The network for 'negative regulation of nitrogen compound metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of nitrogen compound metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.

NameDescriptionProbabilityFunc Analog Organism
HHT1Hht1p0.998
RPD3Rpd3p0.998
SIN3Sin3p0.988
SIR2Sir2p0.980
SET1Set1p0.967
RLF2Rlf2p0.964
HHF1Hhf1p0.950
RPN4Rpn4p0.946
GLN3Gln3p0.943
RIF1Rif1p0.938
CTK1Ctk1p0.932
PHO23Pho23p0.931
ASF1Asf1p0.922
SIN4Sin4p0.908
SDS3Sds3p0.908
RAP1Rap1p0.896
HAT1Hat1p0.891
RCO1Rco1p0.880
SNF1Snf1p0.875
DIA2Dia2p0.850
GAL11Gal11p0.850
SIR4Sir4p0.848
SAS2Sas2p0.835
SRP1Srp1p0.827
CTF18Ctf18p0.826
RXT2Rxt2p0.820
RAD9Rad9p0.818
BDF1Bdf1p0.807
ORC5Orc5p0.805
NRG1Nrg1p0.790
MED2Med2p0.777
YCS4Ycs4p0.765
ORC2Orc2p0.752
HDA1Hda1p0.748
SIR3Sir3p0.746
FKH2Fkh2p0.742
YAK1Yak1p0.740
HRK1Hrk1p0.734
CCR4Ccr4p0.726
ISW2Isw2p0.725
GLC7Glc7p0.725
SNT1Snt1p0.717
SNF5Snf5p0.714
UME6Ume6p0.710
SWD1Swd1p0.693
RRS1Rrs1p0.692
GCR2Gcr2p0.687
HTB1Htb1p0.682
RIM101Rim101p0.680
CTI6Cti6p0.674
RNR4Rnr4p0.668
DEP1Dep1p0.663
NUT1Nut1p0.660
HMO1Hmo1p0.657
HHO1Hho1p0.631
PGD1Pgd1p0.630
CDC45Cdc45p0.624
SSN3Ssn3p0.623
HIR1Hir1p0.615
VID22Vid22p0.609
ADA2Ada2p0.608
MOT1Mot1p0.608
PHO4Pho4p0.595
IES3Ies3p0.592
MCM7Mcm7p0.587
CYC8Cyc8p0.583
SPT8Spt8p0.580
SSN8Ssn8p0.569
POL30Pol30p0.569
PAF1Paf1p0.563
HCM1Hcm1p0.562
HDA2Hda2p0.556
SPT16Spt16p0.553
DBP10Dbp10p0.552
MCM2Mcm2p0.545
ADR1Adr1p0.541
MET4Met4p0.540
HDA3Hda3p0.534
DOT6Dot6p0.529
RNR2Rnr2p0.528
SAS4Sas4p0.526
ORC3Orc3p0.526
KAP95Kap95p0.523
RIM20Rim20p0.521
SPT10Spt10p0.519
SSA2Ssa2p0.503
TOR1Tor1p0.502
MRC1Mrc1p0.488
LGE1Lge1p0.483
CDC14Cdc14p0.481
SUM1Sum1p0.481
YLR419Whypothetical protein0.476
CKA2Cka2p0.469
GDS1Gds1p0.465
BOP3Bop3p0.463
NTO1Nto1p0.457
SRM1Srm1p0.453
UME1Ume1p0.450
NUP133Nup133p0.447
IFH1Ifh1p0.445
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.906
pha-4Protein PHA-40.638
his-16Protein HIS-160.462
elt-6Protein ELT-60.395
zip-7Protein ZIP-70.374
his-46Protein HIS-460.324
nhr-67Protein NHR-670.278
daf-1Protein DAF-10.247
egl-13Protein EGL-130.246
let-502Protein LET-5020.241
rad-26Protein RAD-260.235
mes-4Protein MES-40.234
his-1Protein HIS-10.225
eya-1Protein EYA-10.221
his-61Protein HIS-610.205
egl-46Protein EGL-460.194
his-3Protein HIS-30.187
klp-19Protein KLP-190.180
mep-1Protein MEP-10.179
npp-22Protein NPP-220.179
hcp-3Protein HCP-30.172
lin-53Protein LIN-530.168
ran-1Protein RAN-10.167
prp-8Protein PRP-80.164
mix-1Protein MIX-10.162
his-5Protein HIS-50.162
his-64Protein HIS-640.151
inx-3Protein INX-30.151
ceh-32Protein CEH-320.147
T28C6.7Protein T28C6.70.136
his-31Protein HIS-310.134
C33A11.1Protein C33A11.10.133
his-48Protein HIS-480.132
jmjd-2Protein JMJD-20.131
his-42Protein HIS-420.131
attf-2Protein ATTF-20.129
hda-1Protein HDA-10.128
unc-62Protein UNC-620.123
his-62Protein HIS-620.122
daf-14Protein DAF-140.121
ztf-2Protein ZTF-20.120
tbx-8Protein TBX-80.117
hlh-11Protein HLH-110.114
patr-1Protein PATR-10.108
ceh-27Protein CEH-270.105
mca-1Protein MCA-10.100
rsp-1Protein RSP-10.100
mig-38Protein MIG-380.099
his-51Protein HIS-510.098
ras-1Protein RAS-10.098
sur-2Protein SUR-20.096
F39B2.1Protein F39B2.10.096
nrde-3Protein NRDE-30.096
spt-5Protein SPT-50.096
glp-1Protein GLP-10.096
sacy-1Protein SACY-10.096
lin-11Protein LIN-110.095
pbrm-1Protein PBRM-10.095
exc-7Protein EXC-70.095
atg-2Protein ATG-20.095
nhr-25Protein NHR-250.094
his-39Protein HIS-390.093
CELE_C24H12.5Protein C24H12.50.093
his-47Protein HIS-470.091
hda-3Protein HDA-30.091
pry-1Protein PRY-10.090
hlh-2Protein HLH-20.089
mab-5Protein MAB-50.088
pop-1Protein POP-10.088
irx-1Protein IRX-10.088
dcr-1Protein DCR-10.087
bar-1Protein BAR-10.086
his-52Protein HIS-520.085
his-68Protein HIS-680.085
rpt-2Protein RPT-20.085
F25H5.5Protein F25H5.50.084
mcm-5Protein MCM-50.083
sas-6Protein SAS-60.081
nhr-2Protein NHR-20.081
F40F4.7Protein F40F4.70.080
plc-1Protein PLC-10.080
CELE_C25A1.4Protein C25A1.40.080
prpf-4Protein PRPF-40.080
cnd-1Protein CND-10.079
zyg-9Protein ZYG-90.079
cam-1Protein CAM-10.079
dbl-1Protein DBL-10.079
lin-12Protein LIN-120.079
lin-35Protein LIN-350.078
zyg-1Protein ZYG-10.078
rnp-5Protein RNP-50.078
skp-1Protein SKP-10.078
prp-3Protein PRP-30.077
flh-2Protein FLH-20.077
his-38Protein HIS-380.076
cfim-2Protein CFIM-20.075
Y87G2A.1Protein Y87G2A.10.075
fkb-6Protein FKB-60.075
rsp-2Protein RSP-20.074
sox-2Protein SOX-20.074
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
gata6GATA-binding protein 60.740
ndr2nodal-related 20.583
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.563
bmp2bbone morphogenetic protein 2b0.557
gli1GLI-Kruppel family member 10.551
twist3twist30.486
chdchordin0.474
zic2azic family member 2 (odd-paired homolog, Drosophila), a0.472
sox9bSRY-box containing gene 9b0.457
tbx6T-box gene 60.403
esr2aestrogen receptor 2a0.392
foxi1forkhead box I10.386
snai1bsnail homolog 1b (Drosophila)0.363
pax8paired box gene 80.328
pkd2polycystic kidney disease 20.309
tfap2atranscription factor AP-2 alpha0.299
prox1prospero-related homeobox gene 10.292
atoh7atonal homolog 70.290
dnmt7DNA (cytosine-5-)-methyltransferase 70.289
foxa3forkhead box A30.278
otx2orthodenticle homolog 20.272
mab21l2mab-21-like 20.269
per2period homolog 2 (Drosophila)0.269
meis2.1myeloid ecotropic viral integration site 2.10.261
pou5f1POU domain, class 5, transcription factor 10.251
lhx5LIM homeobox 50.247
fli1afriend leukemia integration 1a0.246
her7hairy and enhancer of split related-70.238
wt1awilms tumor 1a0.236
pcnaproliferating cell nuclear antigen0.235
grem2gremlin 2, cysteine knot superfamily0.227
tp53tumor protein p530.227
isl1islet10.221
fgf3fibroblast growth factor 30.219
fzd7afrizzled homolog 7a0.204
notch1bnotch homolog 1b0.203
whsc1Wolf-Hirschhorn syndrome candidate 10.200
ripply1ripply10.197
ikzf1IKAROS family zinc finger 1 (Ikaros)0.195
hmx1H6 homeo box 10.191
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.183
mef2dmyocyte enhancer factor 2d0.181
socs3asuppressor of cytokine signaling 3a0.181
pbx1apre-B-cell leukemia transcription factor 1a0.180
pax6apaired box gene 6a0.180
fgf8afibroblast growth factor 8 a0.177
spawsouthpaw0.177
tbx2aT-box gene 2a0.175
otx1borthodenticle homolog 1b0.171
alcamaactivated leukocyte cell adhesion molecule a0.170
evx1even-skipped homeobox 10.170
hand2heart and neural crest derivatives expressed transcript 20.169
six1bsine oculis homeobox homolog 1b0.168
jag2jagged 20.167
dnmt1DNA (cytosine-5-)-methyltransferase 10.166
dlx1adistal-less homeobox gene 1a0.162
eomesaeomesodermin homolog a0.161
sox32SRY-box containing gene 320.160
tfe3btranscription factor binding to IGHM enhancer 3b0.156
hoxc4ahomeo box C4a0.156
hoxb1bhomeo box B1b0.155
nr2e3nuclear receptor subfamily 2, group E, member 30.154
nadl1.1neural adhesion molecule L1.10.154
fgf19fibroblast growth factor 190.152
dctdopachrome tautomerase0.152
adrb2aadrenergic receptor, beta 2a0.151
dlcdeltaC0.151
irx3biroquois homeobox protein 3b0.150
sox19aSRY-box containing gene 19a0.149
rx2retinal homeobox gene 20.148
msxemuscle segment homeobox E0.146
her1hairy-related 10.146
gro2groucho 20.145
pax6bpaired box gene 6b0.143
cebpaCCAAT/enhancer binding protein (C/EBP), alpha0.143
hp1bp3heterochromatin protein 1, binding protein 30.142
gata4GATA-binding protein 40.141
osr2odd-skipped related 2 (Drosophila)0.141
vcanaversican a0.140
crestincrestin0.140
setdb1aSET domain, bifurcated 1a0.140
dlx2adistal-less homeobox gene 2a0.138
ascl1aachaete-scute complex-like 1a (Drosophila)0.138
ventventral expressed homeobox0.137
tal1T-cell acute lymphocytic leukemia 10.136
ptch1patched 10.135
ntlano tail a0.134
gcm2glial cells missing homolog 2 (Drosophila)0.134
rarabretinoic acid receptor, alpha b0.134
junbjun B proto-oncogene0.133
ddx39bDEAD (Asp-Glu-Ala-Asp) box polypeptide 39b0.132
notch1anotch homolog 1a0.130
traf4atnf receptor-associated factor 4a0.129
ef1aelongation factor 1-alpha0.128
msxcmuscle segment homeobox C0.127
robo3roundabout homolog 30.127
gbx1gastrulation brain homeobox 10.126
pou3f3bPOU class 3 homeobox 3b0.125
meis3myeloid ecotropic viral integration site 30.123
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.123
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
kaykayak0.998
UbxUltrabithorax0.997
MadMothers against dpp0.996
Snr1Snf5-related 10.996
CtBPC-terminal Binding Protein0.993
atoatonal0.993
p53CG33336 gene product from transcript CG33336-RB0.993
hephemipterous0.992
trxtrithorax0.992
E(spl)Enhancer of split0.991
IswiImitation SWI0.977
Pp1-87BProtein phosphatase 1 at 87B0.976
smt3CG4494 gene product from transcript CG4494-RA0.976
wtswarts0.976
Rpd3CG7471 gene product from transcript CG7471-RA0.973
ScmSex comb on midleg0.968
cicubitus interruptus0.961
ash1absent, small, or homeotic discs 10.960
phylphyllopod0.956
Socs36ESuppressor of cytokine signaling at 36E0.952
dcodiscs overgrown0.948
slp1sloppy paired 10.948
nmonemo0.946
PcPolycomb0.945
lwrlesswright0.938
Sir2CG5216 gene product from transcript CG5216-RA0.937
gppgrappa0.935
mormoira0.933
grogroucho0.932
BEAF-32Boundary element-associated factor of 32kD0.927
Pka-C1cAMP-dependent protein kinase 10.927
araaraucan0.927
SceSex combs extra0.922
eygeyegone0.922
barrbarren0.917
ssspineless0.912
Pi3K92ECG4141 gene product from transcript CG4141-RB0.911
dacdachshund0.911
pbproboscipedia0.908
sogshort gastrulation0.908
rhorhomboid0.903
InRInsulin-like receptor0.900
prosprospero0.895
panpangolin0.887
escextra sexcombs0.887
dallydivision abnormally delayed0.885
Su(H)Suppressor of Hairless0.885
Su(var)205Suppressor of variegation 2050.881
PclPolycomblike0.881
Hel25EHelicase at 25E0.879
par-1CG8201 gene product from transcript CG8201-RA0.875
gsbgooseberry0.866
Dsp1Dorsal switch protein 10.861
tshteashirt0.861
pr-set7CG3307 gene product from transcript CG3307-RC0.858
nubnubbin0.854
dshdishevelled0.854
Doc2Dorsocross20.853
NNotch0.850
CTCFCG8591 gene product from transcript CG8591-RA0.845
HLHmdeltaE(spl) region transcript mdelta0.832
aopanterior open0.827
RgaRegena0.826
MED6Mediator complex subunit 60.825
emsempty spiracles0.825
crmcramped0.822
TrlTrithorax-like0.816
knknot0.795
Src42ASrc oncogene at 42A0.793
nabCG33545 gene product from transcript CG33545-RC0.788
JraJun-related antigen0.786
osaCG7467 gene product from transcript CG7467-RD0.785
spensplit ends0.783
kibrakibra ortholog0.781
MedMedea0.781
slouslouch0.776
snasnail0.771
dppdecapentaplegic0.771
bcdbicoid0.771
Acf1ATP-dependent chromatin assembly factor large subunit0.768
BRWD3CG31132 gene product from transcript CG31132-RA0.767
alaristaless0.766
OptixCG18455 gene product from transcript CG18455-RA0.753
ushu-shaped0.745
slmbsupernumerary limbs0.744
mammastermind0.729
Trf2TATA box binding protein-related factor 20.721
E(var)3-9Enhancer of variegation 3-90.721
Tip60CG6121 gene product from transcript CG6121-RA0.713
PtenCG5671 gene product from transcript CG5671-RB0.712
eyaeyes absent0.707
Rho1CG8416 gene product from transcript CG8416-RB0.706
Kr-h1Kruppel homolog 10.702
vasvasa0.698
CycBCyclin B0.695
KrKruppel0.694
enokenoki mushroom0.691
Ced-12CG5336 gene product from transcript CG5336-RA0.689
G9aCG2995 gene product from transcript CG2995-RA0.686
tintinman0.684
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Dusp1dual specificity phosphatase 10.815
JunJun oncogene0.724
Il8rbinterleukin 8 receptor, beta0.699
Id1inhibitor of DNA binding 10.596
Tgfbr2transforming growth factor, beta receptor II0.581
Tcfe2atranscription factor E2a0.556
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.546
Junbjun B proto-oncogene0.542
Nfibnuclear factor I/B0.541
FosFBJ osteosarcoma oncogene0.528
DbpD site of albumin promoter (albumin D-box) binding protein0.517
Hoxc4homeo box C40.483
Klf4Kruppel-like factor 4 (gut)0.467
Dchs1dachsous 1 (Drosophila)0.456
Arf6ADP-ribosylation factor 60.432
Creb1cAMP responsive element binding protein 10.424
Ier2immediate early response 20.415
Nek9NIMA (never in mitosis gene a)- related kinase 90.406
Dusp6dual specificity phosphatase 60.393
Ppp2cbprotein phosphatase 2, catalytic subunit, beta isoform0.382
Rhobras homolog gene family, member B0.366
Hnrnprheterogeneous nuclear ribonucleoprotein R0.360
Shhsonic hedgehog0.348
Anxa2annexin A20.348
Trim28tripartite motif-containing 280.345
