The network for 'g1 s transition of mitotic cell cycle' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

g1 s transition of mitotic cell cycle

The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.

NameDescriptionProbabilityFunc Analog Organism
CDC28Cdc28p0.930
SIC1Sic1p0.727
CKS1Cks1p0.706
CDC4Cdc4p0.681
HHO1Hho1p0.647
RSC4Rsc4p0.611
MSA1Msa1p0.607
SWI6Swi6p0.594
CLN1Cln1p0.569
SWI5Swi5p0.567
CLB5Clb5p0.562
CDC14Cdc14p0.520
SIT4Sit4p0.509
PPH22Pph22p0.458
RTF1Rtf1p0.453
WHI5Whi5p0.445
SWI4Swi4p0.435
CLN2Cln2p0.434
CDC34Cdc34p0.426
MSA2Msa2p0.390
FKH2Fkh2p0.341
MIG1Mig1p0.333
TIF4632Tif4632p0.286
ADR1Adr1p0.286
HIR2Hir2p0.277
CLN3Cln3p0.274
TAF6Taf6p0.270
RTG3Rtg3p0.264
CLB3Clb3p0.262
PPH21Pph21p0.250
NUP157Nup157p0.246
HST3Hst3p0.241
CDC6Cdc6p0.219
CLB2Clb2p0.218
NRM1Nrm1p0.210
TPD3Tpd3p0.202
CLB6Clb6p0.192
GIN4Gin4p0.190
SKP1Skp1p0.186
YPL014Whypothetical protein0.181
SIP2Sip2p0.181
SWI3Swi3p0.171
MIG2Mig2p0.169
MBP1Mbp1p0.169
CLB1Clb1p0.169
RTS3Rts3p0.168
PPH3Pph3p0.162
PSF1Psf1p0.162
ARP8Arp8p0.161
SPT16Spt16p0.160
TOR1Tor1p0.148
SLD2Sld2p0.147
IES1Ies1p0.143
TOR2Tor2p0.142
DSE3Dse3p0.140
IES3Ies3p0.139
HTB2Htb2p0.133
CKA1Cka1p0.130
LTE1Lte1p0.128
NET1Net1p0.127
FKH1Fkh1p0.121
HIR1Hir1p0.118
MSN4Msn4p0.117
NDD1Ndd1p0.114
SAK1Sak1p0.114
SPC98Spc98p0.114
AFT1Aft1p0.113
MUS81Mus81p0.110
CDC53Cdc53p0.107
GIC1Gic1p0.106
MCM1Mcm1p0.104
MOT1Mot1p0.102
STP4Stp4p0.099
HAL5Hal5p0.099
SPT5Spt5p0.098
PTK2Ptk2p0.098
CRZ1Crz1p0.097
NRG1Nrg1p0.097
KSP1Ksp1p0.096
HXT3Hxt3p0.095
CSR2Csr2p0.092
SPT15Spt15p0.091
KCC4Kcc4p0.091
KIN1Kin1p0.091
SET2Set2p0.090
RSC2Rsc2p0.089
VID24Vid24p0.089
SKS1Sks1p0.088
SAP190Sap190p0.088
RSC8Rsc8p0.087
PSK1Psk1p0.086
MCM3Mcm3p0.086
SFG1Sfg1p0.084
LYS5Lys5p0.084
SEF1Sef1p0.083
PSP2Psp2p0.081
AIM20Aim20p0.077
SWI1Swi1p0.077
YLR455Whypothetical protein0.076
YRR1Yrr1p0.076
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
cul-2Protein CUL-20.040
lig-1Protein LIG-10.035
ced-9Protein CED-90.030
egl-18Protein EGL-180.030
let-60Protein LET-600.027
swsn-7Protein SWSN-70.026
sli-1Protein SLI-10.025
csn-5Protein CSN-50.024
prp-8Protein PRP-80.024
K03H4.2Protein K03H4.20.024
pha-4Protein PHA-40.024
K02A11.3Protein K02A11.30.023
kin-29Protein KIN-290.023
trr-1Protein TRR-10.023
apc-2Protein APC-20.023
CELE_C24H12.5Protein C24H12.50.023
air-1Protein AIR-10.023
R05D3.2Protein R05D3.20.022
Y71H2B.2Protein Y71H2B.20.021
F37C4.5Protein F37C4.50.021
rpl-16Protein RPL-160.021
mix-1Protein MIX-10.021
plc-3Protein PLC-30.020
ZK524.4Protein ZK524.40.020
cyn-15Protein CYN-150.020
sel-12Protein SEL-120.020
R02F11.4Protein R02F11.40.020
zyg-11Protein ZYG-110.020
Y44E3A.6Protein Y44E3A.60.020
atg-18Protein ATG-180.020
ifg-1Protein IFG-10.020
Y17G7B.17Protein Y17G7B.170.019
lin-12Protein LIN-120.019
flt-1Protein FLT-10.019
daf-21Protein DAF-210.019
sig-7Protein SIG-70.019
xpo-1Protein XPO-10.019
F31C3.3Protein F31C3.30.019
fox-1Protein FOX-10.019
cdc-25.1Protein CDC-25.10.019
mcm-7Protein MCM-70.018
mcm-2Protein MCM-20.018
C34F6.9Protein C34F6.90.018
CELE_F25B4.5Protein F25B4.50.018
elc-1Protein ELC-10.018
ran-1Protein RAN-10.018
T22C1.1Protein T22C1.10.018
zim-1Protein ZIM-10.018
npp-8Protein NPP-80.018
bet-1Protein BET-10.018
F59E12.1Protein F59E12.10.018
K10C3.4Protein K10C3.40.018
F39G3.3Protein F39G3.30.018
top-2Protein TOP-20.018
sel-8Protein SEL-80.018
snfc-5Protein SNFC-50.017
hmg-4Protein HMG-40.017
glp-1Protein GLP-10.017
rfc-4Protein RFC-40.017
icp-1Protein ICP-10.017
eef-1GProtein EEF-1G0.017
vab-1Protein VAB-10.017
W08E3.2Protein W08E3.20.017
gon-2Protein GON-20.017
ulp-2Protein ULP-20.017
pisy-1Protein PISY-10.017
F58G11.3Protein F58G11.30.017
dsh-2Protein DSH-20.017
cfim-2Protein CFIM-20.017
pbrm-1Protein PBRM-10.017
cdt-1Protein CDT-10.017
CELE_C50B6.3Protein C50B6.30.017
cpb-1Protein CPB-10.016
hcf-1Protein HCF-10.016
tam-1Protein TAM-10.016
mel-28Protein MEL-280.016
gla-3Protein GLA-30.016
hsp-43Protein HSP-430.016
attf-2Protein ATTF-20.016
F25H5.8Protein F25H5.80.016
rpn-2Protein RPN-20.016
hcp-6Protein HCP-60.016
vps-26Protein VPS-260.016
CELE_W05H9.2Protein W05H9.20.016
K07E3.2Protein K07E3.20.016
nhr-69Protein NHR-690.016
swsn-4Protein SWSN-40.016
T18D3.1Protein T18D3.10.016
F33H2.3Protein F33H2.30.016
panl-2Protein PANL-20.016
trim-9Protein TRIM-90.016
R05D11.9Protein R05D11.90.016
C35C5.3Protein C35C5.30.016
npp-1Protein NPP-10.016
mom-2Protein MOM-20.016
plk-1Protein PLK-10.016
scc-3Protein SCC-30.016
ttm-1Protein TTM-10.016
swsn-3Protein SWSN-30.016
asd-1Protein ASD-10.016
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
itgb1b.2integrin, beta 1b.20.669
ccnd1cyclin D10.597
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.558
tp53tumor protein p530.502
itgb1aintegrin, beta 1a0.499
gli2aGLI-Kruppel family member GLI2a0.496
ptenbphosphatase and tensin homolog B (mutated in multiple advanced cancers 1)0.435
zff9zinc finger protein 90.293
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.259
dnmt7DNA (cytosine-5-)-methyltransferase 70.259
hoxd4ahomeo box D4a0.245
rbb4retinoblastoma binding protein 40.207
igf1rbinsulin-like growth factor 1b receptor0.191
cfl2lcofilin 2, like0.190
ndr1nodal-related 10.189
anxa1bannexin A1b0.186
smad9MAD homolog 9 (Drosophila)0.172
mycamyelocytomatosis oncogene a0.166
nutf2lnuclear transport factor 2, like0.164
arl4abADP-ribosylation factor-like 4ab0.160
orc6origin recognition complex, subunit 60.158
wu:fb76c12wu:fb76c120.158
fabp11afatty acid binding protein 11a0.154
ptger4aprostaglandin E receptor 4 (subtype EP4) a0.154
zgc:110113zgc:1101130.145
klf2aKruppel-like factor 2a0.142
stmn1bstathmin 1b0.141
fancd2Fanconi anemia, complementation group D20.141
olig4oligodendrocyte transcription factor 40.139
gro2groucho 20.136
zgc:165373zgc:1653730.133
dtldenticleless homolog (Drosophila)0.128
LOC100150924DNA polymerase subunit gamma-1-like0.126
tal1T-cell acute lymphocytic leukemia 10.120
ccna2cyclin A20.119
smyhc1slow myosin heavy chain 10.118
ndnl2necdin-like 20.115
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.114
gadd45bagrowth arrest and DNA-damage-inducible, beta a0.111
bocbrother of CDO0.109
ass1argininosuccinate synthetase 10.107
itgb1bintegrin, beta 1b0.105
gata3GATA-binding protein 30.105
nr2f5nuclear receptor subfamily 2, group F, member 50.102
