadherin associated protein), beta 10.951
Mapk8mitogen-activated protein kinase 80.951
Ccl2chemokine (C-C motif) ligand 20.950
Prkceprotein kinase C, epsilon0.948
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.947
Leprleptin receptor0.945
Acvr1activin A receptor, type 10.944
Tgfb2transforming growth factor, beta 20.940
AxlAXL receptor tyrosine kinase0.934
Smad6MAD homolog 6 (Drosophila)0.933
Cd40CD40 antigen0.927
Stat3signal transducer and activator of transcription 30.916
Tnfaip3tumor necrosis factor, alpha-induced protein 30.911
Wnt5awingless-related MMTV integration site 5A0.909
Map3k7mitogen-activated protein kinase kinase kinase 70.906
Tnftumor necrosis factor0.905
Abl1c-abl oncogene 1, non-receptor tyrosine kinase0.904
Mapk14mitogen-activated protein kinase 140.900
Dvl2dishevelled 2, dsh homolog (Drosophila)0.900
Tbx3T-box 30.895
SrcRous sarcoma oncogene0.892
Kiss1KiSS-1 metastasis-suppressor0.891
Il6stinterleukin 6 signal transducer0.888
FynFyn proto-oncogene0.885
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.882
Smad4MAD homolog 4 (Drosophila)0.879
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.875
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.859
Ptk2PTK2 protein tyrosine kinase 20.857
Il1r1interleukin 1 receptor, type I0.854
Dok1docking protein 10.852
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.832
Tgfbr2transforming growth factor, beta receptor II0.832
Gli3GLI-Kruppel family member GLI30.831
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.826
Prrx1paired related homeobox 10.825
Cd22CD22 antigen0.817
Ephb3Eph receptor B30.810
Smad3MAD homolog 3 (Drosophila)0.805
Apoeapolipoprotein E0.801
Ccr1chemokine (C-C motif) receptor 10.799
Gpc3glypican 30.795
Plcg1phospholipase C, gamma 10.787
Pthlhparathyroid hormone-like peptide0.785
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.777
Mapk1mitogen-activated protein kinase 10.775
Adam17a disintegrin and metallopeptidase domain 170.768
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.765
Hbegfheparin-binding EGF-like growth factor0.764
Vaspvasodilator-stimulated phosphoprotein0.763
Bmpr1abone morphogenetic protein receptor, type 1A0.760
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.755
Fras1Fraser syndrome 1 homolog (human)0.754
Fcgr2bFc receptor, IgG, low affinity IIb0.752
Trp63transformation related protein 630.746
Ptgs2prostaglandin-endoperoxide synthase 20.738
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.737
Fzd4frizzled homolog 4 (Drosophila)0.732
Fgfr3fibroblast growth factor receptor 30.731
Wnt3awingless-related MMTV integration site 3A0.731
Cx3cr1chemokine (C-X3-C) receptor 10.727
Cdoncell adhesion molecule-related/down-regulated by oncogenes0.721
Gsk3bglycogen synthase kinase 3 beta0.720
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.720
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.718
Insrinsulin receptor0.709
Irs1insulin receptor substrate 10.707
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.706
Dvl1dishevelled, dsh homolog 1 (Drosophila)0.704
Nr3c1nuclear receptor subfamily 3, group C, member 10.704
Ifngr1interferon gamma receptor 10.702
Ahraryl-hydrocarbon receptor0.699
