The network for 'positive regulation of lipid catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of lipid catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.

NameDescriptionProbabilityFunc Analog Organism
MIG1Mig1p0.241
MIG2Mig2p0.235
PIP2Pip2p0.153
CSR2Csr2p0.128
HAL5Hal5p0.115
FAA2Faa2p0.092
CBK1Cbk1p0.086
LYS5Lys5p0.084
SWI1Swi1p0.076
YKR075Chypothetical protein0.075
OAF1Oaf1p0.074
MIG3Mig3p0.071
RPN4Rpn4p0.065
YPL014Whypothetical protein0.064
SNF5Snf5p0.061
VAC7Vac7p0.059
GLN3Gln3p0.058
HXT3Hxt3p0.054
PXA1Pxa1p0.054
NRG1Nrg1p0.053
ACS1Acs1p0.052
MBR1Mbr1p0.051
MOT3Mot3p0.051
SNF3Snf3p0.046
DAL81Dal81p0.045
TOS3Tos3p0.045
TBS1Tbs1p0.044
SAK1Sak1p0.044
BEM3Bem3p0.043
HPA2Hpa2p0.043
GYL1Gyl1p0.041
ROD1Rod1p0.041
RGS2Rgs2p0.040
ARP8Arp8p0.040
PEX5Pex5p0.038
GIP2Gip2p0.038
RDS2Rds2p0.038
PHO12Pho12p0.038
VPS27Vps27p0.038
GAT2Gat2p0.037
POG1Pog1p0.036
AFT1Aft1p0.036
YKR096Whypothetical protein0.036
AVO1Avo1p0.035
ICS2Ics2p0.035
PUT1Put1p0.035
SRD1Srd1p0.034
STP1Stp1p0.034
RPI1Rpi1p0.034
HHO1Hho1p0.034
ATG29Atg29p0.034
TRA1Tra1p0.034
CUP9Cup9p0.034
YHR202Whypothetical protein0.033
KIC1Kic1p0.033
CTI6Cti6p0.032
IRC23Irc23p0.032
YDL218Whypothetical protein0.032
AGC1Agc1p0.031
WAR1War1p0.031
SKS1Sks1p0.031
PUT4Put4p0.031
VID24Vid24p0.030
YLR264C-Ahypothetical protein0.030
PTI1Pti1p0.030
XYL2Xyl2p0.030
LEU2Leu2p0.030
SBE22Sbe22p0.030
YOL038C-Ahypothetical protein0.030
RTG3Rtg3p0.030
YAR068Whypothetical protein0.030
PAH1Pah1p0.030
PDR10Pdr10p0.030
TIP1Tip1p0.029
YLR162Whypothetical protein0.029
ZAP1Zap1p0.029
YPR157Whypothetical protein0.029
HOR2Hor2p0.029
YIR035Chypothetical protein0.029
YNL234Whypothetical protein0.028
PCL8Pcl8p0.028
YAK1Yak1p0.028
NTO1Nto1p0.028
GDH3Gdh3p0.028
SSU1Ssu1p0.028
YKL187Chypothetical protein0.028
ARP10Arp10p0.028
YNL295Whypothetical protein0.027
ADR1Adr1p0.027
MET4Met4p0.027
SSP1Ssp1p0.027
CUP1-1Cup1-1p0.027
GIS4Gis4p0.027
YDR124Whypothetical protein0.027
SPL2Spl2p0.027
CAK1Cak1p0.026
PRM4Prm4p0.026
PCT1Pct1p0.026
ACE2Ace2p0.026
TYE7Tye7p0.026
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
pomcaproopiomelanocortin a0.728
tshbthyroid stimulating hormone, beta subunit0.182
prlprolactin0.175
pou1f1POU domain, class 1, transcription factor 10.110
fshbfollicle stimulating hormone, beta polypeptide0.103
cgaglycoprotein hormones, alpha polypeptide0.055
ildr1bimmunoglobulin-like domain containing receptor 1b0.050
tymsthymidylate synthase0.034
dync1h1dynein, cytoplasmic 1, heavy chain 10.032
si:ch211-233a1.8si:ch211-233a1.80.025
pgm1phosphoglucomutase 10.025
smg7Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)0.024
srfserum response factor0.020
nr1i2nuclear receptor subfamily 1, group I, member 20.018
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.017
ptprfprotein tyrosine phosphatase, receptor type, F0.017
ifnphi1interferon phi 10.016
il8interleukin 80.016
setd5SET domain containing 50.015
zgc:112180zgc:1121800.014
tnfatumor necrosis factor a (TNF superfamily, member 2)0.014
zgc:92648zgc:926480.014
bglapbone gamma-carboxyglutamate (gla) protein0.013
wdhd1WD repeat and HMG-box DNA binding protein 10.013
zgc:112986zgc:1129860.013
orc6origin recognition complex, subunit 60.013
sardhsarcosine dehydrogenase0.012
foxn4forkhead box N40.012
skianuclear oncoprotein skia0.010
csf3rcolony stimulating factor 3 receptor (granulocyte)0.010
nadl1.2neural adhesion molecule L1.20.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
InRInsulin-like receptor0.875
S6kRPS6-p70-protein kinase0.650
dmdiminutive0.362
dapdacapo0.322
Pi3K92ECG4141 gene product from transcript CG4141-RB0.283
Pk61CProtein kinase 61C0.275
panpangolin0.252
Cdk4Cyclin-dependent kinase 40.230
Akt1CG4006 gene product from transcript CG4006-RA0.195
hipkhomeodomain interacting protein kinase0.105
ThorCG8846 gene product from transcript CG8846-RA0.080
Lk6CG17342 gene product from transcript CG17342-RA0.077
foxoforkhead box, sub-group O0.074
aldaltered disjunction0.070
CycJCyclin J0.067
cdc2cCG10498 gene product from transcript CG10498-RC0.063
Src64BSrc oncogene at 64B0.061
Ilp6Insulin-like peptide 60.059
CycDCyclin D0.059
RPA2Replication protein A20.049
Sirt2CG5085 gene product from transcript CG5085-RA0.048
Zasp52Z band alternatively spliced PDZ-motif protein 520.045
HLH106Helix loop helix protein 1060.044
ImpL2Ecdysone-inducible gene L20.037
SAKSak kinase0.032
mubmushroom-body expressed0.029
pathpathetic0.028
PtenCG5671 gene product from transcript CG5671-RB0.028
CG4973CG4973 gene product from transcript CG4973-RA0.026
GRHRGonadotropin-releasing hormone receptor0.026
MrtfMyocardin-related transcription factor0.025
tldtolloid0.024
NrgNeuroglian0.024
hppyhappyhour0.023
konkon-tiki0.023
scylscylla0.022
bynbrachyenteron0.022
CycHCyclin H0.021
hephhephaestus0.021
dhddeadhead0.021
sflsulfateless0.020
Mef2Myocyte enhancer factor 20.019
CG16926CG16926 gene product from transcript CG16926-RA0.019
squsquash0.019
nejnejire0.019
Obp99cOdorant-binding protein 99c0.018
gemininCG3183 gene product from transcript CG3183-RA0.018
VAChTCG32848 gene product from transcript CG32848-RA0.017
MntCG13316 gene product from transcript CG13316-RD0.017
Df31Decondensation factor 310.017
LnkCG17367 gene product from transcript CG17367-RC0.017
piepineapple eye0.016
MED20Mediator complex subunit 200.016
GLazGlial Lazarillo0.016
srstripe0.015
stumpsCG31317 gene product from transcript CG31317-RC0.015
ribribbon0.015
CG9752CG9752 gene product from transcript CG9752-RA0.015
PRL-1CG4993 gene product from transcript CG4993-RB0.014
bskbasket0.014
CG5840CG5840 gene product from transcript CG5840-RB0.014
Stat92ESignal-transducer and activator of transcription protein at 92E0.014
CG9740CG9740 gene product from transcript CG9740-RA0.014
ruxroughex0.014
CG4673CG4673 gene product from transcript CG4673-RB0.014
CG5731CG5731 gene product from transcript CG5731-RA0.013
GstS1Glutathione S transferase S10.013
CG9548CG9548 gene product from transcript CG9548-RA0.013
HcfHost cell factor0.013
AtpalphaNa pump alpha subunit0.013
Vap-33-1CG5014 gene product from transcript CG5014-RB0.013
vrivrille0.013
drkdownstream of receptor kinase0.012
HipHopHP1-HOAP-interacting protein0.012
pippipe0.012
ttvtout-velu0.011
Eip63EEcdysone-induced protein 63E0.011
CG9772CG9772 gene product from transcript CG9772-RB0.011
dmtdalmatian0.011
bmmbrummer0.011
zfh1Zn finger homeodomain 10.011
RhoGAP68FCG6811 gene product from transcript CG6811-RA0.011
mysmyospheroid0.010
Cks30ACyclin-dependent kinase subunit 30A0.010
E2f2E2F transcription factor 20.010
shnschnurri0.010
tomosynCG17762 gene product from transcript CG17762-RB0.010
His2AvHistone H2A variant0.010
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
INSRinsulin receptor0.920
CDK2cyclin-dependent kinase 20.798
ALBalbumin0.705
PRKCZprotein kinase C, zeta0.650
NOXA1NADPH oxidase activator 10.506
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.472
SETD8SET domain containing (lysine methyltransferase) 80.299
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.270
