The network for 'gpi anchor biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

gpi anchor biosynthetic process

The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.

NameDescriptionProbabilityFunc Analog Organism
LAS21Las21p0.984
GAB1Gab1p0.976
GWT1Gwt1p0.793
GPI17Gpi17p0.771
ALG6Alg6p0.672
GPI2Gpi2p0.635
GAA1Gaa1p0.590
PER1Per1p0.585
GPI16Gpi16p0.392
YJR015Whypothetical protein0.378
GPI8Gpi8p0.349
SFB3Sfb3p0.151
MCD4Mcd4p0.144
ERD2Erd2p0.133
GPI11Gpi11p0.105
SEC24Sec24p0.101
GPI13Gpi13p0.096
CNE1Cne1p0.093
GUP1Gup1p0.085
YLR036Chypothetical protein0.084
ARV1Arv1p0.078
SPF1Spf1p0.077
SEC59Sec59p0.072
CHS7Chs7p0.071
YJR012Chypothetical protein0.068
RFT1Rft1p0.064
ALG12Alg12p0.061
PMT3Pmt3p0.061
ELO1Elo1p0.060
SED4Sed4p0.057
GPI1Gpi1p0.056
GPI19Gpi19p0.056
YGL140Chypothetical protein0.051
VBA2Vba2p0.049
SRD1Srd1p0.048
BST1Bst1p0.047
YAR068Whypothetical protein0.044
DIE2Die2p0.044
YER186Chypothetical protein0.042
SFT1Sft1p0.041
ISC1Isc1p0.040
YOL038C-Ahypothetical protein0.039
CUP1-1Cup1-1p0.039
OSH7Osh7p0.039
TAD2Tad2p0.037
YAR066Whypothetical protein0.037
SEC31Sec31p0.036
YLR264C-Ahypothetical protein0.036
ARP10Arp10p0.036
YNR061Chypothetical protein0.036
YLR162Whypothetical protein0.036
LEU2Leu2p0.034
PFA4Pfa4p0.034
RRN5Rrn5p0.034
NHX1Nhx1p0.034
YLR042Chypothetical protein0.033
MER1Mer1p0.033
TSC3Tsc3p0.033
BET3Bet3p0.031
FMT1Fmt1p0.031
LHS1Lhs1p0.031
MST27Mst27p0.030
PRS2Prs2p0.029
YPR153Whypothetical protein0.029
ZPS1Zps1p0.029
OPT2Opt2p0.029
ATP6Atp6p0.029
AUA1Aua1p0.029
YPR157Whypothetical protein0.028
SPL2Spl2p0.028
ARO10Aro10p0.028
SCS7Scs7p0.028
ROT2Rot2p0.028
YCH1Ych1p0.027
YLR040Chypothetical protein0.027
YSC83Ysc83p0.027
CPD1Cpd1p0.027
SMF3Smf3p0.026
HPF1Hpf1p0.026
YCR023Chypothetical protein0.026
OSM1Osm1p0.026
MF(ALPHA)2Mf(alpha)2p0.026
ARG8Arg8p0.026
YBR013Chypothetical protein0.026
YLR126Chypothetical protein0.026
BNA4Bna4p0.026
NRG2Nrg2p0.026
YHR177Whypothetical protein0.026
YJL181Whypothetical protein0.026
ERV15Erv15p0.026
YHL017Whypothetical protein0.025
VBA1Vba1p0.025
AXL2Axl2p0.025
BSC1Bsc1p0.025
QNS1Qns1p0.025
YOL013W-Ahypothetical protein0.025
BDS1Bds1p0.025
CWH43Cwh43p0.025
ALT2Alt2p0.025
PAD1Pad1p0.024
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
GPAA1glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)0.071
PIGTphosphatidylinositol glycan anchor biosynthesis, class T0.062
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
5730494N06RikRIKEN cDNA 5730494N06 gene0.113
Immp1lIMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)0.106
1810030N24RikRIKEN cDNA 1810030N24 gene0.105
Atp5sATP synthase, H+ transporting, mitochondrial F0 complex, subunit s0.089
Fntafarnesyltransferase, CAAX box, alpha0.051
Tcaptitin-cap0.030
Vti1bvesicle transport through interaction with t-SNAREs 1B homolog0.027
1110058L19RikRIKEN cDNA 1110058L19 gene0.026
Slc25a39solute carrier family 25, member 390.025
Pdcd2programmed cell death 20.025
Ptpn2protein tyrosine phosphatase, non-receptor type 20.024
Med31mediator of RNA polymerase II transcription, subunit 31 homolog (yeast)0.021
Acyp1acylphosphatase 1, erythrocyte (common) type0.020
Ube2tubiquitin-conjugating enzyme E2T (putative)0.018
Tmem218transmembrane protein 2180.018
0610009B22RikRIKEN cDNA 0610009B22 gene0.018
Pgam2phosphoglycerate mutase 20.017
Pigophosphatidylinositol glycan anchor biosynthesis, class O0.017
Trim54tripartite motif-containing 540.015
Tab3TGF-beta activated kinase 1/MAP3K7 binding protein 30.015
Polr2kpolymerase (RNA) II (DNA directed) polypeptide K0.015
Ccdc90bcoiled-coil domain containing 90B0.015
Eef1a2eukaryotic translation elongation factor 1 alpha 20.015
Rbm15RNA binding motif protein 150.014
Polr3kpolymerase (RNA) III (DNA directed) polypeptide K0.014
Tprgltransformation related protein 63 regulated like0.013
Bnip3BCL2/adenovirus E1B interacting protein 30.013
Rab28RAB28, member RAS oncogene family0.013
Rnf7ring finger protein 70.013
Cetn2centrin 20.012
Pvalbparvalbumin0.012
Pex3peroxisomal biogenesis factor 30.012
Unc50unc-50 homolog (C. elegans)0.011
Tmem128transmembrane protein 1280.011
1110005A03RikRIKEN cDNA 1110005A03 gene0.011
Isca1iron-sulfur cluster assembly 1 homolog (S. cerevisiae)0.011
Camlcalcium modulating ligand0.011
Brp44brain protein 440.011
1500031L02RikRIKEN cDNA 1500031L02 gene0.011
Paip2polyadenylate-binding protein-interacting protein 20.010
Atad3aATPase family, AAA domain containing 3A0.010
Spcs1signal peptidase complex subunit 1 homolog (S. cerevisiae)0.010
H47histocompatibility 470.010
Fam134bfamily with sequence similarity 134, member B0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism