The network for 'zinc ion homeostasis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

zinc ion homeostasis

Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell.

NameDescriptionProbabilityFunc Analog Organism
OLE1Ole1p0.073
FTH1Fth1p0.046
IZH4Izh4p0.038
IZH2Izh2p0.033
ZRT1Zrt1p0.022
LST4Lst4p0.022
FET5Fet5p0.019
ZRG17Zrg17p0.018
AUR1Aur1p0.018
IZH1Izh1p0.017
ZRT2Zrt2p0.015
ZAP1Zap1p0.015
FAA4Faa4p0.015
AQR1Aqr1p0.014
YOR390Whypothetical protein0.013
SMF2Smf2p0.011
FET4Fet4p0.011
CPR1Cpr1p0.011
PRS2Prs2p0.010
SRD1Srd1p0.010
CHA1Cha1p0.010
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
zgc:113210zgc:1132100.755
rp2retinitis pigmentosa 2 (X-linked recessive)0.290
cdkrap3CDK5 regulatory subunit associated protein 30.201
nrxn3aneurexin 3a0.096
vps18vacuolar protein sorting protein 180.072
eaf1ELL associated factor 10.065
slc39a9solute carrier family 39 (zinc transporter), member 90.061
hsd17b12bhydroxysteroid (17-beta) dehydrogenase 12b0.052
slc30a5solute carrier family 30 (zinc transporter), member 50.046
lgals9l1lectin, galactoside-binding, soluble, 9 (galectin 9)-like 10.046
slc30a6solute carrier family 30 (zinc transporter), member 60.043
slc39a3solute carrier family 39 (zinc transporter), member 30.039
glb1galactosidase, beta 10.038
fanceFanconi anemia, complementation group E0.037
clptm1lcleft lip and palate associated transmembrane protein 1, like0.037
mtmr12myotubularin related protein 120.036
slc39a11solute carrier family 39 (metal ion transporter), member 110.035
slc39a4solute carrier family 39 (zinc transporter), member 40.034
acadmacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain0.034
slc30a9solute carrier family 30 (zinc transporter), member 90.033
inppl1ainositol polyphosphate phosphatase-like 1a0.031
fancfFanconi anemia, complementation group F0.029
lgals2blectin, galactoside-binding, soluble, 2b0.029
trdmt1tRNA aspartic acid methyltransferase 10.024
setdb2SET domain, bifurcated 20.022
mtm1myotubularin 10.021
pgrmc1progesterone receptor membrane component 10.021
slc39a10solute carrier family 39 (zinc transporter), member 100.021
slc39a13solute carrier family 39 (zinc transporter), member 130.020
LOC560606novel protein similar to human and mouse leishmanolysin-like (metallopeptidase M8 family) (LMLN)0.020
rpn2ribophorin II0.020
coq3coenzyme Q3 homolog, methyltransferase (yeast)0.019
adipor1aadiponectin receptor 1a0.018
slc39a1solute carrier family 39 (zinc transporter), member 10.018
fkbp2FK506 binding protein 20.018
eif2c4eukaryotic translation initiation factor 2C, 40.017
sb:eu275sb:eu2750.016
zgc:56136zgc:561360.016
acvr2aactivin receptor IIa0.015
LOC554173abnormal spindles0.015
zgc:110256zgc:1102560.015
eaf2ELL associated factor 20.014
pttg1ipbpituitary tumor-transforming 1 interacting protein b0.014
lnx2bligand of numb-protein X 2b0.014
slc30a7solute carrier family 30 (zinc transporter), member 70.013
LOC572344hypothetical protein LOC5723440.013
eif2c3eukaryotic translation initiation factor 2C, 30.013
slc30a4solute carrier family 30 (zinc transporter), member 40.013
mcfd2multiple coagulation factor deficiency 20.012
stard3START domain containing 30.012
lyzlysozyme0.012
slc39a6solute carrier family 39 (zinc transporter), member 60.012
vcpvalosin containing protein0.011
sod2superoxide dismutase 2, mitochondrial0.011
ech1enoyl CoA hydratase 1, peroxisomal0.011
actr2ARP2 actin-related protein 2 homolog0.011
catcatalase0.011
zgc:92765zgc:927650.011
tm9sf3transmembrane 9 superfamily member 30.011
epoerythropoietin0.011
oclnboccludin b0.011
blmBloom syndrome0.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CatCatalase0.253
parkparkin0.073
washwashout0.063
moimodigliani0.053
NLazNeural Lazarillo0.049
porinCG6647 gene product from transcript CG6647-RA0.048
CG6660CG6660 gene product from transcript CG6660-RA0.038
vvermilion0.032
trpmltransient receptor potential mucolipin0.030
msl-2male-specific lethal 20.027
fs(1)Ybfemale sterile (1) Yb0.027
mex1midgut expression 10.026
AldhAldehyde dehydrogenase0.025
Ppat-DpckBifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase0.025
AdoRAdenosine receptor0.021
Pink1PTEN-induced putative kinase 10.021
HtrA2CG8464 gene product from transcript CG8464-RA0.020
CG17374CG17374 gene product from transcript CG17374-RB0.019
DJ-1alphaCG6646 gene product from transcript CG6646-RA0.017
CG9171CG9171 gene product from transcript CG9171-RC0.016
bwabrain washing0.016
IP3K1Inositol 1,4,5-triphosphate kinase 10.016
Tom34Translocase of outer membrane 340.016
Mmp1Matrix metalloproteinase 10.015
CG4572CG4572 gene product from transcript CG4572-RD0.015
TazTafazzin0.015
ATP7CG1886 gene product from transcript CG1886-RB0.014
cadcaudal0.014
Adgf-AAdenosine deaminase-related growth factor A0.014
AtetABC transporter expressed in trachea0.013
LaspCG3849 gene product from transcript CG3849-RB0.013
slboslow border cells0.012
CG10992CG10992 gene product from transcript CG10992-RA0.012
CatsupCatecholamines up0.012
Hr4CG16902 gene product from transcript CG16902-RC0.011
CG12030CG12030 gene product from transcript CG12030-RA0.011
picoCG11940 gene product from transcript CG11940-RA0.011
CG17181CG17181 gene product from transcript CG17181-RA0.010
MtpMicrosomal triacylglycerol transfer protein0.010
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)1.000
FYNFYN oncogene related to SRC, FGR, YES0.999
LCKlymphocyte-specific protein tyrosine kinase0.881
HCKhemopoietic cell kinase0.824
SYKspleen tyrosine kinase0.315
UBASH3Bubiquitin associated and SH3 domain containing B0.250
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.250
SPRR2Asmall proline-rich protein 2A0.191
PSTPIP1proline-serine-threonine phosphatase interacting protein 10.174
NCK1NCK adaptor protein 10.169
SH3KBP1SH3-domain kinase binding protein 10.158
ZAP70zeta-chain (TCR) associated protein kinase 70kDa0.147
GRB7growth factor receptor-bound protein 70.136
ITKIL2-inducible T-cell kinase0.109
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.083
GAS7growth arrest-specific 70.066
LASS2LAG1 homolog, ceramide synthase 20.062
GRB2growth factor receptor-bound protein 20.055
VAV1vav 1 guanine nucleotide exchange factor0.048
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.041
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.040
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.040
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.038
BLNKB-cell linker0.033
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.030
PRKCQprotein kinase C, theta0.027
CD247CD247 molecule0.026
PDCD6programmed cell death 60.024
PRRC1proline-rich coiled-coil 10.024
PLCG1phospholipase C, gamma 10.024
TMC8transmembrane channel-like 80.024
BTKBruton agammaglobulinemia tyrosine kinase0.021
PDCD2programmed cell death 20.021
PTK2BPTK2B protein tyrosine kinase 2 beta0.021
DLG4discs, large homolog 4 (Drosophila)0.021
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.020
BCAR1breast cancer anti-estrogen resistance 10.020
PINK1PTEN induced putative kinase 10.020
C19orf6chromosome 19 open reading frame 60.020
CANXcalnexin0.019
RGS14regulator of G-protein signaling 140.019
YES1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.019
CD79ACD79a molecule, immunoglobulin-associated alpha0.018
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.018
DOK1docking protein 1, 62kDa (downstream of tyrosine kinase 1)0.017
PDCD6IPprogrammed cell death 6 interacting protein0.017
TNS3tensin 30.016
PIK3R3phosphoinositide-3-kinase, regulatory subunit 3 (gamma)0.016
SNX33sorting nexin 330.016
SRCIN1SRC kinase signaling inhibitor 10.014
ITGALintegrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)0.014
TMC6transmembrane channel-like 60.013
TM9SF3transmembrane 9 superfamily member 30.013
DNAJC10DnaJ (Hsp40) homolog, subfamily C, member 100.013
FBXO7F-box protein 70.012
UBASH3Aubiquitin associated and SH3 domain containing A0.012
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.012
MUC1mucin 1, cell surface associated0.011
MFAP3microfibrillar-associated protein 30.011
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.011
HMHA1histocompatibility (minor) HA-10.011
PACSIN3protein kinase C and casein kinase substrate in neurons 30.010
EDEM3ER degradation enhancer, mannosidase alpha-like 30.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Mt1metallothionein 11.000
Mt2metallothionein 21.000
Nfe2l2nuclear factor, erythroid derived 2, like 20.522
Atp7bATPase, Cu++ transporting, beta polypeptide0.363
Cd8aCD8 antigen, alpha chain0.352
Apoeapolipoprotein E0.208
Slc31a1solute carrier family 31, member 10.185
Hps4Hermansky-Pudlak syndrome 4 homolog (human)0.111
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.111
Ptprcapprotein tyrosine phosphatase, receptor type, C polypeptide-associated protein0.103
Tgfbr1transforming growth factor, beta receptor I0.097
Latlinker for activation of T cells0.091
Cd2apCD2-associated protein0.076
Slc39a4solute carrier family 39 (zinc transporter), member 40.060
Cd4CD4 antigen0.047
Steap3STEAP family member 30.045
Atox1ATX1 (antioxidant protein 1) homolog 1 (yeast)0.039
Ptprcprotein tyrosine phosphatase, receptor type, C0.037
Zap70zeta-chain (TCR) associated protein kinase0.037
Uso1USO1 homolog, vesicle docking protein (yeast)0.035
Uba5ubiquitin-like modifier activating enzyme 50.027
Zc3h3zinc finger CCCH type containing 30.027
Mfn2mitofusin 20.025
FasFas (TNF receptor superfamily member 6)0.024
Sco2SCO cytochrome oxidase deficient homolog 2 (yeast)0.024
H47histocompatibility 470.022
Tgfbr2transforming growth factor, beta receptor II0.021
Nell2NEL-like 2 (chicken)0.020
Stt3aSTT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)0.019
Tram1translocating chain-associating membrane protein 10.019
Mutedmuted0.019
Cluclusterin0.019
Inpp5jinositol polyphosphate 5-phosphatase J0.019
Plcg1phospholipase C, gamma 10.018
Gpr98G protein-coupled receptor 980.017
Efemp2epidermal growth factor-containing fibulin-like extracellular matrix protein 20.016
Slc4a7solute carrier family 4, sodium bicarbonate cotransporter, member 70.016
Il2rbinterleukin 2 receptor, beta chain0.015
Myh9myosin, heavy polypeptide 9, non-muscle0.014
Sec24dSec24 related gene family, member D (S. cerevisiae)0.014
Sdc4syndecan 40.013
Cnocappuccino0.013
Cstbcystatin B0.013
Ccdc114coiled-coil domain containing 1140.012
Cpceruloplasmin0.011
Pcsk4proprotein convertase subtilisin/kexin type 40.011
Soat2sterol O-acyltransferase 20.011
Chmp1bchromatin modifying protein 1B0.011
Dnajc3DnaJ (Hsp40) homolog, subfamily C, member 30.011
Tuba8tubulin, alpha 80.010
Fut8fucosyltransferase 80.010
FynFyn proto-oncogene0.010
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism