The network for ' de novo protein folding' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

de novo protein folding

The process of assisting in the folding of a nascent peptide chain into its correct tertiary structure.

Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
STI1Sti1p0.049
SIS1Sis1p0.039
SSA4Ssa4p0.025
BTN2Btn2p0.020
CPR6Cpr6p0.017
YDJ1Ydj1p0.015
AHA1Aha1p0.015
SSA1Ssa1p0.013
FES1Fes1p0.013
SSA2Ssa2p0.012
SSE1Sse1p0.012
SSA3Ssa3p0.012
CUR1Cur1p0.011
SGT2Sgt2p0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
HSPA8heat shock 70kDa protein 81.000
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 11.000
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 11.000
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.997
DNAJA1DnaJ (Hsp40) homolog, subfamily A, member 10.995
AHSA1AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)0.995
HLA-DRB1major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 10.992
HSPH1heat shock 105kDa/110kDa protein 10.988
STIP1stress-induced-phosphoprotein 10.987
FKBP4FK506 binding protein 4, 59kDa0.985
HLA-DMBmajor histocompatibility complex, class II, DM beta0.961
PPIDpeptidylprolyl isomerase D0.922
HSPD1heat shock 60kDa protein 1 (chaperonin)0.912
HLA-DPA1major histocompatibility complex, class II, DP alpha 10.896
HLA-DMAmajor histocompatibility complex, class II, DM alpha0.889
HSPA1Bheat shock 70kDa protein 1B0.874
TCP1t-complex 10.743
HSPA4heat shock 70kDa protein 40.661
PTGES3prostaglandin E synthase 3 (cytosolic)0.579
BAG1BCL2-associated athanogene0.542
PPP5Cprotein phosphatase 5, catalytic subunit0.521
BAG2BCL2-associated athanogene 20.504
CCT4chaperonin containing TCP1, subunit 4 (delta)0.475
LDHAlactate dehydrogenase A0.448
CHORDC1cysteine and histidine-rich domain (CHORD) containing 10.437
HLA-DPB1major histocompatibility complex, class II, DP beta 10.401
DNAJB1DnaJ (Hsp40) homolog, subfamily B, member 10.342
PDIA3protein disulfide isomerase family A, member 30.339
HSPE1heat shock 10kDa protein 1 (chaperonin 10)0.332
DNAJB6DnaJ (Hsp40) homolog, subfamily B, member 60.306
HSPA9heat shock 70kDa protein 9 (mortalin)0.304
STUB1STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase0.290
HLA-DRB5major histocompatibility complex, class II, DR beta 50.268
SUGT1SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)0.235
BAG3BCL2-associated athanogene 30.200
HSPA1Aheat shock 70kDa protein 1A0.193
PDIA4protein disulfide isomerase family A, member 40.150
NACAnascent polypeptide-associated complex alpha subunit0.136
CACYBPcalcyclin binding protein0.115
CDC37cell division cycle 37 homolog (S. cerevisiae)0.075
CXCR4chemokine (C-X-C motif) receptor 40.068
ST13suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)0.063
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.053
C4orf14chromosome 4 open reading frame 140.045
HLA-DRB4major histocompatibility complex, class II, DR beta 40.043
LDHBlactate dehydrogenase B0.038
NPM1nucleophosmin (nucleolar phosphoprotein B23, numatrin)0.031
GADD45Agrowth arrest and DNA-damage-inducible, alpha0.031
HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)0.028
PPA1pyrophosphatase (inorganic) 10.025
CCDC117coiled-coil domain containing 1170.021
DNAJA3DnaJ (Hsp40) homolog, subfamily A, member 30.021
CCT8chaperonin containing TCP1, subunit 8 (theta)0.020
NUDCnuclear distribution gene C homolog (A. nidulans)0.019
P4HBprolyl 4-hydroxylase, beta polypeptide0.018
GTF2Bgeneral transcription factor IIB0.018
EIF3Leukaryotic translation initiation factor 3, subunit L0.017
EEF1B2eukaryotic translation elongation factor 1 beta 20.014
EIF3Eeukaryotic translation initiation factor 3, subunit E0.013
CCT3chaperonin containing TCP1, subunit 3 (gamma)0.012
HLA-DQB1major histocompatibility complex, class II, DQ beta 10.012
HLA-DQA2major histocompatibility complex, class II, DQ alpha 20.012
EIF3Heukaryotic translation initiation factor 3, subunit H0.011
CALRcalreticulin0.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
H2-Eb1histocompatibility 2, class II antigen E beta0.987
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.960
Chordc1cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 10.902
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.891
Hsph1heat shock 105kDa/110kDa protein 10.840
H2-DMahistocompatibility 2, class II, locus DMa0.504
H2-Ab1histocompatibility 2, class II antigen A, beta 10.492
Cd74CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)0.477
Hspa5heat shock protein 50.453
Hspa8heat shock protein 80.382
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.305
H2-Aahistocompatibility 2, class II antigen A, alpha0.227
Iqcb1IQ calmodulin-binding motif containing 10.175
Cacybpcalcyclin binding protein0.089
Stip1stress-induced phosphoprotein 10.084
Hspd1heat shock protein 1 (chaperonin)0.077
Rpgrip1lRpgrip1-like0.075
Nphp4nephronophthisis 4 (juvenile) homolog (human)0.058
Dnajb1DnaJ (Hsp40) homolog, subfamily B, member 10.050
Hspa9heat shock protein 90.049
H2-DMb2histocompatibility 2, class II, locus Mb20.044
Kpna1karyopherin (importin) alpha 10.039
Nphp1nephronophthisis 1 (juvenile) homolog (human)0.031
Mta1metastasis associated 10.029
Hspa4lheat shock protein 4 like0.028
Hspa1bheat shock protein 1B0.025
Ahi1Abelson helper integration site 10.024
Cct6achaperonin containing Tcp1, subunit 6a (zeta)0.021
Pfn2profilin 20.013
Ahsa2AHA1, activator of heat shock protein ATPase homolog 2 (yeast)0.011
Ahsa1AHA1, activator of heat shock protein ATPase homolog 1 (yeast)0.011
Eef1a1eukaryotic translation elongation factor 1 alpha 10.011
Metap1methionyl aminopeptidase 10.011
Cd79bCD79B antigen0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Hspa8heat shock protein 80.989
Hsph1heat shock 105/110 protein 10.979
Hspd1heat shock protein 1 (chaperonin)0.955
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.943
Stip1stress-induced phosphoprotein 10.507
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.357
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.344
RT1-DMbRT1 class II, locus DMb0.291
Dnajb1DnaJ (Hsp40) homolog, subfamily B, member 10.285
Cd74Cd74 molecule, major histocompatibility complex, class II invariant chain0.165
RT1-DaRT1 class II, locus Da0.163
RT1-BaRT1 class II, locus Ba0.161
Dnaja4DnaJ (Hsp40) homolog, subfamily A, member 40.127
RT1-Db1RT1 class II, locus Db10.098
St13suppression of tumorigenicity 130.079
Canxcalnexin0.069
RT1-DMaRT1 class II, locus DMa0.033
Hspb1heat shock protein 10.024
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.023
Cct4chaperonin containing Tcp1, subunit 4 (delta)0.020
Hspa5heat shock protein 50.017
CnbpCCHC-type zinc finger, nucleic acid binding protein0.017
Chordc1cysteine and histidine-rich domain (CHORD)-containing 10.016
Eif4a2eukaryotic translation initiation factor 4A, isoform 20.015
Cct5chaperonin containing Tcp1, subunit 5 (epsilon)0.012
LOC681996similar to AHA1, activator of heat shock 90kDa protein ATPase homolog 10.012
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.012
RT1-BbRT1 class II, locus Bb0.011
Eif2s2eukaryotic translation initiation factor 2, subunit 2 beta0.010
C1qbcomplement component 1, q subcomponent, B chain0.010