Process View
The network for 'positive regulation of arp2 3 complex mediated actin nucleation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation.
Name | Description | Probability | Func Analog Organism |
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Name | Description | Probability | Func Analog Organism |
---|---|---|---|
GAS7 | growth arrest-specific 7 | 1.000 | |
NCKAP1 | NCK-associated protein 1 | 1.000 | |
ABI1 | abl-interactor 1 | 1.000 | |
ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.999 | |
FMR1 | fragile X mental retardation 1 | 0.994 | |
SOS1 | son of sevenless homolog 1 (Drosophila) | 0.950 | |
WIPF1 | WAS/WASL interacting protein family, member 1 | 0.932 | |
ABI2 | abl-interactor 2 | 0.886 | |
BAIAP2 | BAI1-associated protein 2 | 0.876 | |
NCK1 | NCK adaptor protein 1 | 0.847 | |
EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.732 | |
WASF1 | WAS protein family, member 1 | 0.709 | |
CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.664 | |
PFDN1 | prefoldin subunit 1 | 0.652 | |
CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 0.607 | |
ADAM19 | ADAM metallopeptidase domain 19 | 0.590 | |
ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.436 | |
SORBS3 | sorbin and SH3 domain containing 3 | 0.433 | |
WASF2 | WAS protein family, member 2 | 0.291 | |
RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.277 | |
ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.134 | |
PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit | 0.105 | |
ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.102 | |
FMNL1 | formin-like 1 | 0.101 | |
TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 0.095 | |
TPM4 | tropomyosin 4 | 0.081 | |
CDC34 | cell division cycle 34 homolog (S. cerevisiae) | 0.052 | |
C3orf10 | chromosome 3 open reading frame 10 | 0.047 | |
HOMER3 | homer homolog 3 (Drosophila) | 0.039 | |
MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.038 | |
ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.036 | |
PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.034 | |
PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.033 | |
ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.032 | |
WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.025 | |
ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.024 | |
RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 0.020 | |
SNX9 | sorting nexin 9 | 0.020 | |
PFN1 | profilin 1 | 0.020 | |
PICALM | phosphatidylinositol binding clathrin assembly protein | 0.017 | |
DLG5 | discs, large homolog 5 (Drosophila) | 0.016 | |
CIB1 | calcium and integrin binding 1 (calmyrin) | 0.015 | |
STAU1 | staufen, RNA binding protein, homolog 1 (Drosophila) | 0.014 | |
CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.013 | |
COTL1 | coactosin-like 1 (Dictyostelium) | 0.013 | |
ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | 0.011 |