tcf7l1atranscription factor 7-like 1a (T-cell specific, HMG-box)0.100
mcm6MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)0.098
tipintimeless interacting protein0.096
akirin1akirin 10.096
ca15bcarbonic anhydrase XV b0.095
LOC100000687signal peptide, CUB and EGF-like domain-containing protein 3-like0.094
whsc1Wolf-Hirschhorn syndrome candidate 10.092
gro1groucho 10.090
ptgs2aprostaglandin-endoperoxide synthase 2a0.090
LOC566708FL cytokine receptor-like0.089
nrg1neuregulin 10.087
rpa3replication protein A30.087
hsd11b2hydroxysteroid 11-beta dehydrogenase 20.087
LOC100151531zinc finger protein Gfi-1b-like0.086
gsnagelsolin a0.085
tgfb1atransforming growth factor, beta 1a0.084
pld1aphospholipase D1a0.082
mcmbpminichromosome maintenance complex binding protein0.082
stc1lstanniocalcin 1, like0.081
ptger2aprostaglandin E receptor 2a (subtype EP2)0.080
g3bp1GTPase activating protein (SH3 domain) binding protein 10.080
twist1atwist1a0.080
gmnngeminin, DNA replication inhibitor0.080
notch1bnotch homolog 1b0.079
ppargc1alperoxisome proliferator-activated receptor gamma, coactivator 1 alpha like0.079
dag1dystroglycan 10.078
zgc:92061zgc:920610.078
tbpl2TATA box binding protein like 20.078
hspb7heat shock protein family, alpha-crystallin-related, b70.077
gata1aGATA binding protein 1a0.076
si:dkeyp-113d7.7si:dkeyp-113d7.70.076
icn2ictacalcin 20.074
slc2a10solute carrier family 2 (facilitated glucose transporter), member 100.074
nfatc1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 10.074
rnf2ring finger protein 20.073
tshbthyroid stimulating hormone, beta subunit0.073
gadd45aagrowth arrest and DNA-damage-inducible, alpha, a0.073
btg2B-cell translocation gene 20.073
cdt1chromatin licensing and DNA replication factor 10.072
vps26avacuolar protein sorting 26 homolog A (yeast)0.072
gtf2bgeneral transcription factor IIB0.072
zgc:65979zgc:659790.072
mstnamyostatin a0.071
igfbp6ainsulin-like growth factor binding protein 6a0.071
dzip1DAZ interacting protein 10.070
ccnt2acyclin T2a0.070
igfbp3insulin-like growth factor binding protein 30.069
dlcdeltaC0.069
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.069
zgc:110434zgc:1104340.069
aldh1a2aldehyde dehydrogenase 1 family, member A20.068
sox3SRY-box containing gene 30.068
si:ch211-215h6.2si:ch211-215h6.20.068
fabp7afatty acid binding protein 7, brain, a0.067
ube2g2ubiquitin-conjugating enzyme E2G 20.067
fam84afamily with sequence similarity 84, member A0.067
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
RbfRetinoblastoma-family protein0.929
Ras85DRas oncogene at 85D0.746
dapdacapo0.674
Akt1CG4006 gene product from transcript CG4006-RA0.597
shnschnurri0.433
MadMothers against dpp0.369
giggigas0.349
PtenCG5671 gene product from transcript CG5671-RB0.307
Stat92ESignal-transducer and activator of transcription protein at 92E0.295
Pk61CProtein kinase 61C0.263
Vap-33-1CG5014 gene product from transcript CG5014-RB0.247
phlpole hole0.231
cdc2cCG10498 gene product from transcript CG10498-RC0.218
DpDP transcription factor0.210
Pi3K92ECG4141 gene product from transcript CG4141-RB0.187
EcREcdysone receptor0.187
tkvthickveins0.178
osaCG7467 gene product from transcript CG7467-RD0.167
ykiyorkie0.160
hephhephaestus0.157
Myd88CG2078 gene product from transcript CG2078-RA0.155
CycACyclin A0.124
cicubitus interruptus0.119
Cdk4Cyclin-dependent kinase 40.115
rapretina aberrant in pattern0.106
CSN8COP9 complex homolog subunit 80.093
Pabp2CG2163 gene product from transcript CG2163-RA0.089
RASSF8CG5053 gene product from transcript CG5053-RA0.085
Rab11Rab-protein 110.084
hephemipterous0.083
CycBCyclin B0.080
dmdiminutive0.080
MerMerlin0.079
belbelle0.075
kaykayak0.075
jubAjuba LIM protein0.073
spensplit ends0.069
Tao-1CG14217 gene product from transcript CG14217-RF0.065
MED6Mediator complex subunit 60.062
l(1)dd4lethal (1) discs degenerate 40.061
p53CG33336 gene product from transcript CG33336-RB0.060
RecQ4CG7487 gene product from transcript CG7487-RA0.059
cazcabeza0.056
SmrSmrter0.056
cnkconnector enhancer of ksr0.052
Tsc1CG6147 gene product from transcript CG6147-RA0.052
mip120Myb-interacting protein 1200.051
myoglianinCG1838 gene product from transcript CG1838-RD0.050
HmgDHigh mobility group protein D0.050
MedMedea0.049
Psf2CG18013 gene product from transcript CG18013-RA0.049
Map60Microtubule-associated protein 600.049
CG9339CG9339 gene product from transcript CG9339-RG0.049
gekgenghis khan0.048
CycDCyclin D0.048
brmbrahma0.047
MED17Mediator complex subunit 170.047
Rm62CG10279 gene product from transcript CG10279-RD0.045
Mes2CG11100 gene product from transcript CG11100-RB0.044
CycGCyclin G0.043
imdimmune deficiency0.043
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.043
Atf6CG3136 gene product from transcript CG3136-RA0.042
SAKSak kinase0.042
sdscalloped0.042
wdbwiderborst0.041
CycECyclin E0.041
piepineapple eye0.041
embembargoed0.040
skdskuld0.040
ktokohtalo0.040
gbbglass bottom boat0.039
SfmbtScm-related gene containing four mbt domains0.039
Rac1CG2248 gene product from transcript CG2248-RA0.039
Fs(2)KetFemale sterile (2) Ketel0.039
panpangolin0.039
fdlfused lobes0.039
CG4400CG4400 gene product from transcript CG4400-RA0.038
asf1anti-silencing factor 10.038
CG9772CG9772 gene product from transcript CG9772-RB0.038
hpohippo0.036
growlCG14648 gene product from transcript CG14648-RA0.035
PcPolycomb0.035
CblCG7037 gene product from transcript CG7037-RB0.034
Mcm3Minichromosome maintenance 30.034
bratbrain tumor0.034
CtBPC-terminal Binding Protein0.034
TorTarget of rapamycin0.034
simjsimjang0.033
cdc2CG5363 gene product from transcript CG5363-RA0.033
eIF4AIIICG7483 gene product from transcript CG7483-RA0.033
MED26Mediator complex subunit 260.033
picpiccolo0.033
RnrLRibonucleoside diphosphate reductase large subunit0.032
emcextra macrochaetae0.032
e(y)3enhancer of yellow 30.032
SnooSno oncogene0.031
cdmcadmus0.031
agoarchipelago0.031
mad2CG17498 gene product from transcript CG17498-RA0.031
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CDK2cyclin-dependent kinase 21.000
MDM2Mdm2 p53 binding protein homolog (mouse)1.000
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.999
RB1retinoblastoma 10.999
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.981
RBL2retinoblastoma-like 2 (p130)0.975
