The network for 'regulation of melanocyte differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of melanocyte differentiation

Any process that modulates the frequency, rate or extent of melanocyte differentiation.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
hoxb3ahomeo box B3a0.151
disc1disrupted in schizophrenia 10.119
dip2cDIP2 disco-interacting protein 2 homolog C (Drosophila)0.097
tfectranscription factor EC0.053
ltkleukocyte tyrosine kinase0.045
si:ch211-57k11.10si:ch211-57k11.100.041
hmx2H6 family homeobox 20.036
rargaretinoic acid receptor gamma a0.035
trpm7transient receptor potential cation channel, subfamily M, member 70.035
zbtb4zinc finger and BTB domain containing 40.033
rbfox2RNA binding protein, fox-1 homolog (C. elegans) 20.031
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.029
zeb1zinc finger E-box binding homeobox 10.028
arl13bADP-ribosylation factor-like 13b0.028
zmiz1zinc finger, MIZ-type containing 10.027
dachadachshund a0.025
terttelomerase reverse transcriptase0.025
pabpc1bpoly A binding protein, cytoplasmic 1 b0.025
foxo3aforkhead box O3A0.024
LOC100148274hypothetical protein LOC1001482740.022
sheSrc homology 2 domain containing E0.021
acsl1acyl-CoA synthetase long-chain family member 10.021
kctd15apotassium channel tetramerisation domain containing 15a0.019
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.018
nf1aneurofibromin 1a0.018
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.017
axin1axin 10.017
spna2spectrin alpha 20.017
comtacatechol-O-methyltransferase a0.017
skianuclear oncoprotein skia0.016
fzd9bfrizzled homolog 9b0.015
msi2bmusashi homolog 2b (Drosophila)0.015
eif4g3eukaryotic translation initiation factor 4 gamma, 30.014
csf1racolony stimulating factor 1 receptor, a0.014
LOC100536647disintegrin and metalloproteinase domain-containing protein 10-like0.014
lin54lin-54 homolog0.013
gpc4glypican 40.013
stc1lstanniocalcin 1, like0.013
crestincrestin0.013
rc3rabconnectin 30.012
atp7aATPase, Cu++ transporting, alpha polypeptide0.012
lef1lymphocyte enhancer binding factor 10.012
hoxd4ahomeo box D4a0.012
trim8tripartite motif-containing 80.012
axin2axin 2 (conductin, axil)0.012
bmpr2bbone morphogenetic protein receptor, type II b (serine/threonine kinase)0.012
stau1staufen, RNA binding protein, homolog 1 (Drosophila)0.012
crb2acrumbs homolog 2a0.011
rgmaRGM domain family, member A0.011
wu:fb76c12wu:fb76c120.011
robo3roundabout homolog 30.011
ctbp2lC-terminal binding protein 2, like0.011
fam110bfamily with sequence similarity 110, member B0.011
arfip2aADP-ribosylation factor interacting protein 2a0.010
ap2a1adaptor-related protein complex 2, alpha 1 subunit0.010
zgc:158452zgc:1584520.010
mycbmyelocytomatosis oncogene b0.010
pds5bPDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)0.010
ptprsaprotein tyrosine phosphatase, receptor type, s, a0.010
pcsk5bproprotein convertase subtilisin/kexin type 5b0.010
pnp4apurine nucleoside phosphorylase 4a0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Bcl2l11BCL2-like 11 (apoptosis facilitator)1.000
Trp53transformation related protein 531.000
Kitkit oncogene1.000
Tgfb1transforming growth factor, beta 10.971
BaxBCL2-associated X protein0.968
Bcl2B-cell leukemia/lymphoma 20.928
Bak1BCL2-antagonist/killer 10.721
Ptenphosphatase and tensin homolog0.666
Ednrbendothelin receptor type B0.663
Gli3GLI-Kruppel family member GLI30.597
Smad3MAD homolog 3 (Drosophila)0.529
Fgfr1fibroblast growth factor receptor 10.432
Pmaip1phorbol-12-myristate-13-acetate-induced protein 10.345
Pax2paired box gene 20.345
Itgb1integrin beta 1 (fibronectin receptor beta)0.311
Adamts9a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 90.259
Pbx1pre B-cell leukemia transcription factor 10.241
Leprleptin receptor0.239
Apcadenomatosis polyposis coli0.235
Lystlysosomal trafficking regulator0.232
Thrathyroid hormone receptor alpha0.179
Cav1caveolin 1, caveolae protein0.172
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.165
Vhlvon Hippel-Lindau tumor suppressor0.165
CblCasitas B-lineage lymphoma0.149
Ptgs2prostaglandin-endoperoxide synthase 20.118
Il6stinterleukin 6 signal transducer0.107
Ctnnb1catenin (cadherin associated protein), beta 10.097
Cdh11cadherin 110.093
Klf6Kruppel-like factor 60.090
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.085
Mitfmicrophthalmia-associated transcription factor0.075
Ncoa3nuclear receptor coactivator 30.070
Igf1rinsulin-like growth factor I receptor0.065
Ighimmunoglobulin heavy chain complex0.065
Ikzf1IKAROS family zinc finger 10.064
Meox2mesenchyme homeobox 20.064
Pax8paired box gene 80.059
Mdm2transformed mouse 3T3 cell double minute 20.058
Stat3signal transducer and activator of transcription 30.051
Foxf2forkhead box F20.051
Sox10SRY-box containing gene 100.051
Klf7Kruppel-like factor 7 (ubiquitous)0.049
Smarcd1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.048
Smad4MAD homolog 4 (Drosophila)0.046
Adamts20a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 200.043
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.043
Tgfb2transforming growth factor, beta 20.041
SkilSKI-like0.040
Ptch1patched homolog 10.038
Grb10growth factor receptor bound protein 100.035
Nfibnuclear factor I/B0.033
Rararetinoic acid receptor, alpha0.032
Marcksmyristoylated alanine rich protein kinase C substrate0.031
Mn1meningioma 10.030
Bcl2l1BCL2-like 10.030
Wsb1WD repeat and SOCS box-containing 10.030
Igf2insulin-like growth factor 20.027
Thbs1thrombospondin 10.027
Prrx1paired related homeobox 10.027
Sox2SRY-box containing gene 20.027
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.025
Fgfr2fibroblast growth factor receptor 20.024
Adamts1a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10.023
Retret proto-oncogene0.022
Hipk2homeodomain interacting protein kinase 20.022
Pax3paired box gene 30.021
Nfianuclear factor I/A0.021
Efnb2ephrin B20.021
Tbx10T-box 100.020
Zswim6zinc finger, SWIM domain containing 60.020
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.020
Foxg1forkhead box G10.019
Tcf4transcription factor 40.019
Mcl1myeloid cell leukemia sequence 10.019
Wt1Wilms tumor 1 homolog0.017
Gna11guanine nucleotide binding protein, alpha 110.016
Mef2cmyocyte enhancer factor 2C0.016
Irs2insulin receptor substrate 20.016
Rbms3RNA binding motif, single stranded interacting protein0.016
Kdm2blysine (K)-specific demethylase 2B0.015
Col2a1collagen, type II, alpha 10.015
Cyldcylindromatosis (turban tumor syndrome)0.015
Cdk14cyclin-dependent kinase 140.015
Bdnfbrain derived neurotrophic factor0.015
Eya1eyes absent 1 homolog (Drosophila)0.014
Ctgfconnective tissue growth factor0.014
Atp7aATPase, Cu++ transporting, alpha polypeptide0.014
Lepleptin0.014
Cacna2d1calcium channel, voltage-dependent, alpha2/delta subunit 10.013
Hip1huntingtin interacting protein 10.013
Mfn2mitofusin 20.013
Rarbretinoic acid receptor, beta0.013
Kitlkit ligand0.012
Ptprmprotein tyrosine phosphatase, receptor type, M0.012
Nfe2l2nuclear factor, erythroid derived 2, like 20.012
Tshrthyroid stimulating hormone receptor0.012
Gna13guanine nucleotide binding protein, alpha 130.012
Nf1neurofibromatosis 10.012
Nr2f1nuclear receptor subfamily 2, group F, member 10.012
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism