The network for 'pyrimidine containing compound metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

pyrimidine containing compound metabolic process

The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.

NameDescriptionProbabilityFunc Analog Organism
THI20Thi20p0.925
THI2Thi2p0.904
THI3Thi3p0.838
RRP1Rrp1p0.415
THI13Thi13p0.413
YNL010Whypothetical protein0.289
THI5Thi5p0.264
URA5Ura5p0.261
DFR1Dfr1p0.227
PET18Pet18p0.200
THI12Thi12p0.179
THI73Thi73p0.178
THI21Thi21p0.175
PMI40Pmi40p0.164
ERB1Erb1p0.159
ALG14Alg14p0.145
DAS2Das2p0.144
YEL073Chypothetical protein0.137
GUK1Guk1p0.134
TAD3Tad3p0.126
YAH1Yah1p0.123
RPB8Rpb8p0.117
INM1Inm1p0.113
THI11Thi11p0.113
SNZ2Snz2p0.107
MDN1Mdn1p0.107
BNA2Bna2p0.105
MNE1Mne1p0.104
DPH5Dph5p0.104
THI6Thi6p0.103
TUB3Tub3p0.099
IMD2Imd2p0.097
PRS1Prs1p0.093
PDC2Pdc2p0.092
YFL040Whypothetical protein0.089
THG1Thg1p0.085
SIL1Sil1p0.083
GIT1Git1p0.082
YNL024Chypothetical protein0.081
TMA20Tma20p0.078
FUS3Fus3p0.078
RMA1Rma1p0.078
SPE4Spe4p0.074
YMR321Chypothetical protein0.074
URA3Ura3p0.072
SQT1Sqt1p0.067
HLR1Hlr1p0.066
NOP7Nop7p0.064
NUC1Nuc1p0.064
SNO3Sno3p0.062
YGK3Ygk3p0.060
KTI12Kti12p0.060
YDL157Chypothetical protein0.060
SRD1Srd1p0.058
AAD14Aad14p0.057
YDR370Chypothetical protein0.057
URA4Ura4p0.056
YPR127Whypothetical protein0.056
YOL038C-Ahypothetical protein0.056
YGR201Chypothetical protein0.055
NIP7Nip7p0.055
POM34Pom34p0.055
GYL1Gyl1p0.054
YPL245Whypothetical protein0.053
YDR341Chypothetical protein0.053
RBG2Rbg2p0.053
ZPS1Zps1p0.052
TCA17Tca17p0.052
YLR264C-Ahypothetical protein0.052
YIR035Chypothetical protein0.051
YNL108Chypothetical protein0.051
YLR042Chypothetical protein0.051
IRC23Irc23p0.051
URA2Ura2p0.051
PSF2Psf2p0.050
SNO2Sno2p0.050
THI4Thi4p0.049
SSP1Ssp1p0.049
DBP5Dbp5p0.049
HTS1Hts1p0.049
ACM1Acm1p0.048
MF(ALPHA)2Mf(alpha)2p0.048
PCK1Pck1p0.048
ARP10Arp10p0.047
KTR5Ktr5p0.047
YEH2Yeh2p0.047
REX2Rex2p0.046
ADH2Adh2p0.046
CLB6Clb6p0.046
AIM20Aim20p0.046
YLR126Chypothetical protein0.045
LEU2Leu2p0.045
SEN2Sen2p0.045
DTD1Dtd1p0.045
RKI1Rki1p0.045
YET2Yet2p0.044
YAR023Chypothetical protein0.044
PMT3Pmt3p0.043
TAE1Tae1p0.042
YGR079Whypothetical protein0.042
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
nrf-5Protein NRF-50.010
sar-1Protein SAR-10.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
dhfrdihydrofolate reductase0.314
mthfd1methylenetetrahydrofolate dehydrogenase (NADP+ dependent)0.126
mki67ipmki67 (FHA domain) interacting nucleolar phosphoprotein (human)0.123
mtr5-methyltetrahydrofolate-homocysteine methyltransferase0.105
ddx56DEAD (Asp-Glu-Ala-Asp) box polypeptide 560.094
tymsthymidylate synthase0.093
pold1polymerase (DNA directed), delta 1, catalytic subunit0.089
si:dkey-91i17.1si:dkey-91i17.10.084
zgc:110847zgc:1108470.077
si:dkey-1h6.1si:dkey-1h6.10.075
dnmt1DNA (cytosine-5-)-methyltransferase 10.074
mapk3mitogen-activated protein kinase 30.071
mthfd2lmethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like0.068
slc25a32asolute carrier family 25, member 32a0.066
rfc4replication factor C (activator 1) 40.066
surf6surfeit 60.065
pola2polymerase (DNA directed), alpha 20.064
prim1primase polypeptide 10.062
im:7148292im:71482920.060
mthfd2methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase0.058
nop58NOP58 ribonucleoprotein homolog (yeast)0.052
fblfibrillarin0.048
rrs1RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)0.045
wdr75WD repeat domain 750.045
zff9zinc finger protein 90.044
nup43nucleoporin 430.044
hspd1heat shock 60kD protein 1 (chaperonin)0.041
hellshelicase, lymphoid-specific0.039
rfc3replication factor C (activator 1) 30.038
kpna2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.038
aldh4a1aldehyde dehydrogenase 4 family, member A10.036
ddx18DEAD (Asp-Glu-Ala-Asp) box polypeptide 180.033
trmt2atrm2 tRNA methyltransferase 2 homolog A (S. cerevisiae)0.033
im:6898523im:68985230.032
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.032
pgm3phosphoglucomutase 30.031
zgc:56683zgc:566830.030
pprc1peroxisome proliferator-activated receptor gamma, coactivator-related 10.030
aldh7a1aldehyde dehydrogenase 7 family, member A10.029
slc25a32bsolute carrier family 25, member 32b0.029
wdr12WD repeat domain 120.027
rpl7l1ribosomal protein L7-like 10.026
pdss1prenyl (decaprenyl) diphosphate synthase, subunit 10.026
celsr1bcadherin EGF LAG seven-pass G-type receptor 1b0.025
etf1eukaryotic translation termination factor 10.025
byslbystin-like0.025
noc4lnucleolar complex associated 4 homolog (S. cerevisiae)0.024
mapk12mitogen-activated protein kinase 120.024
mre11ameiotic recombination 11 homolog A (S. cerevisiae)0.023
impdh2IMP (inosine monophosphate) dehydrogenase 20.023
zgc:112986zgc:1129860.022
mak16MAK16 homolog (S. cerevisiae)0.022
nol10nucleolar protein 100.021
prdx2peroxiredoxin 20.021
zgc:152830zgc:1528300.021
ncapg2non-SMC condensin II complex, subunit G20.021
gins1GINS complex subunit 1 (Psf1 homolog)0.020
imp4IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)0.020
noc3lnucleolar complex associated 3 homolog (S. cerevisiae)0.020
mat1amethionine adenosyltransferase I, alpha0.019
dpyddihydropyrimidine dehydrogenase0.019
msh6mutS homolog 6 (E. coli)0.019
pole2polymerase (DNA directed), epsilon 20.019
polr1apolymerase (RNA) I polypeptide A0.019
tomm40ltranslocase of outer mitochondrial membrane 40 homolog, like0.018
dap3death associated protein 30.018
ints6integrator complex subunit 60.018
si:ch211-93f2.1si:ch211-93f2.10.018
ahctf1AT hook containing transcription factor 10.018
smc4structural maintenance of chromosomes 40.017
LOC5675475,10-methylenetetrahydrofolate reductase (NADPH)-like0.017
smc2structural maintenance of chromosomes 20.017
hist1h4lhistone 1, H4, like0.017
zgc:56429zgc:564290.017
lap3leucine aminopeptidase 30.017
snf8SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)0.017
grwd1glutamate-rich WD repeat containing 10.017
fen1flap structure-specific endonuclease 10.017
si:dkey-25e12.5si:dkey-25e12.50.017
nr1h5nuclear receptor subfamily 1, group H, member 50.017
bicc2bicaudal C homolog 20.017
slc10a2solute carrier family 10 (sodium/bile acid cotransporter family), member 20.016
nfe2l1nuclear factor, erythroid derived 2,-like 10.016
gartphosphoribosylglycinamide formyltransferase0.016
pola1polymerase (DNA directed), alpha 10.016
naspnuclear autoantigenic sperm protein (histone-binding)0.016
cyp4t8cytochrome P450, family 4, subfamily T, polypeptide 80.016
cyfip2cytoplasmic FMR1 interacting protein 20.016
mtx1bmetaxin 1b0.016
mapk6mitogen-activated protein kinase 60.015
sypl2asynaptophysin-like 2a0.015
pdia2protein disulfide isomerase family A, member 20.015
si:ch211-89f7.4si:ch211-89f7.40.015
srprsignal recognition particle receptor (docking protein)0.015
sult1st3sulfotransferase family 1, cytosolic sulfotransferase 30.015
acy3.2aspartoacylase (aminocyclase) 3.20.015
rrm1ribonucleotide reductase M1 polypeptide0.015
slc9a3r1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.015
mapk7mitogen-activated protein kinase 70.015
ftcdformiminotransferase cyclodeaminase0.015
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
NME1non-metastatic cells 1, protein (NM23A) expressed in0.440
ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase0.100
NME3non-metastatic cells 3, protein expressed in0.068
NME4non-metastatic cells 4, protein expressed in0.043
NME2non-metastatic cells 2, protein (NM23B) expressed in0.040
SH3GL3SH3-domain GRB2-like 30.028
POLR1Cpolymerase (RNA) I polypeptide C, 30kDa0.025
MAPK3mitogen-activated protein kinase 30.024
POLR2Hpolymerase (RNA) II (DNA directed) polypeptide H0.022
SPG21spastic paraplegia 21 (autosomal recessive, Mast syndrome)0.020
NOP56NOP56 ribonucleoprotein homolog (yeast)0.019
PTPROprotein tyrosine phosphatase, receptor type, O0.017
MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor)0.016
UCK2uridine-cytidine kinase 20.016
GINS3GINS complex subunit 3 (Psf3 homolog)0.015
RPL38ribosomal protein L380.014
MAPK14mitogen-activated protein kinase 140.012
SH3GL2SH3-domain GRB2-like 20.012
WDYHV1WDYHV motif containing 10.011
ECH1enoyl CoA hydratase 1, peroxisomal0.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Chpt1choline phosphotransferase 10.183
Gtf2a1general transcription factor II A, 10.173
Mcm4minichromosome maintenance deficient 4 homolog (S. cerevisiae)0.108
Mapk1mitogen-activated protein kinase 10.098
Tdgthymine DNA glycosylase0.083
Tympthymidine phosphorylase0.075
Sykbspleen tyrosine kinase0.074
Dusp6dual specificity phosphatase 60.068
Atf2activating transcription factor 20.058
Pea15aphosphoprotein enriched in astrocytes 15A0.057
Mapk3mitogen-activated protein kinase 30.045
Lbrlamin B receptor0.044
Nup93nucleoporin 930.041
Fads2fatty acid desaturase 20.040
Ighimmunoglobulin heavy chain complex0.034
Hspa14heat shock protein 140.031
Tfdp1transcription factor Dp 10.030
Pafah1b2platelet-activating factor acetylhydrolase, isoform 1b, subunit 20.024
Nprl3nitrogen permease regulator-like 3 (S. cerevisiae)0.023
Sp3trans-acting transcription factor 30.022
Acad11acyl-Coenzyme A dehydrogenase family, member 110.021
Catcatalase0.021
Srmspermidine synthase0.020
Sqstm1sequestosome 10.019
Mcm7minichromosome maintenance deficient 7 (S. cerevisiae)0.019
Prdm1PR domain containing 1, with ZNF domain0.018
Ptpn22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.018
Siaesialic acid acetylesterase0.018
Mutmethylmalonyl-Coenzyme A mutase0.016
Nupl1nucleoporin like 10.016
Fen1flap structure specific endonuclease 10.016
Snrnp40small nuclear ribonucleoprotein 40 (U5)0.015
Ivdisovaleryl coenzyme A dehydrogenase0.015
D030056L22RikRIKEN cDNA D030056L22 gene0.015
Lancl2LanC (bacterial lantibiotic synthetase component C)-like 20.014
TiprlTIP41, TOR signalling pathway regulator-like (S. cerevisiae)0.014
Esr1estrogen receptor 1 (alpha)0.014
Wdr77WD repeat domain 770.013
Rpa1replication protein A10.013
Ehhadhenoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase0.012
Acadmacyl-Coenzyme A dehydrogenase, medium chain0.012
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.012
Acadsbacyl-Coenzyme A dehydrogenase, short/branched chain0.011
Mknk2MAP kinase-interacting serine/threonine kinase 20.011
Ddx39DEAD (Asp-Glu-Ala-Asp) box polypeptide 390.011
Fbxo8F-box protein 80.010
RoraRAR-related orphan receptor alpha0.010
Slc25a16solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 160.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ns5atp9NS5A (hepatitis C virus) transactivated protein 90.038
Rfc3replication factor C (activator 1) 30.031
Prim1DNA primase, p49 subunit0.031
Nhp2NHP2 ribonucleoprotein homolog (yeast)0.029
Dad1defender against cell death 10.029
Ccnb1cyclin B10.028
Mcm3minichromosome maintenance complex component 30.024
Mcm6minichromosome maintenance complex component 60.022
Dhfrdihydrofolate reductase0.020
Mcm2minichromosome maintenance complex component 20.018
HypkHuntingtin interacting protein K0.018
Pgam1phosphoglycerate mutase 1 (brain)0.018
Stmn1stathmin 10.018
Mcm5minichromosome maintenance complex component 50.018
Fen1flap structure-specific endonuclease 10.017
Dnajc9DnaJ (Hsp40) homolog, subfamily C, member 90.017
Mcm4minichromosome maintenance complex component 40.017
Atp5g1ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)0.017
Cdca7cell division cycle associated 70.016
Pdia6protein disulfide isomerase family A, member 60.016
Rrm1ribonucleotide reductase M10.016
Rsad2radical S-adenosyl methionine domain containing 20.015
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.015
Sec61bSec61 beta subunit0.015
Tomm6translocase of outer mitochondrial membrane 6 homolog (yeast)0.015
Rpl14ribosomal protein L140.015
Snf8SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)0.014
Ube2cubiquitin-conjugating enzyme E2C0.014
Chmp5chromatin modifying protein 50.014
Trip13thyroid hormone receptor interactor 130.014
Rfc4replication factor C (activator 1) 40.013
Bscl2Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)0.013
Fam173afamily with sequence similarity 173, member A0.012
Top2atopoisomerase (DNA) II alpha0.012
Kifc1kinesin family member C10.012
Tcf19transcription factor 190.012
RGD620382Nucleoside 2-deoxyribosyltransferase domain containing protein RGD6203820.012
Ppil3peptidylprolyl isomerase (cyclophilin)-like 30.012
Tk1thymidine kinase 1, soluble0.012
Timelesstimeless homolog (Drosophila)0.012
Grpel1GrpE-like 1, mitochondrial0.012
Byslbystin-like0.011
Tsen34tRNA splicing endonuclease 34 homolog (S. cerevisiae)0.011
Cox8acytochrome c oxidase subunit VIIIa0.011
RGD1562987similar to cDNA sequence BC0311810.011
Apex1APEX nuclease (multifunctional DNA repair enzyme) 10.011
Adhfe1alcohol dehydrogenase, iron containing, 10.011
Hspd1heat shock protein 1 (chaperonin)0.011
Isoc1isochorismatase domain containing 10.010
Mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.010
Hsd17b12hydroxysteroid (17-beta) dehydrogenase 120.010