Hnrpdheterogeneous nuclear ribonucleoprotein D0.345
Prss3protease, serine, 30.343
Flt1FMS-related tyrosine kinase 10.332
Nfianuclear factor I/A0.326
Smad3SMAD family member 30.325
Nr2f2nuclear receptor subfamily 2, group F, member 20.318
Nedd4neural precursor cell expressed, developmentally down-regulated 40.314
Btg2BTG family, member 20.311
Cysscystatin S0.308
Gabbr1gamma-aminobutyric acid (GABA) B receptor 10.307
Khdrbs1KH domain containing, RNA binding, signal transduction associated 10.306
S100a8S100 calcium binding protein A80.304
Casp2caspase 20.302
Zfp36zinc finger protein 360.299
Smad7SMAD family member 70.296
Egr1early growth response 10.295
Tmpothymopoietin0.295
Pde4bphosphodiesterase 4B, cAMP specific0.284
Synposynaptopodin0.283
Hdac2histone deacetylase 20.282
S100a9S100 calcium binding protein A90.281
Dab2disabled homolog 2 (Drosophila)0.278
Ptmaprothymosin alpha0.274
Nr1d2nuclear receptor subfamily 1, group D, member 20.274
Sfrs1splicing factor, arginine/serine-rich 10.273
Wbp11WW domain binding protein 110.267
Syt2synaptotagmin II0.255
Kcnt1potassium channel, subfamily T, member 10.254
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.250
Lifleukemia inhibitory factor0.250
Sfrs2splicing factor, arginine/serine-rich 20.247
Klf2Kruppel-like factor 2 (lung)0.246
SetSET nuclear oncogene0.244
Ascl1achaete-scute complex homolog 1 (Drosophila)0.243
Igfbp5insulin-like growth factor binding protein 50.242
Vimvimentin0.242
Cd9CD9 molecule0.239
FynFYN oncogene related to SRC, FGR, YES0.237
Mgpmatrix Gla protein0.236
Galr2galanin receptor 20.236
Pcnaproliferating cell nuclear antigen0.234
Sgk1serum/glucocorticoid regulated kinase 10.234
Prrx1paired related homeobox 10.230
Mllt4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.228
Lnpepleucyl/cystinyl aminopeptidase0.228
Purbpurine rich element binding protein B0.227
Ddx39DEAD (Asp-Glu-Ala-Asp) box polypeptide 390.227
Stip1stress-induced phosphoprotein 10.225
Vom2r27vomeronasal 2 receptor, 270.224
Hand2heart and neural crest derivatives expressed 20.221
Foxd1forkhead box D10.219
Trim47tripartite motif-containing 470.218
Mycmyelocytomatosis oncogene0.218
Cd247Cd247 molecule0.217
Zranb2zinc finger, RAN-binding domain containing 20.216
Calm2calmodulin 20.213
Dynll1dynein light chain LC8-type 10.212
Grk1G protein-coupled receptor kinase 10.211
Ptpn1protein tyrosine phosphatase, non-receptor type 10.210
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.210
Nr3c1nuclear receptor subfamily 3, group C, member 10.208
Sdc3syndecan 30.208
RorbRAR-related orphan receptor B0.207
Metmet proto-oncogene0.206
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.203
CrebbpCREB binding protein0.202
Arl9ADP-ribosylation factor-like 90.202
Anxa1annexin A10.201
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.201
Socs3suppressor of cytokine signaling 30.199
Hmgb1high mobility group box 10.198
Fabp1fatty acid binding protein 1, liver0.198
Sox18SRY (sex determining region Y)-box 180.197
Thbdthrombomodulin0.196
Hfehemochromatosis0.195