IL1R1interleukin 1 receptor, type I0.264
GRB10growth factor receptor-bound protein 100.233
CCNA2cyclin A20.216
NCF1neutrophil cytosolic factor 10.208
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.184
MAFAv-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)0.151
FGAfibrinogen alpha chain0.122
IL1RAPinterleukin 1 receptor accessory protein0.087
NCF2neutrophil cytosolic factor 20.081
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.079
CRPC-reactive protein, pentraxin-related0.077
PEX19peroxisomal biogenesis factor 190.074
CCNE1cyclin E10.071
CCNB2cyclin B20.048
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.047
CDK1cyclin-dependent kinase 10.046
IRS1insulin receptor substrate 10.045
CCDC115coiled-coil domain containing 1150.043
ZNF71zinc finger protein 710.043
SKP2S-phase kinase-associated protein 2 (p45)0.038
IGF1Rinsulin-like growth factor 1 receptor0.037
GATA2GATA binding protein 20.036
PRKCAprotein kinase C, alpha0.034
BRAFv-raf murine sarcoma viral oncogene homolog B10.034
SH3RF1SH3 domain containing ring finger 10.033
APOA1apolipoprotein A-I0.032
APOC3apolipoprotein C-III0.031
CCNB1cyclin B10.029
LCATlecithin-cholesterol acyltransferase0.028
F11RF11 receptor0.027
NUMBnumb homolog (Drosophila)0.025
TAL1T-cell acute lymphocytic leukemia 10.025
CCL14chemokine (C-C motif) ligand 140.024
IL1RNinterleukin 1 receptor antagonist0.023
PRKCBprotein kinase C, beta0.022
APOC1apolipoprotein C-I0.022
CYBAcytochrome b-245, alpha polypeptide0.022
SIRT1sirtuin 10.022
UBE2R2ubiquitin-conjugating enzyme E2R 20.021
PGRMC1progesterone receptor membrane component 10.020
CDCP1CUB domain containing protein 10.020
RARAretinoic acid receptor, alpha0.019
IRS2insulin receptor substrate 20.018
RUNX1runt-related transcription factor 10.017
GATA1GATA binding protein 1 (globin transcription factor 1)0.017
CXCL2chemokine (C-X-C motif) ligand 20.017
ITGB5integrin, beta 50.017
PTPN6protein tyrosine phosphatase, non-receptor type 60.016
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.016
GATA4GATA binding protein 40.016
APOBapolipoprotein B (including Ag(x) antigen)0.016
TNFRSF10Ctumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain0.015
PTPN5protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)0.015
SHC1SHC (Src homology 2 domain containing) transforming protein 10.015
LRP1low density lipoprotein receptor-related protein 10.014
LATlinker for activation of T cells0.014
PEX14peroxisomal biogenesis factor 140.014
PTPN1protein tyrosine phosphatase, non-receptor type 10.013
APOA2apolipoprotein A-II0.013
DLG1discs, large homolog 1 (Drosophila)0.013
ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 10.013
PIK3CAphosphoinositide-3-kinase, catalytic, alpha polypeptide0.012
PICK1protein interacting with PRKCA 10.012
ABCD1ATP-binding cassette, sub-family D (ALD), member 10.011
MAPTmicrotubule-associated protein tau0.011
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.011
PEX3peroxisomal biogenesis factor 30.011
PEX11Bperoxisomal biogenesis factor 11 beta0.010
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.010
SH2B1SH2B adaptor protein 10.010
TCF12transcription factor 120.010
LMO2LIM domain only 2 (rhombotin-like 1)0.010
STAT5Bsignal transducer and activator of transcription 5B0.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Pnpla2patatin-like phospholipase domain containing 21.000
Lepleptin0.998
Ghrgrowth hormone receptor0.995
Ldb3LIM domain binding 30.982
Ppargperoxisome proliferator activated receptor gamma0.941
Kiss1KiSS-1 metastasis-suppressor0.711
Nos3nitric oxide synthase 3, endothelial cell0.660
Lpin1lipin 10.604
Lhx3LIM homeobox protein 30.568
Il1binterleukin 1 beta0.467
Actn2actinin alpha 20.461
Cdkn1bcyclin-dependent kinase inhibitor 1B0.455
Cideccell death-inducing DFFA-like effector c0.427
Il1ainterleukin 1 alpha0.359
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.352
Abhd5abhydrolase domain containing 50.330
Ccna2cyclin A20.295
Cav1caveolin 1, caveolae protein0.249
Irs1insulin receptor substrate 10.216
Leprleptin receptor0.209
Prkceprotein kinase C, epsilon0.208
Insrinsulin receptor0.174
Adrb3adrenergic receptor, beta 30.154
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.126
Esr1estrogen receptor 1 (alpha)0.125
Plcd1phospholipase C, delta 10.080
Akt1thymoma viral proto-oncogene 10.069
Irs2insulin receptor substrate 20.067
Ncoa3nuclear receptor coactivator 30.064
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.063
Mark2MAP/microtubule affinity-regulating kinase 20.057
Clockcircadian locomotor output cycles kaput0.055
Gpd2glycerol phosphate dehydrogenase 2, mitochondrial0.052
Npc1Niemann Pick type C10.051
Arandrogen receptor0.044
Ccne1cyclin E10.041
Lrp1low density lipoprotein receptor-related protein 10.038
Cdk4cyclin-dependent kinase 40.037
Il1r1interleukin 1 receptor, type I0.034
Apoeapolipoprotein E0.034
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.033
Tnftumor necrosis factor0.029
Thrathyroid hormone receptor alpha0.029
Zfp592zinc finger protein 5920.026
Asprv1aspartic peptidase, retroviral-like 10.023
Plin5perilipin 50.023
Prkacaprotein kinase, cAMP dependent, catalytic, alpha0.018
Prlrprolactin receptor0.015
Il1rninterleukin 1 receptor antagonist0.015
F10coagulation factor X0.015
H1histocompatibility 10.015
Nhlh2nescient helix loop helix 20.015
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.014
Irg1immunoresponsive gene 10.013
Cxcl2chemokine (C-X-C motif) ligand 20.013
SrcRous sarcoma oncogene0.013
Fpr1formyl peptide receptor 10.013
Irak4interleukin-1 receptor-associated kinase 40.013
Lipelipase, hormone sensitive0.011
Bglapbone gamma carboxyglutamate protein0.011
Tnfrsf13btumor necrosis factor receptor superfamily, member 13b0.011
Mknk2MAP kinase-interacting serine/threonine kinase 20.011
Ptpn22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.011
Niacr1niacin receptor 10.011
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Acot2acyl-CoA thioesterase 20.300
Cd36CD36 molecule (thrombospondin receptor)0.175
Cpt2carnitine palmitoyltransferase 20.139
Hist1h1ahistone cluster 1, H1a0.136
Racgap1Rac GTPase-activating protein 10.129
Prdm2PR domain containing 2, with ZNF domain0.108
Mcm6minichromosome maintenance complex component 60.101
Top2atopoisomerase (DNA) II alpha0.091
Gpamglycerol-3-phosphate acyltransferase, mitochondrial0.089
Angptl4angiopoietin-like 40.089
Mtus1mitochondrial tumor suppressor 10.080
Cpt1bcarnitine palmitoyltransferase 1b, muscle0.075
Nr0b2nuclear receptor subfamily 0, group B, member 20.072
Catcatalase0.071
Hmgcs23-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)0.070
RGD1308772similar to KIAA0564 protein0.069
Slc27a1solute carrier family 27 (fatty acid transporter), member 10.068
Gpd1glycerol-3-phosphate dehydrogenase 1 (soluble)0.064
Camk2gcalcium/calmodulin-dependent protein kinase II gamma0.062
Aqp7aquaporin 70.058
Acadlacyl-Coenzyme A dehydrogenase, long-chain0.058
Tcfe2atranscription factor E2a0.057
Acadmacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain0.056
Idh1isocitrate dehydrogenase 1 (NADP+), soluble0.056
Syngr2synaptogyrin 20.051
Eci1enoyl-Coenzyme A delta isomerase 10.051
Ghrgrowth hormone receptor0.051
Atp2b3ATPase, Ca++ transporting, plasma membrane 30.047
Eps15epidermal growth factor receptor pathway substrate 150.041
Hmgb2high mobility group box 20.041
Dgat2diacylglycerol O-acyltransferase homolog 2 (mouse)0.039
Nfianuclear factor I/A0.037
Traf4af1TRAF4 associated factor 10.037
Stmn1stathmin 10.036
Cideacell death-inducing DFFA-like effector a0.035
Impa2inositol (myo)-1(or 4)-monophosphatase 20.033
Hadhahydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit0.032
SnrkSNF related kinase0.032
Fgfr1Fibroblast growth factor receptor 10.032
Cyp3a23/3a1cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 10.032
Amy2amylase 2, pancreatic0.032
Tff3trefoil factor 3, intestinal0.032
Dgat1diacylglycerol O-acyltransferase homolog 1 (mouse)0.031
Agpat21-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)0.031
Acox1acyl-Coenzyme A oxidase 1, palmitoyl0.031
Etfdhelectron-transferring-flavoprotein dehydrogenase0.030
Atp1a2ATPase, Na+/K+ transporting, alpha 2 polypeptide0.030
Ccne1cyclin E10.030
Pttg1pituitary tumor-transforming 10.029
Ccnd3cyclin D30.028
PbkPDZ binding kinase0.028
Vamp1vesicle-associated membrane protein 10.028
Tbrg4transforming growth factor beta regulator 40.028
Baatbile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)0.027
Myo1cmyosin IC0.026
Apoa2apolipoprotein A-II0.025
Nntnicotinamide nucleotide transhydrogenase0.025
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.024
Oclnoccludin0.024
Smc4structural maintenance of chromosomes 40.023
Ehhadhenoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase0.023
Pcnaproliferating cell nuclear antigen0.023
Prb1proline-rich protein BstNI subfamily 10.023
Cmtm6CKLF-like MARVEL transmembrane domain containing 60.023
Hbp1HMG-box transcription factor 10.023
Tmem120atransmembrane protein 120A0.022
Ezrezrin0.022
Rbp2retinol binding protein 2, cellular0.022
Lin7blin-7 homolog b (C. elegans)0.021
Mosc1MOCO sulphurase C-terminal domain containing 10.021
Mki67antigen identified by monoclonal antibody Ki-670.021
Cks2CDC28 protein kinase regulatory subunit 20.021
Prkaa2protein kinase, AMP-activated, alpha 2 catalytic subunit0.021
Cdkn3cyclin-dependent kinase inhibitor 30.021
Pex11aperoxisomal biogenesis factor 11 alpha0.021
Acot1acyl-CoA thioesterase 10.021
Casp3caspase 30.021
Ryr2ryanodine receptor 2, cardiac0.021
Aifm3apoptosis-inducing factor, mitochondrion-associated 30.020
Lipalipase A, lysosomal acid, cholesterol esterase0.020
Maptmicrotubule-associated protein tau0.020
Abcg4ATP-binding cassette, subfamily G (WHITE), member 40.020
Bat5HLA-B associated transcript 50.020
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.020
Pdia4protein disulfide isomerase family A, member 40.020
Pnpla2patatin-like phospholipase domain containing 20.020
Albalbumin0.020
Agtr1aangiotensin II receptor, type 1a0.019
Cox8bcytochrome c oxidase, subunit VIIIb0.019
Mgllmonoglyceride lipase0.019
Ephx2epoxide hydrolase 2, cytoplasmic0.019
Pex19peroxisomal biogenesis factor 190.019
Ccnb1cyclin B10.019
LOC259246alpha-2u globulin PGCL10.019
Pcyt1aphosphate cytidylyltransferase 1, choline, alpha0.019
Emp1epithelial membrane protein 10.018
RGD1302996hypothetical protein MGC:158540.018
Fn3kfructosamine 3 kinase0.018
Sdc1syndecan 10.018
Prim1DNA primase, p49 subunit0.018