E2F1E2F transcription factor 10.967
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)0.963
NOTCH1notch 10.960
CASP3caspase 3, apoptosis-related cysteine peptidase0.936
CDC6cell division cycle 6 homolog (S. cerevisiae)0.919
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.909
FGFR2fibroblast growth factor receptor 20.891
YY1YY1 transcription factor0.886
CHEK2CHK2 checkpoint homolog (S. pombe)0.886
CDK6cyclin-dependent kinase 60.867
JAG1jagged 10.852
SKP1S-phase kinase-associated protein 10.846
RBL1retinoblastoma-like 1 (p107)0.822
CCND1cyclin D10.804
SKP2S-phase kinase-associated protein 2 (p45)0.768
CASP2caspase 2, apoptosis-related cysteine peptidase0.699
CDC5LCDC5 cell division cycle 5-like (S. pombe)0.684
EGFRepidermal growth factor receptor0.654
CCNA2cyclin A20.651
PPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma0.642
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.590
SMAD7SMAD family member 70.573
CUL1cullin 10.552
EIF4Eeukaryotic translation initiation factor 4E0.534
INADLInaD-like (Drosophila)0.515
NCOA1nuclear receptor coactivator 10.512
CDK4cyclin-dependent kinase 40.508
TFDP2transcription factor Dp-2 (E2F dimerization partner 2)0.482
CREBBPCREB binding protein0.479
CCND3cyclin D30.470
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.454
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.453
TFDP1transcription factor Dp-10.448
FBXW11F-box and WD repeat domain containing 110.436
CDK1cyclin-dependent kinase 10.415
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.398
E2F7E2F transcription factor 70.390
E2F8E2F transcription factor 80.389
CKS1BCDC28 protein kinase regulatory subunit 1B0.386
BCL2B-cell CLL/lymphoma 20.374
MTORmechanistic target of rapamycin (serine/threonine kinase)0.368
NXF1nuclear RNA export factor 10.363
EP300E1A binding protein p3000.359
BTRCbeta-transducin repeat containing0.359
GSK3Bglycogen synthase kinase 3 beta0.350
E2F4E2F transcription factor 4, p107/p130-binding0.349
FASLGFas ligand (TNF superfamily, member 6)0.348
FASFas (TNF receptor superfamily, member 6)0.344
IER3immediate early response 30.342
XIAPX-linked inhibitor of apoptosis0.340
CASP8caspase 8, apoptosis-related cysteine peptidase0.333
FGFR1fibroblast growth factor receptor 10.333
TP53tumor protein p530.332
UHRF2ubiquitin-like with PHD and ring finger domains 20.331
ABI2abl-interactor 20.331
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.331
CCNE1cyclin E10.322
FKBP1AFK506 binding protein 1A, 12kDa0.309
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.305
MCM2minichromosome maintenance complex component 20.305
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.303
SETD7SET domain containing (lysine methyltransferase) 70.288
BCORBCL6 corepressor0.282
APAF1apoptotic peptidase activating factor 10.270
PPP1CCprotein phosphatase 1, catalytic subunit, gamma isozyme0.259
HNRNPUL1heterogeneous nuclear ribonucleoprotein U-like 10.247
HEXIM1hexamethylene bis-acetamide inducible 10.245
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha0.243
EIF4EBP3eukaryotic translation initiation factor 4E binding protein 30.243
LIN9lin-9 homolog (C. elegans)0.241
STK38Lserine/threonine kinase 38 like0.234
DDB1damage-specific DNA binding protein 1, 127kDa0.234
PRNPprion protein0.232
CDT1chromatin licensing and DNA replication factor 10.226
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.225
POU3F2POU class 3 homeobox 20.222
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.217
AHRaryl hydrocarbon receptor0.211
CDC27cell division cycle 27 homolog (S. cerevisiae)0.210
CDK9cyclin-dependent kinase 90.203
CRADDCASP2 and RIPK1 domain containing adaptor with death domain0.199
RYBPRING1 and YY1 binding protein0.197
CNOT8CCR4-NOT transcription complex, subunit 80.192
RUNX1runt-related transcription factor 10.190
AKT1v-akt murine thymoma viral oncogene homolog 10.186
ARID1BAT rich interactive domain 1B (SWI1-like)0.184
NEDD4neural precursor cell expressed, developmentally down-regulated 40.183
HBP1HMG-box transcription factor 10.182
PRKCZprotein kinase C, zeta0.177
MCM7minichromosome maintenance complex component 70.176
FOXM1forkhead box M10.175
KEAP1kelch-like ECH-associated protein 10.175
PPP2R1Bprotein phosphatase 2, regulatory subunit A, beta0.169
BMP2bone morphogenetic protein 20.166
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 531.000
Rb1retinoblastoma 10.998
E2f1E2F transcription factor 10.992
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.983
Cdkn1bcyclin-dependent kinase inhibitor 1B0.976
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.922
Mdm2transformed mouse 3T3 cell double minute 20.882
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.862
Nf1neurofibromatosis 10.855
Id1inhibitor of DNA binding 10.843
Ptpn11protein tyrosine phosphatase, non-receptor type 110.834
BaxBCL2-associated X protein0.823
Notch1Notch gene homolog 1 (Drosophila)0.771
Mdm4transformed mouse 3T3 cell double minute 40.742
Arid1bAT rich interactive domain 1B (SWI-like)0.740
Pcnaproliferating cell nuclear antigen0.649
Cdk4cyclin-dependent kinase 40.637
Jarid2jumonji, AT rich interactive domain 20.626
Ptenphosphatase and tensin homolog0.610
Bcl2B-cell leukemia/lymphoma 20.596
Tgfb2transforming growth factor, beta 20.596
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.586
Ccne1cyclin E10.555
SkilSKI-like0.553
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.536
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.533
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.516
Tcf3transcription factor 30.513
Suz12suppressor of zeste 12 homolog (Drosophila)0.482
Kitkit oncogene0.475
Itgb1integrin beta 1 (fibronectin receptor beta)0.461
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.439
Gli3GLI-Kruppel family member GLI30.420
Apcadenomatosis polyposis coli0.403
Meox2mesenchyme homeobox 20.398
Cdk2cyclin-dependent kinase 20.374
Psen1presenilin 10.369
Trp63transformation related protein 630.369
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.358
Nfatc3nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 30.354
Ccna2cyclin A20.345
BrafBraf transforming gene0.344
Cdkn2acyclin-dependent kinase inhibitor 2A0.340
Ighimmunoglobulin heavy chain complex0.336
Fgfr1fibroblast growth factor receptor 10.332
Cd80CD80 antigen0.324
Cdkn2ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)0.321
Socs1suppressor of cytokine signaling 10.312
Plk1polo-like kinase 1 (Drosophila)0.298
Cdk1cyclin-dependent kinase 10.297
Ctnnb1catenin (cadherin associated protein), beta 10.295
Ptch1patched homolog 10.290
Ccnd2cyclin D20.287
Rararetinoic acid receptor, alpha0.284
Ube2cubiquitin-conjugating enzyme E2C0.282
Brca1breast cancer 10.260
Map3k7mitogen-activated protein kinase kinase kinase 70.259
Aurkaaurora kinase A0.249
Smad5MAD homolog 5 (Drosophila)0.249
Retret proto-oncogene0.243
Hes1hairy and enhancer of split 1 (Drosophila)0.241
Msh2mutS homolog 2 (E. coli)0.236
Cdk6cyclin-dependent kinase 60.235
Bmpr1abone morphogenetic protein receptor, type 1A0.232
Birc5baculoviral IAP repeat-containing 50.229
Smarca2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.218
Id3inhibitor of DNA binding 30.212
Bmp4bone morphogenetic protein 40.210
Brca2breast cancer 20.204
Tcf4transcription factor 40.202
Cdkn2dcyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)0.198
Nbnnibrin0.198
Tcf7l1transcription factor 7-like 1 (T-cell specific, HMG box)0.197
Sox9SRY-box containing gene 90.192
Klf3Kruppel-like factor 3 (basic)0.190
Arid1aAT rich interactive domain 1A (SWI-like)0.187
Ccnd1cyclin D10.179
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.178
Anxa5annexin A50.178
Ccnfcyclin F0.171
Serpinb6aserine (or cysteine) peptidase inhibitor, clade B, member 6a0.169
Gtse1G two S phase expressed protein 10.161
DaxxFas death domain-associated protein0.160
S100a11S100 calcium binding protein A11 (calgizzarin)0.145
Mybl2myeloblastosis oncogene-like 20.145
Smarcd1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.144
Vhlvon Hippel-Lindau tumor suppressor0.144
Nfe2l2nuclear factor, erythroid derived 2, like 20.143
Sox4SRY-box containing gene 40.140
Ccnb2cyclin B20.137
CblCasitas B-lineage lymphoma0.135
Itga3integrin alpha 30.134
Pds5bPDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)0.133
Smad1MAD homolog 1 (Drosophila)0.133
Rpgrip1lRpgrip1-like0.131
Cdt1chromatin licensing and DNA replication factor 10.130
Thbs1thrombospondin 10.127
Mtormechanistic target of rapamycin (serine/threonine kinase)0.126
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.124
Lgals3lectin, galactose binding, soluble 30.124
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Top2atopoisomerase (DNA) II alpha0.546
Ccnd1cyclin D10.085
Rrm2ribonucleotide reductase M20.084
Cdk4cyclin-dependent kinase 40.070
Cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.059
Cntn3contactin 3 (plasmacytoma associated)0.059
Tubb5tubulin, beta 50.038
Cct4chaperonin containing Tcp1, subunit 4 (delta)0.037
Cdk2cyclin dependent kinase 20.034
Usf2upstream transcription factor 2, c-fos interacting0.031
Mki67antigen identified by monoclonal antibody Ki-670.030
Casp7caspase 70.029
Kif2ckinesin family member 2C0.028
Hmmrhyaluronan mediated motility receptor (RHAMM)0.028
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.027
Tmpothymopoietin0.027
Melkmaternal embryonic leucine zipper kinase0.026
Smad2SMAD family member 20.026
Mobkl1bMOB1, Mps One Binder kinase activator-like 1B (yeast)0.025
Dnah2dynein, axonemal, heavy chain 20.024
Oprm1opioid receptor, mu 10.024
Casp2caspase 20.024
Lmnb1lamin B10.023
Prkceprotein kinase C, epsilon0.023
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.022
Cdkn3cyclin-dependent kinase inhibitor 30.021
Spc25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.021
Sept11septin 110.021
Pttg1pituitary tumor-transforming 10.021
Tcf4transcription factor 40.020
Apba3amyloid beta (A4) precursor protein-binding, family A, member 30.020
Tcfe2atranscription factor E2a0.020
Nfixnuclear factor I/X (CCAAT-binding transcription factor)0.019
Ccnd3cyclin D30.019
Xpo1exportin 1, CRM1 homolog (yeast)0.018
Cdk1cyclin-dependent kinase 10.018
Capza2capping protein (actin filament) muscle Z-line, alpha 20.018
Kifc1kinesin family member C10.018
Mapk3mitogen activated protein kinase 30.018
Fgfr1Fibroblast growth factor receptor 10.018
Csdacold shock domain protein A0.018
Supt16hsuppressor of Ty 16 homolog (S. cerevisiae)0.017
Cbfbcore-binding factor, beta subunit0.017
Cyp2d4cytochrome P450, family 2, subfamily d, polypeptide 40.017
Rln1relaxin 10.017
Nup88nucleoporin 880.017
Caprin1cell cycle associated protein 10.017
Eif1ayeukaryotic translation initiation factor 1A, Y-linked0.017
Zfand6zinc finger, AN1-type domain 60.016
Mcm6minichromosome maintenance complex component 60.016
Traf4af1TRAF4 associated factor 10.016
Olr837olfactory receptor 8370.015
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.015
Ube2cubiquitin-conjugating enzyme E2C0.015
Ccnb1cyclin B10.015
Hckhemopoietic cell kinase0.014
Pcmtd2protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 20.014
Nusap1nucleolar and spindle associated protein 10.014
Tnks2tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 20.014
Rykreceptor-like tyrosine kinase0.014
Aspmasp (abnormal spindle) homolog, microcephaly associated (Drosophila)0.014
Hnrpdheterogeneous nuclear ribonucleoprotein D0.013
CnbpCCHC-type zinc finger, nucleic acid binding protein0.013
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.013
Kif22kinesin family member 220.013
Mbtps1membrane-bound transcription factor peptidase, site 10.013
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.012
Hist1h1ahistone cluster 1, H1a0.012
Hnrnpa3heterogeneous nuclear ribonucleoprotein A30.012
Racgap1Rac GTPase-activating protein 10.012
Parp1poly (ADP-ribose) polymerase 10.011
Ctnna1catenin (cadherin associated protein), alpha 10.011
Cdca3cell division cycle associated 30.011
Fgf14fibroblast growth factor 140.011
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.011
Iqgap1IQ motif containing GTPase activating protein 10.011
Rgs19regulator of G-protein signaling 190.011
Camkk2calcium/calmodulin-dependent protein kinase kinase 2, beta0.011
Svs4seminal vesicle secretory protein 40.011
Map4k4mitogen-activated protein kinase kinase kinase kinase 40.011
Prc1protein regulator of cytokinesis 10.011
Igf2rinsulin-like growth factor 2 receptor0.011
Haao3-hydroxyanthranilate 3,4-dioxygenase0.010
Tap1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)0.010
Myh9myosin, heavy chain 9, non-muscle0.010