C3ar1complement component 3a receptor 10.696
Map3k3mitogen-activated protein kinase kinase kinase 30.695
Esr1estrogen receptor 1 (alpha)0.692
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.685
Pax2paired box gene 20.685
Klf7Kruppel-like factor 7 (ubiquitous)0.684
Spnb2spectrin beta 20.677
Spry4sprouty homolog 4 (Drosophila)0.671
Bdnfbrain derived neurotrophic factor0.671
Cyldcylindromatosis (turban tumor syndrome)0.666
Rac1RAS-related C3 botulinum substrate 10.664
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.758
Bcanbrevican0.585
Itgamintegrin, alpha M0.532
Jak1Janus kinase 10.529
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.494
Utrnutrophin0.469
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.417
Ncanneurocan0.398
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.374
Tnftumor necrosis factor (TNF superfamily, member 2)0.367
Syt10synaptotagmin X0.367
Ptafrplatelet-activating factor receptor0.363
Ptprcprotein tyrosine phosphatase, receptor type, C0.354
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.333
Sstr5somatostatin receptor 50.332
Irs1insulin receptor substrate 10.322
Ptbp1polypyrimidine tract binding protein 10.308
Cdh6cadherin 60.305
Kcnj4potassium inwardly-rectifying channel, subfamily J, member 40.302
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.300
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.300
Kcna3potassium voltage-gated channel, shaker-related subfamily, member 30.294
Mr1major histocompatibility complex, class I-related0.289
Prkchprotein kinase C, eta0.285
Adora2aadenosine A2a receptor0.284
Fgfr2fibroblast growth factor receptor 20.280
Gna15guanine nucleotide binding protein, alpha 150.276
Ptger2prostaglandin E receptor 2 (subtype EP2)0.269
Tgfbr2transforming growth factor, beta receptor II0.263
Grm7glutamate receptor, metabotropic 70.260
Prdm2PR domain containing 2, with ZNF domain0.253
Map2microtubule-associated protein 20.253
Egfrepidermal growth factor receptor0.252
Metmet proto-oncogene0.250
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.248
Ednrbendothelin receptor type B0.246
Grip1glutamate receptor interacting protein 10.240
Olr287olfactory receptor 2870.239
Sellselectin L0.237
Creb1cAMP responsive element binding protein 10.228
Hpcal4hippocalcin-like 40.224
Lphn2latrophilin 20.222
Dmddystrophin0.220
RGD1564664similar to LOC387763 protein0.217
Adam17ADAM metallopeptidase domain 170.217
Mapk1mitogen activated protein kinase 10.216
Syt8synaptotagmin VIII0.216
Lpllipoprotein lipase0.215
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.215
Iappislet amyloid polypeptide0.214
Sirpasignal-regulatory protein alpha0.213
Il1ainterleukin 1 alpha0.206
Svs1seminal vesicle secretory protein 10.205
Prkg2protein kinase, cGMP-dependent, type II0.201
Map3k3mitogen activated protein kinase kinase kinase 30.199
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.198
Cyp27b1cytochrome P450, family 27, subfamily b, polypeptide 10.196
Grpgastrin releasing peptide0.195
Jtbjumping translocation breakpoint0.194
Vegfavascular endothelial growth factor A0.190
MGC112715hypothetical protein LOC6908990.188
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.185
Tcf4transcription factor 40.184
Crip2cysteine-rich protein 20.183
RhagRh-associated glycoprotein0.181
Robo1roundabout homolog 1 (Drosophila)0.179
Oprm1opioid receptor, mu 10.178
Klf6Kruppel-like factor 60.177
Pxnpaxillin0.177
Acracrosin0.176
Gzmbgranzyme B0.176
Pfkfb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 20.175
Calcrlcalcitonin receptor-like0.173
Il8rainterleukin 8 receptor, alpha0.173
Cx3cr1chemokine (C-X3-C motif) receptor 10.169
Rgs9regulator of G-protein signaling 90.168
Prlhrprolactin releasing hormone receptor0.167
Nr5a2nuclear receptor subfamily 5, group A, member 20.166
Map3k1mitogen activated protein kinase kinase kinase 10.165
Rgs14regulator of G-protein signaling 140.163
Olr837olfactory receptor 8370.161
Mpeg1macrophage expressed 10.159
Homer3homer homolog 3 (Drosophila)0.159
Nr4a3nuclear receptor subfamily 4, group A, member 30.159
Crhbpcorticotropin releasing hormone binding protein0.158
Nab1Ngfi-A binding protein 10.157
Barhl2BarH-like homeobox 20.154
Ctsjcathepsin J0.154
Agtr2angiotensin II receptor, type 20.153
Hpcahippocalcin0.152
Stk10serine/threonine kinase 100.152
Gjb4gap junction protein, beta 40.150
Mapk9mitogen-activated protein kinase 90.150
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.150
Nek9NIMA (never in mitosis gene a)- related kinase 90.150
Syt2synaptotagmin II0.148
Adrb1adrenergic, beta-1-, receptor0.148
Gria2glutamate receptor, ionotropic, AMPA 20.147
Fgf16fibroblast growth factor 160.147
Il9rinterleukin 9 receptor0.146
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
PBS2Pbs2p0.989
NBP2Nbp2p0.977
SSK2Ssk2p0.971
STE7Ste7p0.905
SLT2Slt2p0.860
STE4Ste4p0.844
FUS3Fus3p0.836
MSG5Msg5p0.816
BCK1Bck1p0.790
KSS1Kss1p0.743
CPR1Cpr1p0.612
STE5Ste5p0.437
STE20Ste20p0.343
BMH1Bmh1p0.316
STE11Ste11p0.316
SLA2Sla2p0.238
AHP1Ahp1p0.234
CYR1Cyr1p0.217
FAR1Far1p0.164
KIC1Kic1p0.159
PTC1Ptc1p0.159
CDC55Cdc55p0.154
ZDS1Zds1p0.148
BEM1Bem1p0.147
IRA1Ira1p0.145
CAK1Cak1p0.141
ASK10Ask10p0.134
CDC34Cdc34p0.114
HOS4Hos4p0.109
SSK1Ssk1p0.103
TRX2Trx2p0.100
CDC24Cdc24p0.093
SNT1Snt1p0.093
ALD6Ald6p0.092
RLM1Rlm1p0.089
LHS1Lhs1p0.082
EBS1Ebs1p0.080
KDX1Kdx1p0.067
ARF2Arf2p0.067
SSK22Ssk22p0.066
SHO1Sho1p0.061
UFO1Ufo1p0.059
ROM2Rom2p0.056
DBF2Dbf2p0.051
YEL1Yel1p0.050
CSI1Csi1p0.050
BCK2Bck2p0.045
SSN8Ssn8p0.044
HOG1Hog1p0.043
DIA2Dia2p0.042
FUS2Fus2p0.041
CLA4Cla4p0.039
YHB1Yhb1p0.039
SIF2Sif2p0.035
SKP1Skp1p0.035
PPH21Pph21p0.035
BOI1Boi1p0.034
HOS2Hos2p0.034
RPN13Rpn13p0.034
OYE2Oye2p0.033
YJR084Whypothetical protein0.033
CRG1Crg1p0.032
HOR7Hor7p0.032
TEC1Tec1p0.031
DIG1Dig1p0.031
HST1Hst1p0.030
ZWF1Zwf1p0.030
PCI8Pci8p0.030
EHT1Eht1p0.029
CHS1Chs1p0.029
CRZ1Crz1p0.028
RHO4Rho4p0.027
RGD2Rgd2p0.027
VPS5Vps5p0.026
CNS1Cns1p0.026
RHO1Rho1p0.025
EAF3Eaf3p0.024
YJR141Whypothetical protein0.023
CCS1Ccs1p0.023
SKT5Skt5p0.023
NAP1Nap1p0.023
YPL088Whypothetical protein0.023
VMA13Vma13p0.022
FAA4Faa4p0.022
SHP1Shp1p0.021
ATP3Atp3p0.021
BNI1Bni1p0.020
STE2Ste2p0.020
SKM1Skm1p0.020
CSN9Csn9p0.020
BIT61Bit61p0.019
PTC3Ptc3p0.019
ENT3Ent3p0.019
CCT2Cct2p0.019
RAS2Ras2p0.019
YDR514Chypothetical protein0.019
CKB1Ckb1p0.018
SIL1Sil1p0.018
LTV1Ltv1p0.017
ALG13Alg13p0.017