The network for 'pyridine nucleotide metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

pyridine nucleotide metabolic process

The chemical reactions and pathways involving a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.

NameDescriptionProbabilityFunc Analog Organism
TAL1Tal1p0.894
TNA1Tna1p0.735
GND2Gnd2p0.660
ADH3Adh3p0.634
SOL1Sol1p0.634
TKL2Tkl2p0.472
YJL068Chypothetical protein0.464
ALD6Ald6p0.428
YHR112Chypothetical protein0.419
HXK2Hxk2p0.367
GND1Gnd1p0.359
LSC1Lsc1p0.359
PNC1Pnc1p0.359
YEF1Yef1p0.346
IDH2Idh2p0.328
ALD4Ald4p0.320
PET9Pet9p0.280
MCR1Mcr1p0.222
GUT2Gut2p0.221
UTR1Utr1p0.218
BNA5Bna5p0.213
BDH1Bdh1p0.187
PMI40Pmi40p0.185
MDH1Mdh1p0.183
YJL118Whypothetical protein0.152
YCL042Whypothetical protein0.146
SUI2Sui2p0.135
FBA1Fba1p0.135
TAX4Tax4p0.130
GPM2Gpm2p0.130
WWM1Wwm1p0.126
SPE3Spe3p0.126
YKR070Whypothetical protein0.125
SOL3Sol3p0.121
GLO1Glo1p0.116
ADH2Adh2p0.114
PNS1Pns1p0.111
CTT1Ctt1p0.109
AIM45Aim45p0.108
PDC1Pdc1p0.104
ADH5Adh5p0.103
IMD2Imd2p0.098
YPR1Ypr1p0.098
YGR250Chypothetical protein0.097
CAR2Car2p0.095
UGA1Uga1p0.094
HAL1Hal1p0.092
BNA6Bna6p0.091
CPR6Cpr6p0.088
TSA2Tsa2p0.088
SHE2She2p0.086
YPR063Chypothetical protein0.086
NDE1Nde1p0.086
YIH1Yih1p0.084
HAP4Hap4p0.084
URA6Ura6p0.084
YPR172Whypothetical protein0.084
MDH2Mdh2p0.083
HEM15Hem15p0.082
PDC5Pdc5p0.081
ECM31Ecm31p0.079
CPR3Cpr3p0.074
RTC3Rtc3p0.072
GRE3Gre3p0.071
ACO1Aco1p0.070
SIP2Sip2p0.070
PYK2Pyk2p0.069
ENO2Eno2p0.068
LEU4Leu4p0.068
DSD1Dsd1p0.068
YJL218Whypothetical protein0.067
PFK2Pfk2p0.067
ECM4Ecm4p0.067
NQM1Nqm1p0.065
GCY1Gcy1p0.065
TFS1Tfs1p0.064
BNA1Bna1p0.063
FDC1Fdc1p0.062
PRS2Prs2p0.062
PUS6Pus6p0.061
INM2Inm2p0.060
CWP1Cwp1p0.059
MVD1Mvd1p0.059
HOR2Hor2p0.059
HBT1Hbt1p0.059
PDI1Pdi1p0.059
DLD1Dld1p0.058
HUT1Hut1p0.057
YGR001Chypothetical protein0.057
NIT3Nit3p0.056
TRR1Trr1p0.055
IRC7Irc7p0.055
SOL2Sol2p0.055
GAD1Gad1p0.054
COA3Coa3p0.054
ABZ2Abz2p0.053
PMT3Pmt3p0.053
HOT13Hot13p0.053
YLR264C-Ahypothetical protein0.052
YPL088Whypothetical protein0.052
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
PyKPyruvate kinase0.559
Got2Glutamate oxaloacetate transaminase 20.521
EnoEnolase0.518
FdhFormaldehyde dehydrogenase0.294
CG7920CG7920 gene product from transcript CG7920-RA0.263
IdhIsocitrate dehydrogenase0.256
PgdPhosphogluconate dehydrogenase0.244
skapskpA associated protein0.226
AconAconitase0.223
CG42672CG42672 gene product from transcript CG42672-RD0.130
CG30410CG30410 gene product from transcript CG30410-RB0.127
AldhAldehyde dehydrogenase0.113
CG6439CG6439 gene product from transcript CG6439-RA0.107
AprtAdenine phosphoribosyltransferase0.102
PgiPhosphoglucose isomerase0.100
CG3835CG3835 gene product from transcript CG3835-RB0.096
CG13474CG13474 gene product from transcript CG13474-RA0.084
ArgkArginine kinase0.077
ND75NADH:ubiquinone reductase 75kD subunit precursor0.076
CG4390CG4390 gene product from transcript CG4390-RB0.073
vigvasa intronic gene0.073
CG12992CG12992 gene product from transcript CG12992-RB0.070
CG5793CG5793 gene product from transcript CG5793-RA0.065
CG11876CG11876 gene product from transcript CG11876-RA0.060
regucalcinCG1803 gene product from transcript CG1803-RA0.056
l(1)G0334lethal (1) G03340.053
ZwZwischenferment0.047
CG10932CG10932 gene product from transcript CG10932-RA0.046
aayastray0.046
PgmPhosphogluconate mutase0.046
OatOrnithine aminotransferase precursor0.046
CG3902CG3902 gene product from transcript CG3902-RA0.045
MpcpMitochondrial phosphate carrier protein0.044
CG5261CG5261 gene product from transcript CG5261-RB0.042
aldaltered disjunction0.040
CG3662CG3662 gene product from transcript CG3662-RB0.040
Nc73EFNeural conserved at 73EF0.039
CG18745CG18745 gene product from transcript CG18745-RA0.038
Ef1gammaCG11901 gene product from transcript CG11901-RC0.038
CG14290CG14290 gene product from transcript CG14290-RB0.037
CG6776CG6776 gene product from transcript CG6776-RA0.034
CG6332CG6332 gene product from transcript CG6332-RB0.033
CG14204CG14204 gene product from transcript CG14204-RA0.033
CG16719CG16719 gene product from transcript CG16719-RA0.033
CG3731CG3731 gene product from transcript CG3731-RA0.032
MenMalic enzyme0.032
ssp5short spindle 50.031
hafhattifattener0.031
CG30324CG30324 gene product from transcript CG30324-RA0.030
CG6783CG6783 gene product from transcript CG6783-RC0.030
CG7834CG7834 gene product from transcript CG7834-RA0.029
l(1)G0156lethal (1) G01560.029
PHGPxCG12013 gene product from transcript CG12013-RC0.028
CG13747CG13747 gene product from transcript CG13747-RA0.027
CG17597CG17597 gene product from transcript CG17597-RA0.027
CG5059CG5059 gene product from transcript CG5059-RD0.027
CG17083CG17083 gene product from transcript CG17083-RA0.027
CG1707CG1707 gene product from transcript CG1707-RA0.027
CG5214CG5214 gene product from transcript CG5214-RA0.026
CG13989CG13989 gene product from transcript CG13989-RA0.026
CG14740CG14740 gene product from transcript CG14740-RA0.026
mei-217CG33935 gene product from transcript CG33935-RC0.026
CG16926CG16926 gene product from transcript CG16926-RA0.025
CG5966CG5966 gene product from transcript CG5966-RA0.025
CG9577CG9577 gene product from transcript CG9577-RA0.025
SsadhSuccinic semialdehyde dehydrogenase0.025
CG4598CG4598 gene product from transcript CG4598-RA0.024
CG31802CG31802 gene product from transcript CG31802-RA0.024
CG4169CG4169 gene product from transcript CG4169-RA0.024
CG3011CG3011 gene product from transcript CG3011-RA0.023
Ca-alpha1DCa[2+]-channel protein alpha[[1]] subunit D0.023
CG9232CG9232 gene product from transcript CG9232-RA0.023
CG15093CG15093 gene product from transcript CG15093-RB0.023
CG10075CG10075 gene product from transcript CG10075-RA0.023
yellow-g2CG13804 gene product from transcript CG13804-RA0.023
CG14260CG14260 gene product from transcript CG14260-RA0.023
granny-smithgranny smith0.023
Prosbeta5RProteasome beta5R subunit0.022
CG11196CG11196 gene product from transcript CG11196-RA0.022
CG5288CG5288 gene product from transcript CG5288-RA0.021
HisCl1Histamine-gated chloride channel subunit 10.021
CG13868CG13868 gene product from transcript CG13868-RA0.021
eIF4E-4CG10124 gene product from transcript CG10124-RA0.021
CG10749CG10749 gene product from transcript CG10749-RA0.021
CG14402CG14402 gene product from transcript CG14402-RA0.021
CG3609CG3609 gene product from transcript CG3609-RA0.021
CG30178CG30178 gene product from transcript CG30178-RA0.020
Ant2Adenine nucleotide translocase 20.020
ympyellow-emperor0.020
CG33138CG33138 gene product from transcript CG33138-RA0.020
yip2yippee interacting protein 20.020
CG7557CG7557 gene product from transcript CG7557-RA0.020
CG15483CG15483 gene product from transcript CG15483-RA0.020
Smg5CG8954 gene product from transcript CG8954-RA0.020
nvynervy0.020
CG8417CG8417 gene product from transcript CG8417-RA0.020
Glut1Glucose transporter 10.020
Tsp33BTetraspanin 33B0.019
CG5458CG5458 gene product from transcript CG5458-RA0.019
LaspCG3849 gene product from transcript CG3849-RB0.019
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ENO1enolase 1, (alpha)0.435
TPI1triosephosphate isomerase 10.267
ALDOAaldolase A, fructose-bisphosphate0.222
IDH3Aisocitrate dehydrogenase 3 (NAD+) alpha0.221
PGK1phosphoglycerate kinase 10.211
UQCRC1ubiquinol-cytochrome c reductase core protein I0.204
GPIglucose-6-phosphate isomerase0.200
IDH3Gisocitrate dehydrogenase 3 (NAD+) gamma0.134
ND1NADH dehydrogenase, subunit 1 (complex I)0.129
TKTtransketolase0.108
ALDH1A1aldehyde dehydrogenase 1 family, member A10.082
ALDH2aldehyde dehydrogenase 2 family (mitochondrial)0.066
GRPEL1GrpE-like 1, mitochondrial (E. coli)0.058
SLC25A11solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 110.055
HIGD2AHIG1 hypoxia inducible domain family, member 2A0.050
MDH2malate dehydrogenase 2, NAD (mitochondrial)0.047
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.044
BBS1Bardet-Biedl syndrome 10.044
PTNpleiotrophin0.041
LDHAlactate dehydrogenase A0.035
GOT1glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)0.033
AGXT2alanine--glyoxylate aminotransferase 20.032
ACO2aconitase 2, mitochondrial0.031
ATP5DATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit0.027
NDUFV1NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa0.026
GLAgalactosidase, alpha0.026
VPS28vacuolar protein sorting 28 homolog (S. cerevisiae)0.025
ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.022
PPIFpeptidylprolyl isomerase F0.022
CYC1cytochrome c-10.019
TXN2thioredoxin 20.018
HSPB1heat shock 27kDa protein 10.018
ETFBelectron-transfer-flavoprotein, beta polypeptide0.018
SLC25A1solute carrier family 25 (mitochondrial carrier; citrate transporter), member 10.017
AGPSalkylglycerone phosphate synthase0.016
TALDO1transaldolase 10.016
IDH2isocitrate dehydrogenase 2 (NADP+), mitochondrial0.016
ECHDC1enoyl CoA hydratase domain containing 10.015
COX8Acytochrome c oxidase subunit VIIIA (ubiquitous)0.015
GPX4glutathione peroxidase 4 (phospholipid hydroperoxidase)0.014
OGDHoxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)0.014
PKM2pyruvate kinase, muscle0.014
SUCLA2succinate-CoA ligase, ADP-forming, beta subunit0.014
C9orf16chromosome 9 open reading frame 160.013
IDEinsulin-degrading enzyme0.013
TSPOtranslocator protein (18kDa)0.013
NFIL3nuclear factor, interleukin 3 regulated0.013
FTLferritin, light polypeptide0.012
BCKDKbranched chain ketoacid dehydrogenase kinase0.012
PGDphosphogluconate dehydrogenase0.012
SDHAsuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.012
ECI1enoyl-CoA delta isomerase 10.011
GCH1GTP cyclohydrolase 10.011
CAPNS1calpain, small subunit 10.011
LOC729020rcRPE0.011
PORP450 (cytochrome) oxidoreductase0.011
SOD2superoxide dismutase 2, mitochondrial0.010
IFITM3interferon induced transmembrane protein 3 (1-8U)0.010
ME2malic enzyme 2, NAD(+)-dependent, mitochondrial0.010
HCCSholocytochrome c synthase0.010
PEMTphosphatidylethanolamine N-methyltransferase0.010
BBS7Bardet-Biedl syndrome 70.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Pnp2purine-nucleoside phosphorylase 20.549
Gpi1glucose phosphate isomerase 10.293
Aco2aconitase 2, mitochondrial0.157
Cscitrate synthase0.108
Uqcrfs1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.076
Hsd11b1hydroxysteroid 11-beta dehydrogenase 10.068
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 10.063
Pgk1phosphoglycerate kinase 10.060
Pgdphosphogluconate dehydrogenase0.057
Gsta3glutathione S-transferase, alpha 30.046
Aldoaaldolase A, fructose-bisphosphate0.043
Gm5506predicted gene 55060.042
Cyp2b10cytochrome P450, family 2, subfamily b, polypeptide 100.041
Inmtindolethylamine N-methyltransferase0.040
Sult1a1sulfotransferase family 1A, phenol-preferring, member 10.039
Ndufs7NADH dehydrogenase (ubiquinone) Fe-S protein 70.037
Pkm2pyruvate kinase, muscle0.032
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.031
Atp5bATP synthase, H+ transporting mitochondrial F1 complex, beta subunit0.031
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.031
Cyc1cytochrome c-10.031
Ces1dcarboxylesterase 1D0.030
Adh1alcohol dehydrogenase 1 (class I)0.030
Ndufv1NADH dehydrogenase (ubiquinone) flavoprotein 10.029
Cyp4b1cytochrome P450, family 4, subfamily b, polypeptide 10.026
Mdh2malate dehydrogenase 2, NAD (mitochondrial)0.025
Fmo5flavin containing monooxygenase 50.025
Taldo1transaldolase 10.023
Ndufs2NADH dehydrogenase (ubiquinone) Fe-S protein 20.022
Cyp2f2cytochrome P450, family 2, subfamily f, polypeptide 20.022
Aldh1a1aldehyde dehydrogenase family 1, subfamily A10.022
Ldhalactate dehydrogenase A0.021
Pfklphosphofructokinase, liver, B-type0.020
Tkttransketolase0.020
Ndufs1NADH dehydrogenase (ubiquinone) Fe-S protein 10.018
Immtinner membrane protein, mitochondrial0.017
Aldh1a7aldehyde dehydrogenase family 1, subfamily A70.016
Sepn1selenoprotein N, 10.016
Gsrglutathione reductase0.016
Gstm1glutathione S-transferase, mu 10.016
Sirt3sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae)0.016
Aox1aldehyde oxidase 10.016
Fh1fumarate hydratase 10.015
G6pdxglucose-6-phosphate dehydrogenase X-linked0.015
Fabp1fatty acid binding protein 1, liver0.014
Thrspthyroid hormone responsive SPOT14 homolog (Rattus)0.014
Dpep1dipeptidase 1 (renal)0.013
Pdha1pyruvate dehydrogenase E1 alpha 10.013
Sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.013
Hsd3b7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 70.013
H6pdhexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)0.013
Rbp4retinol binding protein 4, plasma0.012
Ndufa10NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 100.012
Got1glutamate oxaloacetate transaminase 1, soluble0.012
Trap1TNF receptor-associated protein 10.011
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.011
Fasnfatty acid synthase0.011
Gckrglucokinase regulatory protein0.011
Acsl1acyl-CoA synthetase long-chain family member 10.011
Fmo1flavin containing monooxygenase 10.011
Hadhhydroxyacyl-Coenzyme A dehydrogenase0.011
Mdh1malate dehydrogenase 1, NAD (soluble)0.010
Slc25a5solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 50.010
Dlstdihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)0.010
Vdac2voltage-dependent anion channel 20.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Tpi1triosephosphate isomerase 10.241
Slc25a3solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 30.158
LOC1003636626-phosphogluconate dehydrogenase, decarboxylating-like0.131
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.098
Pgk1phosphoglycerate kinase 10.089
Prdx3peroxiredoxin 30.085
Mdh2malate dehydrogenase 2, NAD (mitochondrial)0.066
Atp5c1ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 10.065
Eno1enolase 1, (alpha)0.046
TufmTu translation elongation factor, mitochondrial0.044
Uqcrfs1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.041
Dnase1l3deoxyribonuclease 1-like 30.040
Aco2aconitase 2, mitochondrial0.038
Sult1a1sulfotransferase family, cytosolic, 1A, phenol-preferring, member 10.034
Fh1fumarate hydratase 10.030
Atp5bATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.025
Got2glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)0.025
Fmo3flavin containing monooxygenase 30.023
Sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.020
Tkttransketolase0.019
Mtch2mitochondrial carrier homolog 2 (C. elegans)0.019
Galmgalactose mutarotase (aldose 1-epimerase)0.017
Otcornithine carbamoyltransferase0.016
Kynukynureninase (L-kynurenine hydrolase)0.016
Ndufv1NADH dehydrogenase (ubiquinone) flavoprotein 10.016
Timm17atranslocase of inner mitochondrial membrane 17 homolog A (yeast)0.016
AuhAU RNA binding protein/enoyl-coenzyme A hydratase0.016
Spp2secreted phosphoprotein 20.015
Haao3-hydroxyanthranilate 3,4-dioxygenase0.014
Fasnfatty acid synthase0.013
Slc25a39solute carrier family 25, member 390.013
Alas1aminolevulinate, delta-, synthase 10.013
Mfn2mitofusin 20.013
Acadsacyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain0.013
Acsm5acyl-CoA synthetase medium-chain family member 50.013
Vdac1voltage-dependent anion channel 10.012
Nmt1N-myristoyltransferase 10.012
Cox5acytochrome c oxidase, subunit Va0.012
Pgm1phosphoglucomutase 10.012
Srxn1sulfiredoxin 1 homolog (S. cerevisiae)0.012
Hadhbhydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit0.012
Agpat21-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)0.012
Trap1TNF receptor-associated protein 10.012
Suclg1succinate-CoA ligase, alpha subunit0.012
Syap1synapse associated protein 10.011
Oplah5-oxoprolinase (ATP-hydrolysing)0.011
Dhcr77-dehydrocholesterol reductase0.011
Uqcrc2ubiquinol cytochrome c reductase core protein 20.011
Atp5g3ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)0.011
Dlatdihydrolipoamide S-acetyltransferase0.011
Slc25a12solute carrier family 25 (mitochondrial carrier, Aralar), member 120.011
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.011
LOC100366121rCG29408-like0.011
Mosc1MOCO sulphurase C-terminal domain containing 10.011
Pkm2pyruvate kinase, muscle0.011
Got1glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)0.011
Gstt3glutathione S-transferase, theta 30.010
Aldh16a1aldehyde dehydrogenase 16 family, member A10.010
Leng4leukocyte receptor cluster (LRC) member 40.010
Pdhbpyruvate dehydrogenase (lipoamide) beta0.010
Gnmtglycine N-methyltransferase0.010