The network for 'negative regulation of rna metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of rna metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.

NameDescriptionProbabilityFunc Analog Organism
RPD3Rpd3p0.999
HHF1Hhf1p0.998
SIR2Sir2p0.995
HHT1Hht1p0.995
SIN3Sin3p0.991
RAP1Rap1p0.989
HDA1Hda1p0.988
RLF2Rlf2p0.982
SIR4Sir4p0.981
CTI6Cti6p0.979
RXT2Rxt2p0.971
CTK1Ctk1p0.970
RCO1Rco1p0.966
SIN4Sin4p0.966
ORC2Orc2p0.961
YTA7Yta7p0.957
RTT106Rtt106p0.950
HAT1Hat1p0.949
HMO1Hmo1p0.947
RIF1Rif1p0.939
SUM1Sum1p0.937
SDS3Sds3p0.934
PHO23Pho23p0.905
FKH2Fkh2p0.899
ISW2Isw2p0.878
CYC8Cyc8p0.875
ORC5Orc5p0.875
RPN4Rpn4p0.866
GLC7Glc7p0.864
SET1Set1p0.847
ASF1Asf1p0.834
GBP2Gbp2p0.828
YAK1Yak1p0.818
HTB1Htb1p0.813
PGD1Pgd1p0.783
SAS2Sas2p0.781
ROX3Rox3p0.781
ADR1Adr1p0.772
NAT1Nat1p0.768
MED2Med2p0.766
CSE2Cse2p0.765
GLN3Gln3p0.759
ZDS1Zds1p0.744
HOG1Hog1p0.732
HIR1Hir1p0.714
SNT1Snt1p0.698
GCN5Gcn5p0.696
ARP4Arp4p0.688
CDC45Cdc45p0.686
SAS4Sas4p0.680
DOA1Doa1p0.680
RSC4Rsc4p0.679
VPS36Vps36p0.658
UBP8Ubp8p0.653
RGR1Rgr1p0.652
GAL11Gal11p0.648
SNF5Snf5p0.642
MET4Met4p0.642
BDF1Bdf1p0.641
DOT6Dot6p0.639
SPT10Spt10p0.639
UME1Ume1p0.636
ITC1Itc1p0.636
YCS4Ycs4p0.625
GCR2Gcr2p0.622
HCM1Hcm1p0.610
STM1Stm1p0.606
HDA3Hda3p0.603
ADA2Ada2p0.601
SWD1Swd1p0.598
LGE1Lge1p0.595
FOB1Fob1p0.585
DEP1Dep1p0.579
RTF1Rtf1p0.573
HRK1Hrk1p0.572
SSN3Ssn3p0.572
SET2Set2p0.568
SAP30Sap30p0.566
SIR3Sir3p0.550
RIM101Rim101p0.546
NRG1Nrg1p0.544
HHF2Hhf2p0.541
ISW1Isw1p0.538
CDC6Cdc6p0.538
MOT3Mot3p0.537
HAT2Hat2p0.534
IZH4Izh4p0.533
VHS1Vhs1p0.531
SLX5Slx5p0.517
AFT1Aft1p0.517
CCR4Ccr4p0.510
RLM1Rlm1p0.507
HTZ1Htz1p0.504
SPT21Spt21p0.503
CDC14Cdc14p0.499
NHP6ANhp6ap0.499
HTA1Hta1p0.484
NUT2Nut2p0.483
TOR1Tor1p0.483
CHD1Chd1p0.478
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.945
pha-4Protein PHA-40.595
elt-6Protein ELT-60.429
his-1Protein HIS-10.357
rad-26Protein RAD-260.285
his-68Protein HIS-680.244
his-16Protein HIS-160.238
let-502Protein LET-5020.224
lin-53Protein LIN-530.193
egl-13Protein EGL-130.183
mes-4Protein MES-40.172
egl-46Protein EGL-460.165
mat-3Protein MAT-30.161
his-5Protein HIS-50.156
his-31Protein HIS-310.151
wrm-1Protein WRM-10.150
his-64Protein HIS-640.146
attf-2Protein ATTF-20.146
his-61Protein HIS-610.143
pry-1Protein PRY-10.136
atg-2Protein ATG-20.129
his-62Protein HIS-620.128
his-46Protein HIS-460.123
zip-7Protein ZIP-70.121
unc-62Protein UNC-620.121
Y17G7B.20Protein Y17G7B.200.119
prp-8Protein PRP-80.118
his-47Protein HIS-470.114
CELE_F19F10.9Protein F19F10.90.114
lin-11Protein LIN-110.113
his-48Protein HIS-480.109
tbx-8Protein TBX-80.107
let-418Protein LET-4180.107
mep-1Protein MEP-10.106
ran-1Protein RAN-10.105
his-3Protein HIS-30.104
hlh-2Protein HLH-20.104
fkb-6Protein FKB-60.101
aph-2Protein APH-20.100
skp-1Protein SKP-10.099
CELE_W03F9.10Protein W03F9.100.092
lin-66Protein LIN-660.092
hda-1Protein HDA-10.090
ceh-38Protein CEH-380.090
F39B2.1Protein F39B2.10.090
his-38Protein HIS-380.090
eya-1Protein EYA-10.090
CELE_C12D8.1Protein C12D8.10.089
lin-1Protein LIN-10.085
ceh-32Protein CEH-320.082
ceh-27Protein CEH-270.079
egl-38Protein EGL-380.078
mls-2Protein MLS-20.076
his-52Protein HIS-520.076
hlh-11Protein HLH-110.076
csn-4Protein CSN-40.074
his-30Protein HIS-300.073
lin-17Protein LIN-170.071
hda-3Protein HDA-30.068
rsp-1Protein RSP-10.067
CELE_Y41E3.11Protein Y41E3.110.067
his-29Protein HIS-290.067
lin-12Protein LIN-120.067
T20F7.1Protein T20F7.10.066
hum-5Protein HUM-50.066
plc-1Protein PLC-10.064
his-51Protein HIS-510.063
nhr-67Protein NHR-670.062
mcm-2Protein MCM-20.061
his-50Protein HIS-500.060
prpf-4Protein PRPF-40.060
rpa-2Protein RPA-20.059
T28C6.7Protein T28C6.70.059
F33H2.3Protein F33H2.30.059
mix-1Protein MIX-10.059
his-15Protein HIS-150.058
mcm-4Protein MCM-40.057
his-4Protein HIS-40.056
D2096.7Protein D2096.70.055
bar-1Protein BAR-10.054
klp-19Protein KLP-190.053
dcr-1Protein DCR-10.053
mrpl-18Protein MRPL-180.053
T09B4.5Protein T09B4.50.053
eor-1Protein EOR-10.053
C27F2.8Protein C27F2.80.053
pax-3Protein PAX-30.053
Y42H9AR.4Protein Y42H9AR.40.053
F55F8.9Protein F55F8.90.052
qua-1Protein QUA-10.052
hlh-1Protein HLH-10.052
daf-1Protein DAF-10.051
ztf-2Protein ZTF-20.051
hbl-1Protein HBL-10.050
frm-7Protein FRM-70.050
bet-1Protein BET-10.050
swsn-4Protein SWSN-40.050
cpf-2Protein CPF-20.050
rskn-2Protein RSKN-20.050
C46F11.4Protein C46F11.40.049
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
gli1GLI-Kruppel family member 10.926
ndr2nodal-related 20.917
jag2jagged 20.812
lhx1aLIM homeobox 1a0.759
mab21l2mab-21-like 20.746
snai1bsnail homolog 1b (Drosophila)0.710
bmp2bbone morphogenetic protein 2b0.666
chdchordin0.611
fgf3fibroblast growth factor 30.570
dlx2adistal-less homeobox gene 2a0.565
gata6GATA-binding protein 60.563
wt1awilms tumor 1a0.563
mecomMDS1 and EVI1 complex locus0.557
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.551
sox32SRY-box containing gene 320.528
hnf1baHNF1 homeobox Ba0.507
twist3twist30.498
fstafollistatin a0.493
lef1lymphocyte enhancer binding factor 10.447
flhfloating head0.421
tll1tolloid-like 10.386
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.365
per2period homolog 2 (Drosophila)0.357
gro1groucho 10.350
pax8paired box gene 80.346
fzd8afrizzled homolog 8a0.345
foxi1forkhead box I10.302
dlcdeltaC0.291
zic5zic family member 5 (odd-paired homolog, Drosophila)0.277
grem2gremlin 2, cysteine knot superfamily0.269
runx1runt-related transcription factor 10.268
six3bsine oculis homeobox homolog 3b0.257
sox19aSRY-box containing gene 19a0.253
meis3myeloid ecotropic viral integration site 30.252
isl1islet10.251
tac1tachykinin 10.243
pcnaproliferating cell nuclear antigen0.241
klf4aKruppel-like transcription factor 4a0.233
otx2orthodenticle homolog 20.231
znfl2azinc finger-like gene 2a0.226
wnt5bwingless-type MMTV integration site family, member 5b0.226
zic2bzic family member 2 (odd-paired homolog, Drosophila) b0.223
aldh1a2aldehyde dehydrogenase 1 family, member A20.222
khdrbs1aKH domain containing, RNA binding, signal transduction associated 1a0.217
vcanaversican a0.214
bmp4bone morphogenetic protein 40.213
spawsouthpaw0.213
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.211
meis2.1myeloid ecotropic viral integration site 2.10.210
wnt1wingless-type MMTV integration site family, member 10.210
socs3asuppressor of cytokine signaling 3a0.209
hoxb1bhomeo box B1b0.203
eomesaeomesodermin homolog a0.202
sox9bSRY-box containing gene 9b0.199
rorcaRAR-related orphan receptor C a0.198
lft2lefty20.198
lhx5LIM homeobox 50.195
pou3f2POU class 3 homeobox 20.194
prox1prospero-related homeobox gene 10.193
whsc1Wolf-Hirschhorn syndrome candidate 10.189
her7hairy and enhancer of split related-70.188
pdlim7PDZ and LIM domain 70.183
tfap2atranscription factor AP-2 alpha0.182
cdx4caudal type homeo box transcription factor 40.181
sesn1sestrin 10.179
insm1binsulinoma-associated 1b0.176
rargaretinoic acid receptor gamma a0.174
ntlano tail a0.170
sox1aSRY-box containing gene 1a0.163
atoh7atonal homolog 70.163
pax6apaired box gene 6a0.163
ptf1apancreas specific transcription factor, 1a0.162
dctdopachrome tautomerase0.161
hmx1H6 homeo box 10.160
dlx5adistal-less homeobox gene 5a0.158
nkx2.1aNK2 homeobox 1a0.158
snai1asnail homolog 1a (Drosophila)0.157
flt4fms-related tyrosine kinase 40.153
neurog1neurogenin 10.150
ephb3aeph receptor B3a0.150
her1hairy-related 10.148
otx1borthodenticle homolog 1b0.147
junbjun B proto-oncogene0.147
pcdh8protocadherin 80.146
cry3cryptochrome 30.144
rarabretinoic acid receptor, alpha b0.143
otx5orthodenticle homolog 50.141
ascl1bachaete-scute complex-like 1b (Drosophila)0.139
dusp6dual specificity phosphatase 60.139
id1inhibitor of DNA binding 10.139
has2hyaluronan synthase 20.139
plekhg4pleckstrin homology domain containing, family G (with RhoGef domain) member 40.135
traf4atnf receptor-associated factor 4a0.134
nkx2.5NK2 transcription factor related 50.133
ddx39bDEAD (Asp-Glu-Ala-Asp) box polypeptide 39b0.132
sall1asal-like 1a (Drosophila)0.130
vsx1visual system homeobox 1 homolog, chx10-like0.130
tyrtyrosinase0.129
hmx4H6 family homeobox 40.129
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.129
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
grogroucho1.000
CTCFCG8591 gene product from transcript CG8591-RA0.999
IswiImitation SWI0.999
Abd-BAbdominal B0.998
ScmSex comb on midleg0.998
Su(var)205Suppressor of variegation 2050.998
ushu-shaped0.996
UbxUltrabithorax0.992
hephemipterous0.992
Snr1Snf5-related 10.990
hthhomothorax0.989
tlltailless0.988
kaykayak0.987
Su(H)Suppressor of Hairless0.982
His2AvHistone H2A variant0.982
atoatonal0.978
E(spl)Enhancer of split0.975
dshdishevelled0.969
gppgrappa0.958
Sir2CG5216 gene product from transcript CG5216-RA0.957
gsbgooseberry0.954
ash1absent, small, or homeotic discs 10.952
smt3CG4494 gene product from transcript CG4494-RA0.940
D1D1 chromosomal protein0.939
CtBPC-terminal Binding Protein0.934
rinrasputin0.928
slp1sloppy paired 10.928
dcodiscs overgrown0.927
bcdbicoid0.925
cicubitus interruptus0.925
araaraucan0.924
OptixCG18455 gene product from transcript CG18455-RA0.923
emcextra macrochaetae0.921
prdpaired0.918
Trf2TATA box binding protein-related factor 20.917
spensplit ends0.912
pr-set7CG3307 gene product from transcript CG3307-RC0.909
mammastermind0.904
KrKruppel0.904
MadMothers against dpp0.904
nubnubbin0.899
PclPolycomblike0.891
dacdachshund0.885
CycBCyclin B0.882
C15CG7937 gene product from transcript CG7937-RA0.882
runrunt0.876
shnschnurri0.875
hhhedgehog0.875
E(var)3-9Enhancer of variegation 3-90.872
Pp1-87BProtein phosphatase 1 at 87B0.871
Pka-C1cAMP-dependent protein kinase 10.870
snostrawberry notch0.864
salmspalt major0.863
barrbarren0.862
Ten-mTenascin major0.859
snasnail0.859
Dsp1Dorsal switch protein 10.857
Hel25EHelicase at 25E0.856
brkbrinker0.851
Acf1ATP-dependent chromatin assembly factor large subunit0.847
BEAF-32Boundary element-associated factor of 32kD0.845
MedMedea0.844
aopanterior open0.840
eyeyeless0.833
Nf-YCNuclear factor Y-box C0.830
osaCG7467 gene product from transcript CG7467-RD0.827
reptreptin0.826
ssspineless0.825
InRInsulin-like receptor0.822
abd-Aabdominal A0.819
sxcsuper sex combs0.817
eyaeyes absent0.815
HLHm7E(spl) region transcript m70.814
eygeyegone0.805
alaristaless0.802
Eip63EEcdysone-induced protein 63E0.795
sdscalloped0.792
pbproboscipedia0.791
Doc2Dorsocross20.785
invinvected0.777
oddodd skipped0.773
p53CG33336 gene product from transcript CG33336-RB0.772
trxtrithorax0.767
bratbrain tumor0.766
SceSex combs extra0.761
vgvestigial0.758
PcPolycomb0.757
bowlbrother of odd with entrails limited0.753
frufruitless0.751
Su(var)3-7Suppressor of variegation 3-70.750
Akt1CG4006 gene product from transcript CG4006-RA0.744
eastenhanced adult sensory threshold0.742
HGTXCG13475 gene product from transcript CG13475-RB0.739
esgescargot0.735
RbfRetinoblastoma-family protein0.730
phylphyllopod0.730
wocwithout children0.727
dallydivision abnormally delayed0.727
hbhunchback0.725
slislit0.717
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Tcf4transcription factor 40.891
Junbjun B proto-oncogene0.834
JunJun oncogene0.812
Ier2immediate early response 20.710
Btg2BTG family, member 20.705
Tgfbr2transforming growth factor, beta receptor II0.619
Ppp2cbprotein phosphatase 2, catalytic subunit, beta isoform0.598
Tcfe2atranscription factor E2a0.572
Zfp36zinc finger protein 360.541
Metmet proto-oncogene0.460
Trim28tripartite motif-containing 280.452
Nfibnuclear factor I/B0.451
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.441
Ascl1achaete-scute complex homolog 1 (Drosophila)0.419
Dusp1dual specificity phosphatase 10.417
RGD1565591similar to Ski protein0.414
Kcnt1potassium channel, subfamily T, member 10.405
Hnrnprheterogeneous nuclear ribonucleoprotein R0.404
Siah1aseven in absentia 1A0.394
Purbpurine rich element binding protein B0.388
Pgam1phosphoglycerate mutase 1 (brain)0.353
Nr4a1nuclear receptor subfamily 4, group A, member 10.345
Dab2disabled homolog 2 (Drosophila)0.344
S100a8S100 calcium binding protein A80.332
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.330
Slc4a1solute carrier family 4 (anion exchanger), member 10.323
Smad7SMAD family member 70.307
Vimvimentin0.304
Neurog1neurogenin 10.294
Hes1hairy and enhancer of split 1 (Drosophila)0.286
Ptmaprothymosin alpha0.285
Tcp11t-complex protein 110.283
Gata6GATA binding protein 60.282
Kdm6blysine (K)-specific demethylase 6B0.273
Anp32eacidic (leucine-rich) nuclear phosphoprotein 32 family, member E0.270
Hoxd3homeo box D30.268
S100a9S100 calcium binding protein A90.253
Cxxc5CXXC finger 50.243
Rararetinoic acid receptor, alpha0.241
Id1inhibitor of DNA binding 10.238
Nfianuclear factor I/A0.233
Ppm1gprotein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform0.230
Mybl2myeloblastosis oncogene-like 20.228
Klf2Kruppel-like factor 2 (lung)0.227
CtcfCCCTC-binding factor (zinc finger protein)0.226
RestRE1-silencing transcription factor0.225
Hnrnpkheterogeneous nuclear ribonucleoprotein K0.225
FosFBJ osteosarcoma oncogene0.223
Pcnaproliferating cell nuclear antigen0.221
Pfkfb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 20.217
Ccnd1cyclin D10.215
Wbp11WW domain binding protein 110.215
Ubtfupstream binding transcription factor, RNA polymerase I0.215
Ptprkprotein tyrosine phosphatase, receptor type, K, extracellular region0.214
Alx1ALX homeobox 10.213
Notch1Notch homolog 1, translocation-associated (Drosophila)0.210
Anxa5annexin A50.206
Dynll1dynein light chain LC8-type 10.205
Eif4heukaryotic translation initiation factor 4H0.204
Drd3dopamine receptor D30.204
Foxd1forkhead box D10.203
DbpD site of albumin promoter (albumin D-box) binding protein0.197
Hmgb1high mobility group box 10.196
Usf2upstream transcription factor 2, c-fos interacting0.191
Nfyanuclear transcription factor-Y alpha0.190
Crybb3crystallin, beta B30.190
Slc6a6solute carrier family 6 (neurotransmitter transporter, taurine), member 60.190
Grk1G protein-coupled receptor kinase 10.185
Myh9myosin, heavy chain 9, non-muscle0.184
Nedd4neural precursor cell expressed, developmentally down-regulated 40.182
Pde4bphosphodiesterase 4B, cAMP specific0.179
Foxi2forkhead box I20.177
Sox7SRY (sex determining region Y)-box 70.177
Abcb4ATP-binding cassette, subfamily B (MDR/TAP), member 40.176
Hoxc4homeo box C40.176
Kif1ckinesin family member 1C0.174
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.171
Hist1h1dhistone cluster 1, H1d0.171
Mllt4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.170
Ptpn1protein tyrosine phosphatase, non-receptor type 10.170
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.170
Dlx5distal-less homeobox 50.170
Ifitm3interferon induced transmembrane protein 30.168
Socs3suppressor of cytokine signaling 30.168
Pparaperoxisome proliferator activated receptor alpha0.166
Prdm12PR domain containing 120.165
Nr1d2nuclear receptor subfamily 1, group D, member 20.163
Arf6ADP-ribosylation factor 60.163
Dlg1discs, large homolog 1 (Drosophila)0.162
Irf1interferon regulatory factor 10.162
Baiap2BAI1-associated protein 20.161
Hsd3b6hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 60.160
Tmpothymopoietin0.159
Il1ainterleukin 1 alpha0.156
Eif1eukaryotic translation initiation factor 10.154
Hnrnpabheterogeneous nuclear ribonucleoprotein A/B0.153
Jak1Janus kinase 10.153
Klf4Kruppel-like factor 4 (gut)0.152
Sf1splicing factor 10.151
RalyRNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))0.151