The network for 'dna topological change' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

dna topological change

The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.

NameDescriptionProbabilityFunc Analog Organism
RFA1Rfa1p0.677
RAD53Rad53p0.184
RAD51Rad51p0.112
MEC1Mec1p0.083
DNA2Dna2p0.076
SRS2Srs2p0.074
RMI1Rmi1p0.065
YDL156Whypothetical protein0.057
TOP3Top3p0.055
RAD55Rad55p0.027
HHO1Hho1p0.026
SRD1Srd1p0.022
SAE2Sae2p0.022
YLR162Whypothetical protein0.021
LEU2Leu2p0.020
ALG14Alg14p0.019
YIR035Chypothetical protein0.019
ADH2Adh2p0.019
YOL038C-Ahypothetical protein0.018
MER1Mer1p0.018
YLR264C-Ahypothetical protein0.018
GYL1Gyl1p0.018
HHT2Hht2p0.018
ZPS1Zps1p0.017
SPL2Spl2p0.016
ARP10Arp10p0.016
SLX4Slx4p0.016
ATP6Atp6p0.016
CSM3Csm3p0.016
HXT3Hxt3p0.016
YPR157Whypothetical protein0.016
YLR042Chypothetical protein0.015
YAR068Whypothetical protein0.015
CDC8Cdc8p0.015
POL2Pol2p0.015
DUN1Dun1p0.015
AUA1Aua1p0.014
POL3Pol3p0.014
CUP1-1Cup1-1p0.014
RAD1Rad1p0.014
SGS1Sgs1p0.014
FMT1Fmt1p0.014
IZH4Izh4p0.014
POB3Pob3p0.014
ARG8Arg8p0.014
CRP1Crp1p0.013
YBR013Chypothetical protein0.013
AQY2Aqy2p0.013
SWC7Swc7p0.013
YOL013W-Ahypothetical protein0.013
HPF1Hpf1p0.013
CPD1Cpd1p0.012
MMS4Mms4p0.012
YKR075Chypothetical protein0.012
EXO1Exo1p0.012
YAL037C-Ahypothetical protein0.012
WSS1Wss1p0.012
YLL053Chypothetical protein0.012
UPS3Ups3p0.012
OPT2Opt2p0.012
BSC1Bsc1p0.012
MGS1Mgs1p0.012
MF(ALPHA)2Mf(alpha)2p0.012
SCM4Scm4p0.012
SMC6Smc6p0.012
DIC1Dic1p0.012
TFA2Tfa2p0.012
YNL234Whypothetical protein0.012
SFT1Sft1p0.012
TYE7Tye7p0.012
YLR040Chypothetical protein0.011
CHA1Cha1p0.011
YAL064Whypothetical protein0.011
YCR102Chypothetical protein0.011
ALT2Alt2p0.011
PTR2Ptr2p0.011
TFA1Tfa1p0.011
YJL181Whypothetical protein0.011
RRN5Rrn5p0.011
YPR096Chypothetical protein0.011
REE1Ree1p0.011
NRG2Nrg2p0.011
RNP1Rnp1p0.011
YGL006W-Ahypothetical protein0.011
YIL151Chypothetical protein0.011
YIR042Chypothetical protein0.011
YAR066Whypothetical protein0.011
YPL067Chypothetical protein0.011
HHF2Hhf2p0.011
YNL033Whypothetical protein0.011
YMR317Whypothetical protein0.011
RFA2Rfa2p0.010
COS12Cos12p0.010
PHO11Pho11p0.010
MFA2Mfa2p0.010
YML003Whypothetical protein0.010
PTI1Pti1p0.010
ENA5Ena5p0.010
TIR3Tir3p0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
swsn-7Protein SWSN-70.029
npp-15Protein NPP-150.027
cdl-1Protein CDL-10.020
lin-9Protein LIN-90.020
aspm-1Protein ASPM-10.018
mcm-3Protein MCM-30.018
C05C10.2Protein C05C10.20.017
npp-9Protein NPP-90.016
knl-1Protein KNL-10.015
W03G9.3Protein W03G9.30.013
F56B3.4Protein F56B3.40.013
mel-28Protein MEL-280.012
lin-5Protein LIN-50.012
pme-1Protein PME-10.011
usp-14Protein USP-140.011
coh-3Protein COH-30.011
D2096.11Protein D2096.110.010
lig-1Protein LIG-10.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Nde1nuclear distribution gene E homolog 1 (A nidulans)0.023
NanogNanog homeobox0.018
Mcm7minichromosome maintenance deficient 7 (S. cerevisiae)0.017
Cdca8cell division cycle associated 80.015
Ssrp1structure specific recognition protein 10.014
Nup85nucleoporin 850.013
Olfml3olfactomedin-like 30.013
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.013
Fam192afamily with sequence similarity 192, member A0.012
Crtapcartilage associated protein0.012
Fstl1follistatin-like 10.011
Mcm3minichromosome maintenance deficient 3 (S. cerevisiae)0.011
Pold2polymerase (DNA directed), delta 2, regulatory subunit0.010
CtcfCCCTC-binding factor0.010
Ppicpeptidylprolyl isomerase C0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism