The network for 'blood vessel morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

blood vessel morphogenesis

The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.

NameDescriptionProbabilityFunc Analog Organism
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
shhasonic hedgehog a1.000
efnb2aephrin B2a1.000
cxcr4achemokine (C-X-C motif) receptor 4a0.998
notch3notch homolog 30.998
fn1fibronectin 10.992
gata2aGATA-binding protein 2a0.992
sulf1sulfatase 10.990
nrarpanotch-regulated ankyrin repeat protein a0.987
kdrlkinase insert domain receptor like0.986
dll4delta-like 4 (Drosophila)0.985
dlcdeltaC0.981
fgfrl1bfibroblast growth factor receptor-like 1b0.980
plcg1phospholipase C, gamma 10.977
vegfcvascular endothelial growth factor c0.977
nrp1aneuropilin 1a0.974
edn1endothelin 10.974
ccm2cerebral cavernous malformation 20.968
alcamaactivated leukocyte cell adhesion molecule a0.963
bmp2bbone morphogenetic protein 2b0.962
tbx1T-box 10.959
jag2jagged 20.953
emx3empty spiracles homeobox 30.952
sox7SRY-box containing gene 70.950
cdh5cadherin 50.945
ndr2nodal-related 20.942
spry4sprouty (Drosophila) homolog 40.930
traf4atnf receptor-associated factor 4a0.928
evx1even-skipped homeobox 10.925
ets1av-ets erythroblastosis virus E26 oncogene homolog 1a0.920
dlbdeltaB0.918
tie2endothelium-specific receptor tyrosine kinase 20.915
si:ch211-235f6.2si:ch211-235f6.20.915
tp53tumor protein p530.910
dlddeltaD0.908
hand2heart and neural crest derivatives expressed transcript 20.905
sox2SRY-box containing gene 20.899
pax7apaired box gene 7a0.898
lmx1b.1LIM homeobox transcription factor 1, beta 10.887
krit1KRIT1, ankyrin repeat containing0.884
bocbrother of CDO0.882
cyp26b1cytochrome P450, family 26, subfamily b, polypeptide 10.882
tagln2transgelin 20.882
twist3twist30.879
etv2ets variant gene 20.877
gng2guanine nucleotide binding protein (G protein), gamma 20.873
ptgs1prostaglandin-endoperoxide synthase 10.869
fbn2bfibrillin 2b0.869
aldh1a2aldehyde dehydrogenase 1 family, member A20.866
mibmind bomb0.865
tbx16T-box gene 160.865
wnt11rwingless-type MMTV integration site family, member 11, related0.864
pitx3paired-like homeodomain transcription factor 30.862
pak2ap21 (CDKN1A)-activated kinase 2a0.854
grnagranulin a0.852
runx1runt-related transcription factor 10.841
fli1afriend leukemia integration 1a0.841
cdx4caudal type homeo box transcription factor 40.829
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.826
rargaretinoic acid receptor gamma a0.824
wu:fv91b12wu:fv91b120.820
hoxb2ahomeo box B2a0.818
LOC100000687signal peptide, CUB and EGF-like domain-containing protein 3-like0.816
si:ch211-212m21.5si:ch211-212m21.50.816
notch2notch homolog 20.807
lamb1alaminin, beta 1a0.805
unc45aunc-45 homolog A (C. elegans)0.800
sarsseryl-tRNA synthetase0.799
flt4fms-related tyrosine kinase 40.797
igfbp3insulin-like growth factor binding protein 30.795
sox9bSRY-box containing gene 9b0.790
tal1T-cell acute lymphocytic leukemia 10.784
gli2aGLI-Kruppel family member GLI2a0.775
cxcl12bchemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)0.774
elmo1engulfment and cell motility 1 (ced-12 homolog, C. elegans)0.773
nrp2bneuropilin 2b0.770
snx1sorting nexin 10.768
vegfaavascular endothelial growth factor Aa0.764
her9hairy-related 90.760
wnt3awingless-type MMTV integration site family, member 3A0.756
neurog1neurogenin 10.754
cyp1acytochrome P450, family 1, subfamily A0.751
runx2brunt-related transcription factor 2b0.747
ephb4aeph receptor B4a0.746
gli1GLI-Kruppel family member 10.745
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.743
her11hairy-related 110.740
tbx2aT-box gene 2a0.740
gro2groucho 20.739
lmo4aLIM domain only 4a0.735
chdchordin0.734
spawsouthpaw0.732
spns2spinster homolog 2 (Drosophila)0.732
pcdh18bprotocadherin 18b0.730
sox1aSRY-box containing gene 1a0.727
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.727
hapln3hyaluronan and proteoglycan link protein 30.725
sulf2sulfatase 20.723
ephb4beph receptor B4b0.719
pea3ETS-domain transcription factor pea30.696
hey1hairy/enhancer-of-split related with YRPW motif 10.690
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide1.000
CAV1caveolin 1, caveolae protein, 22kDa1.000
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)1.000
EGFRepidermal growth factor receptor0.995
JAG1jagged 10.992
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.992
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.991
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.990
NRP1neuropilin 10.988
NR4A1nuclear receptor subfamily 4, group A, member 10.987
PTPN1protein tyrosine phosphatase, non-receptor type 10.986
THBS1thrombospondin 10.984
CREBBPCREB binding protein0.980
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.971
NOTCH1notch 10.969
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.968
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.966
FHL2four and a half LIM domains 20.965
FGFR1fibroblast growth factor receptor 10.964
SKILSKI-like oncogene0.963
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.959
EP300E1A binding protein p3000.950
CALM1calmodulin 1 (phosphorylase kinase, delta)0.948
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.942
FGFR2fibroblast growth factor receptor 20.937
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.936
FN1fibronectin 10.932
COL4A2collagen, type IV, alpha 20.926
TIMP3TIMP metallopeptidase inhibitor 30.915
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.910
VEGFAvascular endothelial growth factor A0.909
ENGendoglin0.906
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.906
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.906
LATlinker for activation of T cells0.903
SMAD2SMAD family member 20.902
PTENphosphatase and tensin homolog0.901
FASFas (TNF receptor superfamily, member 6)0.898
ARandrogen receptor0.892
CYR61cysteine-rich, angiogenic inducer, 610.880
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.876
COL5A1collagen, type V, alpha 10.868
CAV2caveolin 20.867
METmet proto-oncogene (hepatocyte growth factor receptor)0.864
NOTCH3notch 30.859
ZFP36zinc finger protein 36, C3H type, homolog (mouse)0.853
SMAD3SMAD family member 30.849
PAX3paired box 30.847
TEKTEK tyrosine kinase, endothelial0.845
MDM2Mdm2 p53 binding protein homolog (mouse)0.842
HOXB5homeobox B50.840
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.831
COL4A1collagen, type IV, alpha 10.821
CCR5chemokine (C-C motif) receptor 50.808
A2Malpha-2-macroglobulin0.806
JUNjun proto-oncogene0.794
CD34CD34 molecule0.790
CDH5cadherin 5, type 2 (vascular endothelium)0.790
STRN3striatin, calmodulin binding protein 30.787
FOSFBJ murine osteosarcoma viral oncogene homolog0.780
CALD1caldesmon 10.766
CTGFconnective tissue growth factor0.766
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.758
DUSP1dual specificity phosphatase 10.756
RAMP2receptor (G protein-coupled) activity modifying protein 20.754
RAMP3receptor (G protein-coupled) activity modifying protein 30.754
SMAD7SMAD family member 70.748
NID1nidogen 10.748
TAL1T-cell acute lymphocytic leukemia 10.732
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.715
BRCA1breast cancer 1, early onset0.711
VEGFCvascular endothelial growth factor C0.702
FGF1fibroblast growth factor 1 (acidic)0.701
PLCG1phospholipase C, gamma 10.700
E2F7E2F transcription factor 70.693
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.689
TCF4transcription factor 40.686
ELNelastin0.679
TGFB1transforming growth factor, beta 10.672
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.665
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.665
BGNbiglycan0.665
COL1A2collagen, type I, alpha 20.651
PMLpromyelocytic leukemia0.649
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.647
CXCL2chemokine (C-X-C motif) ligand 20.635
TP53tumor protein p530.634
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.631
FOSBFBJ murine osteosarcoma viral oncogene homolog B0.626
NRP2neuropilin 20.624
EPAS1endothelial PAS domain protein 10.613
MEF2Cmyocyte enhancer factor 2C0.601
PBX1pre-B-cell leukemia homeobox 10.596
IGFBP5insulin-like growth factor binding protein 50.595
FAF1Fas (TNFRSF6) associated factor 10.594
FGAfibrinogen alpha chain0.594
SPARCsecreted protein, acidic, cysteine-rich (osteonectin)0.593
ITGB5integrin, beta 50.590
PRRX1paired related homeobox 10.577
ILKintegrin-linked kinase0.562
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Vegfavascular endothelial growth factor A1.000
Jag1jagged 10.998
Gata4GATA binding protein 40.998
Pax3paired box gene 30.998
Hand2heart and neural crest derivatives expressed transcript 20.997
Acvr1activin A receptor, type 10.996
Fgfr1fibroblast growth factor receptor 10.996
Smad3MAD homolog 3 (Drosophila)0.995
Smad6MAD homolog 6 (Drosophila)0.994
Shhsonic hedgehog0.993
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.993
Fgfr2fibroblast growth factor receptor 20.992
Nos3nitric oxide synthase 3, endothelial cell0.992
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.990
Bmp4bone morphogenetic protein 40.989
Csf1colony stimulating factor 1 (macrophage)0.988
Ntf3neurotrophin 30.987
Gata6GATA binding protein 60.985
Prrx1paired related homeobox 10.985
Ptpn11protein tyrosine phosphatase, non-receptor type 110.985
Tgfb2transforming growth factor, beta 20.985
Tcfap2atranscription factor AP-2, alpha0.981
Hoxa1homeobox A10.981
Nrp1neuropilin 10.977
Prrx2paired related homeobox 20.971
Runx2runt related transcription factor 20.970
Twist2twist homolog 2 (Drosophila)0.968
Smad4MAD homolog 4 (Drosophila)0.968
Hoxd13homeobox D130.968
Foxc1forkhead box C10.967
Bmpr1abone morphogenetic protein receptor, type 1A0.967
Retret proto-oncogene0.966
Cav1caveolin 1, caveolae protein0.966
Tbx3T-box 30.964
Pax1paired box gene 10.964
Fzd1frizzled homolog 1 (Drosophila)0.959
Otx2orthodenticle homolog 2 (Drosophila)0.959
Gli2GLI-Kruppel family member GLI20.958
Epas1endothelial PAS domain protein 10.958
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.957
Pax2paired box gene 20.955
Pthlhparathyroid hormone-like peptide0.951
Ptgs2prostaglandin-endoperoxide synthase 20.950
Hif1ahypoxia inducible factor 1, alpha subunit0.949
Gli3GLI-Kruppel family member GLI30.949
Grb10growth factor receptor bound protein 100.947
Sox7SRY-box containing gene 70.945
Snai1snail homolog 1 (Drosophila)0.943
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.940
Nodalnodal0.939
Ror1receptor tyrosine kinase-like orphan receptor 10.937
Egfrepidermal growth factor receptor0.937
Hes1hairy and enhancer of split 1 (Drosophila)0.936
Ascl1achaete-scute complex homolog 1 (Drosophila)0.935
Foxf1aforkhead box F1a0.932
Nognoggin0.932
Gdnfglial cell line derived neurotrophic factor0.931
Fgf8fibroblast growth factor 80.929
Cxcl12chemokine (C-X-C motif) ligand 120.928
Fgfr3fibroblast growth factor receptor 30.926
Notch1Notch gene homolog 1 (Drosophila)0.925
Ptk7PTK7 protein tyrosine kinase 70.925
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.923
Efnb2ephrin B20.922
Acvrl1activin A receptor, type II-like 10.922
Adamts1a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10.921
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.921
Tgfbr2transforming growth factor, beta receptor II0.918
Col4a1collagen, type IV, alpha 10.915
Cdh5cadherin 50.914
Tcf21transcription factor 210.914
Sox2SRY-box containing gene 20.913
Foxc2forkhead box C20.910
Ctnnb1catenin (cadherin associated protein), beta 10.909
Zic3zinc finger protein of the cerebellum 30.909
Ror2receptor tyrosine kinase-like orphan receptor 20.906
Cyr61cysteine rich protein 610.899
Mrc2mannose receptor, C type 20.896
Wt1Wilms tumor 1 homolog0.896
Ccr2chemokine (C-C motif) receptor 20.894
Kdrkinase insert domain protein receptor0.893
Hand1heart and neural crest derivatives expressed transcript 10.892
Pbx1pre B-cell leukemia transcription factor 10.891
Ccl2chemokine (C-C motif) ligand 20.888
Apoeapolipoprotein E0.887
Ptk2PTK2 protein tyrosine kinase 20.885
Adra2badrenergic receptor, alpha 2b0.882
Adrb1adrenergic receptor, beta 10.879
Pitx2paired-like homeodomain transcription factor 20.879
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.875
Vangl2vang-like 2 (van gogh, Drosophila)0.875
Hoxc6homeobox C60.871
Ednrbendothelin receptor type B0.869
Arntlaryl hydrocarbon receptor nuclear translocator-like0.869
Pax6paired box gene 60.868
Runx1runt related transcription factor 10.866
Pcdh12protocadherin 120.866
Hic1hypermethylated in cancer 10.865
Tbx2T-box 20.865
Emx1empty spiracles homolog 1 (Drosophila)0.864
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Lamc1laminin, gamma 10.756
Fgfr2fibroblast growth factor receptor 20.656
Utrnutrophin0.553
Col12a1collagen, type XII, alpha 10.552
Mbl1mannose-binding lectin (protein A) 10.515
Cd4Cd4 molecule0.506
Calcrlcalcitonin receptor-like0.492
Tgfbr2transforming growth factor, beta receptor II0.423
Csf1colony stimulating factor 1 (macrophage)0.403
Ccl2chemokine (C-C motif) ligand 20.382
Ccl4chemokine (C-C motif) ligand 40.378
Nos3nitric oxide synthase 3, endothelial cell0.369
Pecam1platelet/endothelial cell adhesion molecule 10.362
Itga6integrin, alpha 60.321
Ptafrplatelet-activating factor receptor0.305
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.296
Jak1Janus kinase 10.293
Id3inhibitor of DNA binding 30.286
Slco2b1solute carrier organic anion transporter family, member 2b10.280
Il9rinterleukin 9 receptor0.265
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.264
Tpsab1tryptase alpha/beta 10.256
Timp3TIMP metallopeptidase inhibitor 30.254
Mmp10matrix metallopeptidase 100.243
Il1binterleukin 1 beta0.237
Lims1LIM and senescent cell antigen-like domains 10.237
Ngfnerve growth factor (beta polypeptide)0.234
Cpxm2carboxypeptidase X (M14 family), member 20.234
Mcammelanoma cell adhesion molecule0.221
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.212
Il1r1interleukin 1 receptor, type I0.210
Cdh5cadherin 50.209
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.205
Igfbp5insulin-like growth factor binding protein 50.203
Metmet proto-oncogene0.203
Thbdthrombomodulin0.202
Il8rbinterleukin 8 receptor, beta0.202
Cd200r1CD200 receptor 10.200
F13a1coagulation factor XIII, A1 polypeptide0.200
Ccr2chemokine (C-C motif) receptor 20.197
Trim47tripartite motif-containing 470.192
Cav1caveolin 1, caveolae protein0.188
Prrx1paired related homeobox 10.180
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.179
Col4a1collagen, type IV, alpha 10.178
Sox17SRY (sex determining region Y)-box 170.172
TekTEK tyrosine kinase, endothelial0.169
Itpr2inositol 1,4,5-triphosphate receptor, type 20.165
Ccl3chemokine (C-C motif) ligand 30.163
Smgbneonatal submandibular gland protein B0.161
Smad1SMAD family member 10.159
Edn1endothelin 10.157
Fgfr1Fibroblast growth factor receptor 10.156
Il7interleukin 70.152
Kdrkinase insert domain receptor0.151
Emcnendomucin0.149
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.147
Hpxhemopexin0.144
Pxdnperoxidasin homolog (Drosophila)0.143
Napsanapsin A aspartic peptidase0.143
Gcgroup specific component0.142
Tacr1tachykinin receptor 10.137
Kcnj8potassium inwardly-rectifying channel, subfamily J, member 80.137
Plekhg2pleckstrin homology domain containing, family G (with RhoGef domain) member 20.133
MdficMyoD family inhibitor domain containing0.132
Irs1insulin receptor substrate 10.130
Bglapbone gamma-carboxyglutamate (gla) protein0.130
Galgalanin prepropeptide0.130
Bst1bone marrow stromal cell antigen 10.130
Arntaryl hydrocarbon receptor nuclear translocator0.127
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.125
Elf1E74-like factor 10.123
Reg1aregenerating islet-derived 1 alpha0.123
Cald1caldesmon 10.120
Itgamintegrin, alpha M0.120
Ahsgalpha-2-HS-glycoprotein0.119
Pld2phospholipase D20.115
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.114
Npr3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)0.113
Prkchprotein kinase C, eta0.112
Mllt4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.110
Nr4a3nuclear receptor subfamily 4, group A, member 30.108
Myo1cmyosin IC0.108
Acvrl1activin A receptor type II-like 10.106
Ankrd1ankyrin repeat domain 1 (cardiac muscle)0.106
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.106
Actn4actinin alpha 40.105
Gabrg3gamma-aminobutyric acid (GABA) A receptor, gamma 30.105
P2rx2purinergic receptor P2X, ligand-gated ion channel, 20.105
Plxnd1plexin D10.104
Cd14CD14 molecule0.102
Crisp1cysteine-rich secretory protein 10.102
Il1rninterleukin 1 receptor antagonist0.102
Klf4Kruppel-like factor 4 (gut)0.101
Notch2Notch homolog 2 (Drosophila)0.099
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.099
Mmp2matrix metallopeptidase 20.098
Iappislet amyloid polypeptide0.098
Cd38CD38 molecule0.097
Arhgef15Rho guanine nucleotide exchange factor (GEF) 150.096