The network for 'ketone catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

ketone catabolic process

The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)1.000
CYP4F2cytochrome P450, family 4, subfamily F, polypeptide 20.912
SOD1superoxide dismutase 1, soluble0.842
CYP4F12cytochrome P450, family 4, subfamily F, polypeptide 120.680
CYP4F3cytochrome P450, family 4, subfamily F, polypeptide 30.584
RAB35RAB35, member RAS oncogene family0.356
CYP3A43cytochrome P450, family 3, subfamily A, polypeptide 430.173
SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.146
CYP2B6cytochrome P450, family 2, subfamily B, polypeptide 60.138
CCDC78coiled-coil domain containing 780.134
AKR1C4aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)0.111
C1orf123chromosome 1 open reading frame 1230.094
RBBP7retinoblastoma binding protein 70.088
PRDX2peroxiredoxin 20.079
CYP4F11cytochrome P450, family 4, subfamily F, polypeptide 110.076
ABCC2ATP-binding cassette, sub-family C (CFTR/MRP), member 20.075
DIO1deiodinase, iodothyronine, type I0.072
CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 40.061
CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 90.053
BCL11BB-cell CLL/lymphoma 11B (zinc finger protein)0.052
PRDX5peroxiredoxin 50.045
AKR1B10aldo-keto reductase family 1, member B10 (aldose reductase)0.045
PRDX4peroxiredoxin 40.040
EPHX2epoxide hydrolase 2, cytoplasmic0.039
AZGP1alpha-2-glycoprotein 1, zinc-binding0.037
SLC2A2solute carrier family 2 (facilitated glucose transporter), member 20.037
GPTglutamic-pyruvate transaminase (alanine aminotransferase)0.036
PIRpirin (iron-binding nuclear protein)0.035
SULT1B1sulfotransferase family, cytosolic, 1B, member 10.035
CYP3A5cytochrome P450, family 3, subfamily A, polypeptide 50.034
HALhistidine ammonia-lyase0.033
TNFRSF10Atumor necrosis factor receptor superfamily, member 10a0.033
URODuroporphyrinogen decarboxylase0.031
SPP2secreted phosphoprotein 2, 24kDa0.030
CYP2C19cytochrome P450, family 2, subfamily C, polypeptide 190.030
ADH6alcohol dehydrogenase 6 (class V)0.030
KNG1kininogen 10.029
FBXO7F-box protein 70.027
CYP3A7cytochrome P450, family 3, subfamily A, polypeptide 70.026
FASFas (TNF receptor superfamily, member 6)0.026
GSTA3glutathione S-transferase alpha 30.026
FETUBfetuin B0.025
HNF4Ahepatocyte nuclear factor 4, alpha0.025
G6PCglucose-6-phosphatase, catalytic subunit0.024
HSD17B2hydroxysteroid (17-beta) dehydrogenase 20.024
USMG5up-regulated during skeletal muscle growth 5 homolog (mouse)0.024
CYP4B1cytochrome P450, family 4, subfamily B, polypeptide 10.024
FABP1fatty acid binding protein 1, liver0.023
SIN3ASIN3 homolog A, transcription regulator (yeast)0.023
CYP2C18cytochrome P450, family 2, subfamily C, polypeptide 180.022
CES1carboxylesterase 10.022
PRDX6peroxiredoxin 60.022
RDH16retinol dehydrogenase 16 (all-trans)0.022
APOC3apolipoprotein C-III0.022
HDAC1histone deacetylase 10.021
CRPC-reactive protein, pentraxin-related0.021
SULT1E1sulfotransferase family 1E, estrogen-preferring, member 10.020
TFR2transferrin receptor 20.020
AADACarylacetamide deacetylase (esterase)0.019
SPSB3splA/ryanodine receptor domain and SOCS box containing 30.019
C8Bcomplement component 8, beta polypeptide0.019
NQO1NAD(P)H dehydrogenase, quinone 10.019
