The network for 'regulation of striated muscle tissue development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of striated muscle tissue development

Any process that modulates the frequency, rate or extent of striated muscle development.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
bmp2bbone morphogenetic protein 2b0.396
bmp4bone morphogenetic protein 40.248
fzd7bfrizzled homolog 7b0.189
tbx20T-box 200.157
kdrlkinase insert domain receptor like0.129
fgfr1afibroblast growth factor receptor 1a0.126
wnt5bwingless-type MMTV integration site family, member 5b0.114
gli1GLI-Kruppel family member 10.091
wnt11rwingless-type MMTV integration site family, member 11, related0.090
twist3twist30.090
myod1myogenic differentiation 10.080
gli2aGLI-Kruppel family member GLI2a0.071
pcdh8protocadherin 80.068
fstl1bfollistatin-like 1b0.065
fgf10afibroblast growth factor 10a0.060
ptch2patched 20.059
acvr1bactivin A receptor, type IB0.057
dkk1bdickkopf 1b0.056
efnb2aephrin B2a0.051
pcdh18bprotocadherin 18b0.051
sox9bSRY-box containing gene 9b0.051
wnt4awingless-type MMTV integration site family, member 4a0.049
igfbp3insulin-like growth factor binding protein 30.048
cdh2cadherin 2, neuronal0.046
fgf24fibroblast growth factor 240.044
bocbrother of CDO0.044
sox9aSRY-box containing gene 9a0.044
epb4.1l4erythrocyte protein band 4.1-like 40.043
sox17SRY-box containing gene 170.041
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.040
smad1MAD homolog 1 (Drosophila)0.039
gngt2bguanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b0.038
hand2heart and neural crest derivatives expressed transcript 20.038
gbx2gastrulation brain homeo box 20.038
id1inhibitor of DNA binding 10.038
osr1odd-skipped related 1 (Drosophila)0.038
twist1btwist1b0.037
nrg2aneuregulin 2a0.037
tpm4tropomyosin 40.035
lama4laminin, alpha 40.034
fabp11afatty acid binding protein 11a0.034
igf1insulin-like growth factor 10.032
tnfrsfatumor necrosis factor receptor superfamily, member a0.031
fgf17fibroblast growth factor 170.031
klf4aKruppel-like transcription factor 4a0.031
tbx1T-box 10.030
wtipWilms tumor 1 interacting protein0.029
arnt2aryl hydrocarbon receptor nuclear translocator 20.029
sgcdsarcoglycan, delta (dystrophin-associated glycoprotein)0.029
crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.028
mmp2matrix metalloproteinase 20.028
notch1bnotch homolog 1b0.028
wnt3wingless-type MMTV integration site family, member 30.027
map2k4amitogen-activated protein kinase kinase 4a0.027
hoxd13ahomeo box D13a0.026
mstnbmyostatin b0.026
hoxd11ahomeo box D11a0.025
myf5myogenic factor 50.025
ephb4beph receptor B4b0.025
hoxa11bhomeo box A11b0.025
pld1aphospholipase D1a0.024
chdchordin0.024
tfe3atranscription factor binding to IGHM enhancer 3a0.023
tbx2bT-box 2b0.023
sulf1sulfatase 10.023
wnt3awingless-type MMTV integration site family, member 3A0.023
nog2noggin 20.023
wnt10awingless-type MMTV integration site family, member 10a0.023
tbx18T-box 180.022
ier2immediate early response 20.022
lmnalamin A0.022
has2hyaluronan synthase 20.022
bhlhe40basic helix-loop-helix family, member e400.021
fgf3fibroblast growth factor 30.021
smosmoothened homolog (Drosophila)0.021
stmstarmaker0.020
ctgfconnective tissue growth factor0.020
mef2dmyocyte enhancer factor 2d0.020
lft1lefty10.019
wnt1wingless-type MMTV integration site family, member 10.019
tp73tumor protein p730.019
wt1bwilms tumor 1b0.018
hspb7heat shock protein family, alpha-crystallin-related, b70.017
igf1rbinsulin-like growth factor 1b receptor0.017
cry1acryptochrome 1a0.017
wnt8bwingless-type MMTV integration site family, member 8b0.017
gpr126G protein-coupled receptor 1260.017
syncriplsynaptotagmin binding, cytoplasmic RNA interacting protein, like0.017
ryr2bryanodine receptor 2b (cardiac)0.017
gdnfglial cell derived neurotrophic factor0.017
hs3st3b1aheparan sulfate (glucosamine) 3-O-sulfotransferase 3B1a0.016
rxrbbretinoid x receptor, beta b0.016
mmp14amatrix metalloproteinase 14a (membrane-inserted)0.016
ncam1aneural cell adhesion molecule 1a0.016
tgfb3transforming growth factor, beta 30.016
og9xOG9 homeobox gene0.016
cxcr4achemokine (C-X-C motif) receptor 4a0.016
dag1dystroglycan 10.015
pdlim7PDZ and LIM domain 70.015
wnt2bbwingless-type MMTV integration site family, member 2Bb0.015
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
snssticks and stones0.996
EgfrEpidermal growth factor receptor0.981
cicubitus interruptus0.927
wgwingless0.805
panpangolin0.712
NNotch0.696
edechinoid0.445
Akt1CG4006 gene product from transcript CG4006-RA0.420
slouslouch0.416
EcREcdysone receptor0.371
InRInsulin-like receptor0.252
Vrp1Verprolin 10.242
pnrpannier0.162
tintinman0.162
acachaete0.141
dcodiscs overgrown0.137
PoxnPox neuro0.132
kirrekin of irre0.126
amosabsent MD neurons and olfactory sensilla0.109
rolsrolling pebbles0.104
atoatonal0.099
slmbsupernumerary limbs0.098
Fas2Fasciclin 20.093
MadMothers against dpp0.081
ptcpatched0.078
UbxUltrabithorax0.078
lmdlame duck0.074
CG9007CG9007 gene product from transcript CG9007-RA0.072
sosine oculis0.068
vgvestigial0.061
dsdachsous0.054
Ras85DRas oncogene at 85D0.053
Mob2CG11711 gene product from transcript CG11711-RC0.052
naunautilus0.051
rstroughest0.049
org-1optomotor-blind-related-gene-10.046
dppdecapentaplegic0.043
E(spl)Enhancer of split0.043
CG42574CG42574 gene product from transcript CG42574-RE0.042
captcapulet0.039
lbeladybird early0.038
bnlbranchless0.037
CG12558CG12558 gene product from transcript CG12558-RA0.035
wbwing blister0.033
twitwist0.031
armarmadillo0.031
RhoGAP100FCG1976 gene product from transcript CG1976-RB0.031
GripGlutamate receptor binding protein0.030
bynbrachyenteron0.029
sdscalloped0.029
AntpAntennapedia0.027
senssenseless0.026
araaraucan0.026
Atx2Ataxin-20.025
perperiod0.024
stumpsCG31317 gene product from transcript CG31317-RC0.023
rnrotund0.023
bibifid0.021
singsingles bar0.021
RicRas which interacts with Calmodulin0.020
zfh1Zn finger homeodomain 10.020
CG14061CG14061 gene product from transcript CG14061-RA0.020
Pde8Phosphodiesterase 80.020
MoeMoesin0.020
LanB1CG7123 gene product from transcript CG7123-RA0.020
norpAno receptor potential A0.019
hephemipterous0.018
scwscrew0.018
CG13627CG13627 gene product from transcript CG13627-RA0.018
zfh2Zn finger homeodomain 20.017
binbiniou0.017
Tsc1CG6147 gene product from transcript CG6147-RA0.017
nabCG33545 gene product from transcript CG33545-RC0.017
ShawShaker cognate w0.016
CG17658CG17658 gene product from transcript CG17658-RA0.016
prcpericardin0.015
pbproboscipedia0.015
rhorhomboid0.015
LrtLeucine-rich tendon-specific protein0.014
trxtrithorax0.014
lunaCG33473 gene product from transcript CG33473-RB0.014
wtswarts0.013
CadNCadherin-N0.013
HimHoles in muscle0.012
ClkClock0.012
Cpr97EbCuticular protein 97Eb0.012
CG4612CG4612 gene product from transcript CG4612-RA0.012
CG11592CG11592 gene product from transcript CG11592-RA0.012
Orct2Organic cation transporter 20.012
dacdachshund0.011
pfkpiefke0.010
foxoforkhead box, sub-group O0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
FGFR2fibroblast growth factor receptor 20.999
SRFserum response factor (c-fos serum response element-binding transcription factor)0.999
FGF1fibroblast growth factor 1 (acidic)0.993
JAG1jagged 10.992
NOTCH1notch 10.979
ESR1estrogen receptor 10.942
FSTL1follistatin-like 10.908
TBX5T-box 50.902
EP300E1A binding protein p3000.890
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.886
HDAC4histone deacetylase 40.801
JUNjun proto-oncogene0.786
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.705
FGF10fibroblast growth factor 100.644
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.519
MEF2Cmyocyte enhancer factor 2C0.519
NCOR2nuclear receptor corepressor 20.459
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.418
MYH7Bmyosin, heavy chain 7B, cardiac muscle, beta0.416
NCOA3nuclear receptor coactivator 30.385
LRP6low density lipoprotein receptor-related protein 60.368
BMPR1Abone morphogenetic protein receptor, type IA0.349
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.343
ENGendoglin0.336
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.330
MYOD1myogenic differentiation 10.314
TTNtitin0.272
RB1retinoblastoma 10.269
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.254
SETD8SET domain containing (lysine methyltransferase) 80.248
ARandrogen receptor0.232
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.213
TGFB3transforming growth factor, beta 30.196
MEF2Amyocyte enhancer factor 2A0.194
CREBBPCREB binding protein0.184
CNOT8CCR4-NOT transcription complex, subunit 80.183
CDK2cyclin-dependent kinase 20.180
IGF2insulin-like growth factor 2 (somatomedin A)0.167
HDAC6histone deacetylase 60.155
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.149
NOTCH3notch 30.143
INO80BINO80 complex subunit B0.138
AXIN1axin 10.135
PLCG1phospholipase C, gamma 10.133
H3F3CH3 histone, family 3C0.129
TNKS2tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 20.128
C5orf41chromosome 5 open reading frame 410.128
FZD1frizzled homolog 1 (Drosophila)0.119
TCF4transcription factor 40.119
ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix protein0.117
SIRT1sirtuin 10.116
PTPN14protein tyrosine phosphatase, non-receptor type 140.107
SMAD7SMAD family member 70.105
CEBPGCCAAT/enhancer binding protein (C/EBP), gamma0.105
CDK1cyclin-dependent kinase 10.097
DDX5DEAD (Asp-Glu-Ala-Asp) box polypeptide 50.093
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.091
HDAC9histone deacetylase 90.088
HIC1hypermethylated in cancer 10.087
FGF7fibroblast growth factor 70.084
DLL1delta-like 1 (Drosophila)0.083
NEDD4neural precursor cell expressed, developmentally down-regulated 40.081
GATA4GATA binding protein 40.080
JAG2jagged 20.079
BCL2L1BCL2-like 10.075
STK3serine/threonine kinase 30.075
CABLES1Cdk5 and Abl enzyme substrate 10.073
SATB2SATB homeobox 20.073
KAT2BK(lysine) acetyltransferase 2B0.070
EPAS1endothelial PAS domain protein 10.070
NCK2NCK adaptor protein 20.069
DDR2discoidin domain receptor tyrosine kinase 20.069
DDX17DEAD (Asp-Glu-Ala-Asp) box polypeptide 170.069
FBLN1fibulin 10.064
BTF3basic transcription factor 30.064
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.061
CDC14BCDC14 cell division cycle 14 homolog B (S. cerevisiae)0.061
MAML1mastermind-like 1 (Drosophila)0.059
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.058
DKK1dickkopf homolog 1 (Xenopus laevis)0.058
WWOXWW domain containing oxidoreductase0.058
BCL6B-cell CLL/lymphoma 60.058
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.057
FZR1fizzy/cell division cycle 20 related 1 (Drosophila)0.055
TP53BP2tumor protein p53 binding protein, 20.054
CLOCKclock homolog (mouse)0.054
HDAC1histone deacetylase 10.052
CXCL11chemokine (C-X-C motif) ligand 110.050
FGF8fibroblast growth factor 8 (androgen-induced)0.050
ZHX1zinc fingers and homeoboxes 10.047
DCNdecorin0.047
DBPD site of albumin promoter (albumin D-box) binding protein0.047
ARRDC3arrestin domain containing 30.046
APPamyloid beta (A4) precursor protein0.044
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.044
EGLN1egl nine homolog 1 (C. elegans)0.043
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.043
FGF3fibroblast growth factor 30.042
MKL1megakaryoblastic leukemia (translocation) 10.042
IRS1insulin receptor substrate 10.042
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cd9CD9 molecule0.105
Muskmuscle, skeletal, receptor tyrosine kinase0.071
S100a9S100 calcium binding protein A90.063
S100a8S100 calcium binding protein A80.060
Sc4molsterol-C4-methyl oxidase-like0.058
Fgfr2fibroblast growth factor receptor 20.052
Anxa2annexin A20.049
S100a6S100 calcium binding protein A60.049
Cav1caveolin 1, caveolae protein0.048
Cdkn3cyclin-dependent kinase inhibitor 30.045
Lgals1lectin, galactoside-binding, soluble, 10.044
Plp2proteolipid protein 2 (colonic epithelium-enriched)0.042
Tgfbr2transforming growth factor, beta receptor II0.041
Prrx1paired related homeobox 10.041
S100a10S100 calcium binding protein A100.037
LOC100362824caveolin 2-like0.035
Ube2cubiquitin-conjugating enzyme E2C0.035
Adam10ADAM metallopeptidase domain 100.031
RGD1564664similar to LOC387763 protein0.031
Camkk2calcium/calmodulin-dependent protein kinase kinase 2, beta0.030
Phkg1phosphorylase kinase, gamma 10.029
Syt8synaptotagmin VIII0.029
Anxa1annexin A10.029
Acracrosin0.028
LOC689399hypothetical protein LOC6893990.027
Smad7SMAD family member 70.027
Nek9NIMA (never in mitosis gene a)- related kinase 90.026
Chrna1cholinergic receptor, nicotinic, alpha 1 (muscle)0.026
Gja3gap junction protein, alpha 30.025
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.025
Nos3nitric oxide synthase 3, endothelial cell0.025
Anxa5annexin A50.025
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.024
Vimvimentin0.024
Dmddystrophin0.024
Grm5glutamate receptor, metabotropic 50.022
Jak1Janus kinase 10.022
Cripcysteine-rich intestinal protein0.022
Ccl4chemokine (C-C motif) ligand 40.021
Pttg1pituitary tumor-transforming 10.020
Cks2CDC28 protein kinase regulatory subunit 20.020
Racgap1Rac GTPase-activating protein 10.020
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.020
Ccl2chemokine (C-C motif) ligand 20.020
Atp6v1fATPase, H transporting, lysosomal V1 subunit F0.019
Myo9amyosin IXA0.019
Crybb2crystallin, beta B20.018
RGD1309036hypothetical LOC2928740.018
Cdk1cyclin-dependent kinase 10.018
Tcfe2atranscription factor E2a0.018
Id1inhibitor of DNA binding 10.018
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.018
Serpine2serine (or cysteine) peptidase inhibitor, clade E, member 20.017
Mpp2membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)0.017
Prkcaprotein kinase C, alpha0.017
Prlprolactin0.017
Hmgb2high mobility group box 20.016
Cyp51cytochrome P450, family 510.016
Mmp9matrix metallopeptidase 90.016
Creb1cAMP responsive element binding protein 10.016
Metmet proto-oncogene0.016
Ncanneurocan0.016
Chrnb3cholinergic receptor, nicotinic, beta 30.016
Tspotranslocator protein0.015
Pkiaprotein kinase (cAMP-dependent, catalytic) inhibitor alpha0.015
Adrb1adrenergic, beta-1-, receptor0.015
Stx2syntaxin 20.015
Prl8a2prolactin family 8, subfamily a, member 20.015
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.015
Il10rainterleukin 10 receptor, alpha0.015
Tnni1troponin I type 1 (skeletal, slow)0.015
Klks3kallikrein, submaxillary gland S30.014
Akt2v-akt murine thymoma viral oncogene homolog 20.014
Notch2Notch homolog 2 (Drosophila)0.014
Gpr176G protein-coupled receptor 1760.014
Hrh1histamine receptor H 10.014
Top2atopoisomerase (DNA) II alpha0.014
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.014
Pou6f1POU class 6 homeobox 10.014
LOC100362331rCG59612-like0.014
Reg3aregenerating islet-derived 3 alpha0.014
Tpm4tropomyosin 40.014
Strnstriatin, calmodulin binding protein0.014
Irs1insulin receptor substrate 10.013
Cav2caveolin 20.013
Il2rainterleukin 2 receptor, alpha0.013
Dbhdopamine beta-hydroxylase (dopamine beta-monooxygenase)0.013
Traf4af1TRAF4 associated factor 10.013
Col12a1collagen, type XII, alpha 10.013
Opn4opsin 40.013
Spt1salivary protein 10.013
Foxi2forkhead box I20.013
Mfrpmembrane frizzled-related protein0.013
Hdgfl1hepatoma derived growth factor-like 10.013
MosMoloney sarcoma oncogene0.012
Fgf14fibroblast growth factor 140.012
Homer3homer homolog 3 (Drosophila)0.012
Nkx2-1NK2 homeobox 10.012
LOC688549hypothetical protein LOC6885490.012
Tax1bp3Tax1 (human T-cell leukemia virus type I) binding protein 30.012