The network for 'aromatic amino acid family metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

aromatic amino acid family metabolic process

The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).

NameDescriptionProbabilityFunc Analog Organism
TRP2Trp2p0.818
HOM2Hom2p0.480
ARO9Aro9p0.365
ARO10Aro10p0.256
TRP3Trp3p0.230
GND1Gnd1p0.221
HIS4His4p0.197
ARO8Aro8p0.173
YDL157Chypothetical protein0.125
PDC5Pdc5p0.118
TRP4Trp4p0.103
TRP5Trp5p0.093
ILV1Ilv1p0.070
HMX1Hmx1p0.066
VMA13Vma13p0.055
GYL1Gyl1p0.053
YBR296C-Ahypothetical protein0.045
LSB6Lsb6p0.040
ARG2Arg2p0.039
ARO3Aro3p0.039
CAB1Cab1p0.039
ASN2Asn2p0.036
ERT1Ert1p0.036
THR4Thr4p0.035
YLR264C-Ahypothetical protein0.033
GGC1Ggc1p0.033
SRD1Srd1p0.032
ARO1Aro1p0.031
YOL038C-Ahypothetical protein0.029
ENA5Ena5p0.028
ACF4Acf4p0.028
YLR162Whypothetical protein0.028
BIO2Bio2p0.027
OYE2Oye2p0.027
FAS1Fas1p0.027
SOL3Sol3p0.026
YAR068Whypothetical protein0.026
ARP10Arp10p0.026
UBP7Ubp7p0.026
YJR061Whypothetical protein0.025
YPL199Chypothetical protein0.025
AAP1Aap1p0.025
PDC1Pdc1p0.025
SER2Ser2p0.024
MET8Met8p0.024
YPR157Whypothetical protein0.024
VMA3Vma3p0.024
PRO2Pro2p0.024
JLP2Jlp2p0.024
LEU2Leu2p0.024
MER1Mer1p0.023
TYR1Tyr1p0.023
SRX1Srx1p0.023
URA4Ura4p0.023
FCY21Fcy21p0.022
ATP6Atp6p0.022
YLR042Chypothetical protein0.022
CUP1-1Cup1-1p0.022
HIS7His7p0.022
CHA1Cha1p0.022
CTM1Ctm1p0.022
URA3Ura3p0.021
HXT3Hxt3p0.021
YBR013Chypothetical protein0.021
PHO86Pho86p0.021
YAR066Whypothetical protein0.021
ZPS1Zps1p0.021
CUE2Cue2p0.021
DPS1Dps1p0.020
HOM6Hom6p0.020
YKL033W-Ahypothetical protein0.020
HPF1Hpf1p0.020
SDT1Sdt1p0.020
FIT2Fit2p0.019
YER186Chypothetical protein0.019
YLR278Chypothetical protein0.019
BNA4Bna4p0.019
ADE12Ade12p0.019
AUA1Aua1p0.019
BAT2Bat2p0.019
SWC7Swc7p0.019
YOL013W-Ahypothetical protein0.019
GRX3Grx3p0.019
COT1Cot1p0.018
HOM3Hom3p0.018
YLR040Chypothetical protein0.018
SPL2Spl2p0.018
ADH6Adh6p0.018
UPS3Ups3p0.018
MF(ALPHA)2Mf(alpha)2p0.018
FAU1Fau1p0.018
FMT1Fmt1p0.017
AAD15Aad15p0.017
HIS3His3p0.017
YAL037C-Ahypothetical protein0.017
CPD1Cpd1p0.017
DIC1Dic1p0.017
PTR2Ptr2p0.017
TSC3Tsc3p0.017
FRE7Fre7p0.017
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
mitfamicrophthalmia-associated transcription factor a0.962
sox10SRY-box containing gene 100.797
slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.522
kitakit receptor a0.418
dctdopachrome tautomerase0.307
thtyrosine hydroxylase0.225
slc45a2solute carrier family 45, member 20.176
pmelapremelanosome protein a0.163
ednrb1endothelin receptor B0.111
csf1racolony stimulating factor 1 receptor, a0.069
vps39vacuolar protein sorting 39 homolog (S. cerevisiae)0.069
cyp19a1bcytochrome P450, family 19, subfamily A, polypeptide 1b0.068
per2period homolog 2 (Drosophila)0.047
ltkleukocyte tyrosine kinase0.043
tbx20T-box 200.038
pnp4apurine nucleoside phosphorylase 4a0.035
lhx2bLIM homeobox 2b0.033
slc24a5solute carrier family 24, member 50.033
tyrp1tyrosinase-related protein 10.032
tyrtyrosinase0.031
rhorhodopsin0.029
nos1nitric oxide synthase 1 (neuronal)0.028
fevFEV (ETS oncogene family)0.026
prom1bprominin 1 b0.026
atoh7atonal homolog 70.026
tyrp1btyrosinase-related protein 1b0.026
tph2tryptophan hydroxylase 2 (tryptophan 5-monooxygenase)0.025
lmx1b.1LIM homeobox transcription factor 1, beta 10.025
dlx2adistal-less homeobox gene 2a0.024
cnr1cannabinoid receptor 10.022
dlg1discs, large (Drosophila) homolog 10.022
nr4a2bnuclear receptor subfamily 4, group A, member 2b0.021
ptch1patched 10.021
wu:fj82b07wu:fj82b070.021
mpp5amembrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)0.020
si:dkeyp-59a8.4si:dkeyp-59a8.40.019
mtpmicrosomal triglyceride transfer protein0.019
zgc:112329zgc:1123290.019
slc6a4asolute carrier family 6 (neurotransmitter transporter, serotonin), member 4A0.019
lmx1b.2LIM homeobox transcription factor 1, beta 20.018
ddcdopa decarboxylase0.017
nme4non-metastatic cells 4, protein expressed in0.017
ucp1uncoupling protein 10.017
esr2bestrogen receptor 2b0.016
col9a2procollagen, type IX, alpha 20.016
zgc:100919zgc:1009190.015
gpr126G protein-coupled receptor 1260.015
edn1endothelin 10.015
htr1aa5-hydroxytryptamine (serotonin) receptor 1A a0.014
maomonoamine oxidase0.014
trpm7transient receptor potential cation channel, subfamily M, member 70.014
ncam1bneural cell adhesion molecule 1b0.014
lhx8aLIM homeobox 8a0.014
tac1tachykinin 10.013
wt1awilms tumor 1a0.013
gnrh3gonadotropin-releasing hormone 30.013
th2tyrosine hydroxylase 20.013
esr1estrogen receptor 10.013
aox3aldehyde oxidase 30.012
fgf10afibroblast growth factor 10a0.012
tfectranscription factor EC0.012
dbhdopamine beta hydroxylase0.012
phox2bpaired-like homeobox 2b0.011
rag1recombination activating gene 10.011
esr2aestrogen receptor 2a0.011
pcp4aPurkinje cell protein 4a0.011
uts1urotensin 10.011
prox1prospero-related homeobox gene 10.011
bmp2abone morphogenetic protein 2a0.011
foxl1forkhead box L10.011
ascl1aachaete-scute complex-like 1a (Drosophila)0.010
per3period homolog 3 (Drosophila)0.010
cadm2acell adhesion molecule 2a0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
plepale0.635
PuPunch0.296
eebony0.149
vvermilion0.120
rbruby0.069
kkvkrotzkopf verkehrt0.063
inx2innexin 20.056
HnHenna0.053
PapssPAPS synthetase0.048
uifuninflatable0.039
pplpumpless0.036
bynbrachyenteron0.032
parkparkin0.032
VmatVesicular monoamine transporter0.029
ltdlightoid0.027
ShawShaker cognate w0.025
sesepia0.025
TbhTyramine beta hydroxylase0.025
molmoladietz0.024
Spn77BaSerpin 77Ba0.024
ClkClock0.023
bnlbranchless0.023
sevsevenless0.022
TrpA1Transient receptor potential A10.021
obst-Aobstructor-A0.021
HmgcrHMG Coenzyme A reductase0.021
Hr46Hormone receptor-like in 460.021
CG17325CG17325 gene product from transcript CG17325-RA0.020
CG3239CG3239 gene product from transcript CG3239-RB0.020
srstripe0.020
ade3adenosine 30.020
Ctr1ACopper transporter 1A0.019
Ost48Oligosaccharyltransferase 48kD subunit0.018
omdoocyte maintenance defects0.018
pugpugilist0.017
CG11347CG11347 gene product from transcript CG11347-RE0.017
CG10570CG10570 gene product from transcript CG10570-RA0.017
Mmp1Matrix metalloproteinase 10.017
DdcDopa decarboxylase0.016
DNaseIIDeoxyribonuclease II0.016
ATP7CG1886 gene product from transcript CG1886-RB0.015
esgescargot0.015
ttan0.015
pdfrPDF receptor0.015
Mlp84BMuscle LIM protein at 84B0.015
Tps1Trehalose-6-phosphate synthase 10.015
cpocouch potato0.015
PdfPigment-dispersing factor0.015
painpainless0.014
CCSCG17753 gene product from transcript CG17753-RA0.014
knkknickkopf0.014
smsmooth0.014
NPFR1neuropeptide F receptor0.014
CG9649CG9649 gene product from transcript CG9649-RA0.014
necnecrotic0.014
IdhIsocitrate dehydrogenase0.014
Pcdpterin-4a-carbinolamine dehydratase0.013
hgohomogentisate 1,2-dioxygenase0.013
CG16778CG16778 gene product from transcript CG16778-RA0.013
Sp7Serine protease 70.013
TimpTissue inhibitor of metalloproteases0.013
nimB5nimrod B50.013
hughugin0.012
npfneuropeptide F0.012
moimodigliani0.012
CG12325CG12325 gene product from transcript CG12325-RA0.012
karkarmoisin0.012
crccryptocephal0.012
Hex-CHexokinase C0.011
Cht2Chitinase 20.011
nanarrow abdomen0.011
Cyp4ac1CG14032 gene product from transcript CG14032-RA0.011
Or83bOdorant receptor 83b0.011
Nf1Neurofibromin 10.011
vermvermiform0.010
CG2224CG2224 gene product from transcript CG2224-RA0.010
CG6503CG6503 gene product from transcript CG6503-RA0.010
Saf-BScaffold attachment factor B0.010
bursbursicon0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PDZD11PDZ domain containing 110.997
CXCL10chemokine (C-X-C motif) ligand 100.158
CXCL11chemokine (C-X-C motif) ligand 110.064
SLC2A2solute carrier family 2 (facilitated glucose transporter), member 20.037
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.029
MBL2mannose-binding lectin (protein C) 2, soluble0.020
CXCL9chemokine (C-X-C motif) ligand 90.017
LECT2leukocyte cell-derived chemotaxin 20.015
KNG1kininogen 10.014
NR1H4nuclear receptor subfamily 1, group H, member 40.013
LAMP3lysosomal-associated membrane protein 30.012
CTSL1cathepsin L10.012
SOD2superoxide dismutase 2, mitochondrial0.012
G6PCglucose-6-phosphatase, catalytic subunit0.012
HNF4Ahepatocyte nuclear factor 4, alpha0.012
VNN1vanin 10.011
PLGplasminogen0.011
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.010
AFMafamin0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Tyrtyrosinase0.616
Tyrp1tyrosinase-related protein 10.514
Mitfmicrophthalmia-associated transcription factor0.375
Oca2oculocutaneous albinism II0.228
Rhorhodopsin0.208
Rp1retinitis pigmentosa 1 (human)0.107
Pmelpremelanosome protein0.097
ND6NADH dehydrogenase subunit 60.092
Klklotho0.041
Crb2crumbs homolog 2 (Drosophila)0.039
Slc31a1solute carrier family 31, member 10.032
anonagouti0.031
Lystlysosomal trafficking regulator0.031
Slc24a5solute carrier family 24, member 50.030
Cps1carbamoyl-phosphate synthetase 10.028
Fbn1fibrillin 10.021
Mc1rmelanocortin 1 receptor0.019
Mlphmelanophilin0.018
Slc39a4solute carrier family 39 (zinc transporter), member 40.017
Kitkit oncogene0.017
Rab38RAB38, member of RAS oncogene family0.016
Rit2Ras-like without CAAX 20.014
Steap3STEAP family member 30.014
Cyp2b10cytochrome P450, family 2, subfamily b, polypeptide 100.013
Ednrbendothelin receptor type B0.012
Loxlysyl oxidase0.011
Hps1Hermansky-Pudlak syndrome 1 homolog (human)0.010
Nhlh1nescient helix loop helix 10.010
C9complement component 90.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Pahphenylalanine hydroxylase0.403
Tdo2tryptophan 2,3-dioxygenase0.335
Fbp1fructose-1,6-bisphosphatase 10.309
Nr1h4nuclear receptor subfamily 1, group H, member 40.279
Cbscystathionine beta synthase0.233
Acsm2acyl-CoA synthetase medium-chain family member 20.230
Slc17a1solute carrier family 17 (sodium phosphate), member 10.197
Kynukynureninase (L-kynurenine hydrolase)0.140
RGD1564865similar to 20-alpha-hydroxysteroid dehydrogenase0.136
Otcornithine carbamoyltransferase0.133
Ugt2b36UDP glucuronosyltransferase 2 family, polypeptide B360.111
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.107
Pdzk1PDZ domain containing 10.093
Cyp2c12cytochrome P450, family 2, subfamily c, polypeptide 120.087
Hpgdshematopoietic prostaglandin D synthase0.084
Dpysdihydropyrimidinase0.080
Apcsamyloid P component, serum0.077
Mc4rmelanocortin 4 receptor0.072
Slco1a1solute carrier organic anion transporter family, member 1a10.068
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.068
Adh1alcohol dehydrogenase 1 (class I)0.066
RT1-A3RT1 class I, locus A30.063
Serpina1serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10.063
Avenapoptosis, caspase activation inhibitor0.061
Hao2hydroxyacid oxidase 2 (long chain)0.061
Sult1c2sulfotransferase family, cytosolic, 1C, member 20.061
Aqp9aquaporin 90.060
Keg1kidney expressed gene 10.059
Spp2secreted phosphoprotein 20.059
Aadacarylacetamide deacetylase (esterase)0.057
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.054
Cyp4f4cytochrome P450, family 4, subfamily f, polypeptide 40.054
Cd86CD86 molecule0.054
Cyp4a10cytochrome P450, family 4, subfamily a, polypeptide 100.051
Haghhydroxyacyl glutathione hydrolase0.050
Olr1699olfactory receptor 16990.050
Azgp1alpha-2-glycoprotein 1, zinc-binding0.046
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.046
Acox2acyl-Coenzyme A oxidase 2, branched chain0.046
Fam108b1family with sequence similarity 108, member B10.045
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.041
Mtmr7myotubularin related protein 70.040
Calcrcalcitonin receptor0.039
Gys2glycogen synthase 20.039
Mromaestro0.038
Abp10annexin V-binding protein ABP-100.034
Adhfe1alcohol dehydrogenase, iron containing, 10.034
Cpn1carboxypeptidase N, polypeptide 10.033
Igfbp1insulin-like growth factor binding protein 10.031
Pus3pseudouridylate synthase 30.030
Pck1phosphoenolpyruvate carboxykinase 1 (soluble)0.030
Spink1serine peptidase inhibitor, Kazal type 10.029
Neu2sialidase 2 (cytosolic sialidase)0.029
Acsm3acyl-CoA synthetase medium-chain family member 30.029
Acy1aminoacylase 10.029
Ass1argininosuccinate synthetase 10.028
Glud1glutamate dehydrogenase 10.027
Tmem8atransmembrane protein 8A0.026
Slc22a1solute carrier family 22 (organic cation transporter), member 10.025
Akr1c14aldo-keto reductase family 1, member C140.025
Hpd4-hydroxyphenylpyruvate dioxygenase0.025
Pik3c2gphosphoinositide-3-kinase, class 2, gamma polypeptide0.024
Slc17a3solute carrier family 17 (sodium phosphate), member 30.024
Cyp2c11cytochrome P450, subfamily 2, polypeptide 110.023
Bhmtbetaine-homocysteine methyltransferase0.023
Abcc2ATP-binding cassette, subfamily C (CFTR/MRP), member 20.023
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.022
Cyb5acytochrome b5 type A (microsomal)0.021
Avpr1aarginine vasopressin receptor 1A0.021
Baatbile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)0.021
FanccFanconi anemia, complementation group C0.021
RGD1305347similar to RIKEN cDNA 2610528J110.020
Slc5a2solute carrier family 5 (sodium/glucose cotransporter), member 20.020
Mbl1mannose-binding lectin (protein A) 10.020
Ttc36tetratricopeptide repeat domain 360.019
Nat8N-acetyltransferase 80.019
Uoxurate oxidase0.018
LOC691759hypothetical protein LOC6917590.018
Hsd17b6hydroxysteroid (17-beta) dehydrogenase 60.018
Slc40a1solute carrier family 39 (iron-regulated transporter), member 10.018
P2ry14purinergic receptor P2Y, G-protein coupled, 140.018
Fh1fumarate hydratase 10.017
Ddcdopa decarboxylase (aromatic L-amino acid decarboxylase)0.017
St6gal1ST6 beta-galactosamide alpha-2,6-sialyltranferase 10.017
Upb1ureidopropionase, beta0.017
Hrghistidine-rich glycoprotein0.017
Nox4NADPH oxidase 40.017
Fn3kfructosamine 3 kinase0.017
G6pcglucose-6-phosphatase, catalytic subunit0.016
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.016
Dnase1l3deoxyribonuclease 1-like 30.016
Tattyrosine aminotransferase0.016
Ndufa8NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 80.016
Slc26a1solute carrier family 26 (sulfate transporter), member 10.015
Csn2casein beta0.015
Mat1amethionine adenosyltransferase I, alpha0.015
Procprotein C0.015
Ahsgalpha-2-HS-glycoprotein0.015
F2coagulation factor II (thrombin)0.014
Cps1carbamoyl-phosphate synthetase 10.014