SULT2A1sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 10.019
AKR7A2aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)0.018
FADDFas (TNFRSF6)-associated via death domain0.018
GSTT1glutathione S-transferase theta 10.018
ALDH1L1aldehyde dehydrogenase 1 family, member L10.018
SEC14L2SEC14-like 2 (S. cerevisiae)0.018
ARG1arginase, liver0.018
CYP2C8cytochrome P450, family 2, subfamily C, polypeptide 80.018
KLKB1kallikrein B, plasma (Fletcher factor) 10.017
F12coagulation factor XII (Hageman factor)0.017
CYP2J2cytochrome P450, family 2, subfamily J, polypeptide 20.016
DAD1defender against cell death 10.016
ACAA1acetyl-CoA acyltransferase 10.016
DEFB1defensin, beta 10.016
FMO4flavin containing monooxygenase 40.016
APOFapolipoprotein F0.016
PIPprolactin-induced protein0.016
BREbrain and reproductive organ-expressed (TNFRSF1A modulator)0.016
CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 10.015
OSGIN1oxidative stress induced growth inhibitor 10.015
ADH1Calcohol dehydrogenase 1C (class I), gamma polypeptide0.015
CRISP3cysteine-rich secretory protein 30.015
PINK1PTEN induced putative kinase 10.015
HGDhomogentisate 1,2-dioxygenase0.015
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.015
PLGplasminogen0.014
CBR1carbonyl reductase 10.014
FRS2fibroblast growth factor receptor substrate 20.014
SLC13A2solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 20.013
C8Gcomplement component 8, gamma polypeptide0.013
PCK1phosphoenolpyruvate carboxykinase 1 (soluble)0.013
ACO1aconitase 1, soluble0.013
C4BPAcomplement component 4 binding protein, alpha0.013
BBOX1butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 10.013
PRODHproline dehydrogenase (oxidase) 10.013
CDAcytidine deaminase0.013
CHST8carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 80.013
MOSC1MOCO sulphurase C-terminal domain containing 10.013
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Apoa1bpapolipoprotein A-I binding protein0.480
Surf1surfeit gene 10.291
1810046J19RikRIKEN cDNA 1810046J19 gene0.232
Mosc2MOCO sulphurase C-terminal domain containing 20.201
Ufc1ubiquitin-fold modifier conjugating enzyme 10.181
Qdprquinoid dihydropteridine reductase0.156
Gsta4glutathione S-transferase, alpha 40.141
Tbcbtubulin folding cofactor B0.137
Nphp1nephronophthisis 1 (juvenile) homolog (human)0.136
0610011F06RikRIKEN cDNA 0610011F06 gene0.131
Mrpl13mitochondrial ribosomal protein L130.122
Ppa2pyrophosphatase (inorganic) 20.120
Sirt3sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae)0.111
Fam173afamily with sequence similarity 173, member A0.109
Eif3ieukaryotic translation initiation factor 3, subunit I0.098
Higd2aHIG1 domain family, member 2A0.095
Taldo1transaldolase 10.092
Lamp1lysosomal-associated membrane protein 10.090
Phpt1phosphohistidine phosphatase 10.079
Fuca1fucosidase, alpha-L- 1, tissue0.069
Sil1endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)0.065
Bcap31B-cell receptor-associated protein 310.063
Prdx1peroxiredoxin 10.062
Hsd17b4hydroxysteroid (17-beta) dehydrogenase 40.060
BC004004cDNA sequence BC0040040.058
Rnh1ribonuclease/angiogenin inhibitor 10.054
Pcbd2pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 20.053
Carkdcarbohydrate kinase domain containing0.051
Cyb5cytochrome b-50.048
Itm2cintegral membrane protein 2C0.048
BC031181cDNA sequence BC0311810.046
Cnpy2canopy 2 homolog (zebrafish)0.046
Bag1BCL2-associated athanogene 10.045
Rnf181ring finger protein 1810.045
Ngrnneugrin, neurite outgrowth associated0.043
Stk39serine/threonine kinase 39, STE20/SPS1 homolog (yeast)0.040
Cltaclathrin, light polypeptide (Lca)0.040
Mrps25mitochondrial ribosomal protein S250.040
Gstk1glutathione S-transferase kappa 10.039
Edf1endothelial differentiation-related factor 10.038
Tmem205transmembrane protein 2050.038
Leprleptin receptor0.038
Romo1reactive oxygen species modulator 10.038
Pebp1phosphatidylethanolamine binding protein 10.038
Chmp2achromatin modifying protein 2A0.037
Ergic3ERGIC and golgi 30.037
Glrx3glutaredoxin 30.035
Slc12a1solute carrier family 12, member 10.034
AI462493expressed sequence AI4624930.034
Arl6ip4ADP-ribosylation factor-like 6 interacting protein 40.034
Bckdhabranched chain ketoacid dehydrogenase E1, alpha polypeptide0.034
Agtr1aangiotensin II receptor, type 1a0.034
Cndp2CNDP dipeptidase 2 (metallopeptidase M20 family)0.032
Mrpl24mitochondrial ribosomal protein L240.032
6720456B07RikRIKEN cDNA 6720456B07 gene0.030
Slc25a4solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 40.030
Tmem223transmembrane protein 2230.030
Cldn10claudin 100.030
Copecoatomer protein complex, subunit epsilon0.030
Gstp1glutathione S-transferase, pi 10.030
Rexo2REX2, RNA exonuclease 2 homolog (S. cerevisiae)0.029
Anapc13anaphase promoting complex subunit 130.028
Hint1histidine triad nucleotide binding protein 10.028
Cpsf3cleavage and polyadenylation specificity factor 30.028
Ftl1ferritin light chain 10.026
Arl3ADP-ribosylation factor-like 30.026
Uroduroporphyrinogen decarboxylase0.026
Prpf19PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)0.025
Cd81CD81 antigen0.025
Gsto1glutathione S-transferase omega 10.025
Ppiapeptidylprolyl isomerase A0.025
Mutedmuted0.025
Ift27intraflagellar transport 27 homolog (Chlamydomonas)0.025
Coq7demethyl-Q 70.024
Pepdpeptidase D0.024
Ei24etoposide induced 2.4 mRNA0.024
Dcxrdicarbonyl L-xylulose reductase0.024
Lcmt1leucine carboxyl methyltransferase 10.024
0610007C21RikRIKEN cDNA 0610007C21 gene0.023
Hsd17b10hydroxysteroid (17-beta) dehydrogenase 100.023
Acaa1bacetyl-Coenzyme A acyltransferase 1B0.023
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.023
Pnpopyridoxine 5'-phosphate oxidase0.023
Dhrs1dehydrogenase/reductase (SDR family) member 10.022
Akr1a4aldo-keto reductase family 1, member A4 (aldehyde reductase)0.022
2810405K02RikRIKEN cDNA 2810405K02 gene0.022
Ccdc107coiled-coil domain containing 1070.022
Psmb3proteasome (prosome, macropain) subunit, beta type 30.022
Slc37a4solute carrier family 37 (glucose-6-phosphate transporter), member 40.022
Lxnlatexin0.022
Atp6v1fATPase, H+ transporting, lysosomal V1 subunit F0.021
Mrps6mitochondrial ribosomal protein S60.021
Idh3gisocitrate dehydrogenase 3 (NAD+), gamma0.021
Trappc3trafficking protein particle complex 30.020
Arpc1aactin related protein 2/3 complex, subunit 1A0.019
Avpi1arginine vasopressin-induced 10.019
Cbr1carbonyl reductase 10.019
Fntafarnesyltransferase, CAAX box, alpha0.019
Cops6COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)0.019
Glod4glyoxalase domain containing 40.019
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism